{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T22:24:59Z","timestamp":1777328699836,"version":"3.51.4"},"reference-count":59,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016036","name":"Health~Holland","doi-asserted-by":"publisher","award":["LSH18079"],"award-info":[{"award-number":["LSH18079"]}],"id":[{"id":"10.13039\/100016036","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>If communicated adequately, numerical decision-relevant information can support informed and shared decision making. Visual formats are recommended, but which format supports patients depending on their health literacy (HL) levels for specific decisions is unclear.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Study aim<\/jats:title>\n<jats:p>The aim of this study is to investigate: 1) the effect of survival rates and side-effects presentation formats on comprehension and \u2018feeling informed\u2019; 2) differential effects among women with higher\/lower HL, with adjuvant systemic breast cancer therapy as case example.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Two online experiments among women from the Dutch population without a history of breast cancer were conducted. Experiment 1 had a 3 (survival rate format: text block\u2013bar graph\u2013icon array) x 2 (HL: low\u2013high) between-subjects design. Experiment 2 had a 5 (side-effects format: no probability information\u2013probability information in numbers with or without a visualisation\u2013probability information in numbers with or without a visualisation accompanied by a description of the side-effects) x 2 (HL: low\u2013high) design. Primary outcomes were comprehension and feeling informed (Experiment 2 only). Formats were previously designed in co-creation with patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>In Experiment 1, presentation format did not affect gist or verbatim comprehension. Higher HL was associated with higher gist comprehension. Experiment 2 showed an interaction between presentation format and HL on \u2018feeling informed\u2019. When provided with visualised probability information without a description of the side-effects, women with lower HL felt better informed than women with higher HL.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Visual formats did not enhance comprehension of survival rate information beyond a well-designed text block format. However, none of the formats could overcome HL differences. When designing decision-relevant information, visualisations might not necessarily provide an advantage over structured numerical information for both patients with lower and higher HL. However, a deeper understanding of presenting side-effect information is warranted.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0309668","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T17:22:55Z","timestamp":1725384175000},"page":"e0309668","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Presenting decision-relevant numerical information to Dutch women aged 50\u201370 with varying levels of health literacy: Case example of adjuvant systemic therapy for breast cancer"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0886-9224","authenticated-orcid":true,"given":"Inge S.","family":"van Strien-Knippenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3602-3875","authenticated-orcid":true,"given":"Dani\u00eblle R. 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