{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T21:46:41Z","timestamp":1793915201601,"version":"4.8.0"},"reference-count":117,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Infant faces readily capture adult attention and elicit enhanced neural processing, likely due to their importance evolutionarily in facilitating bonds with caregivers. Facial malformations have been shown to impact early infant-caregiver interactions negatively. However, it remains unclear how such facial malformations may impact early visual processing. The current study used a combination of eye tracking and electroencephalography (EEG) to investigate adults\u2019 early visual processing of infant faces with cleft lip\/palate as compared to normal infant faces, as well as the impact cleft palate has on perceived cuteness. The results demonstrated a significant decrease in early visual attention to the eye region for infants with cleft palate, while increased visual attention is registered on the mouth region. Increased neural processing of the cleft palate was evident at the N170 and LPP, suggesting differences in configural processing and affective responses to the faces. Infants with cleft palate were also rated significantly less cute than their healthy counterparts (mean difference = .73, p &lt; .001). These results suggest that infants\u2019 faces with cleft lip\/palate are processed differently at early visual perception. These processing differences may contribute to several important aspects of development (e.g., joint attention) and may play a vital role in the previously observed difficulties in mother-infant interactions.<\/jats:p>","DOI":"10.1371\/journal.pone.0300673","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T17:54:26Z","timestamp":1711562066000},"page":"e0300673","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of cleft lip on visual scanning and neural processing of infant faces"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4555-7924","authenticated-orcid":true,"given":"Amanda C.","family":"Hahn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6435-5252","authenticated-orcid":true,"given":"Juergen A.","family":"Riedelsheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zo\u00eb","family":"Royer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Frederick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8779-9197","authenticated-orcid":true,"given":"Rachael","family":"Kee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhiannon","family":"Crimmins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly J.","family":"Jantzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,3,27]]},"reference":[{"issue":"3","key":"pone.0300673.ref001","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1037\/1528-3542.7.3.685","article-title":"That baby caught my eye\u2026 attention capture by infant faces","volume":"7","author":"T. Brosch","year":"2007","journal-title":"Emotion"},{"issue":"4","key":"pone.0300673.ref002","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.evolhumbehav.2013.04.001","article-title":"Sex differences in visual attention toward infant faces","volume":"34","author":"R. A. C\u00e1rdenas","year":"2013","journal-title":"Evolution and Human Behavior"},{"issue":"2","key":"pone.0300673.ref003","doi-asserted-by":"crossref","first-page":"e1664","DOI":"10.1371\/journal.pone.0001664","article-title":"A specific and rapid neural signature for parental instinct","volume":"3","author":"M. L. Kringelbach","year":"2008","journal-title":"PloS one"},{"issue":"4","key":"pone.0300673.ref004","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1037\/ebs0000108","article-title":"A review of infants\u2019 and children\u2019s facial cues\u2019 influence on adults\u2019 perceptions and behaviors.","volume":"12","author":"P. Franklin","year":"2018","journal-title":"Evolutionary Behavioral Sciences"},{"key":"pone.0300673.ref005","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.copsyc.2017.02.010","article-title":"Intuitive parenting: understanding the neural mechanisms of parents\u2019 adaptive responses to infants","volume":"15","author":"C. E. Parsons","year":"2017","journal-title":"Current Opinion in Psychology"},{"issue":"1","key":"pone.0300673.ref006","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0163-6383(01)00068-6","article-title":"Physical attractiveness of premature infants affects outcome at discharge from the NICU","volume":"24","author":"L. K. Badr-Zahr","year":"2001","journal-title":"Infant Behavior and Development"},{"key":"pone.0300673.ref007","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1037\/0012-1649.31.3.464","article-title":"Infant attractiveness predicts maternal behaviors and attitudes","volume":"31","author":"J. H. Langlois","year":"1995","journal-title":"Developmental Psychology"},{"issue":"5","key":"pone.0300673.ref008","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/imhj.20064","article-title":"Influence of infant and child facial cues of low body weight on adults\u2019 ratings of adoption preference, cuteness, and health","volume":"26","author":"A. A. Volk","year":"2005","journal-title":"Infant Mental Health Journal"},{"key":"pone.0300673.ref009","volume-title":"Mother nature: Natural selection and the female of the species","author":"S. B. Hrdy","year":"1999"},{"key":"pone.0300673.ref010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jecp.2009.10.004","article-title":"Increases in parental investment and child health as a result of an early intervention","volume":"106","author":"D. B. Bugental","year":"2010","journal-title":"Journal of Experimental Child Psychology"},{"key":"pone.0300673.ref011","first-page":"51","article-title":"Parenting a child with chronic illness: A metasynthesis","volume":"32","author":"J. S. Coffey","year":"2006","journal-title":"Pediatric Nursing"},{"key":"pone.0300673.ref012","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4103\/2348-2125.150749","article-title":"Psychosocial issues of parents of children with cleft lip and palate in relation to their behavioral problems","volume":"2","author":"P. Thamilselvan","year":"2015","journal-title":"Cleft Lip Palate and Craniofacial Anomalies"},{"issue":"1","key":"pone.0300673.ref013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/jnr.0b013e3182828dbd","article-title":"A qualitative study of psychosocial factors affecting expecting mothers who choose to continue a cleft lip and\/or palate pregnancy to term","volume":"21","author":"Y. T. Hsieh","year":"2013","journal-title":"Journal of Nursing Research"},{"key":"pone.0300673.ref014","volume-title":"Conditional love: parents\u2019 attitudes toward handicapped children","author":"M. Weiss","year":"1994"},{"key":"pone.0300673.ref015","doi-asserted-by":"crossref","first-page":"e6042","DOI":"10.1371\/journal.pone.0006042","article-title":"Gender differences in the motivational processing of babies are determined by their facial attractiveness","volume":"4","author":"R. Yamamoto","year":"2009","journal-title":"PLoS ONE"},{"key":"pone.0300673.ref016","unstructured":"Mossey, P. A., & Catilla, E. E. (2003). Global registry and database on craniofacial anomalies: report of a WHO Registry Meeting on Craniofacial Anomalies\/Main editors: P. Mossey, E. Catilla. In Global registry and database on craniofacial anomalies: report of a WHO Registry Meeting on Craniofacial Anomalies\/Main editors: P. Mossey, E. Catilla."},{"issue":"9703","key":"pone.0300673.ref017","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1016\/S0140-6736(09)60695-4","article-title":"Cleft lip and palate","volume":"374","author":"P. A. Mossey","year":"2009","journal-title":"The Lancet"},{"issue":"2","key":"pone.0300673.ref018","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/jpepsy\/jsr089","article-title":"The role of negative maternal affective states and infant temperament in early interactions between infants with cleft lip and their mothers","volume":"37","author":"R. Montirosso","year":"2012","journal-title":"Journal of Pediatric Psychology"},{"key":"pone.0300673.ref019","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1469-7610.2007.01833.x","article-title":"The effect of cleft lip and palate, and the timing of lip repair on mother-infant interactions and infant development","volume":"49","author":"L. Murray","year":"2008","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"pone.0300673.ref020","doi-asserted-by":"crossref","first-page":"5314657","DOI":"10.1155\/2018\/5314657","article-title":"The effects of maternal mirroring on the development of infant social expressiveness: The case of infant cleft lip","volume":"2018","author":"L. Murray","year":"2018","journal-title":"Neural Plasticity"},{"issue":"3","key":"pone.0300673.ref021","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/jpepsy\/25.3.185","article-title":"Brief report: cognitive and psychomotor development of infants with orofacial clefts","volume":"25","author":"M. L. Speltz","year":"2000","journal-title":"Journal of Pediatric Psychology"},{"issue":"6","key":"pone.0300673.ref022","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/j.1469-7610.2011.02375.x","article-title":"The effect of cleft lip on cognitive development in school\u2010aged children: A paradigm for examining sensitive period effects","volume":"52","author":"F. Hentges","year":"2011","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"pone.0300673.ref023","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1597\/03-028.1","article-title":"Does repairing a cleft lip neonatally have any effect on the longer-term attractiveness of the repair","volume":"41","author":"T. Goodacre","year":"2004","journal-title":"Cleft Palate-Craniofacial Journal"},{"issue":"4","key":"pone.0300673.ref024","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1080\/17470919.2017.1340336","article-title":"Changes in face-specific neural processing explain reduced cuteness and approachability of infants with cleft lip","volume":"13","author":"R. Huffmeijer","year":"2018","journal-title":"Social Neuroscience"},{"key":"pone.0300673.ref025","doi-asserted-by":"crossref","first-page":"112937","DOI":"10.1016\/j.physbeh.2020.112937","article-title":"Attractiveness and neural processing of infant faces: Effects of a facial abnormality but not dopamine","volume":"222","author":"R. Huffmeijer","year":"2020","journal-title":"Physiology & Behavior"},{"issue":"7","key":"pone.0300673.ref026","doi-asserted-by":"crossref","first-page":"e0180499","DOI":"10.1371\/journal.pone.0180499","article-title":"The impact of facial abnormalities and their spatial position on perception of cuteness and attractiveness of infant faces","volume":"12","author":"J. Lewis","year":"2017","journal-title":"Plos one"},{"issue":"10","key":"pone.0300673.ref027","doi-asserted-by":"crossref","first-page":"e25897","DOI":"10.1371\/journal.pone.0025897","article-title":"The effect of cleft lip on adults\u2019 responses to faces: Cross-species findings","volume":"6","author":"C. E. Parsons","year":"2011","journal-title":"PloS one"},{"issue":"5","key":"pone.0300673.ref028","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1597\/16-015","article-title":"Effects of infant cleft lip on adult gaze and perceptions of \u201ccuteness\u201d.","volume":"54","author":"H. Rayson","year":"2017","journal-title":"The Cleft Palate-Craniofacial Journal"},{"issue":"2","key":"pone.0300673.ref029","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1439-0310.1943.tb00655.x","article-title":"Die angeborenen formen m\u00f6glicher erfahrung","volume":"5","author":"K. Lorenz","year":"1943","journal-title":"Zeitschrift f\u00fcr Tierpsychologie"},{"issue":"4","key":"pone.0300673.ref030","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1080\/17470919.2013.795189","article-title":"Minor structural abnormalities in the infant face disrupt neural processing: a unique window into early caregiving responses","volume":"8","author":"C. E. Parsons","year":"2013","journal-title":"Social Neuroscience"},{"issue":"5","key":"pone.0300673.ref031","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1177\/0963721418767873","article-title":"The parental care motivational system and why it matters (for everyone).","volume":"27","author":"M. Schaller","year":"2018","journal-title":"Current Directions in Psychological Science"},{"key":"pone.0300673.ref032","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0163-6383(84)80012-0","article-title":"Early interactions between infants with cranio-facial anomalies and their mothers","volume":"7","author":"T.M. Field","year":"1984","journal-title":"Infant Behavior and Development"},{"issue":"2","key":"pone.0300673.ref033","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0163-6383(94)90048-5","article-title":"Feeding interactions of infants with unrepaired cleft lip and\/or palate","volume":"17","author":"M. L. Speltz","year":"1994","journal-title":"Infant Behavior and Development"},{"issue":"1","key":"pone.0300673.ref034","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1749-6632.2009.04468.x","article-title":"Human social attention","volume":"1156","author":"E. Birmingham","year":"2009","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"2","key":"pone.0300673.ref035","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S1364-6613(99)01436-9","article-title":"Do the eyes have it? Cues to the direction of social attention","volume":"4","author":"S. Langton","year":"2000","journal-title":"Trends in Cognitive Sciences"},{"issue":"6","key":"pone.0300673.ref036","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1067\/mpd.2001.113358","article-title":"Maternal postpartum behaviors and mother-infant relationship during the first year of life","volume":"138","author":"H. L. Britton","year":"2001","journal-title":"The Journal of Pediatrics"},{"issue":"1","key":"pone.0300673.ref037","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1469-7610.1983.tb00109.x","article-title":"Biological basis of social interactions: Implications of research for an understanding of behavioural deviance","volume":"24","author":"H. Papou\u0161ek","year":"1983","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"pone.0300673.ref038","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.infbeh.2016.12.003","article-title":"Maternal gaze to the infant face: Effects of infant age and facial configuration during mother-infant engagement in the first nine weeks","volume":"46","author":"L. De Pascalis","year":"2017","journal-title":"Infant Behavior and Development"},{"issue":"9","key":"pone.0300673.ref039","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1177\/1359105317692856","article-title":"Emotional responses to disfigured faces and disgust sensitivity: An eye-tracking study","volume":"24","author":"A. Stone","year":"2019","journal-title":"Journal of Health Psychology"},{"issue":"1","key":"pone.0300673.ref040","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/0972-6748.57865","article-title":"Event-related potential: An overview","volume":"18","author":"S. Sur","year":"2009","journal-title":"Industrial Psychiatry Journal"},{"key":"pone.0300673.ref041","first-page":"2031","article-title":"A brief introduction to the use of event-related potentials in studies of perception and attention. Attention, Perception, &","volume":"72","author":"G. F. Woodman","year":"2010","journal-title":"Psychophysics"},{"issue":"3","key":"pone.0300673.ref042","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.neuroimage.2003.07.010","article-title":"Early lateralization and orientation tuning for face, word, and object processing in the visual cortex","volume":"20","author":"B. Rossion","year":"2003","journal-title":"Neuroimage"},{"key":"pone.0300673.ref043","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.cortex.2015.11.001","article-title":"Repetition effects in human ERPs to faces","volume":"80","author":"S. R. Schweinberger","year":"2016","journal-title":"Cortex"},{"issue":"6","key":"pone.0300673.ref044","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1162\/jocn.1996.8.6.551","article-title":"Electrophysiological studies of face perception in humans","volume":"8","author":"S. Bentin","year":"1996","journal-title":"Journal of Cognitive Neuroscience"},{"key":"pone.0300673.ref045","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0926-6410(00)00038-0","article-title":"Effects of face inversion on the structural encoding and recognition of faces: Evidence from event-related brain potentials","volume":"10","author":"M. Eimer","year":"2000","journal-title":"Cognitive Brain Research"},{"issue":"6","key":"pone.0300673.ref046","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/cdev.12418","article-title":"Effects of an attachment\u2010based intervention on child protective services\u2013referred mothers\u2019 event\u2010related potentials to children\u2019s emotions.","volume":"86","author":"K. Bernard","year":"2015","journal-title":"Child Development"},{"issue":"1","key":"pone.0300673.ref047","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1017\/S0954579410000714","article-title":"Brain and personality bases of insensitivity to infant cues in neglectful mothers: An event-related potential study","volume":"23","author":"M. J. Rodrigo","year":"2011","journal-title":"Development and Psychopathology"},{"issue":"5","key":"pone.0300673.ref048","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1080\/17470919.2016.1193559","article-title":"Parental reflective functioning and the neural correlates of processing infant affective cues","volume":"12","author":"H. J. Rutherford","year":"2017","journal-title":"Social Neuroscience"},{"issue":"2","key":"pone.0300673.ref049","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.neuroimage.2010.06.029","article-title":"Why is the N170 enhanced for inverted faces? An ERP competition experiment","volume":"53","author":"B. Sadeh","year":"2010","journal-title":"Neuroimage"},{"issue":"2","key":"pone.0300673.ref050","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/1469-8986.3720257","article-title":"Affective picture processing: the late positive potential is modulated by motivational relevance","volume":"37","author":"H. T. Schupp","year":"2000","journal-title":"Psychophysiology"},{"issue":"42","key":"pone.0300673.ref051","doi-asserted-by":"crossref","first-page":"14563","DOI":"10.1523\/JNEUROSCI.3109-12.2012","article-title":"Neural substrate of the late positive potential in emotional processing","volume":"32","author":"Y. Liu","year":"2012","journal-title":"Journal of Neuroscience"},{"issue":"3","key":"pone.0300673.ref052","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.clinph.2008.11.028","article-title":"Motivated and controlled attention to emotion: time-course of the late positive potential","volume":"120","author":"G. Hajcak","year":"2009","journal-title":"Clinical Neurophysiology"},{"key":"pone.0300673.ref053","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ijpsycho.2018.02.002","article-title":"Beyond the FRN: Broadening the time-course of EEG and ERP components implicated in reward processing","volume":"132","author":"J. E. Glazer","year":"2018","journal-title":"International Journal of Psychophysiology"},{"issue":"1","key":"pone.0300673.ref054","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF01578358","article-title":"Facial disfigurement: Problems and management of social interaction and implications for mental health","volume":"14","author":"F. Macgregor","year":"1990","journal-title":"Aesthetic Plastic Surgery"},{"issue":"2","key":"pone.0300673.ref055","first-page":"174","article-title":"Changing faces. Journal of Burn Care &","volume":"19","author":"J. Partridge","year":"1998","journal-title":"Rehabilitation"},{"issue":"6","key":"pone.0300673.ref056","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1080\/01973533.2014.958491","article-title":"Emotional responses to disfigured faces: The influences of perceived anonymity, empathy, and disgust sensitivity","volume":"36","author":"A. Stone","year":"2014","journal-title":"Basic and Applied Social Psychology"},{"key":"pone.0300673.ref057","author":"L.M. DeBruine","year":"2018","journal-title":"Webmorph"},{"issue":"2","key":"pone.0300673.ref058","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3758\/s13428-011-0168-7","article-title":"OpenSesame: An open-source, graphical experiment builder for the social sciences","volume":"44","author":"S. Math\u00f4t","year":"2012","journal-title":"Behavior Research Methods"},{"issue":"4","key":"pone.0300673.ref059","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S1388-2457(00)00527-7","article-title":"The five percent electrode system for high-resolution EEG and ERP measurements","volume":"112","author":"R. Oostenveld","year":"2001","journal-title":"Clinical Neurophysiology"},{"issue":"1","key":"pone.0300673.ref060","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","article-title":"EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis","volume":"134","author":"A. Delorme","year":"2004","journal-title":"Journal of Neuroscience Methods"},{"issue":"2","key":"pone.0300673.ref061","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/1469-8986.3720163","article-title":"Removing electroencephalographic artifacts by blind source separation","volume":"37","author":"T. P. Jung","year":"2000","journal-title":"Psychophysiology"},{"key":"pone.0300673.ref062","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.neuroimage.2019.05.026","article-title":"ICLabel: An automated electroencephalographic independent component classifier, dataset, and website","volume":"198","author":"L. Pion-Tonachini","year":"2019","journal-title":"NeuroImage"},{"issue":"7","key":"pone.0300673.ref063","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.tics.2016.05.003","article-title":"On cuteness: Unlocking the parental brain and beyond","volume":"20","author":"M. L. Kringelbach","year":"2016","journal-title":"Trends in Cognitive Sciences"},{"issue":"10","key":"pone.0300673.ref064","doi-asserted-by":"crossref","first-page":"e106705","DOI":"10.1371\/journal.pone.0106705","article-title":"Baby, you light-up my face: culture-general physiological responses to infants and culture-specific cognitive judgements of adults","volume":"9","author":"G. Esposito","year":"2014","journal-title":"PloS one"},{"issue":"4","key":"pone.0300673.ref065","doi-asserted-by":"crossref","first-page":"e0121554","DOI":"10.1371\/journal.pone.0121554","article-title":"Preference for cute infants does not depend on their ethnicity or species: evidence from hypothetical adoption and donation paradigms","volume":"10","author":"J. Golle","year":"2015","journal-title":"PloS one"},{"issue":"3","key":"pone.0300673.ref066","doi-asserted-by":"crossref","first-page":"e58248","DOI":"10.1371\/journal.pone.0058248","article-title":"Sweet puppies and cute babies: Perceptual adaptation to babyfacedness transfers across species","volume":"8","author":"J. Golle","year":"2013","journal-title":"PloS one"},{"issue":"5","key":"pone.0300673.ref067","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1037\/0012-1649.17.5.650","article-title":"Head shape and the perception of cuteness","volume":"17","author":"T. R. Alley","year":"1981","journal-title":"Developmental Psychology"},{"issue":"2","key":"pone.0300673.ref068","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2466\/pms.1983.56.2.615","article-title":"Age-related changes in body proportions, body size, and perceived cuteness","volume":"56","author":"T. R. Alley","year":"1983","journal-title":"Perceptual and Motor Skills"},{"issue":"3","key":"pone.0300673.ref069","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1439-0310.2008.01603.x","article-title":"Baby schema in infant faces induces cuteness perception and motivation for caretaking in adults","volume":"115","author":"M. L. Glocker","year":"2009","journal-title":"Ethology"},{"issue":"1","key":"pone.0300673.ref070","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1080\/17470218.2012.705860","article-title":"Gender differences in the incentive salience of adult and infant faces","volume":"66","author":"A. C. Hahn","year":"2013","journal-title":"The Quarterly Journal of Experimental Psychology"},{"issue":"8","key":"pone.0300673.ref071","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/j.1439-0310.2012.02068.x","article-title":"Manipulation of infant\u2010like traits affects perceived cuteness of infant, adult and cat faces","volume":"118","author":"A. C. Little","year":"2012","journal-title":"Ethology"},{"issue":"2","key":"pone.0300673.ref072","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1467-9280.2009.02272.x","article-title":"The cutest little baby face: A hormonal link to sensitivity to cuteness in infant faces","volume":"20","author":"R. Sprengelmeyer","year":"2009","journal-title":"Psychological Science"},{"key":"pone.0300673.ref073","first-page":"411","article-title":"Infantile head shape as an elicitor of adult protection.","author":"T. R. Alley","year":"1983","journal-title":"Merrill-Palmer Quarterly"},{"issue":"2","key":"pone.0300673.ref074","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0376-6357(78)90042-6","article-title":"Adults\u2019 responses to infants varying in perceived cuteness","volume":"3","author":"K. A. Hildebrandt","year":"1978","journal-title":"Behavioural Processes"},{"issue":"4","key":"pone.0300673.ref075","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s12110-002-1002-9","article-title":"The influence of infant facial cues on adoption preferences","volume":"13","author":"A. Volk","year":"2002","journal-title":"Human Nature"},{"issue":"9","key":"pone.0300673.ref076","doi-asserted-by":"crossref","first-page":"e46362","DOI":"10.1371\/journal.pone.0046362","article-title":"The power of kawaii: Viewing cute images promotes a careful behavior and narrows attentional focus","volume":"7","author":"H. Nittono","year":"2012","journal-title":"PloS one"},{"issue":"2","key":"pone.0300673.ref077","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1037\/a0014904","article-title":"Viewing cute images increases behavioral carefulness","volume":"9","author":"G. D. Sherman","year":"2009","journal-title":"Emotion"},{"issue":"5","key":"pone.0300673.ref078","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1037\/h0037030","article-title":"Children\u2019s physical attractiveness and sex as determinants of adult punitiveness","volume":"10","author":"K. K. Dion","year":"1974","journal-title":"Developmental Psychology"},{"key":"pone.0300673.ref079","doi-asserted-by":"crossref","first-page":"361","DOI":"10.2307\/1129726","article-title":"Linking family hardship to children\u2019s lives","author":"G. H. Elder","year":"1985","journal-title":"Child Development"},{"key":"pone.0300673.ref080","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.biopsycho.2018.11.011","article-title":"The P200 predominantly reflects distance-to-norm in face space whereas the N250 reflects the activation of identity-specific representations of known faces","volume":"140","author":"S. J. Wuttke","year":"2019","journal-title":"Biological Psychology"},{"issue":"4","key":"pone.0300673.ref081","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/j.neuroimage.2003.12.016","article-title":"Effects of repetition learning on upright, inverted and contrast-reversed face processing using ERPs","volume":"21","author":"R. J. Itier","year":"2004","journal-title":"Neuroimage"},{"issue":"1","key":"pone.0300673.ref082","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/00001756-200001170-00014","article-title":"The N170 occipito-temporal component is delayed and enhanced to inverted faces but not to inverted objects: an electrophysiological account of face-specific processes in the human brain","volume":"11","author":"B. Rossion","year":"2000","journal-title":"Neuroreport"},{"issue":"3","key":"pone.0300673.ref083","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.cogbrainres.2005.03.008","article-title":"The Thatcher illusion seen by the brain: an event-related brain potentials study","volume":"24","author":"C. C. Carbon","year":"2005","journal-title":"Cognitive Brain Research"},{"issue":"6","key":"pone.0300673.ref084","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1111\/1469-8986.00115","article-title":"Turn that frown upside down: ERP effects of thatcherization of misorientated faces","volume":"40","author":"B. Milivojevic","year":"2003","journal-title":"Psychophysiology"},{"key":"pone.0300673.ref085","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neuroimage.2014.04.042","article-title":"Early sensitivity for eyes within faces: A new neuronal account of holistic and featural processing","volume":"97","author":"D. Nemrodov","year":"2014","journal-title":"NeuroImage"},{"issue":"3","key":"pone.0300673.ref086","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0301-0511(99)00013-7","article-title":"Spatio-temporal localization of the face inversion effect: an event-related potentials study","volume":"50","author":"B. Rossion","year":"1999","journal-title":"Biological Psychology"},{"issue":"3","key":"pone.0300673.ref087","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S0306-4522(02)00752-2","article-title":"The spatiotemporal dynamics of the face inversion effect: a magneto-and electro-encephalographic study","volume":"116","author":"S. Watanabe","year":"2003","journal-title":"Neuroscience"},{"issue":"1","key":"pone.0300673.ref088","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1177\/1534582302001001004","article-title":"How does the brain process upright and inverted faces?.","volume":"1","author":"B. Rossion","year":"2002","journal-title":"Behavioral and Cognitive Neuroscience Reviews"},{"key":"pone.0300673.ref089","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.neuropsychologia.2015.09.026","article-title":"Neural and cognitive face-selective markers: An integrative review","volume":"83","year":"2016","journal-title":"Neuropsychologia"},{"issue":"11\u201312","key":"pone.0300673.ref090","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1177\/03010066231198417","article-title":"Face inversion effect on perceived cuteness of infant faces","volume":"52","author":"K. Kuraguchi","year":"2023","journal-title":"Perception"},{"issue":"2","key":"pone.0300673.ref091","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1177\/1948550615609734","article-title":"The face of humanity: Configural face processing influences ascriptions of humanness","volume":"7","author":"K. Hugenberg","year":"2016","journal-title":"Social Psychological and Personality Science"},{"key":"pone.0300673.ref092","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0301-0511(99)00044-7","article-title":"Brain potentials in affective picture processing: Covariation with autonomic arousal and affective report","volume":"52","author":"B. N. Cuthbert","year":"2000","journal-title":"Biological Psychology"},{"key":"pone.0300673.ref093","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1469-8986.2004.00174.x","article-title":"The selective processing of briefly presented affective pictures: An ERP analysis","volume":"41","author":"H. T. Schupp","year":"2004","journal-title":"Psychophysiology"},{"key":"pone.0300673.ref094","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.1992.tb22837.x","article-title":"A review of event-related potential components discovered in the context of studying P3","volume":"658","author":"W. Ritter","year":"1992","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"7","key":"pone.0300673.ref095","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/scan\/nsaa098","article-title":"Attentional conditions differentially affect early, intermediate and late neural responses to fearful and neutral faces","volume":"15","author":"S. Schindler","year":"2020","journal-title":"Social Cognitive and Affective Neuroscience"},{"key":"pone.0300673.ref096","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3389\/fnhum.2012.00033","article-title":"Functional significance of the emotion-related late positive potential","volume":"6","author":"S. B. Brown","year":"2012","journal-title":"Frontiers in Human Neuroscience"},{"issue":"11","key":"pone.0300673.ref097","doi-asserted-by":"crossref","first-page":"e13437","DOI":"10.1111\/psyp.13437","article-title":"Methodological reporting behavior, sample sizes, and statistical power in studies of event\u2010related potentials: Barriers to reproducibility and replicability","volume":"56","author":"P. E. Clayson","year":"2019","journal-title":"Psychophysiology"},{"key":"pone.0300673.ref098","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.cortex.2021.03.013","article-title":"# EEGManyLabs: Investigating the replicability of influential EEG experiments","volume":"144","author":"Y. G. Pavlov","year":"2021","journal-title":"Cortex"},{"issue":"2","key":"pone.0300673.ref099","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/SCS.0000000000005068","article-title":"Eye tracking as a proxy for perceptual evaluation of repaired cleft lip","volume":"30","author":"C. N. Warne","year":"2019","journal-title":"Journal of Craniofacial Surgery"},{"key":"pone.0300673.ref100","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.infbeh.2018.08.001","article-title":"Exploring the morphological and emotional correlates of infant cuteness","volume":"53","author":"M. L. Almanza-Sep\u00falveda","year":"2018","journal-title":"Infant Behavior and Development"},{"issue":"10","key":"pone.0300673.ref101","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1093\/scan\/nsy080","article-title":"Oxytocin reduces neural activation in response to infant faces in nulliparous young women","volume":"13","author":"P. A. Bos","year":"2018","journal-title":"Social Cognitive and Affective Neuroscience"},{"key":"pone.0300673.ref102","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.infbeh.2017.08.005","article-title":"Approach-avoidance responses to infant facial expressions in nulliparous women: associations with early experience and mood induction","volume":"49","author":"P. De Carli","year":"2017","journal-title":"Infant Behavior and Development"},{"issue":"3","key":"pone.0300673.ref103","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1080\/03004430.2014.932153","article-title":"Using infrared thermography to assess emotional responses to infants","volume":"185","author":"G. Esposito","year":"2015","journal-title":"Early Child Development and Care"},{"key":"pone.0300673.ref104","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.yhbeh.2014.11.010","article-title":"The reward value of infant facial cuteness tracks within-subject changes in women\u2019s salivary testosterone","volume":"67","author":"A. C. Hahn","year":"2015","journal-title":"Hormones and Behavior"},{"issue":"3","key":"pone.0300673.ref105","doi-asserted-by":"crossref","first-page":"20140978","DOI":"10.1098\/rsbl.2014.0978","article-title":"Reported maternal tendencies predict the reward value of infant facial cuteness, but not cuteness detection","volume":"11","author":"A. C. Hahn","year":"2015","journal-title":"Biology Letters"},{"issue":"1","key":"pone.0300673.ref106","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.evolhumbehav.2009.05.004","article-title":"Female and male responses to cuteness, age and emotion in infant faces","volume":"31","author":"J. S. Lobmaier","year":"2010","journal-title":"Evolution and Human Behavior"},{"issue":"5","key":"pone.0300673.ref107","doi-asserted-by":"crossref","first-page":"e36270","DOI":"10.1371\/journal.pone.0036270","article-title":"Regional brain responses in nulliparous women to emotional infant stimuli","volume":"7","author":"J. L. Montoya","year":"2012","journal-title":"PloS one"},{"issue":"1","key":"pone.0300673.ref108","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0163-6383(82)80015-5","article-title":"Adults\u2019 responses to infants varying in facial expression and perceived attractiveness","volume":"5","author":"T. G. Power","year":"1982","journal-title":"Infant Behavior and Development"},{"issue":"1","key":"pone.0300673.ref109","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12868-022-00761-5","article-title":"Gender differences in brain response to infant emotional faces","volume":"23","author":"K. Zhang","year":"2022","journal-title":"BMC Neuroscience"},{"issue":"1","key":"pone.0300673.ref110","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/desc.12090","article-title":"Here\u2019s looking at you, kid: Attention to infant emotional faces in mothers and non\u2010mothers","volume":"17","author":"C. Thompson\u2010Booth","year":"2014","journal-title":"Developmental Science"},{"issue":"11","key":"pone.0300673.ref111","doi-asserted-by":"crossref","first-page":"e80379","DOI":"10.1371\/journal.pone.0080379","article-title":"Human infant faces provoke implicit positive affective responses in parents and non-parents alike","volume":"8","author":"V. P. Senese","year":"2013","journal-title":"PloS one"},{"issue":"4","key":"pone.0300673.ref112","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1080\/15295192.2016.1184928","article-title":"Motivated attention and reward in parenting","volume":"16","author":"A. E. Ferrey","year":"2016","journal-title":"Parenting"},{"issue":"3","key":"pone.0300673.ref113","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.biopsycho.2011.11.008","article-title":"Parental and romantic attachment shape brain processing of infant cues","volume":"89","author":"O. Weisman","year":"2012","journal-title":"Biological Psychology"},{"issue":"14","key":"pone.0300673.ref114","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1016\/j.neuropsychologia.2006.06.015","article-title":"Gender and parental status affect the visual cortical response to infant facial expression","volume":"44","author":"A. M. Proverbio","year":"2006","journal-title":"Neuropsychologia"},{"issue":"5","key":"pone.0300673.ref115","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1080\/17470919.2012.672457","article-title":"Investigating the impact of parental status and depression symptoms on the early perceptual coding of infant faces: an event-related potential study","volume":"7","author":"L. K. Noll","year":"2012","journal-title":"Social Neuroscience"},{"issue":"3","key":"pone.0300673.ref116","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1037\/a0035959","article-title":"Motherhood and oxytocin receptor genetic variation are associated with selective changes in electrocortical responses to infant facial expressions","volume":"14","author":"M. J. Peltola","year":"2014","journal-title":"Emotion"},{"key":"pone.0300673.ref117","doi-asserted-by":"crossref","first-page":"104604","DOI":"10.1016\/j.neubiorev.2022.104604","article-title":"Processing children\u2019s faces in the parental brain: A meta-analysis of ERP studies. Neuroscience &","volume":"136","author":"E. Vuoriainen","year":"2022","journal-title":"Biobehavioral Reviews"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T17:55:56Z","timestamp":1711562156000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0300673"}},"subtitle":[],"editor":[{"given":"J. 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