{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T22:29:16Z","timestamp":1785709756995,"version":"3.56.0"},"reference-count":56,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["R01MH101269"],"award-info":[{"award-number":["R01MH101269"]}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["U01 CA176726"],"award-info":[{"award-number":["U01 CA176726"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH","award":["u01 HL145386"],"award-info":[{"award-number":["u01 HL145386"]}]},{"name":"NIH","award":["T32 HL098048"],"award-info":[{"award-number":["T32 HL098048"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background and objective<\/jats:title>\n<jats:p>This study examined the potential influence of pre-pandemic psychological resilience on use of approach or avoidant coping styles and strategies to manage stress during the COVID-19 pandemic. We hypothesized that higher resilience would be associated with more approach coping and less avoidant coping.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Design and methods<\/jats:title>\n<jats:p>Longitudinal cohort data were from the Nurses\u2019 Health Study II, including 13,143 female current and former healthcare professionals with pre-pandemic lifetime trauma. Pre-pandemic resilience was assessed between 2018\u20132019 and current coping during the outbreak of the pandemic in the United States (May-August 2020). Multiple linear regression model results identified associations between continuous pre-pandemic resilience scores and use of approach and avoidant coping styles, as well as individual coping strategies, adjusting for relevant covariates.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Greater resilience was associated with higher use of approach coping (\u00df = 0.06, 95% CI 0.05, 0.08) and lower use of avoidant coping styles (\u00df = -0.39, 95% CI -0.41, -0.38). Higher pre-pandemic resilience was also associated with use of eight (distraction [\u00df = -0.18, 95% CI -0.20, -0.16], substance use [\u00df = -0.15, 95% CI -0.17, -0.13], behavioral disengagement [\u00df = -0.29, 95% CI -0.30, -0.27], self-blame [\u00df = -0.44, 95% CI -0.45, -0.42], emotional support (\u00df = 0.03, 95% CI 0.01, 0.05), positive reframing [\u00df = 0.13, 95% CI 0.12, 0.15], humor [\u00df = 0.03, 95% CI 0.01, 0.05] and religion [\u00df = 0.06, 95% CI 0.04, 0.08]) of the nine coping strategies in expected directions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Findings have important implications for intervention or even prevention efforts to support vulnerable groups, such as women with prior trauma histories, during this and other immensely stressful times. Supporting or building psychological resilience following trauma may promote effective coping in times of future stress.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0297169","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T17:23:48Z","timestamp":1715102628000},"page":"e0297169","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prior resilience to trauma &amp; coping during the COVID-19 pandemic"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3680-9405","authenticated-orcid":true,"given":"Arielle A. 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Stressors and Coping","volume":"25","author":"T Mi","year":"2020","journal-title":"AIDS and behavior"},{"key":"pone.0297169.ref018","doi-asserted-by":"crossref","first-page":"567201","DOI":"10.3389\/fpsyg.2020.567201","article-title":"From Resilience to Burnout: Psychological Features of Italian General Practitioners During COVID-19 Emergency","volume":"11","author":"C Di Monte","year":"2020","journal-title":"Frontiers in psychology"},{"issue":"3","key":"pone.0297169.ref019","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/1467-8624.00164","article-title":"The Construct of Resilience: A Critical Evaluation and Guidelines for Future Work","volume":"71","author":"SS Luthar","year":"2000","journal-title":"Child development"},{"issue":"4","key":"pone.0297169.ref020","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1017\/S0954579400005812","article-title":"Resilience and development: Contributions from the study of children who overcome adversity","volume":"2","author":"AS Masten","year":"1990","journal-title":"Development and psychopathology"},{"key":"pone.0297169.ref021","first-page":"181","volume-title":"Psychosocial resilience and protective mechanisms","author":"M. Rutter","year":"1990"},{"issue":"1","key":"pone.0297169.ref022","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1037\/0003-066X.59.1.20","article-title":"Loss, Trauma, and Human Resilience: Have We Underestimated the Human Capacity to Thrive After Extremely Aversive Events?","volume":"59","author":"GA Bonanno","year":"2004","journal-title":"The American psychologist"},{"issue":"2","key":"pone.0297169.ref023","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/da.10113","article-title":"Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC)","volume":"18","author":"KM Connor","year":"2003","journal-title":"Depression and anxiety"},{"issue":"12","key":"pone.0297169.ref024","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1038\/s41380-019-0457-6","article-title":"Genomics and psychological resilience: a research agenda","volume":"24","author":"KW Choi","year":"2019","journal-title":"Molecular psychiatry"},{"key":"pone.0297169.ref025","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.1017\/S0140525X1400082X","article-title":"A conceptual framework for the neurobiological study of resilience","volume":"38","author":"R Kalisch","year":"2015","journal-title":"The Behavioral and brain sciences"},{"issue":"1","key":"pone.0297169.ref026","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1146\/annurev-psych-020122-041854","article-title":"Psychological Resilience: An Affect-Regulation Framework","volume":"74","author":"AS Troy","year":"2023","journal-title":"Annual review of psychology"},{"issue":"1","key":"pone.0297169.ref027","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1196\/annals.1364.020","article-title":"Developmental Epidemiology of PTSD: Self-Regulation as a Central Mechanism","volume":"1071","author":"KC Koenen","year":"2006","journal-title":"Annals of the New York Academy of 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Study","volume":"118","author":"KM Nishimi","year":"2021","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"3","key":"pone.0297169.ref040","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1037\/pas0000486","article-title":"The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5): Development and Initial Psychometric Evaluation in Military Veterans","volume":"30","author":"FW Weathers","year":"2018","journal-title":"Psychological assessment"},{"issue":"2","key":"pone.0297169.ref041","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0749-3797(18)30622-6","article-title":"Screening for Depression in Well Older Adults: Evaluation of a Short Form of the CES-D","volume":"10","author":"EM Andresen","year":"1994","journal-title":"American journal of preventive medicine"},{"issue":"10","key":"pone.0297169.ref042","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"RL Spitzer","year":"2006","journal-title":"Archives of internal medicine"},{"issue":"1","key":"pone.0297169.ref043","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1207\/s15327752jpa4901_13","article-title":"The Satisfaction With Life Scale","volume":"49","author":"E Diener","year":"1985","journal-title":"Journal of personality assessment"},{"issue":"6","key":"pone.0297169.ref044","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1037\/0022-3514.67.6.1063","article-title":"Distinguishing Optimism From Neuroticism (and Trait Anxiety, Self-Mastery, and Self-Esteem): A Reevaluation of the Life Orientation Test","volume":"67","author":"MF Scheier","year":"1994","journal-title":"Journal of personality and social psychology"},{"issue":"4","key":"pone.0297169.ref045","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1037\/0022-3514.69.4.719","article-title":"The structure of psychological well-being revisited","volume":"69","author":"CD Ryff","year":"1995","journal-title":"Journal of personality and social psychology"},{"issue":"9","key":"pone.0297169.ref046","doi-asserted-by":"crossref","first-page":"e011866","DOI":"10.1161\/JAHA.118.011866","article-title":"Psychological Distress and Subsequent Cardiovascular Events in Individuals With Coronary Artery Disease","volume":"8","author":"P Pimple","year":"2019","journal-title":"Journal of the American Heart Association"},{"issue":"12","key":"pone.0297169.ref047","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/spc3.12224","article-title":"Positive Psychological Functioning and the Biology of Health","volume":"9","author":"LD Kubzansky","year":"2015","journal-title":"Social and personality psychology compass"},{"issue":"1","key":"pone.0297169.ref048","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s42761-023-00184-3","article-title":"Introduction to Special Issue: Interventions to Modify Psychological 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