{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:08:20Z","timestamp":1783652900988,"version":"3.55.0"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T00:00:00Z","timestamp":1724371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Preventing Atherosclerotic Cardiovascular Diseases (ASCVD) can best be achieved by promoting a healthy lifestyle through improvements in diet, physical activity, and avoidance of tobacco use and exposure to second-hand smoke. The study aimed to determine the association between physical activity as well as obesity and the risk of atherosclerotic cardiovascular diseases among patients with hypertension and diabetes attending Irrua Specialist Teaching Hospital (ISTH), Irrua, Nigeria.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methodology<\/jats:title>\n<jats:p>The research was a descriptive, cross-sectional study of 394 systematically selected consenting patients with hypertension and diabetes presenting to a teaching hospital in Irrua, Edo State, Nigeria. The Cardiovascular risk assessment was determined using the Framingham 10year Risk of General Cardiovascular Disease. Anthropometric assessment, blood pressure and blood glucose were determined. Data was collected with a semi-structured questionnaire and analysed with Stata version 16. Chi square and logistic regression was used to test for association and significance level was set at p = 0.05.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The study included 394 participants with a mean age of 54\u00b115.47years. Respondents were mostly females (55.3%), physically inactive (70.3%), overweight (42.4%) and had a high risk (41.8%) of developing CVD in 10 years using Framingham categorisation. There was a significant association between physical activity (P&lt;0.01; OR 2.45; CI: 1.53\u20133.92), obesity (P&lt;0.01; OR 2.52; CI: 1.64\u20133.86) and risk of developing CVD.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The study found a statistically significant relationship between physical inactivity, obesity, and the risk of atherosclerotic cardiovascular diseases. Increasing physical activity levels need to be a top priority at all levels of healthcare as well as the general population.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0307526","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T17:33:11Z","timestamp":1724434391000},"page":"e0307526","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Physical activity, obesity and risk of atherosclerotic cardiovascular diseases among patients with hypertension and diabetes attending a teaching hospital in Edo State, Nigeria"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5301-1983","authenticated-orcid":true,"given":"Tijani Idris Ahmad","family":"Oseni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulaiman Dazumi","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline Etuajie","family":"Eromon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neba Francis","family":"Fuh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac Newton","family":"Omoregbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"issue":"5","key":"pone.0307526.ref001","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.arcmed.2015.06.006","article-title":"Global overview of the epidemiology of atherosclerotic cardiovascular disease","volume":"46","author":"S Barquera","year":"2015","journal-title":"Archives of medical research"},{"issue":"6","key":"pone.0307526.ref002","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.3390\/ijms23063346","article-title":"Pathophysiology of atherosclerosis","volume":"23","author":"S Jebari-Benslaiman","year":"2022","journal-title":"International journal of molecular sciences"},{"issue":"1","key":"pone.0307526.ref003","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/njc.njc_33_19","article-title":"Cardiovascular diseases in Nigeria: What has happened in the past 20 years?.","volume":"17","author":"SO Ike","year":"2020","journal-title":"Nigerian Journal of Cardiology"},{"issue":"2","key":"pone.0307526.ref004","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/JCN.0b013e31827db5eb","article-title":"Family history of cardiovascular disease, perceived cardiovascular disease risk, and health-related behavior: a review of the literature","volume":"29","author":"CC Imes","year":"2014","journal-title":"Journal of cardiovascular nursing"},{"issue":"22","key":"pone.0307526.ref005","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1161\/CIRCULATIONAHA.118.037367","article-title":"Tackling the growing burden of cardiovascular diseases in sub-Saharan Africa: need for dietary guidelines","volume":"138","author":"AK Amegah","year":"2018","journal-title":"Circulation"},{"issue":"2","key":"pone.0307526.ref006","doi-asserted-by":"crossref","first-page":"71","DOI":"10.4103\/njc.njc_23_17","article-title":"Rising trend of cardiovascular diseases among South-Western Nigerian female patients","volume":"14","author":"AD Adedapo","year":"2017","journal-title":"Nigerian Journal of Cardiology"},{"issue":"07","key":"pone.0307526.ref007","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4236\/wjcd.2020.107040","article-title":"Cardiovascular risk factors in south-eastern Nigeria: a community based survey.","volume":"10","author":"CO Eze","year":"2020","journal-title":"World Journal of Cardiovascular Diseases"},{"key":"pone.0307526.ref008","doi-asserted-by":"crossref","first-page":"959285","DOI":"10.3389\/fcvm.2022.959285","article-title":"Hypertension as a risk factor for atherosclerosis: Cardiovascular risk assessment.","volume":"9","author":"AV Poznyak","year":"2022","journal-title":"Frontiers in Cardiovascular Medicine"},{"issue":"3","key":"pone.0307526.ref009","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3126\/jnps.v41i3.36244","article-title":"Relationship Between Microalbuminuria and Risk Factors for Cardiovascular Diseases Among Secondary School Student in Ilorin","volume":"41","author":"KO Alabi","year":"2021","journal-title":"Nigeria. 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