{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T15:03:43Z","timestamp":1783004623376,"version":"3.54.5"},"reference-count":15,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T00:00:00Z","timestamp":1694131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Spontaneous pneumothorax occurs predominantly in young males and older adults, often as a secondary condition, and can be refractory and fatal. This study aimed to investigate the mortality and prognostic factors for pneumothorax in older patients. We retrospectively cohort studied patients with pneumothorax aged \u226565 years who visited our department from October 2012 to January 2019. Data on sex, age, medical history, smoking history, underlying lung disease, treatment, and prognosis were extracted from medical records. Cox proportional hazards regression analysis was used to investigate pneumothorax mortality and prognostic factors. In total, 239 patients were included. Among them, 36 (15%) died during hospitalization. Respiratory disease was the direct cause of death in 30 patients (83.3%), and 211 (88.3%) patients had underlying lung disease. The incidence of pneumonia in our hospital was 22.6% (54 cases). On admission, the mortality rate was 33% (18\/54) in patients with concomitant pneumonia; univariate analysis showed significant differences in the Charlson Comorbidity Index (CCI), activities of daily living (ADL), and concomitant pneumonia. In the Cox proportional hazards analysis of ADL (p = 0.09), CCI (p = 0.05), and concomitant pneumonia on admission (p = 0.02), concomitant pneumonia on admission was found to be an independent predictor of in-hospital mortality. This study suggests that concomitant pneumonia at admission may be a mortality risk factor for pneumothorax.<\/jats:p>","DOI":"10.1371\/journal.pone.0291233","type":"journal-article","created":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T17:43:16Z","timestamp":1694194996000},"page":"e0291233","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Mortality and prognostic factors for spontaneous pneumothorax in older adults"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3040-0756","authenticated-orcid":true,"given":"Saori","family":"Nishizawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Tobino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousuke","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafumi","family":"Kawabata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Hiramatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuto","family":"Sueyasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Tsuruno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,9,8]]},"reference":[{"issue":"10","key":"pone.0291233.ref001","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1111\/ggi.13996","article-title":"Etiology and prognosis of spontaneous pneumothorax in the elderly","volume":"20","author":"F Takahashi","year":"2020","journal-title":"Geriatr Gerontol Int"},{"issue":"12","key":"pone.0291233.ref002","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1056\/NEJM200003233421207","article-title":"Spontaneous pneumothorax","volume":"342","author":"SA Sahn","year":"2000","journal-title":"N Engl J Med"},{"issue":"117","key":"pone.0291233.ref003","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1183\/09059180.00005310","article-title":"Spontaneous pneumothorax: epidemiology, pathophysiology and cause","volume":"19","author":"M. Noppen","year":"2010","journal-title":"Eur Respir Rev"},{"key":"pone.0291233.ref004","doi-asserted-by":"crossref","first-page":"6014967","DOI":"10.1155\/2017\/6014967","article-title":"Primary and Secondary Spontaneous Pneumothorax: Prevalence, Clinical Features, and In-Hospital Mortality","volume":"2017","author":"T Onuki","year":"2017","journal-title":"Can Respir J"},{"key":"pone.0291233.ref005","volume-title":"Terminology, terms, and guidelines for pneumothorax and cystic lung diseases","year":"2009"},{"issue":"2","key":"pone.0291233.ref006","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1378\/chest.119.2.590","article-title":"Management of spontaneous pneumothorax: an American College of Chest Physicians Delphi consensus statement","volume":"119","author":"MH Baumann","year":"2001","journal-title":"Chest"},{"key":"pone.0291233.ref007","first-page":"18","article-title":"Management of spontaneous pneumothorax: British Thoracic Society Pleural Disease Guideline 2010","volume":"652","author":"BTS Pleural Disease Guideline Group","year":"2010","journal-title":"Thorax"},{"key":"pone.0291233.ref008","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software \u2019EZR\u2019 for medical statistics","volume":"48","author":"Y. Kanda","year":"2013","journal-title":"Bone Marrow Transplant"},{"issue":"7","key":"pone.0291233.ref009","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1111\/ggi.13118","article-title":"Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Societyy","volume":"17","author":"Y Ouchi","year":"2017","journal-title":"Geriatr Gerontol Int"},{"key":"pone.0291233.ref010","article-title":"The Aging of Populations and its Economic and Social Implications","volume":"168","author":"PR Cox","year":"1956","journal-title":"New York: United Nations, Department of Economic and Social Affairs"},{"issue":"17","key":"pone.0291233.ref011","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1001\/jama.1990.03450170072025","article-title":"Intrapleural tetracycline for the prevention of recurrent spontaneous pneumothorax. Results of a Department of Veterans Affairs cooperative study","volume":"264","author":"O Light RW","year":"1990","journal-title":"JAMA"},{"issue":"1","key":"pone.0291233.ref012","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ajem.2010.09.014","article-title":"Secondary spontaneous pneumothorax: which associated conditions benefit from pigtail catheter treatment?","volume":"30","author":"CH Chen","year":"2012","journal-title":"Am J Emerg Med"},{"issue":"44","key":"pone.0291233.ref013","first-page":"739","article-title":"Spontaneous Pneumothorax","volume":"114","author":"J Schnell","year":"2017","journal-title":"Dtsch Arztebl Int"},{"issue":"4","key":"pone.0291233.ref014","doi-asserted-by":"crossref","first-page":"1601296","DOI":"10.1183\/13993003.01296-2016","article-title":"Randomised comparison of needle aspiration and chest tube drainage in spontaneous pneumothorax","volume":"49","author":"A Thelle","year":"2017","journal-title":"Eur Respir J"},{"issue":"5","key":"pone.0291233.ref015","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"ME Charlson","year":"1987","journal-title":"J Chronic Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0291233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T17:43:29Z","timestamp":1694195009000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0291233"}},"subtitle":[],"editor":[{"given":"Felix","family":"Bongomin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,9,8]]},"references-count":15,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2023,9,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0291233","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,8]]}}}