{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:34:13Z","timestamp":1790487253326,"version":"4.1.0"},"reference-count":88,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"publisher","award":["00193-00001615\/2023-00"],"award-info":[{"award-number":["00193-00001615\/2023-00"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"publisher","award":["00193-00002357\/2022-90"],"award-info":[{"award-number":["00193-00002357\/2022-90"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"publisher","award":["00193.00001222\/2021-26"],"award-info":[{"award-number":["00193.00001222\/2021-26"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005668","name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Distrito Federal","doi-asserted-by":"publisher","award":["00193-00001261\/2021-23"],"award-info":[{"award-number":["00193-00001261\/2021-23"]}],"id":[{"id":"10.13039\/501100005668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["310269\/2021"],"award-info":[{"award-number":["310269\/2021"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["402816\/2023-4"],"award-info":[{"award-number":["402816\/2023-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Neuromuscular electrical stimulation (NMES) can improve physical function in different populations. NMES-related outcomes may be influenced by muscle length (i.e., joint angle), a modulator of the force generation capacity of muscle fibers. Nevertheless, to date, there is no comprehensive synthesis of the available scientific evidence regarding the optimal joint angle for maximizing the effectiveness of NMES. We performed a systematic review to investigate the effect of muscle length on NMES-induced torque, discomfort, contraction fatigue, and strength training adaptations in healthy and clinical adult populations (PROSPERO: CRD42022332965). We conducted searches across seven electronic databases: PUBMED, Web of Science, EMBASE, PEDro, BIREME, SCIELO, and Cochrane, over the period from June 2022 to October 2023, without restricting the publication year. We included cross-sectional and longitudinal studies that used NMES as an intervention or assessment tool for comparing muscle lengths in adult populations. We excluded studies on vocalization, respiratory, or pelvic floor muscles. Data extraction was performed via a standardized form to gather information on participants, interventions, and outcomes. Risk of bias was assessed using the Revised Cochrane risk-of-bias tool for cross-over trials and the Physiotherapy Evidence Database scale. Out of the 1185 articles retrieved through our search strategy, we included 36 studies in our analysis, that included 448 healthy young participants (age: 19\u201340 years) in order to investigate maximum evoked torque (n = 268), contraction fatigability (n = 87), discomfort (n = 82), and muscle strengthening (n = 22), as well as six participants with spinal cord injuries, and 15 healthy older participants. Meta-analyses were possible for comparing maximal evoked torque according to quadriceps muscle length through knee joint angle. At optimal muscle length 50\u00b0 - 70\u00b0 of knee flexion, where 0\u00b0 is full extension), there was greater evoked torque during nerve stimulation compared to very short (0 \u2013 30\u00b0) (p&lt;0.001, CI 95%: -2.03, -1.15 for muscle belly stimulation, and -3.54, -1.16 for femoral nerve stimulation), short (31\u00b0 - 49\u00b0) (p = 0.007, CI 95%: -1.58, -0.25), and long (71\u00b0 - 90\u00b0) (p&lt;0.001, CI 95%: 0.29, 1.02) muscle lengths. At long muscle lengths, NMES evoked greater torque than very short (p&lt;0.001, CI 95%: -2.50, -0.67) and short (p = 0.04, CI 95%: -2.22, -0.06) lengths. The shortest quadriceps length generated the highest perceived discomfort for a given current amplitude. The amount of contraction fatigability was greater when muscle length allowed greater torque generation in the pre-fatigue condition. Strength gains were greater for a protocol at the optimal muscle length than for short muscle length. The quality of evidence was very high for most comparisons for evoked torque. However, further studies are necessary to achieve certainty for the other outcomes. Optimal muscle length should be considered the primary choice during NMES interventions, as it promotes higher levels of force production and may facilitate the preservation\/gain in muscle force and mass, with reduced discomfort. However, a longer than optimal muscle length may also be used, due to possible muscle lengthening at high evoked tension. Thorough understanding of these physiological principles is imperative for the appropriate prescription of NMES for healthy and clinical populations.<\/jats:p>","DOI":"10.1371\/journal.pone.0304205","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T17:32:17Z","timestamp":1718040737000},"page":"e0304205","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Effect of muscle length on maximum evoked torque, discomfort, contraction fatigue, and strength adaptations during electrical stimulation in adult populations: A systematic review"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4082-1092","authenticated-orcid":true,"given":"Jonathan Galv\u00e3o Ten\u00f3rio","family":"Cavalcante","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Hugo de Souza","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita de C\u00e1ssia","family":"Marqueti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel de Almeida","family":"Paz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falia Aguillar Ivo","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6741-3502","authenticated-orcid":true,"given":"Marco Aur\u00e9lio","family":"Vaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6563-503X","authenticated-orcid":true,"given":"Nicolas","family":"Babault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Luiz 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after anterior cruciate ligament surgery","volume":"68","author":"A Delitto","year":"1988","journal-title":"Phys Ther"},{"issue":"1","key":"pone.0304205.ref033","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1249\/00005768-198502000-00023","article-title":"Influence of sex differences and knee joint position on electrical stimulation-modulated strength increases","volume":"17","author":"TD Fahey","year":"1985","journal-title":"Med Sci Sports Exerc"},{"issue":"7","key":"pone.0304205.ref034","doi-asserted-by":"crossref","first-page":"e1000100","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"6","author":"A Liberati","year":"2009","journal-title":"PLoS Med"},{"key":"pone.0304205.ref035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for 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Fitch","year":"1985","journal-title":"J Physiol"},{"issue":"4","key":"pone.0304205.ref045","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3928\/19425864-20150707-07","article-title":"Knee joint angle influences neuromuscular electrical stimulation-induced torque","volume":"7","author":"CB Bremner","year":"2015","journal-title":"Athletic Training and Sports Health Care"},{"issue":"3","key":"pone.0304205.ref046","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/BF02368005","article-title":"Effects of joint angle, electrodes and waveform on electrical stimulation of the quadriceps and hamstrings","volume":"16","author":"DR McNeal","year":"1988","journal-title":"Ann Biomed Eng"},{"issue":"5","key":"pone.0304205.ref047","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3928\/19425864-20150831-03","article-title":"Assessment of Comfort During NMES-induced Quadriceps Contractions at Two Knee Joint Angles","volume":"7","author":"CB 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