{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T06:42:39Z","timestamp":1792564959934,"version":"4.5.0"},"reference-count":65,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM103451"],"award-info":[{"award-number":["P20GM103451"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017215","name":"Health Sciences Center, University of New Mexico","doi-asserted-by":"publisher","award":["T32A1007"],"award-info":[{"award-number":["T32A1007"]}],"id":[{"id":"10.13039\/100017215","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    Orthohantaviruses are diverse zoonotic RNA viruses. Small mammals, such as mice and rats are common chronic, asymptomatic hosts that transmit the virus through their feces and urine. In North America, hantavirus infection primarily causes hantavirus cardiopulmonary syndrome (HCPS), which has a mortality rate of nearly 36%. In the United States of America, New Mexico (NM) is leading the nation in the number of HCPS-reported cases (N = 129). However, no reported cases of HCPS have occurred within eastern NM. In this study, we assessed the prevalence of Sin Nombre virus (SNV) in rodent assemblages across eastern NM, using RT-qPCR. We screened for potential rodent hosts in the region, as well as identified areas that may pose significant infection risk to humans. We captured and collected blood and lung tissues from 738 rodents belonging to 23 species. 167 individuals from 16 different species were positive for SNV RNA by RT-qPCR, including 6 species unreported in the literature:\n                    <jats:italic>Onychomys leucogaster<\/jats:italic>\n                    (Northern grasshopper mouse),\n                    <jats:italic>Dipodomys merriami<\/jats:italic>\n                    (Merriam\u2019s kangaroo rat),\n                    <jats:italic>Dipodomys ordii<\/jats:italic>\n                    (Ord\u2019s kangaroo rat),\n                    <jats:italic>Dipodomys spectabilis<\/jats:italic>\n                    (Banner-tailed kangaroo rat),\n                    <jats:italic>Perognathus flavus<\/jats:italic>\n                    (Silky pocket mouse), and\n                    <jats:italic>Chaetodipus hispidus<\/jats:italic>\n                    (Hispid pocket mouse). The infection rates did not differ between sexes or rodent families (i.e., Cricetidae vs. Heteromyidae). Generalized linear model showed that disturbed habitat types positively influenced the prevalence of SNV at sites of survey. Overall, the results of this study indicate that many rodent species in east New Mexico have the potential to maintain SNV in the environment, but further research is needed to assess species specific infectivity mechanisms and potential risk to humans.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0296718","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:31:00Z","timestamp":1705584660000},"page":"e0296718","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Distribution and prevalence of Sin Nombre hantavirus in rodent species in eastern New Mexico"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4636-5752","authenticated-orcid":true,"given":"Jaecy 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