{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T23:50:15Z","timestamp":1774396215973,"version":"3.50.1"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Faced with the increase in the number of chronic diseases with the aging of the population, and with the observation of the insufficiency of therapeutic control, a new need has emerged, that of having a patient as a partner in care.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This study is a randomized controlled trial. Patients with coronary heart disease will be recruited from one clinical site and randomly assigned into two groups: the intervention group and the control group. All participants will be followed up for a total of one year (with three-time points for data collection). Patients who are assigned to the intervention group will receive therapeutic education at first. The digital platform will then allow healthcare providers to accompany them outside the hospital walls. The primary outcome is the incidence of major cardiovascular events within one year of discharge. Main secondary outcomes include changes in health behaviors, medication adherence, and quality of life score. The digital platform is a multi-professional telemonitoring platform that allows care teams to accompany the patient outside the hospital walls. It allows the collection and transmits information from the patient\u2019s home to the therapeutic education team. All data will be secured at a certified host. The patient application provides data on compliance, adherence to physical activity (number of steps taken per day), adequate diet (weight gain, food consumed during the meal, compliance with low-salt or salt-free diet, diabetic diet), smoking cessation, as well as medication adherence. Access to educational tools (digital media) is provided to all initial program participants. These tools will be updated annually by the rehabilitation team on the recommendations. The platform also offers the possibility of organizing an individual or group remote educational session (videoconference modules allowing group and individual sessions), a secure integrated caregiver-patient messaging system. The control group will receive the usual controls at the hospital.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Discussion<\/jats:title>\n<jats:p>To offer a complete solution of care to our patients, we have thought of setting up a digital platform that aims to monitor the patient and strengthen their abilities to manage their condition daily. This pilot experience could be generalized to several services and disciplines. It could be used in several research works.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Trial registration<\/jats:title>\n<jats:p>Trial registered with the Pan African Clinical Trial Registry (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/pactr.samrc.ac.za\" xlink:type=\"simple\">PACTR202307694422939<\/jats:ext-link>). URL: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/pactr.samrc.ac.za\/TrialDisplay.aspx?TrialID=24247\" xlink:type=\"simple\">https:\/\/pactr.samrc.ac.za\/TrialDisplay.aspx?TrialID=24247<\/jats:ext-link>.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0300250","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T18:02:19Z","timestamp":1713463339000},"page":"e0300250","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Therapeutic education of patients with coronary heart disease: Impact of digital platform monitoring in preventing major cardiovascular events in Tunisia: Study protocol"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5330-9069","authenticated-orcid":true,"given":"Hela","family":"Ghali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aymen","family":"El Hraiech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hend","family":"Ben Souda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majdi","family":"Karray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Pavy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chekib","family":"Zedini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"pone.0300250.ref001","unstructured":"World Health Organization. Cardiovascular diseases (CVDs) [Internet]. Geneva; 2017 [cit\u00e9 10 mai 2019]. Disponible sur: http:\/\/www.who.int\/mediacentre\/factsheets\/fs317\/en\/"},{"key":"pone.0300250.ref002","author":"OMS","year":"2014","journal-title":"Les maladies cardiaques, premi\u00e8re cause de mortalit\u00e9 en Tunisie"},{"issue":"3","key":"pone.0300250.ref003","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.pec.2010.03.015","article-title":"Efficacy of therapeutic patient education in chronic diseases and obesity.","volume":"79","author":"G Lagger","year":"2010","journal-title":"Patient Educ Couns. juin"},{"issue":"6","key":"pone.0300250.ref004","doi-asserted-by":"crossref","first-page":"e000025","DOI":"10.1161\/HCQ.0000000000000025","article-title":"Evidence for Therapeutic Patient Education Interventions to Promote Cardiovascular Patient Self-Management: A Scientific Statement for Healthcare Professionals From the American Heart Association.","volume":"10","author":"S Barnason","year":"2017","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"pone.0300250.ref005","article-title":"Patient education in the management of coronary heart disease.","author":"L Anderson","journal-title":"Cochrane Heart Group, \u00e9diteur. Cochrane Database Syst Rev"},{"key":"pone.0300250.ref006","volume-title":"Report of a WHO working group.","author":"WHO","year":"2021"},{"issue":"9","key":"pone.0300250.ref007","doi-asserted-by":"crossref","first-page":"e011793","DOI":"10.1161\/JAHA.118.011793","article-title":"Association Between Medication Adherence and 1\u2010Year Major Cardiovascular Adverse Events After Acute Myocardial Infarction in China.","volume":"8","author":"P Shang","year":"2019","journal-title":"J Am Heart Assoc"},{"issue":"23","key":"pone.0300250.ref008","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1056\/NEJMsa053935","article-title":"Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980\u20132000","volume":"356","author":"ES Ford","year":"2007","journal-title":"N Engl J Med"},{"issue":"5","key":"pone.0300250.ref009","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/s11427-018-9281-6","article-title":"Ideal cardiovascular health and incidence of atherosclerotic 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Cardiovascular Health Promotion and Disease Reduction: The American Heart Association\u2019s Strategic Impact Goal Through 2020 and Beyond.","volume":"121","author":"DM Lloyd-Jones","year":"2010","journal-title":"Circulation."},{"issue":"6","key":"pone.0300250.ref018","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s10557-008-6137-4","article-title":"Effect of an Educational Program (PEGASE) on Cardiovascular Risk in Hypercholesterolaemic Patients.","volume":"22","author":"E Bruckert","year":"2008","journal-title":"Cardiovasc Drugs Ther. d\u00e9c"},{"issue":"1","key":"pone.0300250.ref019","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.acvd.2008.09.014","article-title":"Efficacy over time of a short overall atherosclerosis management programme on the reduction of cardiovascular risk in patients after an acute coronary syndrome","volume":"102","author":"M Lafitte","year":"2009","journal-title":"Arch Cardiovasc Dis. janv"},{"issue":"1","key":"pone.0300250.ref020","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1051\/tpe\/2009013","article-title":"\u00c9valuation d\u2019un programme national en France d\u2019\u00e9ducation th\u00e9rapeutique pour des patients du r\u00e9gime agricole atteints de maladies cardio-vasculaires.","volume":"1","author":"C Crozet","year":"2009","journal-title":"Educ Th\u00e9rapeutique Patient\u2014Ther Patient Educ"},{"issue":"4","key":"pone.0300250.ref021","first-page":"100212","article-title":"\u00c9valuation de l\u2019efficacit\u00e9 d\u2019un programme \u00e9ducatif de pr\u00e9vention de l\u2019ost\u00e9oporose chez les femmes tunisiennes pr\u00e9m\u00e9nopaus\u00e9es travaillant dans des occupations s\u00e9dentaires: protocole de recherche.","volume":"6","author":"A Belgacem","year":"2020","journal-title":"Rev Francoph Int Rech Infirm"},{"issue":"5","key":"pone.0300250.ref022","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.rehab.2012.04.003","article-title":"Therapeutic education in cardiovascular diseases: State of the art and perspectives.","volume":"55","author":"M Labrun\u00e9e","year":"2012","journal-title":"Ann Phys Rehabil Med."},{"issue":"12","key":"pone.0300250.ref023","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.acvd.2013.10.002","article-title":"Therapeutic education in coronary heart disease: Position paper from the Working Group of Exercise Rehabilitation and Sport (GERS) and the Therapeutic Education Commission of the French Society of Cardiology.","volume":"106","author":"B Pavy","year":"2013","journal-title":"Arch Cardiovasc Dis."},{"issue":"3","key":"pone.0300250.ref024","doi-asserted-by":"crossref","first-page":"e17046","DOI":"10.2196\/17046","article-title":"Mobile Apps for Health Behavior Change in Physical Activity, Diet, Drug and Alcohol Use, and 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