{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T19:00:59Z","timestamp":1773687659026,"version":"3.50.1"},"reference-count":90,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T00:00:00Z","timestamp":1710288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Foundation Dam","award":["426701"],"award-info":[{"award-number":["426701"]}]},{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["170089, 213722, and 213760"],"award-info":[{"award-number":["170089, 213722, and 213760"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>This study examined the longitudinal relationship between a range of personality related variables measured throughout adolescence, and social anxiety disorder (SAD) in young adulthood. In addition, we examined to what degree the phenotypic associations between personality and SAD could be attributed to shared genetic and environmental factors, respectively. A total of 3394 twins (56% females), consisting of seven national birth cohorts from Norway, participated in the study. Personality was measured with self-report questionnaires at three times throughout adolescence, and SAD was measured with a diagnostic interview in early adulthood (<jats:italic>M<\/jats:italic> = 19.1 years, <jats:italic>SD<\/jats:italic> = 1.2). Correlation and regression analyses were performed to examine phenotypic associations between personality and SAD. We then created four composite scores of personality, in which the personality variables from four different ages throughout adolescence were weighted relative to their importance for SAD. Finally, a series of Cholesky decomposition models were used to examine the underlying genetic and environmental influences on the phenotypic associations between composite scores of personality and SAD. The results showed that especially higher neuroticism, lower extraversion, higher levels of loneliness, and lower levels of resilience, self-efficacy and sense of coherence, were associated with SAD. The phenotypic correlations between composite scores of personality and SAD increased from 0.42 when personality was measured 6\u20137 years prior to the assessment of SAD, to 0.52 when personality was measured shortly before the assessment of SAD. These phenotypic associations were mainly due to genetic influences, indicating that personality in adolescence predicts SAD in early adulthood due to shared genetic influences rather than having direct \u2018causal\u2019 effects on SAD.<\/jats:p>","DOI":"10.1371\/journal.pone.0299766","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:25:25Z","timestamp":1710350725000},"page":"e0299766","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["The relationship between personality throughout adolescence and social anxiety disorder in young adulthood. A longitudinal twin study"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6600-9476","authenticated-orcid":true,"given":"Eirunn","family":"Skaug","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trine","family":"Waaktaar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svenn","family":"Torgersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,3,13]]},"reference":[{"key":"pone.0299766.ref001","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-5","author":"American Psychiatric 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and substance use disorders: A meta-analysis.","volume":"136","author":"R Kotov","year":"2010","journal-title":"Psychological Bulletin."},{"issue":"8","key":"pone.0299766.ref008","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.cpr.2002.09.001","article-title":"The five-factor model and personality disorder empirical literature: A meta-analytic review.","volume":"23","author":"LM Saulsman","year":"2004","journal-title":"Clinical Psychology Review"},{"issue":"2","key":"pone.0299766.ref009","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1467-6494.1992.tb00970.x","article-title":"An Introduction to the Five\u2010Factor Model and Its Applications","volume":"60","author":"RR McCrae","year":"1992","journal-title":"Journal of Personality"},{"key":"pone.0299766.ref010","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jad.2021.03.061","article-title":"Associations between facets and aspects of Big Five personality and affective disorders: 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girls.","volume":"48","author":"BL Goldstein","year":"2018","journal-title":"Psychological Medicine."},{"issue":"3","key":"pone.0299766.ref016","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s10578-009-0171-8","article-title":"Temperament, personality and developmental psychopathology: A review based on the conceptual dimensions underlying childhood traits","volume":"41","author":"SSW De Pauw","year":"2010","journal-title":"Child Psychiatry and Human Development"},{"key":"pone.0299766.ref017","first-page":"1","volume-title":"Loneliness: A sourcebook of current theory, research and therapy.","author":"LA Peplau","year":"1982"},{"issue":"1","key":"pone.0299766.ref018","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/1088868319850738","article-title":"The stability and change of loneliness across the life span: A meta-analysis of longitudinal studies.","volume":"24","author":"M Mund","year":"2020","journal-title":"Personality and Social Psychology 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Maes","year":"2019","journal-title":"Developmental Psychology."},{"issue":"2","key":"pone.0299766.ref022","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1207\/s15326985ep2802_3","article-title":"Perceived self-efficacy in cognitive development and functioning","volume":"28","author":"A. Bandura","year":"1993","journal-title":"Educational Psychologist"},{"issue":"4","key":"pone.0299766.ref023","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1177\/0033294117699820","article-title":"Negative life events, social support, and self-efficacy in anxious adolescents.","volume":"120","author":"S Raknes","year":"2017","journal-title":"Psychological Reports."},{"issue":"3","key":"pone.0299766.ref024","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.beth.2011.11.003","article-title":"The relationship among self-efficacy, negative self-referent cognitions, and social anxiety in children: A multiple mediator model.","volume":"43","author":"BM Rudy","year":"2012","journal-title":"Behavior Therapy"},{"issue":"2","key":"pone.0299766.ref025","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1037\/0022-3514.70.2.349","article-title":"IQ and ego-resiliency: Conceptual and empirical connections and separateness","volume":"70","author":"J Block","year":"1996","journal-title":"Journal of Personality and Social Psychology"},{"key":"pone.0299766.ref026","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.paid.2014.11.039","article-title":"A meta-analysis of the trait resilience and mental health.","volume":"76","author":"T Hu","year":"2015","journal-title":"Personality and Individual Differences"},{"key":"pone.0299766.ref027","article-title":"stress, and coping","author":"Antonovsky A. Health","year":"1979","journal-title":"San Francisco: Jossey-Bass"},{"issue":"2","key":"pone.0299766.ref028","first-page":"213","article-title":"The development of a sense of coherence and its impact on responses to stress situations","volume":"126","author":"H Antonovsky","year":"1986","journal-title":"Journal of Social Psychology"},{"issue":"6","key":"pone.0299766.ref029","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/jech.2003.018085","article-title":"Validity of Antonovsky\u2019s sense of coherence scale: A systematic review","volume":"59","author":"M Eriksson","year":"2005","journal-title":"Journal of Epidemiology and Community Health"},{"issue":"1","key":"pone.0299766.ref030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1515\/IJAMH.2008.20.1.85","article-title":"Stability of the sense of coherence in adolescence","volume":"20","author":"PK Honkinen","year":"2008","journal-title":"International Journal of Adolescent Medicine and Health"},{"key":"pone.0299766.ref031","first-page":"99","article-title":"The relationship between life events and sense of coherence in adolescence. 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Cauffman","year":"2004","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"pone.0299766.ref047","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jcrimjus.2018.09.007","article-title":"Longitudinal associations between delinquency, depression and anxiety symptoms in adolescence: Testing the moderating effect of sex and family socioeconomic status","volume":"62","author":"NMG Fontaine","year":"2019","journal-title":"Journal of Criminal Justice"},{"issue":"4","key":"pone.0299766.ref048","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1080\/10615806.2016.1271875","article-title":"Examining the relation between adolescent social anxiety, adolescent delinquency (abstention), and emerging adulthood relationship quality.","volume":"30","author":"N Mercer","year":"2017","journal-title":"Anxiety, Stress, and Coping."},{"key":"pone.0299766.ref049","first-page":"485","volume-title":"Handbook of self-regulation: Research, theory, and applications:","author":"CG DeYoung","year":"2011"},{"issue":"4","key":"pone.0299766.ref050","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s10648-005-5728-9","article-title":"Callous-unemotional traits in predicting the severity and stability of conduct problems and delinquency","volume":"33","author":"PJ Frick","year":"2005","journal-title":"Journal of Abnormal Child Psychology"},{"issue":"6","key":"pone.0299766.ref051","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1017\/thg.2019.51","article-title":"The Oslo University Adolescent and Young Adult Twin Project: Recruitment and attrition","volume":"22","author":"S Torgersen","year":"2019","journal-title":"Twin Research and Human Genetics"},{"issue":"6","key":"pone.0299766.ref052","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1017\/thg.2020.88","article-title":"The Oslo University Adolescent and Young Adult Twin Project: Recruitment and attrition\u2014CORRIGENDUM.","volume":"23","author":"S Torgersen","year":"2020","journal-title":"Twin Research and Human Genetics"},{"key":"pone.0299766.ref053","volume-title":"R Core Team. R: A language and environment for statistical computing.","year":"2021"},{"key":"pone.0299766.ref054","first-page":"107","volume-title":"Personality psychology in Europe.","author":"I Mervielde","year":"1999"},{"issue":"2","key":"pone.0299766.ref055","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1027\/\/1015-5759.17.2.87","article-title":"The structure of children\u2019s perceived self-efficacy: A cross-national study","volume":"17","author":"C Pastorelli","year":"2001","journal-title":"European Journal of Psychological Assessment"},{"key":"pone.0299766.ref056","first-page":"165","article-title":"Development and psychometric evaluation of the resilience scale","volume":"1","author":"GM Wagnild","year":"1993","journal-title":"Journal of Nursing Measurement"},{"issue":"3","key":"pone.0299766.ref057","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1037\/0022-3514.39.3.472","article-title":"The revised UCLA Loneliness Scale: Concurrent and discriminant validity evidence","volume":"39","author":"D Russell","year":"1980","journal-title":"Journal of Personality and Social Psychology"},{"key":"pone.0299766.ref058","volume-title":"Unraveling the mystery of health: How people manage stress and stay well","author":"A. Antonovsky","year":"1987"},{"key":"pone.0299766.ref059","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/02673843.1988.9747643","article-title":"A study of factors associated with the stability of hidden Delinquency","volume":"1","author":"M LeBlanc","year":"1988","journal-title":"International Journal of Adolescence and Youth"},{"issue":"9","key":"pone.0299766.ref060","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1001\/archpsyc.1994.03950090064009","article-title":"Predicting early onset of male antisocial behavior from preschool behavior.","volume":"51","author":"RE Tremblay","year":"1994","journal-title":"Archives of General Psychiatry"},{"issue":"5","key":"pone.0299766.ref061","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1469-7610.1997.tb01545.x","article-title":"The strengths and difficulties questionnaire: A research note","volume":"38","author":"R. Goodman","year":"1997","journal-title":"Journal of Child Psychology and Psychiatry"},{"issue":"11","key":"pone.0299766.ref062","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1097\/00004583-200111000-00015","article-title":"Psychometric properties of the strengths and difficulties questionnaire","volume":"40","author":"R. Goodman","year":"2001","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"issue":"2","key":"pone.0299766.ref063","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1037\/1040-3590.14.2.150","article-title":"Development and validation of a brief form of the multidimensional personality questionnaire","volume":"14","author":"CJ Patrick","year":"2002","journal-title":"Psychological Assessment"},{"issue":"20","key":"pone.0299766.ref064","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10.","volume":"59","author":"DV Sheehan","year":"1998","journal-title":"Journal of Clinical Psychiatry."},{"issue":"9","key":"pone.0299766.ref065","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1017\/S003329172000183X","article-title":"Dimensions over categories: A meta-analysis of taxometric research.","volume":"50","author":"N Haslam","year":"2020","journal-title":"Psychological Medicine."},{"issue":"4","key":"pone.0299766.ref066","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jcv2.12108","article-title":"Seven reasons why binary diagnostic categories should be replaced with empirically sounder and less stigmatizing dimensions.","volume":"2","author":"BB Lahey","year":"2022","journal-title":"JCPP Advances"},{"issue":"3","key":"pone.0299766.ref067","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s10519-020-10031-x","article-title":"Best practices for binary and ordinal data analyses","volume":"51","author":"B Verhulst","year":"2021","journal-title":"Behavior Genetics"},{"key":"pone.0299766.ref068","volume-title":"Methodology for genetic studies of twins and families.","author":"MC Neale","year":"2004"},{"issue":"2","key":"pone.0299766.ref069","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s11336-014-9435-8","article-title":"OpenMx 2.0: Extended structural equation and statistical modeling.","volume":"81","author":"MC Neale","year":"2016","journal-title":"Psychometrika."},{"issue":"3","key":"pone.0299766.ref070","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/BF02294359","article-title":"Factor analysis and AIC.","volume":"52","author":"H. Akaike","year":"1987","journal-title":"Psychometrika."},{"issue":"4","key":"pone.0299766.ref071","doi-asserted-by":"crossref","first-page":"e0232187","DOI":"10.1371\/journal.pone.0232187","article-title":"Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder.","volume":"15","author":"ME Costache","year":"2020","journal-title":"PLoS ONE"},{"key":"pone.0299766.ref072","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/B978-0-12-813004-9.00005-0","volume-title":"Pediatric Anxiety Disorders.","author":"S. Torgersen","year":"2019"},{"issue":"10","key":"pone.0299766.ref073","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jaac.2012.08.002","article-title":"Behavioral inhibition and risk for developing social anxiety disorder: A meta-analytic study","volume":"51","author":"JA Clauss","year":"2012","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"issue":"7","key":"pone.0299766.ref074","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1037\/abn0000769","article-title":"A multimethod, multiinformant study of early childhood temperament and depression and anxiety symptoms in adolescence","volume":"131","author":"TM Olino","year":"2022","journal-title":"Journal of Psychopathology and Clinical Science"},{"key":"pone.0299766.ref075","doi-asserted-by":"crossref","first-page":"103844","DOI":"10.1016\/j.jrp.2019.07.002","article-title":"Clarifying the associations between Big Five personality domains and higher-order psychopathology dimensions in youth","volume":"82","author":"AL Watts","year":"2019","journal-title":"Journal of Research in Personality"},{"key":"pone.0299766.ref076","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jpsychires.2018.04.017","article-title":"Penninx BWJH. The predictive specificity of psychological vulnerability markers for the course of affective disorders","volume":"103","author":"SY Struijs","year":"2018","journal-title":"Journal of Psychiatric Research"},{"issue":"2","key":"pone.0299766.ref077","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1037\/bul0000088","article-title":"A systematic review of personality trait change through intervention.","volume":"143","author":"BW Roberts","year":"2017","journal-title":"Psychological Bulletin"},{"key":"pone.0299766.ref078","first-page":"1","article-title":"Common genetic and environmental bases of the mental disorders and personality traits: Special focus on the hierarchical model of psychopathology and NEO\u2010PI\u2010R facets","author":"D Mitrovi\u0107","year":"2023","journal-title":"Journal of Personality"},{"issue":"8","key":"pone.0299766.ref079","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1001\/jamapsychiatry.2014.655","article-title":"The phenotypic and genetic structure of depression and anxiety disorder symptoms in childhood, adolescence, and young adulthood.","volume":"71","author":"MA Waszczuk","year":"2014","journal-title":"JAMA Psychiatry."},{"issue":"10","key":"pone.0299766.ref080","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1176\/appi.ajp.158.10.1568","article-title":"A review and meta-analysis of the genetic epidemiology of anxiety disorders","volume":"158","author":"JM Hettema","year":"2001","journal-title":"The American Journal of Psychiatry"},{"issue":"5","key":"pone.0299766.ref081","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/CHI.0b013e3180335b12","article-title":"A general population twin study of the CBCL\/6-18 DSM -oriented scales","volume":"46","author":"CAM Spatola","year":"2007","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"pone.0299766.ref082","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/B978-0-12-813004-9.00003-7","volume-title":"Pediatric Anxiety Disorders.","author":"R Cheesman","year":"2019"},{"key":"pone.0299766.ref083","volume-title":"Behavioral genetics.","author":"VS Knopik","year":"2016","edition":"7"},{"issue":"5","key":"pone.0299766.ref084","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s10519-013-9602-1","article-title":"Heritability and the equal environments assumption: Evidence from multiple samples of misclassified twins","volume":"43","author":"D Conley","year":"2013","journal-title":"Behavior Genetics"},{"key":"pone.0299766.ref085","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ssresearch.2013.10.004","article-title":"What can we learn from twin studies? 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Felson","year":"2014","journal-title":"Social Science Research"},{"issue":"1","key":"pone.0299766.ref086","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF01067551","article-title":"A test of the equal-environment assumption in twin studies of psychiatric illness","volume":"23","author":"KS Kendler","year":"1993","journal-title":"Behavior Genetics"},{"issue":"2","key":"pone.0299766.ref087","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s10519-012-9578-2","article-title":"Non-random mating and convergence over time for mental health, life satisfaction, and personality: The Nord-Tr\u00f8ndelag Health Study","volume":"43","author":"H Ask","year":"2013","journal-title":"Behavior Genetics"},{"issue":"1","key":"pone.0299766.ref088","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0301-0511(02)00051-0","article-title":"Biometrical genetics.","volume":"61","author":"DM Evans","year":"2002","journal-title":"Biological Psychology"},{"issue":"1","key":"pone.0299766.ref089","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1186\/1471-2458-12-918","article-title":"Attrition and generalizability in longitudinal studies: Findings from a 15-year population-based study and a Monte Carlo simulation study.","volume":"12","author":"K Gustavson","year":"2012","journal-title":"BMC Public Health."},{"issue":"11","key":"pone.0299766.ref090","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1093\/aje\/kwq257","article-title":"The health status of nonparticipants in a population-based health study","volume":"172","author":"AK Knudsen","year":"2010","journal-title":"American Journal of Epidemiology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0299766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:26:35Z","timestamp":1710350795000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0299766"}},"subtitle":[],"editor":[{"given":"Milica","family":"Nikolic","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,3,13]]},"references-count":90,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,3,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0299766","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,13]]}}}