{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T19:45:01Z","timestamp":1769975101470,"version":"3.49.0"},"reference-count":40,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Youth Program of National Social Science Fund of China","award":["21CYY011"],"award-info":[{"award-number":["21CYY011"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>This study aims to investigate the effect of detoxification on acoustic features of Mandarin speech. Speech recordings were collected from 66 male abstinent heroin users with different durations of drug detoxification, specifically early abstinent users with a detoxification duration of less than 2 years, sustained abstinent users with 2 years of detoxification, and long-term abstinent users with a detoxification duration of more than 2 years. The results of the acoustic analyses showed that early abstinent users exhibited lower loudness, relative energies of F1, F2, and F3, higher H1\u2013A3, and fewer loudness peaks per second, as well as a longer average duration of unvoiced segments, compared to the sustained and long-term abstinent users. The findings suggest that detoxification may lead to a rehabilitation process in the speech production of abstinent heroin users (e.g., less vocal hoarseness). This study not only provides valuable insights into the effect of detoxification on speech production but also provides a theoretical basis for the speech rehabilitation and detoxification treatment of heroin users.<\/jats:p>","DOI":"10.1371\/journal.pone.0304399","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T17:29:44Z","timestamp":1718213384000},"page":"e0304399","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of detoxification on acoustic features of Mandarin speech in male heroin users"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5126-9187","authenticated-orcid":true,"given":"Puyang","family":"Geng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ningxue","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Ling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"pone.0304399.ref001","doi-asserted-by":"crossref","first-page":"699074","DOI":"10.3389\/fpsyt.2021.699074","article-title":"Tracking study on the relapse and aftercare effect of drug patients released from a compulsory isolated detoxification center","volume":"12","author":"N Liu","year":"2022","journal-title":"Front Psychiatry"},{"key":"pone.0304399.ref002","first-page":"1","article-title":"National trends and characteristics of inpatient detoxification for drug use disorders in the United States","volume":"18","author":"H Zhu","year":"2018","journal-title":"BMC Public Health"},{"key":"pone.0304399.ref003","volume-title":"Interpersonal communication: Building connections together","author":"TK Gamble","year":"2013"},{"key":"pone.0304399.ref004","first-page":"237","article-title":"Repercuss\u00f5es otorrinolaringol\u00f3gicas do abuso de coca\u00edna e\/ou crack em dependentes de drogas","volume":"45","author":"A Nassif Filho","year":"1999","journal-title":"Rev Assoc M\u00e9dica Bras"},{"key":"pone.0304399.ref005","volume-title":"Voice science","author":"RT Sataloff","year":"2005"},{"key":"pone.0304399.ref006","first-page":"108","article-title":"An acoustic analysis of cannabis-intoxicated speech","volume":"47","author":"A Shamei","year":"2019","journal-title":"Can Acoust"},{"key":"pone.0304399.ref007","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.21437\/Interspeech.2017-621","article-title":"Phonological Markers of Oxytocin and MDMA Ingestion","author":"C Agurto","year":"2017","journal-title":"Interspeech"},{"key":"pone.0304399.ref008","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/s41386-020-0620-4","article-title":"Detection of acute 3, 4-methylenedioxymethamphetamine (MDMA) effects across protocols using automated natural language processing","volume":"45","author":"C Agurto","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"pone.0304399.ref009","doi-asserted-by":"crossref","unstructured":"Agurto C, Norel R, Pietrowicz M, Parvaz M, Kinreich S, Bachi K, et al. 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