{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:09:57Z","timestamp":1773288597046,"version":"3.50.1"},"reference-count":22,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Parasitic contamination in vegetables is a reality in several countries and a challenge for food safety. The risk of consumption usually raw, associated with failures in good practices of production, transportation, and preparation further increase the possibility of ingesting contaminated food. Given this, a systematic review was carried out to scientifically demonstrate the effectiveness of sanitization protocols in the parasitic decontamination of plants.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods<\/jats:title><jats:p>This review was conducted following the guidelines of the Cochrane Manual, being registered in the PROSPERO protocol base (CRD42020206929) and reported according to the PRISMA 2020 statement. The review evaluated studies published in the MEDLINE, Embase, Web of Science, FSTA, LILACS, and AGRIS databases, as well as manual searches of related articles, references, and theses and dissertations directories. The meta-analysis was performed using the Revman 5 software program, the bias assessment used the Robins I Tools with some adaptations, and the quality of the evidence was evaluated using GRADE.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Discussion<\/jats:title><jats:p>The review included a total of 31 studies, most of which were carried out in countries with a high incidence of plant parasites, such as Brazil and Iran. Interventions combined with 200ppm chlorination preceded by brushing, rinsing, or immersion in detergent showed the greatest efficiency in parasitic decontamination. Despite the high heterogeneity and risk of bias in the primary studies, this review can inspire the planning of new studies which observe the critical and methodological evaluation for research in the field of food safety.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0290447","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T17:25:48Z","timestamp":1693589148000},"page":"e0290447","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of sanitization protocols in removing or reducing parasites from vegetables: A systematic review with meta-analysis"],"prefix":"10.1371","volume":"18","author":[{"given":"Cl\u00e1udio M\u00e1rcio de Medeiros","family":"Maia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6884-1023","authenticated-orcid":true,"given":"Karla Suzanne Florentino da Silva Chaves","family":"Damasceno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1878-4283","authenticated-orcid":true,"given":"Larissa Mont\u2019Alverne Juc\u00e1","family":"Seabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Chaves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00edvia Maria da Costa","family":"Dantas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2042-4348","authenticated-orcid":true,"given":"Francisco Canind\u00e9 de","family":"Sousa J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7595-5395","authenticated-orcid":true,"given":"Cristiane Fernandes","family":"de Assis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,9,1]]},"reference":[{"key":"pone.0290447.ref001","article-title":"Prevalence of helminths in fresh vegetables: a narrative literature review","author":"LMC Dantas","year":"2023","journal-title":"J Sci Food Agric"},{"issue":"1","key":"pone.0290447.ref002","first-page":"1","article-title":"Detection of human intestinal protozoan parasites in vegetables and fruits: a review","volume":"380","author":"J Li","year":"2020","journal-title":"Parasites and Vectors"},{"issue":"February","key":"pone.0290447.ref003","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.tifs.2020.03.011","article-title":"Parasite detection in food: Current status and future needs for validation","volume":"99","author":"RM Chalmers","year":"2020","journal-title":"Trends Food Sci Technol"},{"key":"pone.0290447.ref004","first-page":"82","article-title":"Parasitic contamination of fresh vegetables sold in open markets: a public health threat.","author":"W Khan","year":"2022","journal-title":"Brazilian Journal of Biology"},{"key":"pone.0290447.ref005","first-page":"95","article-title":"Zoonotic parasitic organisms on vegetables: Impact of production system characteristics on presence, prevalence on vegetables in northwestern Iran and washing methods for removal","author":"N Hajipour","year":"2021","journal-title":"Food Microbiology"},{"key":"pone.0290447.ref006","first-page":"208","article-title":"How globalization and climate change could affect foodborne parasites","author":"E. 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