{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:08:58Z","timestamp":1740146938629,"version":"3.37.3"},"reference-count":42,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T00:00:00Z","timestamp":1723680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007834","name":"Natural Science Foundation of Ningbo Municipality","doi-asserted-by":"publisher","award":["2021J281"],"award-info":[{"award-number":["2021J281"]}],"id":[{"id":"10.13039\/100007834","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013067","name":"Key Supported Discipline of Guizhou Provence","doi-asserted-by":"publisher","award":["2022-P09"],"award-info":[{"award-number":["2022-P09"]}],"id":[{"id":"10.13039\/501100013067","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ningbo Key Clinical Speciality Construction Project","award":["2023-BZZ"],"award-info":[{"award-number":["2023-BZZ"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Nocturia, a prevalent chronic condition, impacts individuals\u2019 quality of life but remains underexplored. This study aimed to assess the association between serum albumin levels and nocturia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Based on the analysis of the National Health and Nutrition Examination Survey (NHANES) database (2005\u20132012), our study included a total of 6345 adults (\u226520 years old). Nocturia was defined as \u22652 nocturnal voiding episodes. Logistic regression and smooth curve fitting analyzed the linear and nonlinear correlations between serum albumin and nocturia, with subgroup analysis.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Among 6345 participants, 1821 (28.7%) experienced nocturia. Logistic regression analysis revealed a linear negative correlation between serum albumin and nocturia risk (OR = 0.9549, 95% CI = 0.9280 ~ 0.9827, P = 0.002). Even after quartile division of serum albumin concentration, this correlation persisted within each group, and a smooth curve fitting validated the nonlinear negative correlation between the two. Subgroup analysis further demonstrated significant impacts of body mass index (BMI), alcohol consumption, and age on this association.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>This cross-sectional study indicated that higher serum albumin levels were associated with a reduced risk of nocturia in U.S. adults aged 20 and older, highlighting the importance of serum albumin in the prevention and treatment of nocturia and providing clinical guidance.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0308980","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T17:37:55Z","timestamp":1723743475000},"page":"e0308980","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between nocturia and serum albumin in the U.S. adults from NHANES 2005\u20132012"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2919-3654","authenticated-orcid":true,"given":"Yangtao","family":"Jia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangzheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinke","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huimin","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,8,15]]},"reference":[{"issue":"10","key":"pone.0308980.ref001","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrurol.2016.134","article-title":"Nocturia: aetiology and treatment in adults","volume":"13","author":"H Dani","year":"2016","journal-title":"Nat Rev Urol"},{"issue":"3","key":"pone.0308980.ref002","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.eururo.2009.03.081","article-title":"Editorial comment on: Nocturia frequency, bother, and quality of life: how often is too often? 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