{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:21:43Z","timestamp":1785410503851,"version":"3.56.0"},"reference-count":53,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020951","name":"Fonds de Recherche du Qu\u00e9bec","doi-asserted-by":"publisher","award":["324497"],"award-info":[{"award-number":["324497"]}],"id":[{"id":"10.13039\/501100020951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Problematic Internet use is characterized by excessive use of online platforms that can result in social isolation, family problems, psychological distress, and even suicide. Problematic Internet use has been associated with cannabis use disorder, however knowledge on the adult population remains limited. In Quebec, cannabis use has significatively increased since 2018, and it is associated with various risks in public safety, public health, and mental health. This study aims to identify factors associated with problematic Internet use among adult cannabis users and to better understand their experiences.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Method<\/jats:title>\n<jats:p>This project is a mixed explanatory sequential study consisting of two phases. Phase 1 (n = 1500) will be a cross-sectional correlational study using probability sampling to examine variables that predispose individuals to problematic Internet use, characteristics associated with cannabis use, Internet use, and the mental health profile of adult cannabis users in Quebec. Descriptive analyses and regression models will be used to determine the relationship between cannabis use and Internet use. Phase 2 (n = 45) will be a descriptive qualitative study in the form of semi-structured interviews aimed at better understanding the experience and background of cannabis users with probable problematic Internet use.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Discussion<\/jats:title>\n<jats:p>The results of this study will support the development of public policies and interventions for the targeted population, by formulating courses of action that contribute to the prevention and reduction of harms associated with cannabis use and problematic Internet use. Furthermore, an integrated knowledge mobilization plan will aid in the large-scale dissemination of information that can result useful to decision-makers, practitioners, members of the scientific community, and the general population regarding the use of cannabis and the Internet.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0304697","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T17:32:04Z","timestamp":1717435924000},"page":"e0304697","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cannabis use, mental health, and problematic Internet use in Quebec: A study protocol"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3856-1877","authenticated-orcid":true,"given":"Magaly","family":"Brodeur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Jutras-Aswad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9e-Anne","family":"L\u00e9gar\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e8le","family":"Morvannou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Monson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie-Christine","family":"Cotton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5800-8975","authenticated-orcid":true,"given":"Anders","family":"Hakansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Parent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6140-9916","authenticated-orcid":true,"given":"Catherine","family":"Hudon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"key":"pone.0304697.ref001","author":"Enqu\u00eate qu\u00e9b\u00e9coise sur le cannabis 2021","year":"2021","journal-title":"Institut de la Statistique du Qu\u00e9bec"},{"key":"pone.0304697.ref002","author":"Enqu\u00eate qu\u00e9b\u00e9coise sur le cannabis 2019","year":"2019","journal-title":"Institut de la Statistique du Qu\u00e9bec"},{"key":"pone.0304697.ref003","author":"Coup d\u2019\u0153il sur le cannabis","year":"2019","journal-title":"Institut national de sant\u00e9 publique du Qu\u00e9bec"},{"issue":"1","key":"pone.0304697.ref004","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41572-021-00247-4","article-title":"Cannabis use and cannabis use disorder.","volume":"7","author":"JP Connor","year":"2021","journal-title":"Nat Rev Dis Primer."},{"issue":"8","key":"pone.0304697.ref005","doi-asserted-by":"crossref","first-page":"e0255872","DOI":"10.1371\/journal.pone.0255872","article-title":"Association patterns of cannabis abuse and dependence with risk of problematic non-substance-related dysregulated and addictive behaviors.","volume":"16","author":"JC Perales","year":"2021","journal-title":"PLOS ONE."},{"key":"pone.0304697.ref006","first-page":"239","volume-title":"Behavioral addictions: DSM-5\u00ae and beyond","author":"NM Petry","year":"2016"},{"issue":"11","key":"pone.0304697.ref007","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.3390\/ijerph17113797","article-title":"Preventing Harmful Internet Use-Related Addiction Problems in Europe: A Literature Review and Policy Options.","volume":"17","author":"O Lopez-Fernandez","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"pone.0304697.ref008","first-page":"249","article-title":"Prevalence, correlates, psychiatric comorbidities, and suicidality in a community population with problematic","volume":"244","author":"BS Kim","year":"2016","journal-title":"Internet use. 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Legleye","year":"2018","journal-title":"Int J Methods Psychiatr Res"},{"issue":"6","key":"pone.0304697.ref030","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/j.1360-0443.2007.02114.x","article-title":"Validation of the alcohol, smoking and substance involvement screening test (ASSIST).","volume":"103","author":"R Humeniuk","year":"2008","journal-title":"Addiction"},{"key":"pone.0304697.ref031","author":"Canadian Internet Use Survey (CIUS)","year":"2023","journal-title":"Statistics Canada"},{"key":"pone.0304697.ref032","author":"M Dufour","year":"2019","journal-title":"D\u00e9pistage\/\u00c9valuation du Besoin d\u2019Aide\u2013Internet (D\u00c9BA-Internet)"},{"issue":"3","key":"pone.0304697.ref033","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/MLR.0b013e318160d093","article-title":"Validation and Standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the General Population.","volume":"46","author":"B L\u00f6we","year":"2008","journal-title":"Med Care."},{"issue":"5","key":"pone.0304697.ref034","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.genhosppsych.2013.04.006","article-title":"Standardization of the depression screener Patient Health Questionnaire (PHQ-9) in the general population.","volume":"35","author":"RD Kocalevent","year":"2013","journal-title":"Gen Hosp Psychiatry."},{"key":"pone.0304697.ref035","year":"2023","journal-title":"Mental Health and Access to Care Survey (MHACS)Statistics Canada"},{"issue":"2\u20133","key":"pone.0304697.ref036","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.drugalcdep.2010.08.011","article-title":"Psychometric properties of the Cannabis Abuse Screening Test (CAST) in a French sample of adolescents.","volume":"113","author":"S Legleye","year":"2011","journal-title":"Drug Alcohol Depend"},{"issue":"6","key":"pone.0304697.ref037","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1089\/cpb.2007.0249","article-title":"French Validation of the Internet Addiction Test.","volume":"11","author":"Y Khazaal","year":"2008","journal-title":"Cyberpsychol Behav"},{"key":"pone.0304697.ref038","unstructured":"Pfizer. Patient Health Questionnaire Screeners (PHQ-9 and GAD-7) [Internet]. [cited 2024 Mar 12]. Available from: https:\/\/www.phqscreeners.com\/index.html."},{"issue":"1","key":"pone.0304697.ref039","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1747-597X-7-14","article-title":"Validation of the French version of the alcohol, smoking and substance involvement screening test (ASSIST) in the elderly.","volume":"7","author":"R Khan","year":"2012","journal-title":"Subst Abuse Treat Prev Policy"},{"issue":"1","key":"pone.0304697.ref040","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1751-0473-3-17","article-title":"Purposeful selection of variables in logistic regression.","volume":"3","author":"Z Bursac","year":"2008","journal-title":"Source Code Biol Med."},{"issue":"4","key":"pone.0304697.ref041","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4","article-title":"Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors.","volume":"15","author":"FE Harrell","year":"1996","journal-title":"Stat Med."},{"issue":"2","key":"pone.0304697.ref042","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/qhc.11.2.148","article-title":"Qualitative methods in research on healthcare quality.","volume":"11","author":"C Pope","year":"2002","journal-title":"Qual Saf Health Care."},{"issue":"1","key":"pone.0304697.ref043","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/nur.20362","article-title":"What\u2019s in a name? Qualitative description revisited.","volume":"33","author":"M. Sandelowski","year":"2010","journal-title":"Res Nurs Health."},{"key":"pone.0304697.ref044","first-page":"380","volume-title":"Qualitative data analysis: a methods sourcebook","author":"MB Miles","year":"2020","edition":"4"},{"issue":"6pt2","key":"pone.0304697.ref045","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1111\/1475-6773.12117","article-title":"Achieving Integration in Mixed Methods Designs-Principles and Practices.","volume":"48","author":"MD Fetters","year":"2013","journal-title":"Health Serv Res."},{"issue":"4","key":"pone.0304697.ref046","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1111\/j.1365-2929.2006.02418.x","article-title":"The qualitative research interview.","volume":"40","author":"B DiCicco-Bloom","year":"2006","journal-title":"Med Educ."},{"key":"pone.0304697.ref047","article-title":"Are We There Yet? 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