{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:05:23Z","timestamp":1778097923647,"version":"3.51.4"},"reference-count":16,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Lumbosacral radicular syndrome (LRS) is probably the most frequent neuropathic pain syndrome, exaggerating medical and economy burden on developing countries, such as Vietnam. As a result, the urgence to find an approach which is both affordable and effective always puts great demand on medical researchers.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>Evaluate the effectiveness of transforaminal pulsed radiofrequency (PRF) stimulation on the dorsal root ganglion (DRG) and epidural steroid injection (ESI) in management of chronic lumbosacral radiculopathy.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Seventy-six patients with chronic radicular pain were performed transforaminal PRF + ESI by neurosurgeons. Demographic characteristics and surgical outcomes were recorded on admission, pre-procedural and post-procedural for 1-month, 3-month, 6-month and 12-month follow-up. Primary outcome was measured by using Visual Analogue Scale (VAS), Oswestry disability index (ODI) and Straight Leg Raising Test (SLRT). Secondary outcome was subjectively collected based on short assessment of patients\u2019 satisfaction (SAPS).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>Patients who received transforaminal PRF and ESI showed significant improvements on all three evaluation tools (VAS, ODI, SLRT), compared to that before treatment (p&lt;0.001). Pain relief was achievable and long-lasting, which met patients\u2019 expectation. No significant complications were observed for 12 months follow-up.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Transforaminal PRF combined with ESI in management of lumbosacral radiculopathy should be a good method of choice for its effectiveness and safety in management of pain.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0292042","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T17:30:36Z","timestamp":1712251836000},"page":"e0292042","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transforaminal pulsed radiofrequency and epidural steroid injection on chronic lumbar radiculopathy: A prospective observational study from a tertiary care hospital in Vietnam"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4702-7214","authenticated-orcid":true,"given":"Viet-Thang","family":"Le","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phuoc Trong","family":"Do","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vu Duc","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6978-0293","authenticated-orcid":true,"given":"Luan Trung","family":"Nguyen Dao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"issue":"1","key":"pone.0292042.ref001","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/j.pain.0000000000001390","article-title":"The IASP classification of chronic pain for ICD-11: chronic primary pain","volume":"160","author":"M Nicholas","year":"2019","journal-title":"Pain"},{"issue":"36","key":"pone.0292042.ref002","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.15585\/mmwr.mm6736a2","article-title":"Prevalence of chronic pain and high-impact chronic pain among adults\u2014United States, 2016","volume":"67","author":"J Dahlhamer","year":"2018","journal-title":"MMWR Morbidity and mortality weekly report"},{"issue":"3","key":"pone.0292042.ref003","doi-asserted-by":"crossref","first-page":"200","DOI":"10.12701\/jyms.2022.00101","article-title":"The mechanism of action of pulsed radiofrequency in reducing pain: a narrative review","volume":"39","author":"D Park","year":"2022","journal-title":"Journal of Yeungnam medical science"},{"issue":"11","key":"pone.0292042.ref004","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0003-9993(98)90228-3","article-title":"Fluoroscopic transforaminal lumbar epidural steroids: an outcome study","volume":"79","author":"GE Lutz","year":"1998","journal-title":"Archives of physical medicine and rehabilitation"},{"key":"pone.0292042.ref005","doi-asserted-by":"crossref","first-page":"683298","DOI":"10.3389\/fnins.2021.683298","article-title":"Clinical outcome of pulsed-Radiofrequency combined with transforaminaleEpidural steroid injection for lumbosacral radicular pain caused by distinct etiology","volume":"15","author":"L Yang","year":"2021","journal-title":"Frontiers in neuroscience"},{"key":"pone.0292042.ref006","first-page":"559","volume-title":"Practice Guidelines for Spinal Diagnostic and Treatment Procedures","author":"ISI Society","year":"2013","edition":"2"},{"issue":"3","key":"pone.0292042.ref007","first-page":"e16369","article-title":"Caudal epidural of pulsed radiofrequency in post herpetic neuralgia (PHN); Report of three cases","volume":"4","author":"O. 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