{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:40:01Z","timestamp":1791337201396,"version":"4.3.1"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["#301967\/2022-9"],"award-info":[{"award-number":["#301967\/2022-9"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["#E-26\/010.002124\/2019, #E-26\/211.187\/2021, #E-26\/211.104\/2021, and #E-26\/200.929\/2022"],"award-info":[{"award-number":["#E-26\/010.002124\/2019, #E-26\/211.187\/2021, #E-26\/211.104\/2021, and #E-26\/200.929\/2022"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["FinanceCode 001, 88881.708719\/2022-01, and 88887.708718\/2022-00"],"award-info":[{"award-number":["FinanceCode 001, 88881.708719\/2022-01, and 88887.708718\/2022-00"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Post-tuberculosis bronchiectasis (PTBB) is gaining recognition as an important chronic lung disease, representing a neglected condition with a significant burden for the individual. Recently, the Glittre-ADL test (TGlittre) has been proposed for the assessment of functional capacity, which incorporates tasks of daily living demanding the upper and lower extremities. This study used TGlittre to compare patients with PTBB to patients with non-post-tuberculosis bronchiectasis (NPTBB) and evaluate the determinants of performance during TGlittre.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This is a cross-sectional study in which 32 patients with PTBB and 29 with NPTBB underwent TGlittre. In addition, they completed Short Form-36 (SF-36), handgrip strength, quadriceps muscle strength (QMS) and pulmonary function tests (PFTs).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Both PTBB and NPTBB required much more time to perform the TGlittre compared to the predicted values, although they did not differ statistically from each other [152 (124\u2013200) vs. 145 (117\u2013179)% predicted, p = 0.41]. Regarding the PFTs, the PTBB participants showed significantly lower values than the NPTBB participants in forced vital capacity (FVC, 60 \u00b1 14.5 vs. 78.2 \u00b1 22.2% predicted, p&lt;0.001) and total lung capacity [82 (66\u201395) vs. 93 (82\u2013105)% predicted, p = 0.028]. In the PTBB group, FVC (p&lt;0.001) and QMS (p = 0.001) were the only significant independent variables to predict TGlittre time, explaining 71% of the variability in TGlittre time. In the NPTBB group, maximal expiratory pressure (p = 0.002), residual volume\/TLC (p = 0.001) and QMS (p = 0.032) were the significant independent variables for predicting TGlittre time, explaining 73% of the variability in TGlittre time.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>PTBB patients have lower than expected performance on TGlittre, though similar to NPTBB patients. The PTBB patients had a greater reduction in lung volume than NPTBB patients. Furthermore, the performance on TGlittre in PTBB patients is largely explained by lung volume and QMS.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0290850","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T17:25:53Z","timestamp":1693589153000},"page":"e0290850","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Performance during the Glittre-ADL test between patients with and without post-tuberculosis bronchiectasis: A cross-sectional study"],"prefix":"10.1371","volume":"18","author":[{"given":"Cristiane Pires","family":"Motta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davi Luiz","family":"Olimpio da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lohana Resende","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giselle Faria","family":"Galhardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8598-4878","authenticated-orcid":true,"given":"Agnaldo Jos\u00e9","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,9,1]]},"reference":[{"key":"pone.0290850.ref001","article-title":"Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)","author":"JD Chalmers","year":"2023","journal-title":"The Lancet Respiratory Medicine"},{"issue":"3","key":"pone.0290850.ref002","doi-asserted-by":"crossref","first-page":"1700629","DOI":"10.1183\/13993003.00629-2017","article-title":"European Respiratory Society guidelines for the management of adult bronchiectasis","volume":"50","author":"E Polverino","year":"2017","journal-title":"The European Respiratory Journal"},{"issue":"1","key":"pone.0290850.ref003","doi-asserted-by":"crossref","first-page":"2201977","DOI":"10.1183\/13993003.01977-2022","article-title":"Bronchiectasis in low- and middle-income countries: the importance of the wider view","volume":"61","author":"JS Brown","year":"2023","journal-title":"The European Respiratory Journal"},{"issue":"4","key":"pone.0290850.ref004","doi-asserted-by":"crossref","first-page":"177","DOI":"10.5694\/mja17.01195","article-title":"Management of bronchiectasis in adults","volume":"209","author":"SK Visser","year":"2018","journal-title":"The Medical Journal of Australia"},{"key":"pone.0290850.ref005","volume-title":"Tuberculosis deaths and disease increase during the COVID-19 pandemic","author":"C. 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