{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:03:35Z","timestamp":1785888215167,"version":"3.56.0"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T00:00:00Z","timestamp":1715040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22H03299"],"award-info":[{"award-number":["22H03299"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K18370"],"award-info":[{"award-number":["23K18370"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23FA1022"],"award-info":[{"award-number":["23FA1022"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJFR205J"],"award-info":[{"award-number":["JPMJFR205J"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Secondary healthcare data use has been increasing in the dental research field. The validity of the number of remaining teeth assessed from Japanese dental claims data has been reported in several studies, but has not been tested in the general population in Japan.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>To evaluate the validity of the number of remaining teeth assessed from Japanese dental claims data and assess its predictability against subsequent health deterioration.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We used the claims data of residents of a municipality that implemented oral health screening programs. Using the number of teeth in the screening records as the reference standard, we assessed the validity of the claims-based number of teeth by calculating the mean differences. In addition, we assessed the association between the claims-based number of teeth and pneumococcal disease (PD) or Alzheimer\u2019s disease (AD) in adults aged \u226565 years using Cox proportional hazards analyses.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>Of the 10,154 participants, the mean number of teeth assessed from the claims data was 20.9, that in the screening records was 20.5, and their mean difference was 0.5. During the 3-year follow-up, PD or AD onset was observed in 10.4% (3,212\/30,838) and 5.3% (1,589\/30,207) of participants, respectively. Compared with participants with \u226520 teeth, those with 1\u20139 teeth had a 1.29 (95% confidence interval [CI]: 1.17\u20131.43) or 1.19 (95% CI: 1.04\u20131.36) times higher risk of developing PD or AD, respectively.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>High validity of the claims-based number of teeth was observed. In addition, the claims-based number of teeth was associated with the risk of PD and AD.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0299849","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T17:22:50Z","timestamp":1715102570000},"page":"e0299849","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Validity of claims-based definition of number of remaining teeth in Japan: Results from the Longevity Improvement and Fair Evidence Study"],"prefix":"10.1371","volume":"19","author":[{"given":"Yudai","family":"Tamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Kusama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Murata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Osaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhisa","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8769-8955","authenticated-orcid":true,"given":"Kenji","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,5,7]]},"reference":[{"key":"pone.0299849.ref001","article-title":"Short-term effects of reduced cost sharing on childhood dental care utilization and dental caries prevention in Japan","author":"S Ono","year":"2022","journal-title":"Community Dent Oral Epidemiol"},{"key":"pone.0299849.ref002","article-title":"Amoxicillin vs third-generation cephalosporin for infection prophylaxis after third molar extraction","author":"M Sato","year":"2022","journal-title":"Oral Dis"},{"key":"pone.0299849.ref003","doi-asserted-by":"crossref","first-page":"49","DOI":"10.2147\/CLEP.S104448","article-title":"Helping everyone do better: a call for validation studies of routinely recorded health data","volume":"8","author":"V Ehrenstein","year":"2016","journal-title":"Clin Epidemiol"},{"key":"pone.0299849.ref004","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph20031883","article-title":"Oral health promotion under the 8020 Campaign in Japan-A systematic review","volume":"20","author":"S Takehara","year":"2023","journal-title":"Int J Environ Res Public Health"},{"key":"pone.0299849.ref005","unstructured":"National Institute of Health and Nutrition (Japan). 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