{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T06:13:10Z","timestamp":1785219190893,"version":"3.55.0"},"reference-count":19,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Patient-focused evaluation of postoperative recover has been recognized as one of the most important concerns in postoperative medicine. Previous studies have shown that the Quality of Recovery-40 (QoR-40) Questionnaire can be used to accurately assess the quality of recovery from surgery. During thyroid surgery using intraoperative neuromonitoring (IONM) technology, the strategy of low dose of muscle relaxant, intubation of different endotracheal tubes and electrical stimulation on vocal cord are applied. Its still unknown if these performances would affect patients\u2019 postoperative recovery in thyroid surgery patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>82 patients were randomly assigned to the neuromonitoring group (NEURO Group) and the control group (CON Group). In the CON Group, rocuronium (0.6 mg \/ kg) was given for intubation and additional dose was injected if needed, while in the NEURO Group, only rocuronium (0.3 mg \/ kg) was given when induction. The primary outcome is the QoR-40 scores on postoperative day 1 (POD1) and postoperative day 3 (POD3). Other parameters, such as postoperative nausea or vomiting (PONV) and medical cost were also recorded.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>One subject in each group was excluded, leaving 80 for analysis. In the NEURO Group, the global QoR-40 score, emotional state, physical comfort, physical independence and pain were significantly lower both on POD1 and POD3 (<jats:italic>P<\/jats:italic>&lt;0.05). Patients in the NEURO Group had a higher incidence of PONV (<jats:italic>P<\/jats:italic>&lt;0.05) and medical expense (<jats:italic>P<\/jats:italic>&lt;0.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>After thyroidectomy, the patients using IONM suffer worse quality of recovery, more risk of PONV and increased medical expense.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0292036","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T17:23:34Z","timestamp":1695749014000},"page":"e0292036","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of intraoperative neuromonitoring (IONM) technology on early recovery quality in patients after thyroid surgery: A randomized controlled trial"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6577-6462","authenticated-orcid":true,"given":"Haocong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7981-3068","authenticated-orcid":true,"given":"Zhijun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"pone.0292036.ref001","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.2147\/TCRM.S281572","article-title":"Development and Validation of the Chinese Version of the Quality of Recovery-40 Questionnaire","volume":"16","author":"C Yeyang","year":"2020","journal-title":"Ther Clin Risk Manag"},{"key":"pone.0292036.ref002","doi-asserted-by":"crossref","first-page":"110685","DOI":"10.1016\/j.jclinane.2022.110685","article-title":"Quality of recovery in the perioperative setting: A narrative review","volume":"78","author":"Erica W","year":"2022","journal-title":"J Clin Anesth"},{"key":"pone.0292036.ref003","doi-asserted-by":"crossref","first-page":"109651","DOI":"10.1016\/j.jclinane.2019.109651","article-title":"Ultrasound-guided bilateral superficial cervical plexus blocks enhance the quality of recovery in patients undergoing thyroid cancer surgery: A randomized controlled trial","volume":"61","author":"Y Yusheng","year":"2020","journal-title":"J Clin Anesth"},{"issue":"1","key":"pone.0292036.ref004","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4097\/kja.19352","article-title":"The effect of the type of anesthesia on the quality of postoperative recovery after orthopedic forearm surgery","volume":"73","author":"RD A","year":"2020","journal-title":"Korean J Anesthesiol"},{"issue":"1","key":"pone.0292036.ref005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s12020-020-02207-6","article-title":"Thyroid cancer: incidence and mortality trends in China","volume":"68","author":"W Junyi","year":"2020","journal-title":"Endocrine"},{"key":"pone.0292036.ref006","doi-asserted-by":"crossref","first-page":"676144","DOI":"10.3389\/fendo.2021.676144","article-title":"Prevalence of Thyroid Nodules in China: A Health Examination Cohort-Based Study","volume":"12","author":"L Yunhai","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"9","key":"pone.0292036.ref007","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1111\/ans.16166","article-title":"Investigation of recurrent laryngeal palsy rates for potential associations during thyroidectomy","volume":"90","author":"M Alayne","year":"2020","journal-title":"ANZ J Surg"},{"issue":"2","key":"pone.0292036.ref008","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/ALN.0000000000002960","article-title":"Artificial Intelligence in Anesthesiology: Current Techniques, Clinical Applications, and Limitations","volume":"132","author":"Daniel A H","year":"2020","journal-title":"Anesthesiology"},{"issue":"1","key":"pone.0292036.ref009","first-page":"72","article-title":"Benefit of general anesthesia monitored by bispectral index compared with monitoring guided only by clinical parameters. Systematic review and meta-analysis","volume":"67","author":"Carlos RD O","year":"2017","journal-title":"Braz J Anesthesiol"},{"issue":"2","key":"pone.0292036.ref010","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3390\/jcm11020392","article-title":"Proactive Management of Intraoperative Hypotension Reduces Biomarkers of Organ Injury and Oxidative Stress during Elective Non-Cardiac Surgery: A Pilot Randomized Controlled Trial","volume":"11","author":"M Paolo","year":"2022","journal-title":"J Clin Med"},{"issue":"1","key":"pone.0292036.ref011","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1089\/lap.2020.0293","article-title":"Intraoperative Neuromonitoring in Thyroid and Parathyroid Surgery","volume":"31","author":"Yongman Z","year":"2021","journal-title":"J Laparoendosc Adv Surg Tech A"},{"issue":"1","key":"pone.0292036.ref012","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1186\/s12871-020-01190-9","article-title":"Comparison of the impact of propofol versus sevoflurane on early postoperative recovery in living donors after laparoscopic donor nephrectomy: a prospective randomized controlled study","volume":"20","author":"H Sangbin","year":"2020","journal-title":"BMC Anesthesiology"},{"issue":"1","key":"pone.0292036.ref013","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1186\/s12871-022-01768-5","article-title":"Effects of ultrasound-guided erector spinae plane block with dexmedetomidine combined with ropivacaine of the same dose and different concentrations on analgesic effect and rehabilitation quality of patients undergoing thoracoscopic wedge resection of the lung: a prospective, randomized, controlled trial","volume":"22","author":"Chunfang J","year":"2022","journal-title":"BMC Anesthesiology"},{"issue":"4","key":"pone.0292036.ref014","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/ACO.0000000000000612","article-title":"Measuring quality of recovery in perioperative clinical trials","volume":"31","author":"SM Paul","year":"2018","journal-title":"Curr Opin Anaesthesiology"},{"issue":"1","key":"pone.0292036.ref015","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/s12871-022-01760-z","article-title":"The quality of recovery after erector spinae plane block in patients undergoing breast surgery: a randomized controlled trial","volume":"22","author":"W Marcin","year":"2022","journal-title":"BMC Anesthesiology"},{"issue":"1","key":"pone.0292036.ref016","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/s12871-022-01770-x","article-title":"Quality of recovery in patients administered remimazolam versus those administered an inhalant agent for the maintenance of general anesthesia: a randomized control trial","volume":"22","author":"Seung W S","year":"2022","journal-title":"BMC Anesthesiology"},{"issue":"3","key":"pone.0292036.ref017","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1213\/ANE.0000000000002797","article-title":"Intravenously administered lidocaine and magnesium during thyroid surgery in female patients for better quality of recovery after anesthesia","volume":"127","author":"HK Myoung","year":"2018","journal-title":"Anesth Analg"},{"issue":"9","key":"pone.0292036.ref018","first-page":"1","article-title":"Maintaining optimal surgical condition with low insufflation pressures is possible with deep neuromuscular blockade during laparoscopic colorectal surgery","volume":"95","author":"H K Myoung","year":"2016","journal-title":"Medicine"},{"issue":"4","key":"pone.0292036.ref019","first-page":"1090","article-title":"Effects of depth of neuromuscular block on surgical conditions during laparoscopic colorectal surgery: a randomized controlled trial","volume":"73","author":"B. WK","year":"2018","journal-title":"Anasethesia"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0292036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T17:24:27Z","timestamp":1695749067000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0292036"}},"subtitle":[],"editor":[{"given":"Luigi","family":"La Via","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":19,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2023,9,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0292036","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]}}}