{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:21:40Z","timestamp":1747196500607,"version":"3.40.5"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T00:00:00Z","timestamp":1702512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Tissue extraction plays a crucial role in various medical disciplines, with aspiration catheters serving as the prevailing method. Unfortunately, these catheters face limitations such as clogging and dependence on tissue properties and device dimensions. Therefore, there is a pressing need for an improved tissue extraction device that enables efficient and reliable tissue removal during Minimally Invasive Surgery (MIS).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>In this study, we present a novel tissue transport system that utilizes a cylindrical conveyor belt mechanism for reliable tissue transportation. We conducted experiments using a proof-of-principle prototype to explore the influence of tissue elasticity, rotational velocity, instrument orientation, and tissue shape on the transportation rate, efficiency, and reliability. Tissue phantoms with gelatine concentrations of 3, 9, and 12 wt% were employed to simulate a range of Young\u2019s moduli from 1 to 110 kPa.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The mean transportation rates for these phantoms were 7.75\u00b10.48, 8.43\u00b11.50, and 8.90\u00b10.56 g\/min, respectively. Notably, all phantoms were transported successfully. The perfect reliability exhibited underscores the potential of our instrument as an alternative to aspiration catheters. CONCLUSION: This research presents a significant step forward in the field of tissue extraction, offering a promising approach for MIS with enhanced efficiency and reliability.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0295585","type":"journal-article","created":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T18:38:01Z","timestamp":1702579081000},"page":"e0295585","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advancing minimally invasive surgery: A cutting-edge cable-actuated conveying mechanism for reliable tissue transportation"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2370-0013","authenticated-orcid":true,"given":"Vera Gesina","family":"Kortman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinte","family":"Verberne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovana","family":"Jovanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aim\u00e9e","family":"Sakes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,12,14]]},"reference":[{"issue":"9","key":"pone.0295585.ref001","first-page":"455","article-title":"Extraction of challenging intracoronary thrombi: multi-device strategies using guide catheters, distal vascular protection devices and aspiration catheters","volume":"20","author":"S Pornratanarangsi","year":"2008","journal-title":"The Journal of Invasive Cardiology"},{"issue":"2","key":"pone.0295585.ref002","first-page":"73","article-title":"Hysteroscopic morcellation for treating intrauterine pathology.","volume":"4","author":"S Cohen","year":"2011","journal-title":"Reviews in Obstetrics & Gynecology."},{"issue":"2","key":"pone.0295585.ref003","doi-asserted-by":"crossref","first-page":"121","DOI":"10.5853\/jos.2017.00752","article-title":"Thrombectomy in Acute Ischemic Stroke: Challenges to Procedural Success.","volume":"19","author":"J Yoo A","year":"2017","journal-title":"Journal of Stroke"},{"issue":"5","key":"pone.0295585.ref004","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/CCM.0000000000005819","article-title":"Real-Time Ultrasound Guidance as Compared With Landmark Technique for Subclavian Central Venous Cannulation: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.","volume":"51","author":"M Zawadka","year":"2023","journal-title":"Critical Care Medicine."},{"issue":"3","key":"pone.0295585.ref005","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1245\/ASO.2004.04.021","article-title":"Minimally Invasive Surgery in Pediatric Cancer Patients","volume":"11","author":"W Spurbeck W","year":"2004","journal-title":"Annals of Surgical Oncology"},{"issue":"4","key":"pone.0295585.ref006","doi-asserted-by":"crossref","first-page":"e2106","DOI":"10.1002\/rcs.2106","article-title":"Use of the transoral robotic surgery to treat patients with recurrent lingual tonsillitis","volume":"16","author":"M Di Luca","year":"2020","journal-title":"The International Journal of Medical Robotics and Computer Assisted Surgery"},{"key":"pone.0295585.ref007","volume":"8","author":"A Sakes","year":"2020","journal-title":"Development of a Novel Wasp-Inspired Friction-Based Tissue Transportation Device, Frontiers in Bioengineering and Biotechnology."},{"key":"pone.0295585.ref008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.phmed.2016.11.001","article-title":"Suction force-suction distance relation during aspiration thrombectomy for ischemic stroke: A computational fluid dynamics study","volume":"3","author":"Y Shi","year":"2017","journal-title":"Physics in Medicine"},{"issue":"3","key":"pone.0295585.ref009","first-page":"257","article-title":"Influence of Thrombus Composition on Thrombectomy: ADAPT vs. Balloon Guide Catheter and Stent Retriever in a Flow Model. 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