{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:08:19Z","timestamp":1740146899536,"version":"3.37.3"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T00:00:00Z","timestamp":1695254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Endowed Research Fund of the University of Alabama School of Social Work"},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P01-AG020166, U19-AG051426"],"award-info":[{"award-number":["P01-AG020166, U19-AG051426"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Despite the rapid rise in opioid prescription medication usage, little research has examined the role of early life adversity, such as childhood abuse, particularly in the context of race, in opioid prescription usage in adulthood. Guided by the life course perspective, the current study investigates whether experiencing childhood abuse increases the risk of opioid prescription use in adulthood and whether this association varies by race. Data were sourced from the second wave of the Midlife in the United States (MIDUS) study (2004\u20132005). The analytic sample consisted of two groups: non-Hispanic Whites (<jats:italic>n<\/jats:italic> = 714) and non-Hispanic Blacks (<jats:italic>n<\/jats:italic> = 151). Opioid prescription use was identified from the participants\u2019 medication list using the MULTUM Lexicon Drug Database Classification System. Three types of childhood abuse\u2014emotional, physical, and sexual\u2014were assessed via summary scales derived from the Childhood Trauma Questionnaire. The results indicate a significant interaction between childhood physical abuse and race. Among non-Hispanic Whites, higher exposure to physical abuse during childhood was associated with greater odds of opioid prescription use in adulthood, even after adjusting for chronic pain, physical and mental health, and sociodemographic characteristics. However, the association between childhood physical abuse and opioid prescription use in adulthood was non-significant among non-Hispanic Black individuals. These findings underscore the long-term adverse health effects of physical abuse in childhood, particularly for non-Hispanic Whites, and suggest support for developing and implementing tailored intervention strategies.<\/jats:p>","DOI":"10.1371\/journal.pone.0291752","type":"journal-article","created":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T17:39:20Z","timestamp":1695317960000},"page":"e0291752","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Childhood abuse and opioid prescription use in adulthood: Differences between non-Hispanic Whites and non-Hispanic Blacks in the United States"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3499-6304","authenticated-orcid":true,"given":"Hee Yun","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6745-1031","authenticated-orcid":true,"given":"Jieun","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7587-6272","authenticated-orcid":true,"given":"Eun Young","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,9,21]]},"reference":[{"key":"pone.0291752.ref001","doi-asserted-by":"crossref","first-page":"ES9","DOI":"10.36076\/ppj.2012\/15\/ES9","article-title":"Opioid epidemic in the United States","volume":"15","author":"L Manchikanti","year":"2012","journal-title":"Pain Physician"},{"journal-title":"2019 Annual surveillance report of drug-related risks and outcomes.","year":"2019","author":"Centers for Disease Control and Prevention","key":"pone.0291752.ref002"},{"key":"pone.0291752.ref003","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1001\/jamapsychiatry.2020.3554","article-title":"Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis","volume":"78","author":"DB Rosoff","year":"2021","journal-title":"JAMA Psychiatry"},{"key":"pone.0291752.ref004","doi-asserted-by":"crossref","first-page":"e1169","DOI":"10.1542\/peds.2015-1364","article-title":"Prescription Opioids in Adolescence and Future Opioid Misuse","volume":"136","author":"R Miech","year":"2015","journal-title":"Pediatrics"},{"key":"pone.0291752.ref005","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1001\/jamapediatrics.2019.4878","article-title":"Association of Opioid Prescribing Patterns With Prescription Opioid Overdose in Adolescents and Young Adults","volume":"174","author":"K-P Chua","year":"2020","journal-title":"JAMA Pediatr"},{"key":"pone.0291752.ref006","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1056\/NEJMra1508490","article-title":"Relationship between Nonmedical Prescription-Opioid Use and Heroin Use","volume":"374","author":"WM Compton","year":"2016","journal-title":"N Engl J Med"},{"key":"pone.0291752.ref007","doi-asserted-by":"crossref","first-page":"349","DOI":"10.15585\/mmwr.mm6712a1","article-title":"Overdose Deaths Involving Opioids, Cocaine, and Psychostimulants\u2014United States, 2015\u20132016.","volume":"67","author":"P Seth","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"pone.0291752.ref008","first-page":"901","volume":"54","author":"CS Florence","year":"2016","journal-title":"The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013: Medical Care."},{"key":"pone.0291752.ref009","doi-asserted-by":"crossref","first-page":"e1910223","DOI":"10.1001\/jamanetworkopen.2019.10223","article-title":"Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands","volume":"2","author":"A Bedene","year":"2019","journal-title":"JAMA Netw Open"},{"key":"pone.0291752.ref010","first-page":"1","article-title":"Prescription opioid analgesic use among adults: United States, 1999\u20132012.","author":"SM Frenk","year":"2015","journal-title":"NCHS Data Brief."},{"key":"pone.0291752.ref011","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1097\/j.pain.0000000000000516","article-title":"Trends and predictors of opioid use after total knee and total hip arthroplasty","volume":"157","author":"J Goesling","year":"2016","journal-title":"Pain"},{"key":"pone.0291752.ref012","doi-asserted-by":"crossref","first-page":"e80095","DOI":"10.1371\/journal.pone.0080095","article-title":"Adverse Selection? 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