{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:38:25Z","timestamp":1792802305896,"version":"4.5.0"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Natural Science Foundation of Shanxi Province of China","award":["20210302124299"],"award-info":[{"award-number":["20210302124299"]}]},{"name":"Natural Science Foundation of Shanxi Province of China","award":["202303021221180"],"award-info":[{"award-number":["202303021221180"]}]},{"name":"Academic technology leader program of Changzhi Medical College","award":["XS202103"],"award-info":[{"award-number":["XS202103"]}],"id":[{"id":"https:\/\/ror.org\/0340wst14","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    <jats:italic>Babesia<\/jats:italic>\n                    is a tick-transmitted parasite that infects wild and domestic animals, causes babesiosis in humans, and is an increasing public health concern. Here, we investigated the prevalence and molecular characteristics of\n                    <jats:italic>Babesia<\/jats:italic>\n                    infections in the rodents in Southeastern Shanxi, China. Small rodents were captured, and the liver and spleen tissues were used for\n                    <jats:italic>Babesia<\/jats:italic>\n                    detection using traditional PCR and sequencing of the partial 18S rRNA gene. The analysis revealed that 27 of 252 small rodents were positive for\n                    <jats:italic>Babesia<\/jats:italic>\n                    , with an infection rate of 10.71%. The infection rates in different sexes and rodent tissues were not statistically different, but those in different rodent species, habitats, and sampling sites were statistically different. The highest risk of\n                    <jats:italic>Babesia<\/jats:italic>\n                    infection was observed in\n                    <jats:italic>Niviventer confucianus<\/jats:italic>\n                    captured from the forests in Huguan County. Forty-three sequences from 27 small rodents positive for\n                    <jats:italic>Babesia<\/jats:italic>\n                    infection were identified as\n                    <jats:italic>Babesia microti<\/jats:italic>\n                    , including 42 sequences from 26\n                    <jats:italic>N<\/jats:italic>\n                    .\n                    <jats:italic>confucianus<\/jats:italic>\n                    , and one sequence from\n                    <jats:italic>Apodemus agrarius<\/jats:italic>\n                    . Phylogenetic analysis showed that all sequences were clustered together and had the closest genetic relationship with\n                    <jats:italic>Babesia microti<\/jats:italic>\n                    strains isolated from\n                    <jats:italic>Rattus losea<\/jats:italic>\n                    and\n                    <jats:italic>N<\/jats:italic>\n                    .\n                    <jats:italic>confucianus<\/jats:italic>\n                    in China, and belonged to the Kobe-type, which is pathogenic to humans. Compared to other Kobe-type strains based on the nearly complete 18S rRNA gene, the sequences obtained in this study showed the difference by 1\u20133 bp. Overall, a high prevalence of\n                    <jats:italic>Babesia microti<\/jats:italic>\n                    infection was observed in small rodents in Southeastern Shanxi, China, which could benefit us to take the implementation of relevant prevention and control measures in this area.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0306181","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T13:28:40Z","timestamp":1720013320000},"page":"e0306181","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence and molecular detection of Babesia microti in rodents in Southeastern Shanxi, China"],"prefix":"10.1371","volume":"19","author":[{"given":"Yiping","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrong","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaxiang","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9537-6577","authenticated-orcid":true,"given":"Juan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,7,3]]},"reference":[{"issue":"2","key":"pone.0306181.ref001","doi-asserted-by":"crossref","first-page":"627","DOI":"10.20506\/rst.34.2.2385","article-title":"Babesiosis","volume":"34","author":"F Beugnet","year":"2015","journal-title":"Rev Sci Tech"},{"issue":"8","key":"pone.0306181.ref002","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1016\/j.meegid.2012.07.004","article-title":"Babesia: a world emerging","volume":"12","author":"L Schnittger","year":"2012","journal-title":"Infect Genet Evol"},{"issue":"1\u20132","key":"pone.0306181.ref003","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.vetpar.2006.01.035","article-title":"Babesia\u2014a historical overview","volume":"138","author":"G. 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