{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T19:50:24Z","timestamp":1793303424375,"version":"4.5.0"},"reference-count":22,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Improvement Fund of the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","award":["(R016031039)"],"award-info":[{"award-number":["(R016031039)"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    This study aimed to assess the effect of intraocular pressure (IOP) changes on biometry and intraocular lens (IOL) power calculation in patients diagnosed with primary open-angle glaucoma (POAG) and ocular hypertension (OHT). This prospective non-randomized cohort study enrolled patients with diagnosed POAG and OHT, presenting with IOP levels exceeding 25 mmHg. Thai Clinical Trials Registry number was TCTR20180912007. Optical biometry, encompassing measurements such as corneal thickness (CCT), keratometry, anterior chamber depth (ACD), and axial length, was conducted before and after IOP reduction. The IOL power was also determined using the SRK\/T formula. The main outcomes measured were alterations in biometry and IOL power. Correlations between IOP, biometric parameters, and IOL power were analyzed. In total, 28 eyes were included in the study, with a mean patient age of 65.71\u00b110.2 years. After IOP reduction, all biometric parameters, except CCT and ACD, exhibited a decrease without reaching statistical significance (all p&gt;0.05). Meanwhile, IOL power showed a slight increase of 0.214\u00b10.42 diopters (P = 0.035). The correlation between IOP and biometric parameters was found to be weak. However, there was a moderate correlation between IOP and IOL power (r\n                    <jats:sup>2<\/jats:sup>\n                    = 0.267). Notably, IOL power tended to increase by more than 0.5 diopters when IOP decreased by more than 10 mmHg (p &lt; 0.001). In conclusion, changes in IOP among patients with POAG and OHT do not significantly impact biometry and IOL power calculations. Nonetheless, it may be prudent to consider a slight adjustment in IOL power when IOP is lowered by more than 10 mmHg.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0304169","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T13:32:27Z","timestamp":1718026347000},"page":"e0304169","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of intraocular pressure change on intraocular lens power calculation in primary open-angle glaucoma and ocular hypertension"],"prefix":"10.1371","volume":"19","author":[{"given":"Chareenun","family":"Chirapapaisan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6073-8106","authenticated-orcid":true,"given":"Akarawit","family":"Eiamsamarng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niphon","family":"Chirapapaisan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wara","family":"Raksong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darin","family":"Sakiyalak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunisa","family":"Koodkaew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audcharawadee","family":"Subunnasenee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"issue":"2","key":"pone.0304169.ref001","article-title":"Refractive Outcomes after Cataract Surgery.","volume":"12","author":"R Khoramnia","year":"2022","journal-title":"Diagnostics (Basel)."},{"key":"pone.0304169.ref002","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ajo.2015.12.004","article-title":"Changes in Axial Length and Refractive Error After Noninvasive Normalization of Intraocular Pressure From Elevated Levels","volume":"163","author":"CS Kim","year":"2016","journal-title":"Am J Ophthalmol"},{"issue":"17","key":"pone.0304169.ref003","article-title":"Factors Associated with Refractive Prediction Error after Phacotrabeculectomy.","volume":"12","author":"JH Shin","year":"2023","journal-title":"J Clin Med."},{"issue":"6","key":"pone.0304169.ref004","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1001\/archopht.120.6.701","article-title":"The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma","volume":"120","author":"MA Kass","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"pone.0304169.ref005","article-title":"Is cataract surgery recommended on a patient with high IOP?.","author":"JM Heltzer","year":"2019"},{"issue":"7","key":"pone.0304169.ref006","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1136\/bjophthalmol-2012-302442","article-title":"Longitudinal changes in anterior chamber depth and axial length in Asian subjects after trabeculectomy surgery","volume":"97","author":"R Husain","year":"2013","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"pone.0304169.ref007","doi-asserted-by":"crossref","first-page":"478","DOI":"10.5301\/ejo.5000604","article-title":"Intraocular lens power changes after mitomycin trabeculectomy.","volume":"25","author":"M Pakravan","year":"2015","journal-title":"Eur J Ophthalmol"},{"issue":"3","key":"pone.0304169.ref008","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4103\/2008-322X.188399","article-title":"Ocular Biometric Changes after Trabeculectomy.","volume":"11","author":"A Alvani","year":"2016","journal-title":"J Ophthalmic Vis Res"},{"key":"pone.0304169.ref009","unstructured":"Expert Interview\u2014Glaucoma Risk Factors With Andrew G. 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