{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:02:35Z","timestamp":1787022155757,"version":"build-2736575974"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Preeclampsia and eclampsia are among the leading direct causes of maternal death and morbidity worldwide. Up to 34% of maternal deaths in Tanzania are due to preeclampsia\/ eclampsia. Magnesium sulfate is recommended for preventing and treating convulsions in women with Preeclampsia or eclampsia. However, evidence suggests limited knowledge of its dosage and proper toxicity assessment after administration among health care providers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Aim of the study<\/jats:title>\n                    <jats:p>\n                      This study explored nurse-midwives\u2019 perspectives on providing MgSO\n                      <jats:sub>4<\/jats:sub>\n                      to patients with preeclampsia or eclampsia in Tanzania.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A descriptive exploratory qualitative study using in-depth interviews was conducted to understand nurse-midwives\u2019 perspectives on providing magnesium sulfate to patients with PE\/E. Nineteen nurse-midwives were interviewed from three hospitals in the Dar es Salaam region. We used a semi-structured interview guide in Kiswahili language to collect data. All interviews were digitally recorded and transcribed verbatim. We analyzed data using inductive content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study revealed that nurse-midwives provide magnesium sulfate to save the lives of women and their unborn children. Nurse-midwives reasoned that confidence in their skill enhances provision of magnesium sulfate. However, they were concerned about its effect on the progress of labour. Ineffective use of magnesium sulfate emerged from inadequate training, an unsupportive work environment, and underutilization of the existing guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec005\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nurse-midwives have clear drive to provide magnesium sulfate to women with preeclampsia or eclampsia. However, inadequate training, underutilization of guidelines and unsupportive work environment lead to ineffective use of magnesium sulfate. Targeted practical training should be emphasized for nurse-midwives mastery of clinical competencies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0308382","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T13:30:39Z","timestamp":1723037439000},"page":"e0308382","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Perspectives of providing magnesium sulfate to patients with preeclampsia and eclampsia: A qualitative study amongst nurse-midwives in Dar es Salaam, Tanzania"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6678-5022","authenticated-orcid":true,"given":"Victor Z.","family":"Chikwala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes F.","family":"Massae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella E.","family":"Mushy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith A. M.","family":"Tarimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"issue":"1","key":"pone.0308382.ref001","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/HYPERTENSIONAHA.117.10803","article-title":"Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practice","volume":"72","author":"M a Brown","year":"2018","journal-title":"Hypertension"},{"issue":"2006","key":"pone.0308382.ref002","first-page":"1","article-title":"Patterns and causes of hospital maternal mortality in.","volume":"24","author":"VM Bwana","year":"2019","journal-title":"PLoS One."},{"key":"pone.0308382.ref003","first-page":"353","author":"D. Press","year":"2017","journal-title":"Severe preeclampsia and eclampsia: incidence, complications, and perinatal outcomes at a low-resource setting, Mpilo Central Hospital,."},{"issue":"6 June","key":"pone.0308382.ref004","first-page":"1","article-title":"Clinical presentation and outcomes of preeclampsia and eclampsia at a national hospital, Kenya: A retrospective cohort study.","volume":"15","author":"C Ndwiga","year":"2020","journal-title":"PLoS One."},{"issue":"Suppl 1","key":"pone.0308382.ref005","first-page":"3","article-title":"A literature review and best practice advice for second and third trimester risk stratification, monitoring, and management of pre- - eclampsia Compiled by the Pregnancy and Non- - Communicable Diseases Committee of FIGO (the International Federation o.","volume":"154","author":"LC Poon","year":"2021"},{"key":"pone.0308382.ref006","author":"MoHCDGEC","year":"2021","journal-title":"STANDARD TREATMENT GUIDELINES AND NATIONAL ESSENTIAL MEDICINES LIST FOR STANDARD TREATMENT GUIDELINES AND NATIONAL ESSENTIAL MEDICINES LIST FOR"},{"issue":"2","key":"pone.0308382.ref007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2017-020608","article-title":"Health facility service availability and readiness to provide basic emergency obstetric and newborn care in a low-resource setting: Evidence from a Tanzania National Survey","volume":"9","author":"D Bintabara","year":"2019","journal-title":"BMJ Open"},{"issue":"1","key":"pone.0308382.ref008","first-page":"33","volume":"4","author":"JA Angelina","year":"2020","journal-title":"Knowledge on Prevention and Management of Preeclampsia and Eclampsia"},{"issue":"5","key":"pone.0308382.ref009","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1177\/1744987119880234","article-title":"An overview of the qualitative descriptive design within nursing research.","volume":"25","author":"L Doyle","year":"2020","journal-title":"J Res Nurs"},{"key":"pone.0308382.ref010","first-page":"1","article-title":"The United Republic of Tanzania Ministry of Health and Social Welfare Staffing Levels for Ministry of Health and Social Welfare Departments, Health Service Facilities, Health Training Institutions and Agencies 2014\u20132019 Revised 6 Samora Machel Avenue, 114.","author":"MoHCDGEC","year":"2019","journal-title":"Minist Heal Soc Welfaire Dar es salaam, Tanzania."},{"key":"pone.0308382.ref011","doi-asserted-by":"crossref","first-page":"114523","DOI":"10.1016\/j.socscimed.2021.114523","article-title":"Sample sizes for saturation in qualitative research: A systematic review of empirical tests","volume":"292","author":"M Hennink","year":"2022","journal-title":"Soc Sci Med [Internet]."},{"key":"pone.0308382.ref012","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.nedt.2003.10.001","article-title":"Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness.","volume":"24","author":"UH Graneheim","year":"2004","journal-title":"Nurse Educ Today"},{"key":"pone.0308382.ref013","volume-title":"Managing Complications in Pregnancy and Childbirth: a guide for midwives and doctors [Internet].","author":"WHO, UNICEF U","year":"2017","edition":"2"},{"issue":"October 2021","key":"pone.0308382.ref014","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.preghy.2021.09.008","article-title":"The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice.","volume":"27","author":"LA Magee","year":"2022","journal-title":"Pregnancy Hypertens [Internet]."},{"issue":"2","key":"pone.0308382.ref015","doi-asserted-by":"crossref","first-page":"569","DOI":"10.21608\/mnj.2022.295624","article-title":"Evaluate Magnesium Sulfate Administration Practice to Eclamptic Mothers.","volume":"9","author":"nafesa Rakha","year":"2022","journal-title":"Mansoura Nurs J"},{"issue":"20","key":"pone.0308382.ref016","doi-asserted-by":"crossref","first-page":"3885","DOI":"10.1080\/14767058.2020.1843017","article-title":"Provider practices for the prevention of eclampsia and attitudes toward magnesium sulfate: results of a nationwide survey","volume":"35","author":"E Yoselevsky","year":"2022","journal-title":"J Matern Neonatal Med [Internet]."},{"issue":"Suppl 1","key":"pone.0308382.ref017","article-title":"Availability and use of magnesium sulphate at health care facilities in two selected districts of North Karnataka, India.","volume":"15","author":"G Katageri","year":"2018","journal-title":"Reprod Health."},{"issue":"3","key":"pone.0308382.ref018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0172602","article-title":"Obstetrician\u2019s risk perception on the prescription of magnesium sulfate in severe preeclampsia and eclampsia: A qualitative study in Brazil.","volume":"12","author":"FA Lotufo","year":"2017","journal-title":"PLoS One"},{"issue":"3","key":"pone.0308382.ref019","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/1471-0528.16913","article-title":"Factors affecting use of magnesium sulphate for pre-eclampsia or eclampsia: a qualitative evidence synthesis.","volume":"129","author":"KE Eddy","year":"2022","journal-title":"BJOG An Int J Obstet Gynaecol"},{"key":"pone.0308382.ref020","first-page":"187","article-title":"Perception of Midwives Towards Magnesium Sulfate Use at Chatinkha Maternity Wing in Blantyre, Malawi: A Qualitative Study.","author":"LK Phiri","year":"2020"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0308382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T13:31:15Z","timestamp":1723037475000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0308382"}},"subtitle":[],"editor":[{"given":"Ayodeji Babatunde","family":"Oginni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,8,7]]},"references-count":20,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0308382","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,7]]}}}