{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:16:16Z","timestamp":1788916576204,"version":"build-2803163510"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The combination of an optical probe and single-drop direct immersion microextraction (DI-SDME-OP) was used for the preconcentration and subsequent spectrophotometric determination of rhodamine 6G (Rh6G). The developed method is based on the formation of an ionic associate between Rh6G and picric acid at pH 3.0 and its extraction with amyl acetate. A microdrop of the organic phase was stably placed in the hole of an optical probe immersed in the sample solution. The absorbance of the extraction phase was monitored at 534 nm. The proposed method combines in a single step several stages of the analytical procedure, such as pre-concentration, phase separation, transfer of the extraction phase to the instrument and online measurement. The sensitivity of the proposed approach is not inferior to existing microextraction methods involving the combination of liquid-phase or solid-phase extraction with spectrophotometry or HPLC with a UV-Vis detector. The evaluation of the greenness of the developed method carried out by the AGREE method (0.58 points) showed that it outperforms other similar existing techniques using this parameter. The calibration plot for the determination of Rh6G by the DI-SDME-OP method was linear over the range of 10\u2013500 nM with a correlation coefficient of 0.9956. The limit of detection was 3.4 nM. The accuracy and applicability of the method were evaluated by the determination of Rh6G in natural waters and lipstick.<\/jats:p>","DOI":"10.1371\/journal.pone.0309121","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T17:27:08Z","timestamp":1724088428000},"page":"e0309121","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Determination of Rhodamine 6G with direct immersion single-drop microextraction combined with an optical probe"],"prefix":"10.1371","volume":"19","author":[{"given":"Arina","family":"Skok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0148-7845","authenticated-orcid":true,"given":"Andriy","family":"Vishnikin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaroslav","family":"Bazel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1n","family":"Toth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"key":"pone.0309121.ref001","doi-asserted-by":"crossref","first-page":"137222","DOI":"10.1016\/j.scitotenv.2020.137222","article-title":"Synthetic organic dyes as contaminants of the aquatic environment and their implications for ecosystems: A review","volume":"717","author":"A Tkaczyk","year":"2020","journal-title":"Sci. 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Ophtalmol. Vis. Sci"},{"key":"pone.0309121.ref007","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.talanta.2015.02.051","article-title":"Optimization of magnetic stirring assisted dispersive liquid\u2013liquid microextraction of rhodamine B and rhodamine 6G by response surface methodology: Application in water samples, soft drink, and cosmetic products","volume":"139","author":"E Ranjbari","year":"2015","journal-title":"Talanta"},{"key":"pone.0309121.ref008","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0960-8524(00)00080-8","article-title":"Remediation of dyes in textile eluent: a critical review on current treatment technologies with a proposed alternative","volume":"77","author":"T Robinson","year":"2001","journal-title":"Bioresour. 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Acta A"},{"key":"pone.0309121.ref011","doi-asserted-by":"crossref","first-page":"4256","DOI":"10.1002\/jssc.201700659","article-title":"Polypyrrole-magnetite dispersive micro-solid-phase extraction combined with ultraviolet-visible spectrophotometry for the determination of rhodamine 6G and crystal violet in textile wastewater","volume":"40","author":"AF Kamaruddin","year":"2017","journal-title":"J. Sep. Sci"},{"key":"pone.0309121.ref012","first-page":"1","article-title":"Trace determination of Rhodamine B and Rhodamine 6G dyes in aqueous samples by solid-phase extraction and high-performance liquid chromatography coupled with fluorescence detection","volume":"59","author":"TL Chiang","year":"2011","journal-title":"J. Chin. Chem. Soc"},{"key":"pone.0309121.ref013","doi-asserted-by":"crossref","first-page":"136665","DOI":"10.1016\/j.foodchem.2023.136665","article-title":"Simultaneous qualitative and quantitative determination of 104 fat-soluble synthetic dyes in foods using disperse solid-phase extraction and UHPLC-Q-Orbitrap HRMS analysis","volume":"427","author":"P Qi","year":"2023","journal-title":"Food Chem"},{"key":"pone.0309121.ref014","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1002\/jssc.201600261","article-title":"Computational design and fabrication of core-shell magnetic molecularly imprinted polymer for dispersive micro-solid-phase extraction coupled with high-performance liquid chromatography for the determination of rhodamine 6G","volume":"39","author":"J Xie","year":"2016","journal-title":"J. Sep. 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