{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:23:10Z","timestamp":1762957390178,"version":"3.40.5"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"\nBackground<\/jats:title>\nLess than 50% of non-Hispanic Asian adults taking antihypertensive medication have controlled blood pressure.<\/jats:p>\n<\/jats:sec>\n\nMethods<\/jats:title>\nWe compared non-persistence and low adherence to antihypertensive medication between non-Hispanic Asian and other race\/ethnicity groups among US adults \u226566 years who initiated antihypertensive medication between 2011 and 2018 using a 5% random sample of Medicare beneficiaries (non-Hispanic Asian, n = 2,260; non-Hispanic White, n = 56,000; non-Hispanic Black, n = 5,792; Hispanic, n = 4,212; and Other, n = 1,423). Non-persistence was defined as not having antihypertensive medication available to take in the last 90 of 365 days following treatment initiation. Low adherence was defined as having antihypertensive medication available to take on <80% of the 365 days following initiation.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\nIn 2011\u20132012, 2013\u20132014, 2015\u20132016 and 2017\u20132018, the proportion of non-Hispanic Asian Medicare beneficiaries with non-persistence was 29.1%, 25.6%, 25.4% and 26.7% (p-trend = 0.381), respectively, and the proportion with low adherence was 58.1%, 54.2%, 53.4% and 51.6%, respectively (p-trend = 0.020). In 2017\u20132018, compared with non-Hispanic Asian beneficiaries, non-persistence was less common among non-Hispanic White beneficiaries (risk ratio 0.74 [95%CI, 0.64\u20130.85]), non-Hispanic Black beneficiaries (0.80 [95%CI 0.68\u20130.94]) and those reporting Other race\/ethnicity (0.68 [95%CI, 0.54\u20130.85]) but not among Hispanic beneficiaries (1.04 [95%CI, 0.88\u20131.23]). Compared to non-Hispanic Asian beneficiaries, non-Hispanic White beneficiaries and beneficiaries reporting Other race\/ethnicity were less likely to have low adherence to antihypertensive medication (relative risk 0.78 [95%CI 0.72\u20130.84] and 0.84 [95%CI 0.74\u20130.95], respectively); there was no association for non-Hispanic Black or Hispanic beneficiaries.<\/jats:p>\n<\/jats:sec>\n\nConclusions<\/jats:title>\nNon-persistence and low adherence to antihypertensive medication were more common among older non-Hispanic Asian than non-Hispanic White adults.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0300372","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T17:33:46Z","timestamp":1710956026000},"page":"e0300372","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Antihypertensive medication persistence and adherence among non-Hispanic Asian US patients with hypertension and fee-for-service Medicare health insurance"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3449-0672","authenticated-orcid":true,"given":"Eunhee","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chloe","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Mefford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7619-1649","authenticated-orcid":true,"given":"Kristi","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lama","family":"Ghazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6302-8834","authenticated-orcid":true,"given":"Daichi","family":"Shimbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Muntner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"key":"pone.0300372.ref001","unstructured":"Race and Ethnicity in the United States: 2010 Census and 2020 Census.: United States Census Bureau; 2021. 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