{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:33:23Z","timestamp":1774038803160,"version":"3.50.1"},"reference-count":59,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Clinical Helicobacter pylori adhesion subtype analysis and vaccine design and screening","award":["WKJ-ZJ-2018"],"award-info":[{"award-number":["WKJ-ZJ-2018"]}]},{"name":"Zhejiang Provincial Science and Technology Program of Traditional Chinese Medicine","award":["2023ZL266"],"award-info":[{"award-number":["2023ZL266"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Endoscopic antireflux therapy is widely used in clinical practice. Peroral endoscopic cardial constriction (PECC), antireflux mucosal intervention (ARMI), and radiofrequency ablation (RF) possess analogous antireflux mechanisms. This comprehensive systematic review and meta-analysis aimed to evaluate and compare the safety and effectiveness of antireflux therapy during endoscopic cardia peripheral tissue scar formation (ECSF) procedures. We comprehensively searched the Web of Science, PubMed, Embase, China National Knowledge Infrastructure, and Wan-Fang databases for articles published from January 1990 to January 2024. Network meta-analysis (NMA) was used to assess the outcomes, with outcome metrics including the Gastroesophageal Reflux Questionnaire (GERD-Q) score, proton pump inhibitor discontinuation rate, pH &lt;4.2 percent acid reflux time (AET), lower esophageal pressure (LES pressure), DeMeester score, adverse events, and patient satisfaction. Twenty studies involving 1219 patients were included. PECC was significantly superior to RF in lowering the patients\u2019 postoperative GERD-Q scores(MD = -2.34, 95% confidence interval (CI): [-3.02, -1.66]), augmentation of LES pressures(MD = 3.22, 95% CI: [1.21, 5.23]), and having a lower incidence of serious adverse events. ARMI was preferable to PECC (MD = -2.87, 95% CI [-4.23, -1.51])and RF (MD = -1.12, 95% CI [-1.79, -0.54]) in reducing the AET percentage, but was not as effective as PECC in lowering GERD-Q scores(MD = -1.50, 95% CI [-2.47, -0.53]). The incidence of adverse effects was less than 10% for all interventions, with most of them mildly self-resolving. Each ECSF procedure resulted in a favorable outcome in patients with GERD. Considering the safety and efficacy of treatment, PECC was the most favorable choice among ECSF procedures.<\/jats:p>","DOI":"10.1371\/journal.pone.0311208","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T19:03:06Z","timestamp":1735671786000},"page":"e0311208","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Network meta-analysis of the efficacy of endoscopic cardia peripheral tissue scar formation (ECSF) in the treatment of gastroesophageal reflux disease"],"prefix":"10.1371","volume":"19","author":[{"given":"Chaoyi","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunhai","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuanran","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diyun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianyue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GeSang","family":"ZhuoMa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingzhi","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-1723","authenticated-orcid":true,"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"issue":"3","key":"pone.0311208.ref001","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/gutjnl-2016-313589","article-title":"Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis","volume":"67","author":"LH Eusebi","year":"2018","journal-title":"Gut"},{"issue":"6","key":"pone.0311208.ref002","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/gutjnl-2012-304269","article-title":"Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review","volume":"63","author":"HB El-Serag","year":"2014","journal-title":"Gut"},{"issue":"9","key":"pone.0311208.ref003","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1136\/gutjnl-2016-311715","article-title":"Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett\u2019s oesophagus","volume":"65","author":"KM Fock","year":"2016","journal-title":"Gut"},{"issue":"15","key":"pone.0311208.ref004","doi-asserted-by":"crossref","first-page":"4154","DOI":"10.7150\/ijbs.65066","article-title":"Current Advancement on the Dynamic Mechanism of Gastroesophageal Reflux Disease","volume":"17","author":"Z Zheng","year":"2021","journal-title":"Int J Biol Sci"},{"issue":"6","key":"pone.0311208.ref005","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S2468-1253(20)30002-9","article-title":"The global burden of gastro-oesophageal reflux disease: more than just heartburn and regurgitation","volume":"5","author":"R Sweis","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"1","key":"pone.0311208.ref006","doi-asserted-by":"crossref","first-page":"13970","DOI":"10.1038\/s41598-023-41332-w","article-title":"Quality of life and severity of symptoms among patients with various degrees of reflux esophagitis: a prospective study.","volume":"13","author":"A Mari","year":"2023","journal-title":"Sci Rep."},{"issue":"4","key":"pone.0311208.ref007","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00535-022-01861-z","article-title":"Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021.","volume":"57","author":"K Iwakiri","year":"2022","journal-title":"J Gastroenterol"},{"issue":"6","key":"pone.0311208.ref008","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1053\/gast.1997.v112.pm9178669","article-title":"Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis","volume":"112","author":"N Chiba","year":"1997","journal-title":"Gastroenterology"},{"issue":"1","key":"pone.0311208.ref009","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1186\/s12876-023-03087-6","article-title":"Efficacy and safety of HIP1601 (dual delayed-release esomeprazole) 40 mg in erosive esophagitis compared to HGP1705 (delayed-release esomeprazole) 40 mg: a multicenter, randomized, double-blind, non-inferiority study.","volume":"23","author":"H Lim","year":"2023","journal-title":"BMC Gastroenterol.Dec 18"},{"issue":"Suppl 2","key":"pone.0311208.ref010","first-page":"S33","article-title":"Proton pump inhibitor failure\u2014what are the therapeutic options?","volume":"104","author":"R. Fass","year":"2009","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"pone.0311208.ref011","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00464-022-09817-3","article-title":"Multi-society consensus conference and guideline on the treatment of gastroesophageal reflux disease (GERD).","volume":"37","author":"BJ Slater","year":"2023","journal-title":"Surg Endosc."},{"issue":"4","key":"pone.0311208.ref012","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.cgh.2013.06.012","article-title":"Do endoscopic antireflux procedures fit in the current treatment paradigm of gastroesophageal reflux disease?","volume":"12","author":"JE Pandolfino","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"7","key":"pone.0311208.ref013","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1007\/s00464-021-08397-y","article-title":"Endoscopic cardial constriction with band ligation in the treatment of refractory gastroesophageal reflux disease: a preliminary feasibility study.","volume":"35","author":"ZT Li","year":"2021","journal-title":"Surg Endosc."},{"key":"pone.0311208.ref014","doi-asserted-by":"crossref","first-page":"17562848221094959","DOI":"10.1177\/17562848221094959","article-title":"Antireflux mucosal intervention (ARMI) procedures for refractory gastroesophageal reflux disease: a systematic review and meta-analysis.","volume":"15","author":"JH Yeh","year":"2022","journal-title":"Therap Adv Gastroenterol"},{"issue":"10","key":"pone.0311208.ref015","doi-asserted-by":"crossref","first-page":"e37062","DOI":"10.1097\/MD.0000000000037062","article-title":"Efficacy and safety of endoscopic cardia peripheral tissue scar formation (ECSF) for the treatment of refractory gastroesophageal reflux disease: A systematic review with meta-analysis.","volume":"103","author":"C Shi","year":"2024","journal-title":"Medicine (Baltimore)."},{"issue":"6","key":"pone.0311208.ref016","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1177\/0962280216669183","article-title":"Optimally estimating the sample mean from the sample size, median, mid-range, and\/or mid-quartile range.","volume":"27","author":"D Luo","year":"2018","journal-title":"Stat Methods Med Res."},{"issue":"5","key":"pone.0311208.ref017","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jrsm.1429","article-title":"Optimally estimating the sample standard deviation from the five-number summary.","volume":"11","author":"J Shi","year":"2020","journal-title":"Res Synth Methods."},{"key":"pone.0311208.ref018","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"JPT Higgins","year":"2011","journal-title":"BMJ"},{"issue":"02 vo 13","key":"pone.0311208.ref019","first-page":"79","article-title":"Effect of endoscopic cardiac constriction combined with esomeprazole in patients with reflux esophagitis complicated with hiatal hernia","author":"H Shi","year":"2021","journal-title":"Chinese Journal of Frontier Medicine"},{"issue":"08 vo 44","key":"pone.0311208.ref020","first-page":"810","article-title":"Clinical efficacy of peroral endoscopic cardial constriction for treatment of refractory gastroesophageal reflux disease","author":"J Liu","year":"2022","journal-title":"Guangxi Medical Journal"},{"issue":"18 vo 7","key":"pone.0311208.ref021","first-page":"54","article-title":"Clinical effect of transoral endoscopic cardiac constriction in the treatment of refractory gastroesophageal reflux disease","author":"H Li","year":"2022","journal-title":"Clinical Medical Research And Practice"},{"issue":"22 vo 17","key":"pone.0311208.ref022","first-page":"33","article-title":"Study the Clinical Value of Gastric Cardia Mucosal Constriction under Endoscope in the Treatment of Reflux Esophagitis.","author":"S Tang","year":"2020","journal-title":"Medical Innovation of China."},{"issue":"3","key":"pone.0311208.ref023","doi-asserted-by":"crossref","first-page":"306","DOI":"10.5056\/jnm21240","article-title":"Randomized Controlled Trial of Anti-reflux Mucosectomy Versus Radiofrequency Energy Delivery for Proton Pump Inhibitor-refractory Gastroesophageal Reflux Disease.","volume":"29","author":"Y Wang","year":"2023","journal-title":"J Neurogastroenterol Motil."},{"issue":"09 vo 19","key":"pone.0311208.ref024","first-page":"1697","article-title":"Efficacy ofa New Domestic Radiofrequency Ablation Instrument for Gastroesophageal Reflux Disease","author":"X Lu","year":"2019","journal-title":"Progress in Modern Biomedicine"},{"issue":"4","key":"pone.0311208.ref025","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/00365521.2018.1445775","article-title":"Endoscopic management of refractory gastroesophageal reflux disease","volume":"53","author":"WM Seleem","year":"2018","journal-title":"Scand J Gastroenterol"},{"issue":"4","key":"pone.0311208.ref026","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1007\/s00464-009-0671-4","article-title":"A prospective randomized trial of sham, single-dose Stretta, and double-dose Stretta for the treatment of gastroesophageal reflux disease.","volume":"24","author":"AMA Aziz","year":"2010","journal-title":"Surg Endosc."},{"issue":"5","key":"pone.0311208.ref027","article-title":"Treatment of gastroesophageal reflux disease using radiofrequency ablation (Stretta procedure): An interim analysis of a randomized trial.","volume":"36","author":"K R","year":"2017","journal-title":"Indian journal of gastroenterology: official journal of the Indian Society of Gastroenterology [Internet]."},{"issue":"31","key":"pone.0311208.ref028","first-page":"48","article-title":"Clinical study of endoscopic gastroesophageal valve ligation for refractory reflux esophagitis.","volume":"29","author":"J Yi","year":"2022","journal-title":"China Modern Medicine"},{"issue":"04","key":"pone.0311208.ref029","first-page":"5","article-title":"Long-term effect of sophageal gastric fundus ligation combined with someprazole magnesium enteric coated tablets on gastroesophageal reflux disease","volume":"42","author":"Y. Wang","year":"2022","journal-title":"Clinical Medicine"},{"issue":"04","key":"pone.0311208.ref030","first-page":"171","article-title":"Comparison of peroral endoscopic cardial constriction and double-dose esomeprazole on clinical efficacy of refractory gastroesophageal reflux disease","volume":"8","author":"H Cao","year":"2021","journal-title":"Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)."},{"issue":"2","key":"pone.0311208.ref031","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/ajg.2011.395","article-title":"A double-blind sham-controlled study of the effect of radiofrequency energy on symptoms and distensibility of the gastro-esophageal junction in GERD","volume":"107","author":"J Arts","year":"2012","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"pone.0311208.ref032","doi-asserted-by":"crossref","first-page":"e18610","DOI":"10.1097\/MD.0000000000018610","article-title":"Stretta procedure versus proton pump inhibitors for the treatment of nonerosive reflux disease: A 6-month follow-up.","volume":"99","author":"S He","year":"2020","journal-title":"Medicine (Baltimore)."},{"key":"pone.0311208.ref033","author":"H Cao","journal-title":"The Study on The effectiveness and Safety of Peroral Endoscopic Cardial Constriction and Anti-Reflux Mucosectomy on the Treatment of Gastroesophageal Reflux Disease"},{"issue":"09","key":"pone.0311208.ref034","first-page":"19","article-title":"The Study on The effectiveness and Safety of Peroral Endoscopic Cardial Constriction and Anti-Reflux Mucosectomy on the Treatment of Gastroesophageal Reflux Disease","volume":"26","author":"Y Chang","year":"2020","journal-title":"China Journal of Endoscopy"},{"issue":"12","key":"pone.0311208.ref035","doi-asserted-by":"crossref","first-page":"660","DOI":"10.21037\/atm-22-2071","article-title":"Clinical efficacy of endoscopic antireflux mucosectomy vs. Stretta radiofrequency in the treatment of gastroesophageal reflux disease: a retrospective, single-center cohort study.","volume":"10","author":"X Sui","year":"2022","journal-title":"Ann Transl Med."},{"key":"pone.0311208.ref036","author":"Y Zheng","journal-title":"The clinical evaluation of endoscopic anti-reflux mucosectomy and endoscopic cardial constriction ligation for the gastroesophageal reflux disease"},{"issue":"3","key":"pone.0311208.ref037","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0016-5085(03)01052-7","article-title":"Improvement of gastroesophageal reflux symptoms after radiofrequency energy: a randomized, sham-controlled trial","volume":"125","author":"DA Corley","year":"2003","journal-title":"Gastroenterology"},{"issue":"9","key":"pone.0311208.ref038","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1111\/j.1365-2036.2008.03790.x","article-title":"Clinical trial: Radiofrequency energy delivery in proton pump inhibitor-dependent gastro-oesophageal reflux disease patients.","volume":"28","author":"E Coron","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"issue":"4","key":"pone.0311208.ref039","article-title":"Phenotypes of Gastroesophageal Reflux Disease: Where Rome, Lyon, and Montreal Meet.","volume":"18","author":"K Da","year":"2020","journal-title":"Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association [Internet]."},{"issue":"2","key":"pone.0311208.ref040","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1136\/gutjnl-2023-330616","article-title":"Updates to the modern diagnosis of GERD: Lyon consensus 2.0","volume":"73","author":"CP Gyawali","year":"2024","journal-title":"Gut"},{"issue":"3","key":"pone.0311208.ref041","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1007\/s00464-010-1254-0","article-title":"A comprehensive review of laparoscopic redo fundoplication.","volume":"25","author":"DB van Beek","year":"2011","journal-title":"Surg Endosc."},{"issue":"3","key":"pone.0311208.ref042","doi-asserted-by":"crossref","first-page":"332","DOI":"10.4293\/108680810X12924466007007","article-title":"The evolution and long-term results of laparoscopic antireflux surgery for the treatment of gastroesophageal reflux disease","volume":"14","author":"CS Davis","year":"2010","journal-title":"JSLS"},{"issue":"1","key":"pone.0311208.ref043","first-page":"19","article-title":"Comparison of the Carlsson-Dent and GERD-Q questionnaires for gastroesophageal reflux disease symptom detection in a general population.","volume":"82","author":"R Contreras-Oma\u00f1a","year":"2017","journal-title":"Rev Gastroenterol Mex."},{"key":"pone.0311208.ref044","doi-asserted-by":"crossref","first-page":"102264","DOI":"10.1016\/j.coph.2022.102264","article-title":"Advancements in the use of 24-hour impedance-pH monitoring for GERD diagnosis","volume":"65","author":"E Marabotto","year":"2022","journal-title":"Curr Opin Pharmacol"},{"issue":"1","key":"pone.0311208.ref045","article-title":"Evaluation of proton pump inhibitor-resistant nonerosive reflux disease by esophageal manometry and 24-hour esophageal impedance and pH monitoring","volume":"91","author":"K O","year":"2015","journal-title":"Digestion [Internet]."},{"issue":"3","key":"pone.0311208.ref046","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1007\/s00464-016-5111-7","article-title":"Efficacy of transoral incisionless fundoplication (TIF) for the treatment of GERD: a systematic review with meta-analysis.","volume":"31","author":"X Huang","year":"2017","journal-title":"Surg Endosc."},{"issue":"06","key":"pone.0311208.ref047","first-page":"468","article-title":"Report of a case of endoscopic peroral endoscopic cardial constriction for gastroesophageal reflux disease","volume":"6","author":"H Li","year":"2013","journal-title":"Chinese Journal of Laparoscopic Surgery(Electronic Edition)."},{"issue":"15","key":"pone.0311208.ref048","doi-asserted-by":"crossref","first-page":"e0169","DOI":"10.1097\/MD.0000000000010169","article-title":"Peroral endoscopic cardial constriction in gastroesophageal reflux disease.","volume":"97","author":"HQ Hu","year":"2018","journal-title":"Medicine (Baltimore)."},{"issue":"10","key":"pone.0311208.ref049","doi-asserted-by":"crossref","first-page":"4516","DOI":"10.1007\/s00464-019-07238-3","article-title":"New treatment method for refractory gastroesophageal reflux disease (GERD): C-BLART (clip band ligation anti-reflux therapy)-a short-term study.","volume":"34","author":"S Liu","year":"2020","journal-title":"Surg Endosc."},{"issue":"7","key":"pone.0311208.ref050","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1080\/00365521.2022.2039285","article-title":"The safety and efficacy of peroral endoscopic cardial constriction in gastroesophageal reflux disease","volume":"57","author":"W Jiang","year":"2022","journal-title":"Scand J Gastroenterol"},{"issue":"12","key":"pone.0311208.ref051","first-page":"51","article-title":"A network Meta-analysis of endoscopic treatment of gastroesophageal reflux disease","volume":"28","author":"Q Xu","year":"2022","journal-title":"China Journal of Endoscopy"},{"issue":"10","key":"pone.0311208.ref052","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1097\/MCG.0000000000001757","article-title":"Endoscopic Treatment of Reflux: A Comprehensive Review.","volume":"56","author":"R Duarte Chavez","year":"2022","journal-title":"J Clin Gastroenterol."},{"issue":"2","key":"pone.0311208.ref053","doi-asserted-by":"crossref","first-page":"E133","DOI":"10.1055\/a-1031-9436","article-title":"Anti-reflux mucosal ablation (ARMA) as a new treatment for gastroesophageal reflux refractory to proton pump inhibitors: a pilot study.","volume":"8","author":"H Inoue","year":"2020","journal-title":"Endosc Int Open."},{"issue":"6","key":"pone.0311208.ref054","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.cgh.2014.10.013","article-title":"No evidence for efficacy of radiofrequency ablation for treatment of gastroesophageal reflux disease: a systematic review and meta-analysis","volume":"13","author":"S Lipka","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"pone.0311208.ref055","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1053\/j.gastro.2017.07.049","article-title":"Management of Gastroesophageal Reflux Disease.","volume":"154","author":"CP Gyawali","year":"2018","journal-title":"Gastroenterology"},{"issue":"7","key":"pone.0311208.ref056","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1007\/s00464-016-5296-9","article-title":"Radiofrequency energy delivery to the lower esophageal sphincter improves gastroesophageal reflux patient-reported outcomes in failed laparoscopic Nissen fundoplication cohort.","volume":"31","author":"M Noar","year":"2017","journal-title":"Surg Endosc."},{"issue":"5","key":"pone.0311208.ref057","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/MOG.0000000000000759","article-title":"Endoscopic approaches to gastroesophageal reflux disease.","volume":"37","author":"LY Zhang","year":"2021","journal-title":"Curr Opin Gastroenterol."},{"issue":"4","key":"pone.0311208.ref058","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/den.14169","article-title":"Endoscopic management of gastroesophageal reflux disease: Panacea for proton pump inhibitors dependent\/refractory patients.","volume":"34","author":"R Kalapala","year":"2022","journal-title":"Dig Endosc."},{"issue":"4","key":"pone.0311208.ref059","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1007\/s00464-021-08386-1","article-title":"Efficacy of different endoscopic treatments in patients with gastroesophageal reflux disease: a systematic review and network meta-analysis.","volume":"35","author":"P Xie","year":"2021","journal-title":"Surg Endosc."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0311208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T19:03:29Z","timestamp":1735671809000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0311208"}},"subtitle":[],"editor":[{"given":"Jiangtao","family":"Gou","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":59,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0311208","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]}}}