{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:32:37Z","timestamp":1793093557979,"version":"4.5.0"},"reference-count":108,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    It is thought to be risk-free, environmentally benign, and safe for biological processes to produce zinc oxide nanoparticles from renewable resources. This study examined\n                    <jats:italic>Cassia javanica\u2019s<\/jats:italic>\n                    ability to create ZnONPs. The generated ZnONPs were analyzed using a variety of techniques, such as TEM, FTIR spectroscopy, UV-Vis spectroscopy, and XRD analysis. The antibacterial potential of ZnONPs has been investigated using both Agar well diffusion and microtitreplate (MTP) methods. One method used to evaluate ZnONPs\u2019 capacity to scavenge free radicals at different concentrations was the DPPH method. The permanent zinc oxide (ZnO) shape and the naturally occurring crystal structure of ZnONPs were validated by the XRD data. ZnONPs showed antibacterial activity with MICs of 31.7 \u03bcg\/mL toward\n                    <jats:italic>Bacillus subtilis<\/jats:italic>\n                    , 62.5 \u03bcg\/mL for\n                    <jats:italic>Salmonella typhimurium<\/jats:italic>\n                    ,\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    while\n                    <jats:italic>Clostridium sporogenes<\/jats:italic>\n                    and\n                    <jats:italic>Bacillus pumilus<\/jats:italic>\n                    was 125\u03bcg\/mL. Furthermore, ZnONPs demonstrated a range of antibiofilm activities toward\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (MRSA). ZnONPs showed an intriguing antioxidant capacity, achieving IC\n                    <jats:sub>50<\/jats:sub>\n                    of 109.3 \u03bcg\/ml \u03bcg\/mL. Additionally, ZnONPs demonstrated low toxic effect on Vero cell with IC\n                    <jats:sub>50<\/jats:sub>\n                    154.01 \u03bcg\/mL as well as possible anticancer action when applied to the carcinoma cell lines HepG2 with IC\n                    <jats:sub>50<\/jats:sub>\n                    of 47.48 \u03bcg\/mL. Furthermore, ZnONPs at 62.5 \u03bcg\/mL had a promising antiviral impact against HSV1 and COX B4, with antiviral activities of 75.4% and 65.8%, respectively.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0310927","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T13:26:08Z","timestamp":1727789168000},"page":"e0310927","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["Investigating the in vitro antibacterial, antibiofilm, antioxidant, anticancer and antiviral activities of zinc oxide nanoparticles biofabricated from Cassia javanica"],"prefix":"10.1371","volume":"19","author":[{"given":"Mohammed S.","family":"Almuhayawi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed H.","family":"Alruhaili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed K. Y.","family":"Soliman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muyassar K.","family":"Tarabulsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruba A.","family":"Ashy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amna A.","family":"Saddiq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4025-8586","authenticated-orcid":true,"given":"Samy","family":"Selim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasir","family":"Alruwaili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salem S.","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,10,1]]},"reference":[{"key":"pone.0310927.ref001","article-title":"Silver Nanoparticles Derived from Probiotic Lactobacillus casei\u2014a Novel Approach for Combating Bacterial Infections and Cancer","author":"AJ Siddiqui","year":"2023","journal-title":"Probiotics and Antimicrobial Proteins"},{"issue":"7","key":"pone.0310927.ref002","doi-asserted-by":"crossref","first-page":"853","DOI":"10.3390\/antibiotics11070853","article-title":"Biosynthesized Silver Nanoparticles from Eruca sativa Miller Leaf Extract Exhibits Antibacterial, Antioxidant, Anti-Quorum-Sensing, Antibiofilm, and Anti-Metastatic Activities.","volume":"11","author":"AM Awadelkareem","year":"2022","journal-title":"Antibiotics."},{"issue":"1","key":"pone.0310927.ref003","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/molecules25010112","article-title":"The history of nanoscience and nanotechnology: from chemical\u2013physical applications to nanomedicine.","volume":"25","author":"S Bayda","year":"2019","journal-title":"Molecules."},{"issue":"8","key":"pone.0310927.ref004","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.3390\/molecules26082236","article-title":"Green synthesis and applications of ZnO and TiO2 nanostructures.","volume":"26","author":"RA Gon\u00e7alves","year":"2021","journal-title":"Molecules."},{"issue":"2","key":"pone.0310927.ref005","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1007\/s12010-022-04199-7","article-title":"Biosynthesis of silver and gold nanoparticles and their efficacy towards antibacterial, antibiofilm, cytotoxicity, and antioxidant activities","volume":"195","author":"MK Soliman","year":"2023","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"7","key":"pone.0310927.ref006","doi-asserted-by":"crossref","first-page":"4457","DOI":"10.1007\/s12010-023-04696-3","article-title":"Recent Insights into Nanotechnology in Colorectal Cancer","volume":"196","author":"AAZ Dezfuli","year":"2024","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"4","key":"pone.0310927.ref007","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1007\/s12668-022-01026-5","article-title":"Baker\u2019s Yeast-Mediated Silver Nanoparticles: Characterisation and Antimicrobial Biogenic Tool for Suppressing Pathogenic Microbes.","volume":"12","author":"SS Salem","year":"2022","journal-title":"BioNanoScience."},{"issue":"1","key":"pone.0310927.ref008","article-title":"Biosynthesis and characterization of selenium and silver nanoparticles using Trichoderma viride filtrate and their impact on Culex pipiens.","volume":"13","author":"HF Abd-Elkhalek","year":"2024","journal-title":"Green Processing and Synthesis."},{"key":"pone.0310927.ref009","doi-asserted-by":"crossref","first-page":"102369","DOI":"10.1016\/j.pmpp.2024.102369","article-title":"Promising antagonistic effect of bimetallic silver-selenium nanoparticles against Ralstonia solanacearum-causing wilt disease in eggplant (Solanum melongena L.).","volume":"133","author":"MS Attia","year":"2024","journal-title":"Physiological and Molecular Plant Pathology"},{"issue":"1","key":"pone.0310927.ref010","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12896-024-00852-7","article-title":"Hindering the biofilm of microbial pathogens and cancer cell lines development using silver nanoparticles synthesized by epidermal mucus proteins from Clarias gariepinus","volume":"24","author":"AN Alabssawy","year":"2024","journal-title":"BMC Biotechnology"},{"key":"pone.0310927.ref011","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.3389\/fmicb.2018.01218","article-title":"Mechanism of anti-bacterial activity of zinc oxide nanoparticle against carbapenem-resistant Acinetobacter baumannii","volume":"9","author":"V Tiwari","year":"2018","journal-title":"Frontiers in microbiology"},{"key":"pone.0310927.ref012","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1007\/s12011-020-02369-4","article-title":"Eco-friendly mycogenic synthesis of ZnO and CuO nanoparticles for in vitro antibacterial, antibiofilm, and antifungal applications","volume":"199","author":"AA Mohamed","year":"2021","journal-title":"Biological trace element research"},{"key":"pone.0310927.ref013","first-page":"1","article-title":"Multifunctional properties of silver and gold nanoparticles synthesis by Fusarium pseudonygamai.","author":"MK Soliman","year":"2022","journal-title":"Biomass Conversion and Biorefinery."},{"issue":"1","key":"pone.0310927.ref014","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s12010-023-04482-1","article-title":"Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Lawsonia inermis Against Common Pathogens from Urinary Tract Infection","volume":"196","author":"A Said","year":"2024","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"12","key":"pone.0310927.ref015","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.3390\/catal11121507","article-title":"Synthesis and characterization of zinc oxide nanoparticles using Acacia caesia bark extract and its photocatalytic and antimicrobial activities.","volume":"11","author":"J Ashwini","year":"2021","journal-title":"Catalysts."},{"key":"pone.0310927.ref016","first-page":"1","article-title":"Response surface methodology: Optimization of myco-synthesized gold and silver nanoparticles by Trichoderma saturnisporum.","author":"M Abu-Elghait","year":"2023","journal-title":"Biomass Conversion and Biorefinery."},{"issue":"5","key":"pone.0310927.ref017","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1007\/s12010-022-03809-8","article-title":"Bio-fabrication of Selenium Nanoparticles Using Baker\u2019s Yeast Extract and Its Antimicrobial Efficacy on Food Borne Pathogens","volume":"194","author":"SS Salem","year":"2022","journal-title":"Applied Biochemistry and Biotechnology"},{"issue":"1","key":"pone.0310927.ref018","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s13399-022-03412-1","article-title":"Phytofabrication of zinc oxide nanoparticles with advanced characterization and its antioxidant, anticancer, and antimicrobial activity against pathogenic microorganisms.","volume":"13","author":"TM Abdelghany","year":"2023","journal-title":"Biomass Conversion and Biorefinery"},{"issue":"6","key":"pone.0310927.ref019","doi-asserted-by":"crossref","first-page":"893","DOI":"10.3390\/life12060893","article-title":"Green biosynthesis of selenium nanoparticles using orange peel waste: Characterization, antibacterial and antibiofilm activities against multidrug-resistant bacteria.","volume":"12","author":"SS Salem","year":"2022","journal-title":"Life"},{"key":"pone.0310927.ref020","article-title":"Correction to: Green synthesized ZnO nanoparticles by Saccharomyces cerevisiae and their antibacterial activity and photocatalytic degradation.","author":"AM El-Khawaga","year":"2023","journal-title":"Biomass Conversion and Biorefinery."},{"issue":"1","key":"pone.0310927.ref021","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2217\/nnm.13.191","article-title":"Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles","volume":"9","author":"R Toy","year":"2014","journal-title":"Nanomedicine"},{"key":"pone.0310927.ref022","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.2147\/IJN.S46900","article-title":"Nanopharmaceuticals (part 1): products on the market.","author":"V Weissig","year":"2014","journal-title":"International journal of nanomedicine"},{"issue":"4","key":"pone.0310927.ref023","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1007\/s00203-023-03467-2","article-title":"A mini review on green nanotechnology and its development in biological effects","volume":"205","author":"SS Salem","year":"2023","journal-title":"Archives of Microbiology"},{"issue":"10","key":"pone.0310927.ref024","doi-asserted-by":"crossref","first-page":"4927","DOI":"10.1039\/C7NR08499D","article-title":"Unexpected insights into antibacterial activity of zinc oxide nanoparticles against methicillin resistant Staphylococcus aureus (MRSA).","volume":"10","author":"U Kadiyala","year":"2018","journal-title":"Nanoscale."},{"key":"pone.0310927.ref025","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.micpath.2018.03.048","article-title":"Evaluation of antibacterial and antioxidant potential of the zinc oxide nanoparticles synthesized by aqueous and polyol method","volume":"119","author":"S Soren","year":"2018","journal-title":"Microbial pathogenesis"},{"issue":"8","key":"pone.0310927.ref026","doi-asserted-by":"crossref","first-page":"103251","DOI":"10.1016\/j.arabjc.2021.103251","article-title":"Zinc oxide nanoparticles fabrication using Eriobotrya japonica leaves extract: Photocatalytic performance and antibacterial activity evaluation","volume":"14","author":"A Nazir","year":"2021","journal-title":"Arabian Journal of Chemistry"},{"issue":"1","key":"pone.0310927.ref027","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1574-6968.2007.01012.x","article-title":"Antibacterial activity of ZnO nanoparticle suspensions on a broad spectrum of microorganisms","volume":"279","author":"N Jones","year":"2008","journal-title":"FEMS microbiology letters"},{"key":"pone.0310927.ref028","first-page":"2021","article-title":"Plant-based synthesis of zinc oxide nanoparticles (ZnO-NPs) using aqueous leaf extract of aquilegia pubiflora: Their antiproliferative activity against HepG2 cells inducing reactive oxygen species and other in vitro properties.","author":"H Jan","year":"2021","journal-title":"Oxidative medicine and cellular longevity."},{"issue":"3","key":"pone.0310927.ref029","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1756-1051.1993.tb00048.x","article-title":"Boesenbergia tenuispicata (Zingiberaceae): a new species from Thailand","volume":"13","author":"K. Larsen","year":"1993","journal-title":"Nordic journal of botany"},{"issue":"1","key":"pone.0310927.ref030","first-page":"47","article-title":"Hypoglycemic activity of Cassia javanica Linn.","volume":"3","author":"UC Kumavat","year":"2012","journal-title":"in normal and streptozotocin-induced diabetic rats. Journal of advanced pharmaceutical technology & research"},{"issue":"4","key":"pone.0310927.ref031","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1007\/s10876-016-1016-9","article-title":"Biosynthesis, Characterization and Antibacterial Effect of Phenolics-Coated Silver Nanoparticles Using Cassia javanica L","volume":"27","author":"SC Bankalgi","year":"2016","journal-title":"Journal of Cluster Science"},{"issue":"2","key":"pone.0310927.ref032","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1099\/jmm.0.46110-0","article-title":"ent-Epiafzelechin-(4 \u03b1\u2192 8)-epiafzelechin extracted from Cassia javanica inhibits herpes simplex virus type 2 replication.","volume":"55","author":"H-Y Cheng","year":"2006","journal-title":"Journal of Medical Microbiology"},{"key":"pone.0310927.ref033","first-page":"2","article-title":"Phytochemical screening of certain plant species of Agra city","author":"JI Pandith","year":"2012","journal-title":"Journal of drug delivery and therapeutics"},{"key":"pone.0310927.ref034","first-page":"47","article-title":"An overall view of cassia species phytochemical constituents and its pharmacological uses","volume":"3","author":"B Lavanya","year":"2018","journal-title":"Int J Pharm Sci Res"},{"key":"pone.0310927.ref035","doi-asserted-by":"crossref","first-page":"100325","DOI":"10.1016\/j.prmcm.2023.100325","article-title":"Cassia species: A review of traditional uses, phytochemistry and pharmacology","author":"E Zibaee","year":"2023","journal-title":"Pharmacological Research-Modern Chinese Medicine"},{"issue":"1","key":"pone.0310927.ref036","doi-asserted-by":"crossref","first-page":"9055","DOI":"10.1038\/s41598-020-65949-3","article-title":"Green route to synthesize Zinc Oxide Nanoparticles using leaf extracts of Cassia fistula and Melia azadarach and their antibacterial potential.","volume":"10","author":"M Naseer","year":"2020","journal-title":"Scientific Reports"},{"key":"pone.0310927.ref037","first-page":"113","article-title":"Antibiotic assay by agar-well diffusion method","volume":"15","author":"C. Perez","year":"1990","journal-title":"Acta Biol Med Exp"},{"issue":"4","key":"pone.0310927.ref038","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01934-17","article-title":"CLSI methods development and standardization working group best practices for evaluation of antimicrobial susceptibility tests","volume":"56","author":"RM Humphries","year":"2018","journal-title":"Journal of clinical microbiology"},{"issue":"23","key":"pone.0310927.ref039","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.clinmicnews.2019.11.002","article-title":"What\u2019s new from the CLSI subcommittee on antimicrobial susceptibility testing M100","volume":"41","author":"TC Abbey","year":"2019","journal-title":"Clinical Microbiology Newsletter"},{"issue":"21","key":"pone.0310927.ref040","doi-asserted-by":"crossref","first-page":"3830","DOI":"10.1080\/14786419.2020.1741583","article-title":"Meleagrin from marine fungus Emericella dentata Nq45: crystal structure and diverse biological activity studies","volume":"35","author":"A Hamed","year":"2021","journal-title":"Natural Product Research"},{"issue":"1-2","key":"pone.0310927.ref041","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/0022-1759(94)90034-5","article-title":"A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia","volume":"174","author":"A Van de Loosdrecht","year":"1994","journal-title":"Journal of immunological methods"},{"issue":"7","key":"pone.0310927.ref042","first-page":"93","article-title":"Activity of Turbinaria ornata (turner) J. Agade against blue tongue virus (Btv).","volume":"6","author":"P. Sethi","year":"2016","journal-title":"IOSR J Pharm."},{"key":"pone.0310927.ref043","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1590\/S0074-02762003000600023","article-title":"Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum.","volume":"98","author":"C Andrighetti-Fr\u00f6hner","year":"2003","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz"},{"key":"pone.0310927.ref044","article-title":"editors. Eco-friendly synthesis, characterization, and antimicrobial studies of Zinc oxide nanoparticles using Cassia Javanica Leaf extract.","author":"TF Owoeye","year":"2024","journal-title":"2024 International Conference on Science, Engineering and Business for Driving Sustainable Development Goals (SEB4SDG);"},{"issue":"10","key":"pone.0310927.ref045","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1039\/c1gc15386b","article-title":"Green synthesis of metal nanoparticles using plants","volume":"13","author":"S. Iravani","year":"2011","journal-title":"Green chemistry"},{"key":"pone.0310927.ref046","doi-asserted-by":"crossref","first-page":"6799","DOI":"10.1007\/s00253-018-9146-7","article-title":"Role of plant phytochemicals and microbial enzymes in biosynthesis of metallic nanoparticles","volume":"102","author":"M Ovais","year":"2018","journal-title":"Applied microbiology and biotechnology"},{"issue":"4","key":"pone.0310927.ref047","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/jfb14040205","article-title":"Green synthesis of zinc oxide nanoparticles using an aqueous extract of punica granatum for antimicrobial and catalytic activity","volume":"14","author":"A Fouda","year":"2023","journal-title":"Journal of Functional Biomaterials"},{"issue":"11","key":"pone.0310927.ref048","doi-asserted-by":"crossref","first-page":"10133","DOI":"10.1007\/s13399-021-01873-4","article-title":"Green biosynthesis of zinc and selenium oxide nanoparticles using callus extract of Ziziphus spina-christi: Characterization, antimicrobial, and antioxidant activity.","volume":"13","author":"I Lashin","year":"2023","journal-title":"Biomass Conversion and Biorefinery"},{"key":"pone.0310927.ref049","doi-asserted-by":"crossref","first-page":"100011","DOI":"10.1016\/j.plana.2022.100011","article-title":"Green synthesis of zinc oxide nanoparticles using Vernonia cinerea leaf extract and evaluation as nano-nutrient on the growth and development of tomato seedling","volume":"2","author":"Z Azim","year":"2022","journal-title":"Plant Nano Biology"},{"key":"pone.0310927.ref050","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.sajb.2022.03.016","article-title":"Synthesis of zinc oxide nanoparticles mediated by Dictyota dichotoma endophytic fungi and its photocatalytic degradation of fast green dye and antibacterial applications","volume":"151","author":"RV Kumar","year":"2022","journal-title":"South African Journal of Botany"},{"issue":"4","key":"pone.0310927.ref051","doi-asserted-by":"crossref","first-page":"2270","DOI":"10.1016\/j.sjbs.2021.11.065","article-title":"Green synthesis of zinc oxide nanoparticles using Anoectochilus elatus, and their biomedical applications","volume":"29","author":"N Vijayakumar","year":"2022","journal-title":"Saudi Journal of Biological Sciences"},{"issue":"22","key":"pone.0310927.ref052","doi-asserted-by":"crossref","first-page":"6983","DOI":"10.3390\/ma14226983","article-title":"Green synthesis of Zinc Oxide Nanoparticles (ZnO-NPs) by Pseudomonas aeruginosa and their activity against pathogenic microbes and common house mosquito, Culex pipiens.","volume":"14","author":"AM Abdo","year":"2021","journal-title":"Materials."},{"issue":"9","key":"pone.0310927.ref053","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.3390\/ph15091057","article-title":"Zinc oxide nanoparticles as potential delivery carrier: Green synthesis by Aspergillus niger endophytic fungus, characterization, and in vitro\/in vivo antibacterial activity","volume":"15","author":"DH Abdelkader","year":"2022","journal-title":"Pharmaceuticals"},{"key":"pone.0310927.ref054","doi-asserted-by":"crossref","first-page":"748739","DOI":"10.3389\/fcimb.2021.748739","article-title":"Effects of zinc oxide nanoparticles synthesized using aspergillus niger on carbapenem-resistant klebsiella pneumonia in vitro and in vivo","volume":"11","author":"E Rasha","year":"2021","journal-title":"Frontiers in Cellular and Infection Microbiology"},{"key":"pone.0310927.ref055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/6629180","article-title":"Plant-mediated biosynthesis and photocatalysis activities of zinc oxide nanoparticles: a prospect towards dyes mineralization","volume":"2021","author":"MA Fagier","year":"2021","journal-title":"Journal of Nanotechnology"},{"issue":"5","key":"pone.0310927.ref056","doi-asserted-by":"crossref","first-page":"102047","DOI":"10.1016\/j.jksus.2022.102047","article-title":"Facile green synthesis of semiconductive ZnO nanoparticles for photocatalytic degradation of dyes from the textile industry: A kinetic approach","volume":"34","author":"JP Shubha","year":"2022","journal-title":"Journal of king saud university-science"},{"key":"pone.0310927.ref057","doi-asserted-by":"crossref","first-page":"103444","DOI":"10.1016\/j.jddst.2022.103444","article-title":"Biogenic synthesis of zinc oxide nanoparticles using mushroom fungus Cordyceps militaris: Characterization and mechanistic insights of therapeutic investigation","volume":"73","author":"C Dias","year":"2022","journal-title":"Journal of Drug Delivery Science and Technology"},{"issue":"7","key":"pone.0310927.ref058","doi-asserted-by":"crossref","first-page":"756","DOI":"10.3390\/catal12070756","article-title":"Phyco-synthesized zinc oxide nanoparticles using marine macroalgae, Ulva fasciata Delile, characterization, antibacterial activity, photocatalysis, and tanning wastewater treatment.","volume":"12","author":"A Fouda","year":"2022","journal-title":"Catalysts."},{"key":"pone.0310927.ref059","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12951-020-00704-4","article-title":"Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects","volume":"18","author":"R Javed","year":"2020","journal-title":"Journal of Nanobiotechnology"},{"key":"pone.0310927.ref060","doi-asserted-by":"crossref","first-page":"170352","DOI":"10.1016\/j.ijleo.2022.170352","article-title":"Efficient photocatalytic degradation of industrial wastewater dye by Grewia asiatica mediated zinc oxide nanoparticles.","volume":"272","author":"A Aziz","year":"2023","journal-title":"Optik"},{"key":"pone.0310927.ref061","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.micpath.2018.09.030","article-title":"In-Vitro cytotoxicity, antibacterial, and UV protection properties of the biosynthesized Zinc oxide nanoparticles for medical textile applications","volume":"125","author":"A Fouda","year":"2018","journal-title":"Microbial pathogenesis"},{"issue":"4","key":"pone.0310927.ref062","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/slct.202003517","article-title":"Seaweed mediated fabrication of zinc oxide nanoparticles and their antibacterial, antifungal and anticancer applications.","volume":"6","author":"K Anjali","year":"2021","journal-title":"ChemistrySelect."},{"issue":"1","key":"pone.0310927.ref063","article-title":"mangostana L.) leaf extract: Comparative preliminary in vitro antibacterial study.","volume":"13","author":"YB Chan","year":"2024","journal-title":"Green synthesis of ZnO nanoparticles using the mangosteenGreen Processing and Synthesis."},{"key":"pone.0310927.ref064","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1016\/j.jmrt.2022.08.028","article-title":"Synthesis, characterization, and preliminary in vitro antibacterial evaluation of ZnO nanoparticles derived from soursop (Annona muricata L.) leaf extract as a green reducing agent","volume":"20","author":"V Selvanathan","year":"2022","journal-title":"Journal of Materials Research and Technology"},{"key":"pone.0310927.ref065","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.molstruc.2019.04.026","article-title":"Cytotoxicity and antibacterial activities of plant-mediated synthesized zinc oxide (ZnO) nanoparticles using Punica granatum (pomegranate) fruit peels extract.","volume":"1189","author":"SNAM Sukri","year":"2019","journal-title":"Journal of Molecular 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cytofriendly properties","volume":"115","author":"M Saravanan","year":"2018","journal-title":"Microbial pathogenesis"},{"key":"pone.0310927.ref069","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jtemb.2017.10.002","article-title":"Bacterial exopolysaccharide (EPS)-coated ZnO nanoparticles showed high antibiofilm activity and larvicidal toxicity against malaria and Zika virus vectors.","volume":"45","author":"M Abinaya","year":"2018","journal-title":"Journal of Trace Elements in Medicine and Biology"},{"key":"pone.0310927.ref070","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.mssp.2014.12.023","article-title":"Green synthesis of multifunctional zinc oxide (ZnO) nanoparticles using Cassia fistula plant extract and their photodegradative, antioxidant and antibacterial activities.","volume":"31","author":"D Suresh","year":"2015","journal-title":"Materials Science in Semiconductor Processing"},{"key":"pone.0310927.ref071","first-page":"40","article-title":"Molecular taxonomic identification, biosynthesis and in vitro antibacterial activity of ZNO nanoparticles using Boerhavia diffusa against MRSA","volume":"8","author":"B Joseph","year":"2016","journal-title":"Int J Toxicol Pharmacol Res"},{"key":"pone.0310927.ref072","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1007\/s11164-016-2830-2","article-title":"Evaluation of photocatalytic activity, antibacterial and cytotoxic effects of green synthesized ZnO nanoparticles by Sechium edule leaf extract","volume":"43","author":"N Elavarasan","year":"2017","journal-title":"Research on Chemical Intermediates"},{"key":"pone.0310927.ref073","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.saa.2015.07.067","article-title":"Facile green fabrication of nanostructure ZnO plates, bullets, flower, prismatic tip, closed pine cone: their antibacterial, antioxidant, photoluminescent and photocatalytic properties.","volume":"152","author":"H Madan","year":"2016","journal-title":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy."},{"key":"pone.0310927.ref074","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s40097-018-0271-8","article-title":"Biosynthesis, characterization, and antibacterial activity of zinc oxide nanoparticles derived from Bauhinia tomentosa leaf extract","volume":"8","author":"G Sharmila","year":"2018","journal-title":"Journal of Nanostructure in Chemistry"},{"issue":"10","key":"pone.0310927.ref075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3390\/genes8100281","article-title":"Eco-friendly formulated zinc oxide nanoparticles: induction of cell cycle arrest and apoptosis in the MCF-7 cancer cell line.","volume":"8","author":"A Boroumand Moghaddam","year":"2017","journal-title":"Genes"},{"key":"pone.0310927.ref076","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s10876-019-01551-6","article-title":"Biofabrication of zinc oxide nanoparticles from Aspergillus niger, their antioxidant, antimicrobial and anticancer activity","volume":"30","author":"Y Gao","year":"2019","journal-title":"Journal of Cluster Science"},{"key":"pone.0310927.ref077","first-page":"1","article-title":"Anticancer activity of fungal L-asparaginase conjugated with zinc oxide nanoparticles","volume":"26","author":"G Baskar","year":"2015","journal-title":"Journal of Materials Science: Materials in Medicine"},{"issue":"7","key":"pone.0310927.ref078","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1049\/iet-nbt.2018.5060","article-title":"Biosynthesis of zinc oxide nanoparticles using anjbar (root of Persicaria bistorta) extract and their cytotoxic effects on human breast cancer cell line (MCF\u20107).","volume":"13","author":"E Safavi","year":"2019","journal-title":"IET nanobiotechnology"},{"issue":"1","key":"pone.0310927.ref079","first-page":"015008","article-title":"Green synthesis and characterization of zinc oxide nanoparticle using insulin plant (Costus pictus D. Don) and investigation of its antimicrobial as well as anticancer activities","volume":"9","author":"J Suresh","year":"2018","journal-title":"Advances in Natural Sciences: Nanoscience and Nanotechnology."},{"key":"pone.0310927.ref080","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.enzmictec.2018.06.009","article-title":"Biosynthesis of zinc oxide nanoparticles usingMangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells.","volume":"117","author":"S Rajeshkumar","year":"2018","journal-title":"Enzyme and microbial technology"},{"issue":"4","key":"pone.0310927.ref081","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.sjbs.2015.05.016","article-title":"Biosynthesis and antibacterial activity of ZnO nanoparticles using Trifolium pratense flower extract","volume":"23","author":"R Dobrucka","year":"2016","journal-title":"Saudi journal of biological sciences"},{"key":"pone.0310927.ref082","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jphotobiol.2018.04.050","article-title":"Bioluminescent and structural features of native folded Gaussia luciferase.","volume":"183","author":"MD Larionova","year":"2018","journal-title":"Journal of Photochemistry and Photobiology B: Biology."},{"key":"pone.0310927.ref083","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s40097-016-0205-2","article-title":"Antibiofilm activity of biogenic copper and zinc oxide nanoparticles-antimicrobials collegiate against multiple drug resistant bacteria: a nanoscale approach","volume":"6","author":"C Ashajyothi","year":"2016","journal-title":"Journal of Nanostructure in Chemistry"},{"issue":"2","key":"pone.0310927.ref084","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1021\/es504259s","article-title":"Toxicity of metal oxide nanoparticles in Escherichia coli correlates with conduction band and hydration energies","volume":"49","author":"C Kaweeteerawat","year":"2015","journal-title":"Environmental science & technology"},{"key":"pone.0310927.ref085","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10876-019-01651-3","article-title":"Response surface methodology optimization of mono-dispersed MgO nanoparticles fabricated by ultrasonic-assisted sol\u2013gel method for outstanding antimicrobial and antibiofilm activities","volume":"31","author":"CW Wong","year":"2020","journal-title":"Journal of Cluster Science"},{"key":"pone.0310927.ref086","doi-asserted-by":"crossref","first-page":"127069","DOI":"10.1016\/j.jtemb.2022.127069","article-title":"Investigation of morphological and biochemical changes of zinc oxide nanoparticles induced toxicity against multi drug resistance bacteria","volume":"74","author":"N Asif","year":"2022","journal-title":"Journal of Trace Elements in Medicine and Biology"},{"key":"pone.0310927.ref087","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ijbiomac.2019.12.030","article-title":"Biopolymer K-carrageenan wrapped ZnO nanoparticles as drug delivery vehicles for anti MRSA therapy","volume":"144","author":"S Vijayakumar","year":"2020","journal-title":"International journal of biological macromolecules"},{"key":"pone.0310927.ref088","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.msec.2019.04.035","article-title":"Phyto-mediated synthesis of zinc oxide nanoparticles of Berberis aristata: Characterization, antioxidant activity and antibacterial activity with special reference to urinary tract pathogens","volume":"102","author":"H Chandra","year":"2019","journal-title":"Materials Science and Engineering: C"},{"key":"pone.0310927.ref089","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10876-016-1087-7","article-title":"Biosynthesis, electrochemical, antimicrobial and antioxidant studies of silver nanoparticles mediated by Talinum triangulare aqueous leaf extract","volume":"28","author":"EE Elemike","year":"2017","journal-title":"Journal of Cluster Science"},{"key":"pone.0310927.ref090","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/s12668-017-0418-y","article-title":"Biosynthesis of zinc oxide nanoparticles using plant extracts of Aloe vera and Hibiscus sabdariffa: phytochemical, antibacterial, antioxidant and anti-proliferative studies.","volume":"7","author":"D Mahendiran","year":"2017","journal-title":"BioNanoScience."},{"key":"pone.0310927.ref091","first-page":"3481","article-title":"Synthesis and spectroscopic characterization of a zinc oxide-polyphenol nanohybrid from natural resources for enhanced antioxidant activity with less cytotoxicity.","volume":"43","author":"P Biswas","year":"2021","journal-title":"Materials Today: Proceedings."},{"key":"pone.0310927.ref092","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s12011-020-02138-3","article-title":"Green synthesis of metallic nanoparticles and their prospective biotechnological applications: an overview","volume":"199","author":"SS Salem","year":"2021","journal-title":"Biological trace element research"},{"issue":"8","key":"pone.0310927.ref093","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.3109\/17435390.2012.741724","article-title":"Comparative study of ZnO and TiO2 nanoparticles: physicochemical characterisation and toxicological effects on human colon carcinoma cells.","volume":"7","author":"I De Angelis","year":"2013","journal-title":"Nanotoxicology."},{"key":"pone.0310927.ref094","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.apsusc.2016.06.042","article-title":"Effect of capping agents: structural, optical and biological properties of ZnO nanoparticles","volume":"386","author":"R Javed","year":"2016","journal-title":"Applied Surface Science"},{"key":"pone.0310927.ref095","first-page":"74","article-title":"Drug screening for kinetoplastids diseases.","author":"J-R Ioset","year":"2009","journal-title":"A training manual for screening in neglected diseases."},{"key":"pone.0310927.ref096","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.toxrep.2017.07.005","article-title":"In vitro cytotoxicity of zinc oxide, iron oxide and copper nanopowders prepared by green synthesis","volume":"4","author":"S Saranya","year":"2017","journal-title":"Toxicology Reports"},{"issue":"4","key":"pone.0310927.ref097","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3109\/15376516.2015.1045654","article-title":"Zinc oxide nanoparticles induced cyto-and genotoxicity in kidney epithelial cells","volume":"25","author":"NK Uzar","year":"2015","journal-title":"Toxicology mechanisms and methods"},{"key":"pone.0310927.ref098","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1556-276X-7-602","article-title":"Cytotoxicity, oxidative stress, and genotoxicity in human hepatocyte and embryonic kidney cells exposed to ZnO nanoparticles.","volume":"7","author":"R Guan","year":"2012","journal-title":"Nanoscale research letters."},{"key":"pone.0310927.ref099","first-page":"347","article-title":"ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax\/bcl-2 pathways: role of oxidative stress.","author":"M Ahamed","year":"2017","journal-title":"Nanomedicine in Cancer: Jenny Stanford Publishing;"},{"key":"pone.0310927.ref100","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5772\/63437","article-title":"ZnO nanoparticles: a promising anticancer agent.","volume":"3","author":"G Bisht","year":"2016","journal-title":"Nanobiomedicine."},{"key":"pone.0310927.ref101","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cis.2017.07.033","article-title":"Zinc oxide nanoparticles: Synthesis, antiseptic activity and toxicity mechanism","volume":"249","author":"A Kr\u00f3l","year":"2017","journal-title":"Advances in colloid and interface science"},{"issue":"7","key":"pone.0310927.ref102","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1007\/s10904-023-02614-y","article-title":"The promising antibacterial and anticancer activity of green synthesized zinc nanoparticles in combination with silver and gold nanoparticles","volume":"33","author":"AS Abdelsattar","year":"2023","journal-title":"Journal of Inorganic and Organometallic Polymers and Materials"},{"key":"pone.0310927.ref103","doi-asserted-by":"crossref","first-page":"104171","DOI":"10.1016\/j.jff.2020.104171","article-title":"An overview of Neem (Azadirachta indica) and its potential impact on health.","volume":"74","author":"JF Islas","year":"2020","journal-title":"Journal of Functional Foods"},{"issue":"9","key":"pone.0310927.ref104","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.3390\/nano10091645","article-title":"Antiviral potential of nanoparticles\u2014Can nanoparticles fight against coronaviruses?","volume":"10","author":"S Gurunathan","year":"2020","journal-title":"Nanomaterials."},{"key":"pone.0310927.ref105","doi-asserted-by":"crossref","first-page":"8221","DOI":"10.2147\/IJN.S339404","article-title":"Antiviral activity of zinc oxide nanoparticles mediated by Plumbago indica L. extract against Herpes Simplex Virus Type 1 (HSV-1).","author":"MM Melk","year":"2021","journal-title":"International Journal of Nanomedicine"},{"issue":"4","key":"pone.0310927.ref106","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3390\/coatings11040388","article-title":"Utilizing of (zinc oxide nano-spray) for disinfection against \u201cSARS-CoV-2\u201d and 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