{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:22:53Z","timestamp":1747196573581,"version":"3.40.5"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Internacional del Ecuador","award":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"],"award-info":[{"award-number":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"]}]},{"name":"Corporaci\u00f3n Ecuatoriana para el Desarrollo de la Investigaci\u00f3n y Academia","award":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"],"award-info":[{"award-number":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"]}]},{"name":"Universidad Internacional del Ecuador","award":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"],"award-info":[{"award-number":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"]}]},{"name":"Universidad Internacional del Ecuador","award":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"],"award-info":[{"award-number":["UIDE-DGIP-MAT-PROY-20-003; 21-007; 21-008"]}]},{"name":"Corporaci\u00f3n Ecuatoriana para el Desarrollo de la Investigaci\u00f3n y Academia","award":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"],"award-info":[{"award-number":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"]}]},{"name":"Corporaci\u00f3n Ecuatoriana para el Desarrollo de la Investigaci\u00f3n y Academia","award":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"],"award-info":[{"award-number":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"]}]},{"name":"Corporaci\u00f3n Ecuatoriana para el Desarrollo de la Investigaci\u00f3n y Academia","award":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"],"award-info":[{"award-number":["CEPRA XVI-2022-17 ANTICUERPOS IGG IGA"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>The COVID-19 pandemic has caused over 68.7 million infections and 1.35 million deaths in South America. There are limited data on SARS-CoV-2 seropositivity and its determinants from Andean countries prior to mass vaccinations against COVID-19.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To estimate SARS-CoV-2 seropositivity and its determinants before vaccination in occupational groups of adults presumed to have different levels of exposure and associations with potential symptomatology.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We measured seropositivity of anti-SARS-CoV-2 IgG antibodies in a cross-sectional study of vaccine-na\u00efve adults aged 18 years and older, recruited within three occupational risk groups (defined as low [LR], moderate [MR], and high [HR]) between January and September 2021 in two Andean cities in Ecuador. Associations with risk factors were estimated using logistic regression.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>In a sample of 882 adults, IgG seropositivity for the three different occupational risk groups was 39.9% (CI 95% 35.3\u201344.6), 74.6% (CI 95% 66.4\u201381.4), and 39.0% (CI 95% 34.0\u201344.4) for the HR, MR, and LR groups, respectively. History of an illness with loss of taste and\/or smell was significantly associated with seropositivity in all occupational groups, with adjusted ORs of 14.31 (95%CI, 5.83\u201335.12; p&lt;0.001), 14.34 (95%CI 3.01\u201368.42; p&lt;0.001), and 8.79 (95%CI 2.69\u201328.72; p&lt;0.001), for the HR, MR, and LR groups, respectively; while fever was significant for the LR group with an adjusted OR of 1.24 (95%CI, 1.11\u20134.57; p = 0.025) and myalgia for the HR group with an adjusted OR of 2.07 (95%CI, 1.13\u20133.81; p = 0.019).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Notable proportions of seropositivity were seen in all occupational groups between January and September 2021 prior to mass vaccination. Loss of taste and\/or smell was strongly associated with presence of anti-SARS-CoV-2 IgG antibodies irrespective of presumed occupational exposure risk.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0309466","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T18:17:22Z","timestamp":1724955442000},"page":"e0309466","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["COVID-19 IgG seropositivity and its determinants in occupational groups of varying infection risks in two Andean cities of Ecuador before mass vaccination"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8130-6460","authenticated-orcid":true,"given":"Jose E.","family":"Leon-Rojas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Arias-Erazo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0666-177X","authenticated-orcid":true,"given":"Patricia","family":"Jim\u00e9nez-Arias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5896-605X","authenticated-orcid":true,"given":"Ricardo","family":"Recalde-Navarrete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"Guevara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josefina","family":"Coloma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2637-1259","authenticated-orcid":true,"given":"Irina","family":"Chis Ster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Romero-Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the Seroprevalence ECU-Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"journal-title":"COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University.","author":"University JH","key":"pone.0309466.ref001"},{"key":"pone.0309466.ref002","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s40001-022-00710-2","article-title":"SARS-CoV-2 seroprevalence around the world: an updated systematic review and meta-analysis","volume":"27","author":"M Azami","year":"2022","journal-title":"Eur J Med Res"},{"key":"pone.0309466.ref003","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1093\/cid\/ciaa523","article-title":"Early Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Antibodies as a Serologic Marker of Infection in Patients With Coronavirus Disease 2019","volume":"71","author":"Z Rongqing","year":"2020","journal-title":"Clinical Infectious Diseases"},{"key":"pone.0309466.ref004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ajcp\/aqaa082","article-title":"Antibody Testing for COVID-19","volume":"154","author":"G Mathur","year":"2020","journal-title":"Am J Clin Pathol"},{"key":"pone.0309466.ref005","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jinf.2020.04.031","article-title":"The SARS-CoV-2 seroprevalence is the key factor for deconfinement in France.","volume":"81","author":"C Dimeglio","year":"2020","journal-title":"Journal of Infection"},{"key":"pone.0309466.ref006","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00941-20","article-title":"Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence in Boise, Idaho","volume":"58","author":"A Bryan","year":"2020","journal-title":"J Clin Microbiol"},{"key":"pone.0309466.ref007","doi-asserted-by":"crossref","first-page":"e0263679","DOI":"10.1371\/journal.pone.0263679","article-title":"SARS-CoV-2 seroprevalence in the city of Puerto Madryn: Underdiagnosis and relevance of children in the pandemic.","volume":"17","author":"D Schonfeld","year":"2022","journal-title":"PLoS One."},{"key":"pone.0309466.ref008","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s12931-022-02096-5","article-title":"Seroprevalence and dynamics of anti-SARS-CoV-2 antibodies: a longitudinal study based on patients with underlying diseases in Wuhan.","volume":"23","author":"J Yang","year":"2022","journal-title":"Respir Res"},{"key":"pone.0309466.ref009","doi-asserted-by":"crossref","first-page":"100195","DOI":"10.1016\/j.lana.2022.100195","article-title":"Seroprevalence of anti-SARS-CoV-2 antibodies in Colombia, 2020: A population-based study","volume":"9","author":"M Mercado-Reyes","year":"2022","journal-title":"The Lancet Regional Health\u2014Americas"},{"key":"pone.0309466.ref010","doi-asserted-by":"crossref","first-page":"e12552","DOI":"10.7717\/peerj.12552","article-title":"Seroprevalence and lethality by SARS-CoV-2 in indigenous populations of Latin America and the Caribbean: a systematic review.","volume":"9","author":"A Hern\u00e1ndez-V\u00e1squez","year":"2021","journal-title":"PeerJ"},{"key":"pone.0309466.ref011","doi-asserted-by":"crossref","first-page":"100016","DOI":"10.1016\/j.clinsp.2022.100016","article-title":"Increasing rate of anti-SARS-CoV-2 antibodies between the first and second waves of COVID-19 in S\u00e3o Paulo, Brazil: A cross-sectional blood donors-based study","volume":"77","author":"N Moya Rios do Vale","year":"2022","journal-title":"Clinics"},{"key":"pone.0309466.ref012","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1093\/cid\/ciaa1055","article-title":"SARS-CoV-2 in Rural Latin America. A Population-based Study in Coastal Ecuador","volume":"73","author":"OH Del Brutto","year":"2021","journal-title":"Clinical Infectious Diseases"},{"key":"pone.0309466.ref013","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/20477724.2020.1826152","article-title":"Late incidence of SARS-CoV-2 infection in a highly-endemic remote rural village. A prospective population-based cohort study.","volume":"114","author":"OH Del Brutto","year":"2020","journal-title":"Pathog Glob Health"},{"key":"pone.0309466.ref014","doi-asserted-by":"crossref","first-page":"215013272110477","DOI":"10.1177\/21501327211047781","article-title":"Body Composition in Community-Dwelling Older Adults Before and After SARS-CoV-2 Infection: A Longitudinal Prospective Study in a Rural Village Struck by the Pandemic.","volume":"12","author":"OH Del Brutto","year":"2021","journal-title":"J Prim Care Community Health."},{"key":"pone.0309466.ref015","doi-asserted-by":"crossref","first-page":"215013272110549","DOI":"10.1177\/21501327211054989","article-title":"Factors Associated With a Persistent Seronegative Status 1\u2009Year After a SARS-CoV-2 Massive Infection Outbreak in Community Dwellers Living in Rural Ecuador: A Prospective Population-based Study.","volume":"12","author":"OH Del Brutto","year":"2021","journal-title":"J Prim Care Community Health."},{"key":"pone.0309466.ref016","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s10900-020-00887-9","article-title":"Social Determinants of Health and Risk of SARS-CoV-2 Infection in Community-Dwelling Older Adults Living in a Rural Latin American Setting.","volume":"46","author":"OH Del Brutto","year":"2021","journal-title":"J Community Health."},{"key":"pone.0309466.ref017","doi-asserted-by":"crossref","first-page":"215013192110706","DOI":"10.1177\/21501319211070685","article-title":"Risk for Subsequent SARS-CoV-2 Infection and Severe COVID-19 Among Community-Dwellers With Pre-Existing Cervicocephalic Atherosclerosis: A Population-Based Study.","volume":"13","author":"OH Del Brutto","year":"2022","journal-title":"J Prim Care Community Health"},{"key":"pone.0309466.ref018","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.3390\/ijerph18094657","article-title":"Seroprevalence of SARS-CoV-2 Infection and Adherence to Preventive Measures in Cuenca, Ecuador, October 2020, a Cross-Sectional Study.","volume":"18","author":"D Acurio-P\u00e1ez","year":"2021","journal-title":"Int J Environ Res Public Health."},{"key":"pone.0309466.ref019","article-title":"Sustained COVID-19 community transmission and potential super spreading events at neglected afro-ecuadorian communities assessed by massive RT-qPCR and serological testing of community dwelling population.","volume":"9","author":"AP Vallejo-Janeta","year":"2022","journal-title":"Front Med (Lausanne)."},{"key":"pone.0309466.ref020","doi-asserted-by":"crossref","first-page":"e1004107","DOI":"10.1371\/journal.pmed.1004107","article-title":"Global SARS-CoV-2 seroprevalence from January 2020 to April 2022: A systematic review and meta-analysis of standardized population-based studies.","volume":"19","author":"I Bergeri","year":"2022","journal-title":"PLoS Med."},{"key":"pone.0309466.ref021","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.ijid.2021.07.022","article-title":"High seroprevalence for SARS-CoV-2 infection in South America, but still not enough for herd immunity!","volume":"109","author":"SF N\u00fa\u00f1ez-Zapata","year":"2021","journal-title":"International Journal of Infectious Diseases."},{"key":"pone.0309466.ref022","doi-asserted-by":"crossref","first-page":"e1508","DOI":"10.1016\/S2214-109X(21)00355-7","article-title":"High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort.","volume":"9","author":"P Lalwani","year":"2021","journal-title":"Lancet Glob Health."},{"key":"pone.0309466.ref023","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/irv.12952","article-title":"SARS\u2010CoV\u20102 infections in households in a peri\u2010urban community of Lima, Peru: A prospective cohort study.","volume":"16","author":"CF Lanata","year":"2022","journal-title":"Influenza Other Respir Viruses"},{"key":"pone.0309466.ref024","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12879-022-07045-7","article-title":"Seroprevalence, spatial distribution, and social determinants of SARS-CoV-2 in three urban centers of Chile.","volume":"22","author":"P Vial","year":"2022","journal-title":"BMC Infect Dis"},{"key":"pone.0309466.ref025","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3390\/v14020232","article-title":"High SARS-CoV-2 Prevalence among Healthcare Workers in Cochabamba, Bolivia.","volume":"14","author":"PM Saba Villarroel","year":"2022","journal-title":"Viruses"},{"key":"pone.0309466.ref026","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/jrh.12459","article-title":"Being African American and Rural: A Double Jeopardy From COVID\u201019","volume":"37","author":"L Sood","year":"2021","journal-title":"The Journal of Rural Health"},{"key":"pone.0309466.ref027","doi-asserted-by":"crossref","first-page":"4704","DOI":"10.1038\/s41467-020-18450-4","article-title":"A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity.","volume":"11","author":"AT Huang","year":"2020","journal-title":"Nat Commun."},{"key":"pone.0309466.ref028","first-page":"5","article-title":"Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward.","author":"JE Bryant","year":"2020","journal-title":"Sci Immunol."},{"key":"pone.0309466.ref029","doi-asserted-by":"crossref","first-page":"e0233588","DOI":"10.1371\/journal.pone.0233588","article-title":"Work-related COVID-19 transmission in six Asian countries\/areas: A follow-up study.","volume":"15","author":"F-Y Lan","year":"2020","journal-title":"PLoS One."},{"key":"pone.0309466.ref030","article-title":"Preval\u00eancia sorol\u00f3gica de infec\u00e7\u00e3o por SARS-CoV-2 entre trabalhadores do sistema prisional do Esp\u00edrito Santo, 2020.","volume":"31","author":"CLC Duque","year":"2022","journal-title":"Epidemiologia e Servi\u00e7os de Sa\u00fade."},{"key":"pone.0309466.ref031","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1017\/S0950268824000037","article-title":"The predictive role of symptoms in COVID-19 diagnostic models: A longitudinal insight","volume":"152","author":"O Bird","year":"2024","journal-title":"Epidemiol Infect"},{"key":"pone.0309466.ref032","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.12688\/f1000research.126577.1","article-title":"The dynamics and determinants of specific systemic and mucosal antibody responses to SARS-CoV-2 in three adult cohorts in the Ecuadorian Andes: a study protocol.","volume":"11","author":"JE Leon-Rojas","year":"2022","journal-title":"F1000Res"},{"key":"pone.0309466.ref033","doi-asserted-by":"crossref","first-page":"759","DOI":"10.15585\/mmwr.mm6924e2","article-title":"Coronavirus Disease 2019 Case Surveillance\u2014United States, January 22\u2013May 30, 2020.","volume":"69","author":"EK Stokes","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"pone.0309466.ref034","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0194599820926473","article-title":"The Prevalence of Olfactory and Gustatory Dysfunction in COVID\u201019 Patients: A Systematic Review and Meta\u2010analysis.","volume":"163","author":"JY Tong","year":"2020","journal-title":"Otolaryngology\u2013Head and Neck Surgery"},{"key":"pone.0309466.ref035","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.4269\/ajtmh.20-1420","article-title":"A Low-Cost SARS-CoV-2 rRBD ELISA to Detect Serostatus in Ecuadorian Population with COVID-19","volume":"104","author":"\u00c1 Guevara","year":"2021","journal-title":"Am J Trop Med Hyg"},{"volume-title":"Datos Epidemiol\u00f3gicos\u2013COVID-19","author":"Ministerio de Salud del Ecuador","key":"pone.0309466.ref036"},{"journal-title":"\u201cNew cases.","article-title":"WHO COVID-19 Dashboard\u2013processed by Our World in Data.","author":"Our World in Data","key":"pone.0309466.ref037"},{"key":"pone.0309466.ref038","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2022.1012434","article-title":"High rates of SARS-CoV-2 infection in funeral home workers in Ecuador: Is it an occupational risk for COVID-19?","volume":"10","author":"E Ortiz-Prado","year":"2022","journal-title":"Front Public Health."},{"key":"pone.0309466.ref039","article-title":"High SARS-CoV-2 Infection Rates Among Special Forces Police Units During the Early Phase of the COVID-19 Pandemic in Ecuador.","volume":"8","author":"E Ortiz-Prado","year":"2022","journal-title":"Front Med (Lausanne)."},{"key":"pone.0309466.ref040","doi-asserted-by":"crossref","first-page":"145225","DOI":"10.1016\/j.scitotenv.2021.145225","article-title":"High prevalence of SARS-CoV-2 infection among food delivery riders. A case study from Quito, Ecuador","volume":"770","author":"E Ortiz-Prado","year":"2021","journal-title":"Science of The Total Environment"},{"key":"pone.0309466.ref041","article-title":"High SARS-CoV-2 infection rates and viral loads in community-dwelling individuals from rural indigenous and mestizo communities from the Andes during the first wave of the COVID-19 pandemic in Ecuador.","volume":"10","author":"D Morales-Jad\u00e1n","year":"2023","journal-title":"Front Med (Lausanne)."},{"key":"pone.0309466.ref042","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4269\/ajtmh.21-0582","article-title":"COVID-19 Community Transmission and Super Spreaders in Rural Villages from Manabi Province in the Coastal Region of Ecuador Assessed by Massive Testing of Community-Dwelling Population","volume":"106","author":"MB Rodriguez-Paredes","year":"2022","journal-title":"Am J Trop Med Hyg"},{"key":"pone.0309466.ref043","doi-asserted-by":"crossref","first-page":"478","DOI":"10.2471\/BLT.20.283028","article-title":"COVID-19 outbreaks among isolated Amazonian indigenous people, Ecuador","volume":"99","author":"A Henriquez-Trujillo","year":"2021","journal-title":"Bull World Health Organ"},{"key":"pone.0309466.ref044","first-page":"7643","article-title":"Massive testing in the Galapagos Islands and low positivity rate to control SARS-CoV-2 spread during the first semester of the COVID-19 pandemic: a story of success for Ecuador and South America.","volume":"23","author":"Morales-Jadan Vallejo-Janeta","year":"2023","journal-title":"Rural Remote Health"},{"key":"pone.0309466.ref045","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1016\/S1473-3099(20)30631-9","article-title":"SeroTracker: a global SARS-CoV-2 seroprevalence dashboard","volume":"21","author":"RK Arora","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"pone.0309466.ref046","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00685-21","article-title":"High SARS-CoV-2 Seroprevalence in Rural Peru, 2021: a Cross-Sectional Population-Based Study.","volume":"6","author":"A Moreira-Soto","year":"2021","journal-title":"mSphere"},{"key":"pone.0309466.ref047","doi-asserted-by":"crossref","first-page":"101026","DOI":"10.1016\/j.nmni.2022.101026","article-title":"Seroprevalence of IgM and IgG anti-SARS-COV-2 and associated factors among agricultural workers in Colombia.","volume":"48","author":"MF Rodr\u00edguez","year":"2022","journal-title":"New Microbes New Infect."},{"key":"pone.0309466.ref048","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/occmed\/kqad003","article-title":"SARS-CoV-2 seroprevalence in workers from a Colombian University Hospital.","volume":"73","author":"K Moreno-Medina","year":"2023","journal-title":"Occup Med (Chic Ill)."},{"key":"pone.0309466.ref049","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.jiph.2022.08.017","article-title":"Seroprevalence of antibodies against to SARS-CoV 2 in umbilical cord blood in two hospital centers in C\u00f3rdoba and Sucre, Colombia.","volume":"15","author":"J Berrocal","year":"2022","journal-title":"J Infect Public Health."},{"key":"pone.0309466.ref050","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.3390\/vaccines9101120","article-title":"Direct and Indirect Proof of SARS-CoV-2 Infections in Indigenous Wiwa Communities in North-Eastern Colombia\u2014A Cross-Sectional Assessment Providing Preliminary Surveillance Data.","volume":"9","author":"G Concha","year":"2021","journal-title":"Vaccines (Basel)."},{"key":"pone.0309466.ref051","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.placenta.2021.10.001","article-title":"Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region","volume":"115","author":"H Zambrano","year":"2021","journal-title":"Placenta"},{"key":"pone.0309466.ref052","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1038\/s41467-020-17318-x","article-title":"Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital.","volume":"11","author":"AL Garcia-Basteiro","year":"2020","journal-title":"Nat Commun."},{"key":"pone.0309466.ref053","doi-asserted-by":"crossref","first-page":"104437","DOI":"10.1016\/j.jcv.2020.104437","article-title":"SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients","volume":"128","author":"J Korth","year":"2020","journal-title":"Journal of Clinical Virology"},{"key":"pone.0309466.ref054","doi-asserted-by":"crossref","first-page":"100770","DOI":"10.1016\/j.eclinm.2021.100770","article-title":"Seroprevalence of SARS-CoV-2 IgG antibodies among health care workers prior to vaccine administration in Europe, the USA and East Asia: A systematic review and meta-analysis.","volume":"33","author":"A Hossain","year":"2021","journal-title":"EClinicalMedicine"},{"key":"pone.0309466.ref055","first-page":"49","article-title":"DEL CANT\u00d3N AMBATO DENTRO DE LA EMERGENCIA SARS-COV2, UN AN\u00c1LISIS DE LA SEGU-RIDAD JUR\u00cdDICA.","author":"JP Santamar\u00eda Velaszo","year":"2021","journal-title":"Revista Metropolitana de Ciencias Aplicadas."},{"key":"pone.0309466.ref056","doi-asserted-by":"crossref","first-page":"0","DOI":"10.4193\/Rhin21.415","article-title":"A follow-up on quantitative and qualitative olfactory dysfunction and other symptoms in patients recovering from COVID-19 smell loss","volume":"0","author":"K Ohla","year":"2022","journal-title":"Rhinology journal"},{"key":"pone.0309466.ref057","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.wjorl.2021.02.001","article-title":"Objective screening for olfactory and gustatory dysfunction during the COVID\u201019 pandemic: A prospective study in healthcare workers using self\u2010administered testing.","volume":"8","author":"AC Cao","year":"2022","journal-title":"World J Otorhinolaryngol Head Neck Surg"},{"key":"pone.0309466.ref058","doi-asserted-by":"crossref","first-page":"38","DOI":"10.11606\/s1518-8787.2021055003673","article-title":"Doen\u00e7as cr\u00f4nicas n\u00e3o transmiss\u00edveis e covid-19: resultados do estudo Epicovid-19 Brasil.","volume":"55","author":"MA Mesenburg","year":"2021","journal-title":"Rev Saude Publica."},{"key":"pone.0309466.ref059","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1590\/1806-9282.20220078","article-title":"Self-reported symptoms and seroprevalence against SARS-CoV-2 in the population of Mato Grosso: a household-based survey in 2020.","volume":"68","author":"ACP Ter\u00e7as-Trettel","year":"2022","journal-title":"Rev Assoc Med Bras."},{"key":"pone.0309466.ref060","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1080\/02664763.2012.722608","article-title":"Inference for serological surveys investigating past exposures to infections resulting in long-lasting immunity\u2013an approach using finite mixture models with concomitant information.","volume":"39","author":"IC Ster","year":"2012","journal-title":"J Appl Stat"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0309466","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T18:18:14Z","timestamp":1724955494000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0309466"}},"subtitle":[],"editor":[{"given":"Mariana Louren\u00e7o","family":"Freire","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":60,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0309466","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2024,8,29]]}}}