{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:33:17Z","timestamp":1792189997169,"version":"4.4.0"},"reference-count":59,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2020\/37\/B\/HS6\/04196"],"award-info":[{"award-number":["2020\/37\/B\/HS6\/04196"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    The purpose of this study was to reproduce the previously observed spatial summation of pain effect (SSp) using non-laboratory procedures and commercial equipment. An additional aim was to explore the association between expectations and SSp. The Cold Pressor Task (CPT) was used to induce SSp. Healthy participants (N = 68) immersed their non-dominant hands (divided into 5 segments) into cold water (CPT). Two conditions were used 1) gradual hand immersion (ascending condition) and 2) gradual hand withdrawal (descending condition). Pain intensity was measured on a Visual Analogue Scale (VAS). Psychological factors, such as the participants\u2019 expectations of pain intensity were also measured on a VAS. Results showed significant SSp (\u03c7\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sub>(4)<\/jats:sub>\n                    = 116.90,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001), reproduced with non-laboratory equipment in a home-based set-up. Furthermore, two novel findings were observed: i) there was a significant correlation between expectations and perceived pain, indicating a link between pain expectations and SSp, ii) spatial summation increased with the increase in duration exposure to the noxious stimulus (Wald \u03c7\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sub>(8)<\/jats:sub>\n                    = 80.80,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). This study suggests that SSp is associated with pain expectations and can be formed by a mixture of excitatory and inhibitory mechanisms potentially driven by temporal characteristics of neural excitation. Moreover, this study proposes a new feasible way to induce SSp using a home-based set-up.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0297067","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T13:35:43Z","timestamp":1706794543000},"page":"e0297067","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Spatial summation of pain is associated with pain expectations: Results from a home-based paradigm"],"prefix":"10.1371","volume":"19","author":[{"given":"Jakub","family":"Nastaj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-6906","authenticated-orcid":true,"given":"Jacek","family":"Skalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6975-2644","authenticated-orcid":true,"given":"Aleksandra","family":"Budzisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor M.","family":"Szikszay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylwia","family":"Swoboda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weronika","family":"Kowalska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Nowak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edyta","family":"Zbroja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Kruszyna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Jakubi\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominika","family":"Grygny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romuald","family":"Polczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Ma\u0142ecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Luedtke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8941-8355","authenticated-orcid":true,"given":"Wac\u0142aw M.","family":"Adamczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"issue":"6","key":"pone.0297067.ref001","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1097\/j.pain.0000000000002186","article-title":"Nonlinear increase of pain in distance-based and area-based spatial summation","volume":"162","author":"WM Adamczyk","year":"2021","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref002","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.neulet.2006.03.032","article-title":"Endogenous pain inhibitory systems activated by spatial summation are opioid-mediated","volume":"401","author":"N Julien","year":"2006","journal-title":"Neurosci Lett"},{"issue":"3","key":"pone.0297067.ref003","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0304-3959(01)00399-2","article-title":"Spatial summation for pain perception: interaction of inhibitory and excitatory mechanisms","volume":"95","author":"S Marchand","year":"2002","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref004","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.pain.2003.09.010","article-title":"Spatial summation of pressure pain: effect of body region","volume":"106","author":"R Defrin","year":"2003","journal-title":"Pain"},{"issue":"2","key":"pone.0297067.ref005","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/135578501012006192-1","article-title":"Spatial summation of heat pain in males and females","volume":"18","author":"Lautenbacher","year":"2001","journal-title":"Somatosens Mot Res"},{"issue":"1","key":"pone.0297067.ref006","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0304-3959(96)02991-0","article-title":"Spatial summation of heat pain: a reassessment","volume":"66","author":"R Defrin","year":"1996","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref007","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1097\/j.pain.0000000000002069","article-title":"Not as \u201cblurred\u201d as expected? Acuity and spatial summation in the pain system","volume":"162","author":"WM Adamczyk","year":"2021","journal-title":"Pain"},{"issue":"6","key":"pone.0297067.ref008","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1152\/jn.91350.2008","article-title":"Filling-In, Spatial Summation, and Radiation of Pain: Evidence for a Neural Population Code in the Nociceptive System","volume":"102","author":"AS Quevedo","year":"2009","journal-title":"J Neurophysiol"},{"issue":"12","key":"pone.0297067.ref009","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1016\/j.pain.2011.08.017","article-title":"Spatial summation and spatial discrimination of cold pain: Effect of spatial configuration and skin type","volume":"152","author":"R Defrin","year":"2011","journal-title":"Pain"},{"issue":"1","key":"pone.0297067.ref010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.pain.2006.06.026","article-title":"Spatial summation and spatial discrimination of pain sensation","volume":"126","author":"R Defrin","year":"2006","journal-title":"Pain"},{"issue":"6","key":"pone.0297067.ref011","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1152\/jn.1989.62.6.1270","article-title":"Spatial summation of heat-induced pain: influence of stimulus area and spatial separation of stimuli on perceived pain sensation intensity and unpleasantness","volume":"62","author":"DD Price","year":"1989","journal-title":"J Neurophysiol"},{"issue":"6","key":"pone.0297067.ref012","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1097\/j.pain.0000000000000876","article-title":"Lateral inhibition during nociceptive processing","volume":"158","author":"AS Quevedo","year":"2017","journal-title":"Pain"},{"issue":"3962","key":"pone.0297067.ref013","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1126\/science.170.3962.1043","article-title":"Neural Events and the Psychophysical Law: Power functions like those that govern subjective magnitude show themselves in neurelectric effects","volume":"170","author":"SS Stevens","year":"1970","journal-title":"Science"},{"issue":"1","key":"pone.0297067.ref014","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1038\/s41467-022-31039-3","article-title":"Dissociation between individual differences in self-reported pain intensity and underlying fMRI brain activation","volume":"13","author":"ME Hoeppli","year":"2022","journal-title":"Nat Commun"},{"issue":"2","key":"pone.0297067.ref015","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/00029157.2000.10404266","article-title":"Hypnosis and Distraction Differ in Their Effects on Cold Pressor Pain","volume":"43","author":"R Freeman","year":"2000","journal-title":"Am J Clin Hypn"},{"issue":"2","key":"pone.0297067.ref016","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0304-3959(89)90010-9","article-title":"Analgesic effects of different frequencies of transcutaneous electrical nerve stimulation on cold-induced pain in normal subjects","volume":"39","author":"MI Johnson","year":"1989","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref017","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0304-3959(01)00427-4","article-title":"Gender, coping and the perception of pain","volume":"97","author":"E Keogh","year":"2002","journal-title":"Pain"},{"issue":"1\u20133","key":"pone.0297067.ref018","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.neulet.2003.12.060","article-title":"Spatial integration of cold pressor pain sensation in humans","volume":"361","author":"IK Martikainen","year":"2004","journal-title":"Neurosci Lett"},{"issue":"2","key":"pone.0297067.ref019","doi-asserted-by":"crossref","first-page":"401","DOI":"10.2466\/pms.1977.44.2.401","article-title":"Several Variables of Importance in the Use of the Cold Pressor as a Noxious Stimulus in Behavioral Research","volume":"44","author":"TB Westcott","year":"1977","journal-title":"Percept Mot Skills"},{"issue":"5","key":"pone.0297067.ref020","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1172\/JCI101245","article-title":"STUDIES ON PAIN. OBSERVATIONS ON PAIN DUE TO LOCAL COOLING AND ON FACTORS INVOLVED IN THE \u201cCOLD PRESSOR\u201d EFFECT","volume":"20","author":"S Wolf","year":"1941","journal-title":"J Clin Invest"},{"key":"pone.0297067.ref021","article-title":"Spatial tuning in nociceptive processing is driven by attention [Internet]","author":"WM Adamczyk","year":"2022","journal-title":"Neuroscience"},{"issue":"1","key":"pone.0297067.ref022","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.pain.2004.12.032","article-title":"Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition","volume":"114","author":"N Julien","year":"2005","journal-title":"Pain"},{"key":"pone.0297067.ref023","first-page":"1","article-title":"Nielaboratoryjna adaptacja badania przestrzennego sumowania b\u00f3lu w dobie pandemii COVID-19","volume":"21","author":"J Skalski","year":"2021","journal-title":"B\u00d3L"},{"issue":"2","key":"pone.0297067.ref024","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1113\/jphysiol.1996.sp021789","article-title":"C-polymodal nociceptors activated by noxious low temperature in human skin","volume":"497","author":"M Campero","year":"1996","journal-title":"J Physiol"},{"issue":"5","key":"pone.0297067.ref025","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/brain\/awab048","article-title":"Studying human nociceptors: from fundamentals to clinic","volume":"144","author":"SJ Middleton","year":"2021","journal-title":"Brain"},{"issue":"6876","key":"pone.0297067.ref026","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/nature719","article-title":"Identification of a cold receptor reveals a general role for TRP channels in thermosensation","volume":"416","author":"DD McKemy","year":"2002","journal-title":"Nature"},{"key":"pone.0297067.ref027","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jtherbio.2019.06.010","article-title":"Skin TRPA1 ion channel participates in thermoregulatory response to cold. Comparison with the effect of TRPM8","volume":"84","author":"TV Kozyreva","year":"2019","journal-title":"J Therm Biol"},{"issue":"4","key":"pone.0297067.ref028","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jpain.2005.01.349","article-title":"Guidelines for the cold pressor task as an experimental pain stimulus for use with children","volume":"6","author":"C Vonbaeyer","year":"2005","journal-title":"J Pain"},{"issue":"2","key":"pone.0297067.ref029","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.neulet.2012.03.039","article-title":"How expectations shape pain","volume":"520","author":"LY Atlas","year":"2012","journal-title":"Neurosci Lett"},{"issue":"1","key":"pone.0297067.ref030","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/j.pain.0000000000001272","article-title":"How expectations influence pain","volume":"159","author":"HL Fields","year":"2018","journal-title":"Pain"},{"issue":"39","key":"pone.0297067.ref031","doi-asserted-by":"crossref","first-page":"12964","DOI":"10.1523\/JNEUROSCI.0057-10.2010","article-title":"Brain Mediators of Predictive Cue Effects on Perceived Pain","volume":"30","author":"LY Atlas","year":"2010","journal-title":"J Neurosci"},{"issue":"36","key":"pone.0297067.ref032","doi-asserted-by":"crossref","first-page":"12950","DOI":"10.1073\/pnas.0408576102","article-title":"The subjective experience of pain: Where expectations become reality","volume":"102","author":"T Koyama","year":"2005","journal-title":"Proc Natl Acad Sci"},{"issue":"2","key":"pone.0297067.ref033","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s10827-021-00780-x","article-title":"Predictive coding models for pain perception","volume":"49","author":"Y Song","year":"2021","journal-title":"J Comput Neurosci"},{"issue":"6","key":"pone.0297067.ref034","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/j.neuron.2014.02.042","article-title":"Placebo Analgesia: A Predictive Coding Perspective","volume":"81","author":"C B\u00fcchel","year":"2014","journal-title":"Neuron"},{"issue":"1","key":"pone.0297067.ref035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/h0076157","article-title":"Consequences of prejudice against the null hypothesis","volume":"82","author":"AG Greenwald","year":"1975","journal-title":"Psychol Bull"},{"issue":"5","key":"pone.0297067.ref036","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/dmcn.14054","article-title":"Practical tools and strategies for researchers to increase replicability","volume":"61","author":"MB Nuijten","year":"2019","journal-title":"Dev Med Child Neurol"},{"issue":"4","key":"pone.0297067.ref037","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/16506070600898512","article-title":"Differences in High and Low Anxiety Sensitive Women\u2019s Responses to a Laboratory\u2010Based Cold Pressor Task","volume":"35","author":"LS Uman","year":"2006","journal-title":"Cogn Behav Ther"},{"issue":"1","key":"pone.0297067.ref038","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1155\/2014\/213950","article-title":"Laboratory Personnel Gender and Cold Pressor Apparatus Affect Subjective Pain Reports","volume":"19","author":"JM Vigil","year":"2014","journal-title":"Pain Res Manag"},{"key":"pone.0297067.ref039","doi-asserted-by":"crossref","first-page":"100128","DOI":"10.1016\/j.pdisas.2020.100128","article-title":"Impact of COVID-19 restrictions on the research environment and motivation of researchers in Japan","volume":"8","author":"Y Miki","year":"2020","journal-title":"Prog Disaster Sci"},{"key":"pone.0297067.ref040","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ijsu.2020.12.008","article-title":"Impact of the coronavirus (COVID-19) pandemic on scientific research and implications for clinical academic training\u2013A review","volume":"86","author":"C Sohrabi","year":"2021","journal-title":"Int J Surg"},{"issue":"4","key":"pone.0297067.ref041","first-page":"373","article-title":"Ethical principles for medical research involving human subjects","volume":"79","author":"World Medical Association. World Medical Association Declaration of Helsinki","year":"2001","journal-title":"Bull World Health Organ"},{"issue":"11","key":"pone.0297067.ref042","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1097\/j.pain.0000000000000331","article-title":"Healthy and normal? The need for clear reporting and flexible criteria for defining control participants in quantitative sensory testing studies","volume":"156","author":"RC Coghill","year":"2015","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref043","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/smi.2446","article-title":"Effect of Brief Mindfulness Intervention on Tolerance and Distress of Pain Induced by Cold-Pressor Task: Brief Mindfulness Intervention on Tolerance Pain","volume":"29","author":"X Liu","year":"2013","journal-title":"Stress Health"},{"key":"pone.0297067.ref044","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3389\/fphys.2017.00258","article-title":"Whole-Body Cryotherapy in Athletes: From Therapy to Stimulation. An Updated Review of the Literature","volume":"8","author":"G Lombardi","year":"2017","journal-title":"Front Physiol"},{"issue":"4","key":"pone.0297067.ref045","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1600-0838.1996.tb00090.x","article-title":"Cryotherapy in sports medicine","volume":"6","author":"C Swenson","year":"2007","journal-title":"Scand J Med Sci Sports"},{"issue":"5","key":"pone.0297067.ref046","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1093\/ajcn\/36.5.936","article-title":"A short questionnaire for the measurement of habitual physical activity in epidemiological studies","volume":"36","author":"JA Baecke","year":"1982","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"pone.0297067.ref047","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2478\/v10036-009-0004-7","article-title":"An Analysis of Relations Between a Self-Assessment of Health and Active Life-Style","volume":"13","author":"A Knapik","year":"2009","journal-title":"Med Sport"},{"key":"pone.0297067.ref048","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/7640649","article-title":"The Reliability and Validity of Using Ice to Measure Cold Pain Threshold","volume":"2017","author":"P Tilley","year":"2017","journal-title":"BioMed Res Int"},{"issue":"2","key":"pone.0297067.ref049","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/AJP.0b013e318183cfa4","article-title":"The Deficit of Pain Inhibition in Fibromyalgia Is More Pronounced in Patients With Comorbid Depressive Symptoms","volume":"25","author":"JB de Souza","year":"2009","journal-title":"Clin J Pain"},{"issue":"3","key":"pone.0297067.ref050","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ejpain.2009.05.011","article-title":"Differential physiological effects during tonic painful hand immersion tests using hot and ice water","volume":"14","author":"A Streff","year":"2010","journal-title":"Eur J Pain"},{"issue":"2","key":"pone.0297067.ref051","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0304-3959(94)00270-O","article-title":"Dorsal horn convergent neurones: negative feedback triggered by spatial summation of nociceptive afferents","volume":"62","author":"D Bouhassira","year":"1995","journal-title":"Pain"},{"issue":"3","key":"pone.0297067.ref052","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.neulet.2009.06.089","article-title":"Unmyelinated afferents in human skin and their responsiveness to low temperature","volume":"470","author":"M Campero","year":"2010","journal-title":"Neurosci Lett"},{"issue":"1","key":"pone.0297067.ref053","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1113\/jphysiol.1992.sp019075","article-title":"The role of nociceptors of cutaneous veins in the mediation of cold pain in man","volume":"449","author":"W Klement","year":"1992","journal-title":"J Physiol"},{"issue":"2","key":"pone.0297067.ref054","first-page":"183","article-title":"Spatial summation of thermal pain in human beings","volume":"3","author":"H Machet-Pietropaoli","year":"1979","journal-title":"Sens Processes"},{"issue":"4","key":"pone.0297067.ref055","doi-asserted-by":"crossref","first-page":"e0231697","DOI":"10.1371\/journal.pone.0231697","article-title":"Validity of the cold pressor test and pain sensitivity questionnaire via online self-administration","volume":"15","author":"23andMe Research Team","year":"2020","journal-title":"PLOS ONE"},{"issue":"6312","key":"pone.0297067.ref056","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1126\/science.aaf8934","article-title":"Deconstructing the sensation of pain: The influence of cognitive processes on pain perception","volume":"354","author":"K. Wiech","year":"2016","journal-title":"Science"},{"issue":"1","key":"pone.0297067.ref057","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/ejp.1294","article-title":"General versus pain\u2010specific cognitions: Pain catastrophizing but not optimism influences conditioned pain modulation","volume":"23","author":"J Traxler","year":"2019","journal-title":"Eur J Pain"},{"issue":"4","key":"pone.0297067.ref058","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s12160-016-9775-y","article-title":"Expectancy Effects on Conditioned Pain Modulation Are Not Influenced by Naloxone or Morphine","volume":"50","author":"CR France","year":"2016","journal-title":"Ann Behav Med"},{"key":"pone.0297067.ref059","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2147\/JPR.S33559","article-title":"Expectations of increased and decreased pain explain the effect of conditioned pain modulation in females","author":"E Bj\u00f8rkedal","year":"2012","journal-title":"J Pain Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0297067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T13:37:20Z","timestamp":1706794640000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0297067"}},"subtitle":[],"editor":[{"given":"Tomoyoshi","family":"Komiyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":59,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0297067","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.09.30.510274","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]}}}