{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:27:37Z","timestamp":1791199657375,"version":"4.2.0"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Effective diabetes self-management and collaborative responsibility sharing with parents are imperative for pediatric patients with type 1 diabetes mellitus, particularly as they gradually assume more self-care responsibilities. The primary goal of this study was to assess differences in adherence to self-care activities regarding sociodemographics and clinical characteristics in pediatric patients with type 1 diabetes. The secondary goal of this study was to understand the level of parental involvement in diabetes management and to assess the pediatric patients\u2019 behaviors (independent or dependent on disease self-management) that relate to sociodemographic and clinical characteristics.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This was a comparative cross-sectional and correlational study. The study sample included 182 children and adolescents who had been diagnosed with type 1 diabetes at least 3 months prior. Data collection instruments included a sociodemographic and questionnaire about Adherence to self-care activities and parental involvement in diabetes self-management, as well as a documentation sheet for recording clinical data.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A majority of participants (71%) exhibited non-adherence to self-care tasks, despite 78.0% asserting their independence in diabetes self-management. Notably, insufficient parental involvement in administering insulin therapy significantly predicted severe hypoglycemic episodes.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Pediatric patients dealing with type 1 diabetes demonstrate a substantial degree of autonomy in managing their condition, paradoxically coupled with self-reported non-adherence to critical self-care responsibilities. Notably, children (aged 8\u201312) rely more heavily on parental support, especially concerning insulin therapy administration. The study underscores the crucial role of parental engagement in insulin therapy, as its deficiency significantly predicts the likelihood of severe hypoglycemic episodes.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0300055","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T18:27:26Z","timestamp":1709663246000},"page":"e0300055","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Self-care activities in pediatric patients with type 1 diabetes mellitus"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7374-1035","authenticated-orcid":true,"given":"Mirjana","family":"Smudja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Milenkovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Minakovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Zdravkovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovan","family":"Javorac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2693-543X","authenticated-orcid":true,"given":"Dragana","family":"Milutinovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"key":"pone.0300055.ref001","volume-title":"IDF diabetes atlas","author":"International Diabetes Federation","year":"2021","edition":"1"},{"key":"pone.0300055.ref002","first-page":"47","article-title":"Dr. Milan Jovanovic Batut","volume":"28","author":"Institute for Public Health of Serbia","year":"2021","journal-title":"Serbian Diabetes Registry"},{"issue":"1","key":"pone.0300055.ref003","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4094\/chnr.2023.29.1.7","article-title":"Family-centered interventions for children and adolescents with type 1 diabetes mellitus: an integrative review","volume":"29","author":"A Ispriantari","year":"2023","journal-title":"Child Health Nurs Res"},{"issue":"3","key":"pone.0300055.ref004","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/hex.12041","article-title":"Self-care support in paediatric patients with type 1 diabetes: bridging the gap between patient education and health promotion? 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Kickbusch","year":"1989","journal-title":"Soc Sci Med"},{"issue":"5","key":"pone.0300055.ref007","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3810\/pgm.2009.09.2059","article-title":"The 600-step program for type 1 diabetes self-management in youth: the magnitude of the self-management task","volume":"121","author":"RD Coffen","year":"2009","journal-title":"Postgrad Med"},{"issue":"5","key":"pone.0300055.ref008","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.pedn.2015.06.005","article-title":"Moving the journey towards independence: adolescents transitioning to successful diabetes self-management","volume":"30","author":"E Babler","year":"2015","journal-title":"J Pediatr Nurs"},{"issue":"8","key":"pone.0300055.ref009","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s11892-015-0621-6","article-title":"A review of adolescent adherence in type 1 diabetes and the untapped potential of diabetes providers to improve 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https:\/\/www.paragraf.rs\/propisi\/zakon_o_pravima_pacijenata.html"},{"issue":"1","key":"pone.0300055.ref025","first-page":"1005","article-title":"Concept of family and its importance in clinical practice.","volume":"1","author":"K Rajamohanan Pillai","year":"2021","journal-title":"Ann Community Med Public Health"},{"key":"pone.0300055.ref026","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2147\/DMSO.S313837","article-title":"Managing severe hypoglycaemia in patients with diabetes: current challenges and emerging therapies","volume":"16","author":"H Demirbilek","year":"2023","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"11","key":"pone.0300055.ref027","first-page":"817","article-title":"Fluid management in children with diabetic ketoacidosis.","volume":"66","author":"S McGregor","year":"2020","journal-title":"Can Fam 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parents with type 1 diabetes","volume":"16","author":"KA Driscoll","year":"2016","journal-title":"Curr Diab Rep"},{"issue":"3","key":"pone.0300055.ref037","doi-asserted-by":"crossref","first-page":"273","DOI":"10.2298\/VSP150203007J","article-title":"Problems in diabetes management in school setting in children and adolescents with type 1 diabetes in Serbia.","volume":"73","author":"MD Je\u0161i\u0107","year":"2016","journal-title":"Vojnosanit Pregl."},{"key":"pone.0300055.ref038","first-page":"13674935231168911","article-title":"Self-care management among children and adolescents with diabetes mellitus in Malaysia.","volume":"8","author":"NS Mohd Nor","year":"2023","journal-title":"J Child Health Care"},{"issue":"2","key":"pone.0300055.ref039","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/0145721719894903","article-title":"An Effective Model of Diabetes Care and Education: Revising the AADE7 Self-Care Behaviors\u00ae.","volume":"46","author":"American Association of 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children\u2019s and adolescents\u2019 quality of life?","volume":"27","author":"R Khemakhem","year":"2020","journal-title":"Arch Pediatr."},{"issue":"1","key":"pone.0300055.ref043","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/pedi.12784","article-title":"Association of insulin-manipulation and psychiatric disorders: a systematic epidemiological evaluation of adolescents with type 1 diabetes in Austria.","volume":"20","author":"G Berger","year":"2019","journal-title":"Pediatr Diabetes"},{"key":"pone.0300055.ref044","doi-asserted-by":"crossref","first-page":"113733","DOI":"10.1016\/j.psychres.2021.113733","article-title":"Non-suicidal self-injury in adolescents and young adults with type 1 diabetes: clinical characteristics from a German diabetes-patient registry (DPV).","volume":"297","author":"A Eckert","year":"2021","journal-title":"Psychiatry Res."},{"key":"pone.0300055.ref045","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cpr.2015.02.009","article-title":"Gender differences in the prevalence of nonsuicidal self-injury: A meta-analysis.","volume":"38","author":"K Bresin","year":"2015","journal-title":"Clin Psychol Rev"},{"key":"pone.0300055.ref046","first-page":"100325","article-title":"The relationship between diabetic ketoacidosis and suicidal or self-injurious behaviour: A systematic review","volume":"34","author":"L Al Alshaikh","year":"2023","journal-title":"J Clin Transl Endocrinol"},{"issue":"3","key":"pone.0300055.ref047","doi-asserted-by":"crossref","first-page":"596","DOI":"10.3390\/nu14030596","article-title":"Adherence to the Mediterranean Diet is associated with better metabolic features in youths with type 1 diabetes","volume":"14","author":"V Antoniotti","year":"2022","journal-title":"Nutrients"},{"issue":"3","key":"pone.0300055.ref048","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s11892-018-0981-9","article-title":"Family-based Interventions targeting improvements in health and family outcomes of children and adolescents with type 1 diabetes: a systematic review","volume":"18","author":"MA Feldman","year":"2018","journal-title":"Curr Diab Rep"},{"key":"pone.0300055.ref049","doi-asserted-by":"crossref","first-page":"110153","DOI":"10.1016\/j.diabres.2022.110153","article-title":"Quality of life and psychological well-being among children and adolescents with diabetes and their caregivers using open-source automated insulin delivery systems: findings from a multinational survey","volume":"196","author":"C Knoll","year":"2023","journal-title":"Diabetes Res Clin 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An intervention to reduce fear of hypoglycemia in caregivers of adolescents with type 1 diabetes: study design and participant characteristics.","volume":"118","author":"HK O\u2019Donnell","year":"2022","journal-title":"Contemp Clin Trials."},{"issue":"9","key":"pone.0300055.ref053","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1177\/0193945913516546","article-title":"Self-management as a mediator of family functioning and depressive symptoms with health outcomes in youth with type 1 diabetes","volume":"36","author":"R Whittemore","year":"2014","journal-title":"West J Nurs Res"},{"issue":"4","key":"pone.0300055.ref054","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1464-5491.2008.02399.x","article-title":"Are family factors universally related to metabolic outcomes in adolescents with type 1 diabetes?","volume":"25","author":"FJ Cameron","year":"2008","journal-title":"Diabet Med"},{"issue":"6","key":"pone.0300055.ref055","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/pedi.13053","article-title":"Nutrition habits of children and adolescents with type 1 diabetes changed in a 10\u2009years span.","volume":"21","author":"C Maffeis","year":"2020","journal-title":"Pediatr Diabetes."},{"issue":"1","key":"pone.0300055.ref056","doi-asserted-by":"crossref","first-page":"e000663","DOI":"10.1136\/bmjdrc-2019-000663","article-title":"Dietary intake and eating patterns of young children with type 1 diabetes achieving glycemic targets","volume":"7","author":"R Seckold","year":"2019","journal-title":"BMJ Open Diabetes Res Care"},{"issue":"7","key":"pone.0300055.ref057","doi-asserted-by":"crossref","first-page":"102564","DOI":"10.1016\/j.dsx.2022.102564","article-title":"Impact of decreased physical activity due to COVID restrictions on cardio-metabolic risk parameters in Indian children and youth with type 1 diabetes","volume":"16","author":"N Shah","year":"2022","journal-title":"Diabetes Metab Syndr"},{"issue":"9","key":"pone.0300055.ref058","doi-asserted-by":"crossref","first-page":"4475","DOI":"10.3390\/ijerph18094475","article-title":"Physical activity in adolescents with and without type 1 diabetes during the New Zealand COVID-19 pandemic lockdown of 2020","volume":"18","author":"DM Telford","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"pone.0300055.ref059","doi-asserted-by":"crossref","first-page":"110697","DOI":"10.1016\/j.diabres.2023.110697","article-title":"Youth with type 1 diabetes mellitus are more inactive and sedentary than apparently healthy peers: a systematic review and meta-analysis","volume":"200","author":"N Huerta-Uribe","year":"2023","journal-title":"Diabetes Res Clin Pract"},{"issue":"23","key":"pone.0300055.ref060","first-page":"00110","article-title":"Assessment of a new home-based care pathway for children newly diagnosed with type 1 diabetes","volume":"S1751-9918","author":"L Gauche","year":"2023","journal-title":"Prim Care Diabetes"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T18:28:16Z","timestamp":1709663296000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300055"}},"subtitle":[],"editor":[{"given":"Myriam M.","family":"Altamirano-Bustamante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,3,5]]},"references-count":60,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,3,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0300055","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,5]]}}}