{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T01:55:07Z","timestamp":1785808507311,"version":"3.56.0"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2019YFC1712502"],"award-info":[{"award-number":["2019YFC1712502"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The tribological behaviour of articular cartilage plays a key role in joint motion; however, there is a gap in research on the effect of hyperuricemic joint fluid on cartilage friction behaviour in acute gouty arthritis. In this study, we carried out a fixed-load scratch experiment to compare the friction and wear of articular cartilage under the lubrication of gouty arthritis arthritic fluid and normal human arthritic fluid, and the results showed that the cartilage friction coefficient of patients with acute gouty arthritis was significantly larger than that of normal human beings, and that the cartilage friction coefficient decreased with the elevation of normal load and sliding speed, and the change with the sliding speed varied more differently from that of normal human beings, and that the cartilage surface wear was more severe after prolonged friction. The wear and tear of the cartilage surface is more severe after prolonged friction. Patients with gouty arthritis should reduce the sudden speed changes such as fast running and variable speed running to maintain the stability of the cartilage surface friction coefficient.<\/jats:p>","DOI":"10.1371\/journal.pone.0298722","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T17:35:55Z","timestamp":1711042555000},"page":"e0298722","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Alterations in articular cartilage frictional properties in the setting of acute gouty arthritis"],"prefix":"10.1371","volume":"19","author":[{"given":"Pai","family":"Zheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueer","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcheng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangwei","family":"Che","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2686-8365","authenticated-orcid":true,"given":"Yong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"pone.0298722.ref001","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.2147\/JIR.S357159","article-title":"Combination of Uric Acid and Pro-Inflammatory Cytokines in Discriminating Patients with Gout from Healthy Controls","volume":"15","author":"X Zha","year":"2022","journal-title":"J Inflamm Res"},{"key":"pone.0298722.ref002","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/ar3508","article-title":"T cells as key players for bone destruction in gouty arthritis?","volume":"13","author":"U Harre","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"pone.0298722.ref003","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.3892\/mmr.2016.5526","article-title":"Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects","volume":"14","author":"J Han","year":"2016","journal-title":"Mol Med Rep"},{"key":"pone.0298722.ref004","doi-asserted-by":"crossref","first-page":"8698232","DOI":"10.1155\/2021\/8698232","article-title":"Advances in Experimental and Clinical Research of the Gouty Arthritis Treatment with Traditional Chinese Medicine","volume":"2021","author":"H Liang","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"pone.0298722.ref005","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/s41392-021-00553-z","article-title":"From purines to purinergic signalling: molecular functions and human diseases","volume":"6","author":"Z Huang","year":"2021","journal-title":"Signal Transduct Target Ther"},{"key":"pone.0298722.ref006","first-page":"1326","article-title":"Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4\/MyD88\/NF-\u03baB pathway","volume":"59","author":"X Sun","year":"2021","journal-title":"Pharm Biol"},{"key":"pone.0298722.ref007","first-page":"991","article-title":"Gout arthritis: Pathogenesis, diagnostics and treatment","volume":"145","author":"G. 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