{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T10:43:50Z","timestamp":1763117030731,"version":"3.37.3"},"reference-count":47,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","award":["2021029"],"award-info":[{"award-number":["2021029"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"\nIntroduction<\/jats:title>\nSevere acute respiratory syndrome coronavirus 2, (SARS-CoV-2,) caused an influx of patients with acute disease characterized by a variety of symptoms termed COVID-19 disease, with some patients going on to develop post-acute COVID-19 syndrome. Individual factors like sex or coping styles are associated with a person\u2019s disease experience and quality of life. Individual differences in coping styles used to manage COVID-19 related stress correlate with physical and mental health outcomes. Our study sought to understand the relationship between COVID-19 symptoms, severity of acute disease, and coping profiles.<\/jats:p>\n<\/jats:sec>\n\nMethods<\/jats:title>\nAn online survey to assess symptoms, functional status, and recovery in a large group of patients was nationally distributed online. The survey asked about symptoms, course of illness, and included the Brief-COPE and the adapted Social Relationship Inventory. We used descriptive and cluster analyses to characterize patterns of survey responses.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\n976 patients were included in the analysis. The most common symptoms reported by the patients were fatigue (72%), cough (71%), body aches\/joint pain (66%), headache (62%), and fever\/chills (62%). 284 participants reported PACS. We described three different coping profiles: outward, inward, and dynamic copers.<\/jats:p>\n<\/jats:sec>\n\nDiscussion<\/jats:title>\nFatigue, cough, and body aches\/joint pains were the most frequently reported symptoms. PACS patients were sicker, more likely to have been hospitalized. Of the three coping profiles, outward copers were more likely to be admitted to the hospital and had the healthiest coping strategies. Dynamic copers activated several coping strategies both positive and negative; they were also younger and more likely to report PACS.<\/jats:p>\n<\/jats:sec>\n\nConclusion<\/jats:title>\nCough, fatigue, and body aches\/joint pain are common and most important to patients with acute COVID-19, while shortness of breath defined the experience for patients with PACS. Of the three coping profiles, dynamic copers were more likely to report PACS. Additional investigations into coping profiles in general, and the experience of COVID-19 and PACS is needed.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0294201","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T18:34:50Z","timestamp":1700505290000},"page":"e0294201","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patient experiences with SARS-CoV-2: Associations between patient experience of disease and coping profiles"],"prefix":"10.1371","volume":"18","author":[{"given":"Kathryn W.","family":"Hendrickson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramona O.","family":"Hopkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle L.","family":"Groat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie C.","family":"Stokes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona M.","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorie M.","family":"Butler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3838-2679","authenticated-orcid":true,"given":"Eliotte L.","family":"Hirshberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"issue":"5","key":"pone.0294201.ref001","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1473-3099(20)30120-1","article-title":"An interactive web-based dashboard to track COVID-19 in real time","volume":"20","author":"E. 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Han","year":"2022","journal-title":"Pathogens"},{"issue":"1","key":"pone.0294201.ref008","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13256-023-03800-9","article-title":"Management, control, and decision making in unexpected recurrent venous thromboembolism in COVID-19: a case report","volume":"17","author":"R Zolfaghari Emameh","year":"2023","journal-title":"J Med Case Rep"},{"issue":"4","key":"pone.0294201.ref009","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1016\/S1473-3099(21)00703-9","article-title":"A clinical case definition of post-COVID-19 condition by a Delphi consensus","volume":"22","author":"J.B. Soriano","year":"2022","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"pone.0294201.ref010","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s12916-021-02222-y","article-title":"Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development","volume":"20","author":"D. 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