{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:51:29Z","timestamp":1791417089488,"version":"4.3.3"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Young and Middle-Aged Key Personnel Training Project of the Fujian Provincial Health Commission","award":["2019-ZQN-62"],"award-info":[{"award-number":["2019-ZQN-62"]}]},{"DOI":"10.13039\/100017954","name":"Fujian Provincial Finance Department","doi-asserted-by":"publisher","award":["BPB-TSX2021"],"award-info":[{"award-number":["BPB-TSX2021"]}],"id":[{"id":"10.13039\/100017954","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>This study aimed to compare the outcomes of double\u2212armed two\u2212suture longitudinal intussusception microsurgical vasoepididymostomy (LIVE) and single\u2212armed two\u2212suture LIVE techniques in patients with epididymal obstructive azoospermia (EOA). The main outcomes assessed were patency rates, patency time, semen quality and natural pregnancy rates.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Data from patients with EOA who underwent two\u2212suture LIVE were obtained from databases including PubMed, EMBASE, and Web of Science. Weighted data were analyzed using a random\u2212effects model, and weighted mean differences were reported.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 1574 patients with EOA from 24 studies were included. The overall patency rate was approximately 68% (95% confidence interval [CI]: 63\u201372%), with a patency time of approximately 4.63 months (95% CI: 4.15\u20135.12). The sperm concentration reached 26.90 million\/ml and the sperm motility was 23.74%. The natural pregnancy rate was 38% (95% CI: 31\u201346%). The different definitions of patency do not seem to have any meaningful impact when comparing patency rates. There was no significant difference in patency rates, patency time, semen quality and natural pregnancy rates between the double\u2212armed and single\u2212armed LIVE techniques.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The single\u2212armed LIVE is a potential alternative surgical option when high quality double\u2212needle sutures are not easily accessible.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0298019","type":"journal-article","created":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T18:31:29Z","timestamp":1707157889000},"page":"e0298019","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparative evaluation of double- and single-armed two-suture longitudinal intussusception techniques in microsurgical vasoepididymostomy: An updated systematic review and meta-analysis"],"prefix":"10.1371","volume":"19","author":[{"given":"Hong","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiliang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-0836","authenticated-orcid":true,"given":"Songxi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,2,5]]},"reference":[{"issue":"3","key":"pone.0298019.ref001","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.fertnstert.2019.01.004","article-title":"Microsurgical 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