{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:20:40Z","timestamp":1747196440425,"version":"3.40.5"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Central nervous system (CNS) tumors, due to their unique locations, pose a serious threat to human health and present challenges to modern medicine. These tumors exhibit notable epidemiological characteristics across various ethnicities, regions, and age groups. This study investigated the trend of disease burden of CNS tumors in China from 1990\u20132019 and predicted the incidence and death rate from 2020\u20132030. Employing data from the 2019 Global Burden of Disease (GBD) database, we utilized key indicators to scrutinize the disease burden associated with CNS tumors in China. The analysis employed the Joinpoint model to track the trend in disease burden, calculating both the annual percentage change (APC) and average annual percentage change (AAPC). Additionally, the Matlab software facilitated the creation of a gray model to forecast the incidence and death rate of CNS tumors in China spanning from 2020 to 2030.\" In 2019, the age-standardized incidence rate, prevalence rate, death rate, and disability-adjusted life years (DALYs) associated with CNS tumors in China were among the high level in the world. The standardized prevalence rate and DALYs of CNS tumors in China residents showed a stable fluctuation trend with age; however, age-standardized death and incidence rate demonstrated a generally upward trend with age. In China, the age-standardized prevalence and incidence rate of males were lower than those for female residents, while the age-standardized death rate and DALYs among males surpassed those of females. From 1990\u20132019, the age-standardized prevalence and incidence rate of CNS tumors in China exhibited an increasing trend. The age-standardized death rate and DALYs showed a contrasting trend. According to the gray model\u2019s prediction, incidence rate of CNS tumors would continue rising while the death rate is expected to decline in China from 2020\u20132023. The burden of CNS tumors in China has shown an upward trajectory, posing significant challenges to their treatment. It is necessary to pay attention to tertiary prevention, start from the perspective of high-risk groups and high-risk factors to reduce the burden of disease, and achieve \"early detection, early diagnosis, and early treatment\".<\/jats:p>","DOI":"10.1371\/journal.pone.0300390","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T17:40:45Z","timestamp":1713375645000},"page":"e0300390","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis and prediction of central nervous system tumor burden in China during 1990\u20132030"],"prefix":"10.1371","volume":"19","author":[{"given":"Zedi","family":"Qi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangchong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yichen","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mignda","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guozhang","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3581-0536","authenticated-orcid":true,"given":"Shengli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"issue":"1","key":"pone.0300390.ref001","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21708","article-title":"Cancer statistics, 2022.","volume":"72","author":"RL Siegel","year":"2022","journal-title":"CA Cancer J Clin."},{"issue":"4","key":"pone.0300390.ref002","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S1474-4422(18)30468-X","article-title":"Global, regional, and national burden of brain and other CNS cancer, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016.","volume":"18","author":"GBD 2016 Brain and Other CNS Cancer Collaborators","year":"2019","journal-title":"Lancet Neurol."},{"issue":"3","key":"pone.0300390.ref003","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.","volume":"71","author":"H Sung","year":"2021","journal-title":"CA Cancer J Clin."},{"issue":"1","key":"pone.0300390.ref004","first-page":"19","article-title":"Report of cancer epidemiology in China, 2015.","volume":"41","author":"RS Zheng","year":"2019","journal-title":"Zhonghua Zhong Liu Za Zhi."},{"issue":"4","key":"pone.0300390.ref005","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s10552-016-0721-x","article-title":"Air pollution from traffic and risk for brain tumors: a nationwide study in Denmark.","volume":"27","author":"AH Poulsen","year":"2016","journal-title":"Cancer Causes Control"},{"issue":"6","key":"pone.0300390.ref006","first-page":"703","article-title":"Understanding DALYs (disability-adjusted life years).","volume":"16","author":"CJ Murray","year":"1997","journal-title":"J Health Econ.Dec"},{"issue":"9","key":"pone.0300390.ref007","doi-asserted-by":"crossref","first-page":"e0290286","DOI":"10.1371\/journal.pone.0290286","article-title":"The burden of ischemic heart disease and the epidemiologic transition in the Eastern Mediterranean Region: 1990\u20132019.","volume":"18","author":"M Sadeghi","year":"2023","journal-title":"PLoS One."},{"key":"pone.0300390.ref008","doi-asserted-by":"crossref","first-page":"1202980","DOI":"10.3389\/fpubh.2023.1202980","article-title":"Global, regional, and national burden of digestive diseases: findings from the global burden of disease study 2019.","volume":"11","author":"F Wang","year":"2023","journal-title":"Front Public Health"},{"issue":"1","key":"pone.0300390.ref009","doi-asserted-by":"crossref","first-page":"e0280990","DOI":"10.1371\/journal.pone.0280990","article-title":"Direct impact of COVID-19 by estimating disability-adjusted life years at national level in France in 2020.","volume":"18","author":"R Haneef","year":"2023","journal-title":"PLoS One"},{"issue":"31","key":"pone.0300390.ref010","doi-asserted-by":"crossref","first-page":"46859","DOI":"10.1007\/s11356-022-19178-y","article-title":"Yard waste prediction from estimated municipal solid waste using the grey theory to achieve a zero-waste strategy.","volume":"29","author":"MR Islam","year":"2022","journal-title":"Environ Sci Pollut Res Int."},{"key":"pone.0300390.ref011","doi-asserted-by":"crossref","first-page":"105256","DOI":"10.1016\/j.compbiomed.2022.105256","article-title":"Research on physical health early warning based on GM(1,1).","volume":"143","author":"B Zeng","year":"2022","journal-title":"Comput Biol Med"},{"issue":"8","key":"pone.0300390.ref012","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/neuonc\/now127","article-title":"Updates in the management of brain metastases","volume":"18","author":"ND Arvold","year":"2016","journal-title":"Neuro Oncol"},{"issue":"Suppl 4","key":"pone.0300390.ref013","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1093\/neuonc\/nov189","article-title":"CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008\u20132012.","volume":"17","author":"QT Ostrom","year":"2015","journal-title":"Neuro Oncol."},{"issue":"1","key":"pone.0300390.ref014","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/cncr.29015","article-title":"Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010.","volume":"121","author":"HR Gittleman","year":"2015","journal-title":"Cancer"},{"issue":"16","key":"pone.0300390.ref015","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1056\/NEJM198810203191601","article-title":"Tumors of the brain and nervous system after radiotherapy in childhood","volume":"319","author":"E Ron","year":"1988","journal-title":"N Engl J Med"},{"issue":"3","key":"pone.0300390.ref016","doi-asserted-by":"crossref","first-page":"357","DOI":"10.2307\/3579984","article-title":"Intracranial tumors after exposure to ionizing radiation during infancy: a pooled analysis of two Swedish cohorts of 28,008 infants with skin hemangioma","volume":"150","author":"P Karlsson","year":"1998","journal-title":"Radiat Res"},{"issue":"3","key":"pone.0300390.ref017","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.annepidem.2008.12.011","article-title":"An international case-control study of maternal diet during pregnancy and childhood brain tumor risk: a histology-specific analysis by food group.","volume":"19","author":"JM Pogoda","year":"2009","journal-title":"Ann Epidemiol"},{"issue":"1","key":"pone.0300390.ref018","first-page":"71","article-title":"Cancer among farmers: a meta-analysis.","volume":"9","author":"S. Milham","year":"1999","journal-title":"Ann Epidemiol"},{"issue":"3","key":"pone.0300390.ref019","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1002\/(SICI)1097-0274(199809)34:3<252::AID-AJIM7>3.0.CO;2-X","article-title":"Meta-analyses of brain cancer and farming","volume":"34","author":"SA Khuder","year":"1998","journal-title":"Am J Ind Med"},{"key":"pone.0300390.ref020","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.neuro.2016.06.003","article-title":"Long-term exposure to ambient air pollution and incidence of brain tumours: The Danish Nurse Cohort","volume":"55","author":"JT J\u00f8rgensen","year":"2016","journal-title":"Neurotoxicology"},{"issue":"9","key":"pone.0300390.ref021","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s10552-009-9412-1","article-title":"Ambient air pollution and brain cancer mortality","volume":"20","author":"R McKean-Cowdin","year":"2009","journal-title":"Cancer Causes Control"},{"key":"pone.0300390.ref022","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1476-069X-13-55","article-title":"Brain tumours and cigarette smoking: analysis of the INTERPHONE Canada case-control study.","volume":"13","author":"S Vida","year":"2014","journal-title":"Environ Health"},{"issue":"2","key":"pone.0300390.ref023","doi-asserted-by":"crossref","first-page":"e2447","DOI":"10.1097\/MD.0000000000002447","article-title":"Smoking and Glioma Risk: Evidence From a Meta-Analysis of 25 Observational Studies.","volume":"95","author":"C Shao","year":"2016","journal-title":"Medicine (Baltimore)."},{"issue":"10","key":"pone.0300390.ref024","first-page":"3949","article-title":"Ethnicity delineates different genetic pathways in malignant glioma","volume":"61","author":"P Chen","year":"2001","journal-title":"Cancer Res"},{"issue":"3","key":"pone.0300390.ref025","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s11060-020-03530-8","article-title":"Guidelines in the management of CNS tumors","volume":"151","author":"N Redjal","year":"2021","journal-title":"J Neurooncol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T17:41:05Z","timestamp":1713375665000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300390"}},"subtitle":[],"editor":[{"given":"Deepak","family":"Dhamnetiya","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,4,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0300390","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2024,4,17]]}}}