{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T18:02:26Z","timestamp":1782410546889,"version":"3.54.5"},"reference-count":105,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The primary objective of this review was to create a \u2018trustworthy,\u2019 living systematic review and meta-analysis for the application of manual therapy interventions in treating patients with shoulder dysfunction. Included studies were English-language randomized controlled trials published between 1\/1\/2010 and 8\/3\/2023, with searches performed in: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), CINHAL, ProQuest Nursing &amp; Allied Health, EBSCO Medline, and PEDro. The population of focus included adults 18 years and older with musculoskeletal impairments related to shoulder dysfunction. Our primary outcomes included pain and region-specific outcome measures. We excluded trials, including participants having shoulder dysfunction resulting from surgery, radicular pain, instability\/dislocation, fracture, lymphedema, and radiation. Our screening methodology was based upon a previously published \u2018trustworthy\u2019 systematic review protocol. This included the application of our PICOTS criteria in addition to screening for prospective clinical trial registration and following of prospective intent, as well as assessment of PEDro scores, risk-of-bias ratings, GRADE scoring, and examination of confidence in estimated effects. Twenty-six randomized controlled trials met our PICOTS criteria; however, only 15 of these were registered. Only three were registered prospectively. Two of these did not have discussions and conclusions that aligned with their primary outcome. The remaining single study was found to have a high risk-of-bias, meaning the remainder of the protocol could not be employed and that no randomized controlled trials could undergo further assessment or meta-analysis. The results of this systematic review indicate there are no \u2018trustworthy\u2019 randomized controlled trials examining the effectiveness of manual therapy interventions for the treatment of patients with shoulder dysfunction, as defined by the prospectively established methodology. Therefore, these findings signal that creating a \u2018trustworthy,\u2019 living systematic review on this clinically relevant topic is not yet possible due to a lack of \u2018trustworthy\u2019 randomized controlled trials.<\/jats:p>","DOI":"10.1371\/journal.pone.0297234","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T18:32:38Z","timestamp":1705602758000},"page":"e0297234","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is there \u2018trustworthy\u2019 evidence for using manual therapy to treat patients with shoulder dysfunction?: A systematic review"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0217-9572","authenticated-orcid":true,"given":"Daniel W.","family":"Flowers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian 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Ther"},{"key":"pone.0297234.ref010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12998-015-0075-6","article-title":"The effectiveness of manual therapy for the management of musculoskeletal disorders of the upper and lower extremities: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration.","volume":"23","author":"D Southerst","year":"2015","journal-title":"Chiropr Man Ther."},{"issue":"1","key":"pone.0297234.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12998-016-0133-8","article-title":"A systematic review of thrust manipulation for non-surgical shoulder conditions.","volume":"25","author":"AL Minkalis","year":"2017","journal-title":"Chiropr Man Ther"},{"issue":"1","key":"pone.0297234.ref012","first-page":"5","article-title":"A systematic review of thrust manipulation combined with one conservative intervention for rotator cuff and related non-surgical shoulder conditions.","volume":"62","author":"AL Minkalis","year":"2018","journal-title":"J Can Chiropr Assoc"},{"issue":"2","key":"pone.0297234.ref013","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1179\/108331906X99065","article-title":"Exercise and manual therapy for the treatment of impingement syndrome of the shoulder: A systematic review","volume":"11","author":"A Trampas","year":"2006","journal-title":"Phys Ther Rev"},{"issue":"3","key":"pone.0297234.ref014","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/00042752-200305000-00009","article-title":"Therapeutic exercise and orthopedic manual therapy for impingement syndrome: A systematic review.","volume":"13","author":"F Desmeules","year":"2003","journal-title":"Clin J Sport Med"},{"issue":"3","key":"pone.0297234.ref015","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/sae.12009","article-title":"A review of systematic reviews of the effectiveness of conservative interventions for rotator cuff 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shoulder: A systematic review.","volume":"8","author":"R Ferlito","year":"2023","journal-title":"J Funct Morphol Kinesiol"},{"key":"pone.0297234.ref022","first-page":"CD012224","article-title":"Manual therapy and exercise for rotator cuff disease.","volume":"6","author":"MJ Page","year":"2016","journal-title":"Cochrane Database of Systematic Reviews."},{"issue":"9","key":"pone.0297234.ref023","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.jmpt.2010.08.019","article-title":"A systematic review of manipulative therapy for the treatment of shoulder pain","volume":"33","author":"M Pribicevic","year":"2010","journal-title":"J Manipulative Physiol Ther"},{"key":"pone.0297234.ref024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.msksp.2017.10.006","article-title":"Thoracic manual therapy is not more effective than placebo thoracic manual therapy in patients with shoulder dysfunctions: A systematic review with meta-analysis.","volume":"33","author":"P Bizzarri","year":"2018","journal-title":"Musculoskelet Sci Pract"},{"issue":"1","key":"pone.0297234.ref025","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/10669817.2021.1955181","article-title":"Efficacy of mobilization with movement (MWM) for shoulder conditions: A systematic review and meta-analysis.","volume":"30","author":"K Satpute","year":"2022","journal-title":"J Man Manip Ther"},{"issue":"4","key":"pone.0297234.ref026","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1179\/106698109791352076","article-title":"Effectiveness of manual physical therapy for painful shoulder conditions: A systematic review.","volume":"17","author":"J Camarinos","year":"2009","journal-title":"J Man Manip Ther"},{"issue":"5","key":"pone.0297234.ref027","first-page":"e7265","article-title":"The effectiveness of joint mobilization techniques for range of motion in adult patients with primary adhesive capsulitis of the shoulder: A systematic review and 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prospective registration of randomized clinical trials of nonregulated health care interventions","volume":"179","author":"M Azar","year":"2019","journal-title":"JAMA Internal Medicine"},{"issue":"11","key":"pone.0297234.ref031","doi-asserted-by":"crossref","first-page":"542","DOI":"10.2519\/jospt.2021.10491","article-title":"The unknown prevalence of postrandomization bias in 15 physical therapy journals: A methods review","volume":"51","author":"SP Riley","year":"2021","journal-title":"J Orthop Sports Phys Ther"},{"issue":"2","key":"pone.0297234.ref032","doi-asserted-by":"crossref","first-page":"e020037","DOI":"10.1136\/bmjopen-2017-020037","article-title":"Characteristics and publication fate of unregistered and retrospectively registered clinical trials submitted to The BMJ over 4 years.","volume":"8","author":"E Loder","year":"2018","journal-title":"BMJ Open."},{"issue":"5","key":"pone.0297234.ref033","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/10669817.2015.1119372","article-title":"A systematic review of orthopaedic manual therapy randomized clinical trials quality.","volume":"24","author":"SP Riley","year":"2016","journal-title":"J Man Manip Ther"},{"issue":"3","key":"pone.0297234.ref034","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1080\/10669817.2022.2110419","article-title":"Is the quality of systematic reviews influenced by prospective registration: A methods review of systematic musculoskeletal physical therapy reviews.","volume":"31","author":"SP Riley","year":"2023","journal-title":"J Man Manip Ther"},{"key":"pone.0297234.ref035","first-page":"1","article-title":"Protocol for the development of a \u2018trustworthy\u2019 living systematic review and meta analyses of manual therapy interventions to treat neuromusculoskeletal impairments.","author":"SP Riley","year":"2022","journal-title":"J Man Manip Ther"},{"issue":"4","key":"pone.0297234.ref036","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/10669817.2023.2201917","article-title":"Manual therapy for non-radicular cervical spine related impairments: Establishing a \u2018Trustworthy\u2019living systematic review and meta-analysis.","volume":"31","author":"SP Riley","year":"2023","journal-title":"J Man Manip Ther"},{"key":"pone.0297234.ref037","first-page":"1","article-title":"Does manual therapy meaningfully change quantitative sensory testing and patient reported outcome measures in patients with musculoskeletal impairments related to the spine?: A \u2018trustworthy\u2019systematic review and meta-analysis.","author":"SP Riley","year":"2023","journal-title":"J Man Manip Ther"},{"issue":"1","key":"pone.0297234.ref038","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40945-023-00162-9","article-title":"\u201cTrustworthiness,\u201d confidence in estimated effects, and confidently translating research into clinical practice.","volume":"13","author":"SP Riley","year":"2023","journal-title":"Arch Physiother"},{"issue":"4","key":"pone.0297234.ref039","first-page":"216","article-title":"Can\" strong\" recommendations be made for exercise and manual therapy in treating subacromial shoulder pain?","volume":"50","author":"C Littlewood","year":"2020","journal-title":"J Orthop Sports Phys Ther"},{"issue":"4","key":"pone.0297234.ref040","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1080\/10669817.2023.2229610","article-title":"Why do \u2018Trustworthy\u2019 living systematic reviews matter?","volume":"31","author":"SP Riley","year":"2023","journal-title":"J Man Manip Ther"},{"key":"pone.0297234.ref041","unstructured":"Research NIoH. Reviews of methodology University of York, York, UK, YO10 5DD: University of York Centre for Reviews and Dissemination; 2020 [11\/22\/2020]. Available from: https:\/\/www.crd.york.ac.uk\/prospero\/#sub_methodology."},{"key":"pone.0297234.ref042","doi-asserted-by":"crossref","first-page":"n160","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"key":"pone.0297234.ref043","doi-asserted-by":"crossref","DOI":"10.1007\/s11606-011-1961-9","volume-title":"Assessing applicability of medical test studies in systematic reviews.","author":"KE Hartmann","year":"2012"},{"key":"pone.0297234.ref044","volume-title":"International Classification of Functioning disability and Health","author":"WH Organization","year":"2001"},{"key":"pone.0297234.ref045","first-page":"98","article-title":"Experimental development of the graphic rating method","volume":"18","author":"M. Hayes","year":"1921","journal-title":"Psychol Bull"},{"issue":"4","key":"pone.0297234.ref046","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/art.1790040403","article-title":"Development of a shoulder pain and disability index","volume":"4","author":"KE Roach","year":"1991","journal-title":"Arthritis Rheum"},{"issue":"5","key":"pone.0297234.ref047","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1080\/09593985.2018.1453004","article-title":"Reliability and relationship of the fear-avoidance beliefs questionnaire with the shoulder pain and disability index and numeric pain rating scale in patients with shoulder pain","volume":"35","author":"SP Riley","year":"2019","journal-title":"Physiother Theory Pract"},{"issue":"6","key":"pone.0297234.ref048","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/(SICI)1097-0274(199606)29:6<602::AID-AJIM4>3.0.CO;2-L","article-title":"Development of an upper extremity outcome measure: The DASH (disabilities of the arm, shoulder, and head).","volume":"29","author":"PL Hudak","year":"1996","journal-title":"Am J Ind Med."},{"issue":"1","key":"pone.0297234.ref049","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2519\/jospt.2014.4893","article-title":"Minimal clinically important difference of the disabilities of the arm, shoulder and hand outcome measure (DASH) and its shortened version (QuickDASH).","volume":"44","author":"F Franchignoni","year":"2014","journal-title":"J Orthop Sports Phys Ther"},{"issue":"4","key":"pone.0297234.ref050","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0197-2456(89)90005-6","article-title":"Measurement of health status: Ascertaining the minimal clinically important difference.","volume":"10","author":"R Jaeschke","year":"1989","journal-title":"Control Clin Trials"},{"issue":"2","key":"pone.0297234.ref051","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1177\/03635465990270021701","article-title":"Comparison of the single assessment numeric evaluation method and two shoulder rating scales.","volume":"27","author":"GN Williams","year":"1999","journal-title":"Am J Sports Med"},{"key":"pone.0297234.ref052","first-page":"37","volume":"35","author":"R Schwarzer","year":"1995","journal-title":"Generalized self-efficacy scale. J Weinman, S Wright, & M Johnston, Measures in health psychology: A user\u2019s portfolio. Causal and control beliefs."},{"issue":"2","key":"pone.0297234.ref053","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0304-3959(93)90127-B","article-title":"A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability.","volume":"52","author":"G Waddell","year":"1993","journal-title":"Pain"},{"issue":"1\u20132","key":"pone.0297234.ref054","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.pain.2005.05.029","article-title":"Psychometric properties of the TSK-11: a shortened version of the Tampa Scale for Kinesiophobia","volume":"117","author":"SR Woby","year":"2005","journal-title":"Pain"},{"issue":"7","key":"pone.0297234.ref055","doi-asserted-by":"crossref","first-page":"A1","DOI":"10.2519\/jospt.2017.0302","article-title":"Neck pain: Revision 2017.","volume":"47","author":"PR Blanpied","year":"2017","journal-title":"J Orthop Sports Phys Ther"},{"issue":"Supplement C","key":"pone.0297234.ref056","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jclinepi.2016.01.021","article-title":"PRESS peer review of electronic search strategies: 2015 guideline statement.","volume":"75","author":"J McGowan","year":"2016","journal-title":"J Clin Epidemiol."},{"issue":"21","key":"pone.0297234.ref057","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1097\/BRS.0000000000001061","article-title":"2015 updated method guideline for systematic reviews in the Cochrane Back and Neck Group","volume":"40","author":"AD Furlan","year":"2015","journal-title":"Spine"},{"key":"pone.0297234.ref058","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/9780470712184.ch6","article-title":"Searching for studies.","author":"C Lefebvre","year":"2008","journal-title":"Cochrane handbook for systematic reviews of interventions"},{"key":"pone.0297234.ref059","article-title":"RoB 2: A revised tool for assessing risk of bias in randomised trials","volume":"366","author":"JA Sterne","year":"2019","journal-title":"BMJ"},{"key":"pone.0297234.ref060","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12998-016-0126-7","article-title":"Effectiveness of manual therapy for cervical radiculopathy, a review.","volume":"24","author":"EJ Thoomes","year":"2016","journal-title":"Chiropr Man Therap"},{"issue":"4","key":"pone.0297234.ref061","doi-asserted-by":"crossref","first-page":"645","DOI":"10.3233\/BMR-170884","article-title":"The application of the Neurac technique vs. manual therapy in patients during the acute phase of subacromial impingement syndrome: A randomized single-blinded controlled trial.","volume":"33","author":"S-Y Kim","year":"2020","journal-title":"J Back Musculoskelet Rehabil"},{"key":"pone.0297234.ref062","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.jbmt.2020.11.017","article-title":"Comparison between dry needling plus manual therapy with manual therapy alone on pain and function in overhead athletes with scapular dyskinesia: A randomized clinical trial","volume":"26","author":"A Kheradmandi","year":"2021","journal-title":"J Bodyw Mov Ther"},{"issue":"15","key":"pone.0297234.ref063","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.3390\/jcm11154395","article-title":"Real versus sham manual therapy in addition to therapeutic exercise in the treatment of non-specific shoulder pain: A randomized controlled trial","volume":"11","author":"F Naranjo-Cinto","year":"2022","journal-title":"J Clin Med"},{"issue":"1","key":"pone.0297234.ref064","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.math.2013.05.007","article-title":"The addition of cervical unilateral posterior\u2013anterior mobilisation in the treatment of patients with shoulder impingement syndrome: A randomised clinical trial.","volume":"19","author":"C Cook","year":"2014","journal-title":"Man Ther"},{"issue":"4","key":"pone.0297234.ref065","doi-asserted-by":"crossref","first-page":"252","DOI":"10.2519\/jospt.2015.5745","article-title":"The comparative effects of spinal and peripheral thrust manipulation and exercise on pain sensitivity and the relation to clinical outcome: A mechanistic trial using a shoulder pain model","volume":"45","author":"RA Coronado","year":"2015","journal-title":"J Orthop Sports Phys Ther"},{"issue":"1","key":"pone.0297234.ref066","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jcm.2018.10.001","article-title":"Immediate effects of spinal manipulation on shoulder motion range and pain in individuals with shoulder pain: A randomized trial","volume":"18","author":"AC da Silva","year":"2019","journal-title":"J Chiropr Med"},{"issue":"5","key":"pone.0297234.ref067","doi-asserted-by":"crossref","first-page":"jrm00190","DOI":"10.2340\/16501977-2806","article-title":"Guided exercises with or without joint mobilization or no treatment in patients with subacromial pain syndrome: A clinical trial.","volume":"53","author":"A Eliason","year":"2021","journal-title":"J Rehabil Med"},{"issue":"10","key":"pone.0297234.ref068","doi-asserted-by":"crossref","first-page":"716","DOI":"10.2519\/jospt.2019.8484","article-title":"The comparative effects of upper thoracic spine thrust manipulation techniques in individuals with subacromial pain syndrome: A randomized clinical trial","volume":"49","author":"JK Grimes","year":"2019","journal-title":"J Orthop Sports Phys Ther"},{"issue":"9","key":"pone.0297234.ref069","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.jmpt.2016.08.001","article-title":"Immediate effects of mobilization with movement vs sham technique on range of motion, strength, and function in patients with shoulder impingement syndrome: Randomized clinical trial.","volume":"39","author":"JF Guimar\u00e3es","year":"2016","journal-title":"J Manipulative Physiol 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taping in painful shoulders.","volume":"18","author":"P Teys","year":"2013","journal-title":"Man Ther."},{"issue":"2","key":"pone.0297234.ref086","doi-asserted-by":"crossref","first-page":"178","DOI":"10.2522\/ptj.20100111","article-title":"Does passive mobilization of shoulder region joints provide additional benefit over advice and exercise alone for people who have shoulder pain and minimal movement restriction? 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Van Noorden","year":"2023","journal-title":"Nature"},{"key":"pone.0297234.ref089","article-title":"Trials we cannot trust: Investigating their impact on systematic reviews and clinical guidelines in spinal pain.","author":"N O\u2019Connell","year":"2023","journal-title":"J Pain"},{"issue":"6","key":"pone.0297234.ref090","first-page":"792","article-title":"Endocrine response after cervical manipulation and mobilization in people with chronic mechanical neck pain: A randomized controlled trial","volume":"55","author":"A Valera-Calero","year":"2019","journal-title":"Eur J Phys Rehabil Med"},{"key":"pone.0297234.ref091","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.ctim.2019.02.012","article-title":"Short-term effectiveness of the flexion-distraction technique in comparison with high-velocity vertebral manipulation in patients suffering from low-back pain","volume":"44","author":"F Carrasco-Mart\u00ednez","year":"2019","journal-title":"Complement Ther Med"},{"issue":"3","key":"pone.0297234.ref092","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jphys.2020.06.007","article-title":"Directed vertebral manipulation is not better than generic vertebral manipulation in patients with chronic low back pain: A randomised trial","volume":"66","author":"RF de Oliveira","year":"2020","journal-title":"J Physiother"},{"issue":"11","key":"pone.0297234.ref093","doi-asserted-by":"crossref","first-page":"CPG1","DOI":"10.2519\/jospt.2021.0304","article-title":"Interventions for the management of acute and chronic low back pain: Revision 2021: Clinical practice guidelines linked to the international classification of functioning, disability and health from the academy of orthopaedic physical therapy of the American Physical Therapy Association.","volume":"51","author":"SZ George","year":"2021","journal-title":"J Orthop Sports Phys Ther"},{"issue":"4","key":"pone.0297234.ref094","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/ejp.756","article-title":"Group\u2010based task\u2010oriented exercises aimed at managing kinesiophobia improved disability in chronic low back pain","volume":"20","author":"M Monticone","year":"2016","journal-title":"Eur J Pain"},{"issue":"14","key":"pone.0297234.ref095","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1080\/09638288.2020.1863480","article-title":"RETRACTED ARTICLE: Multimodal exercises integrated with cognitive-behavioural therapy improve disability of patients with failed back surgery syndrome: a randomized controlled trial with one-year follow-up","volume":"44","author":"M Monticone","year":"2022","journal-title":"Disabil Rehabil"},{"issue":"6","key":"pone.0297234.ref096","first-page":"959","article-title":"Multidisciplinary program based on early management of psychological factors reduces disability of patients with subacute low back pain: One-year results of a randomized controlled study [retracted in: Eur J Phys Rehabil Med. 2022 Oct 24;:].","volume":"57","author":"M Monticone","year":"2021","journal-title":"Eur J Phys Rehabil Med."},{"key":"pone.0297234.ref097","doi-asserted-by":"crossref","unstructured":"Statement of Retraction [retraction of: Disabil Rehabil. 2022 Jul;44(14):3422\u20133429]. 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