{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:15:37Z","timestamp":1793218537414,"version":"4.5.0"},"reference-count":54,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>The systematic evaluation of relevant qualitative studies on the experiences of patients with ankylosing spondylitis provides a foundation for the clinical development of personalized disease management programs for this patient category.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Multiple databases, including PubMed, Web of Science, Embase, Cochrane Library, CINAHL, Scopus, CNKI, Wanfang, CBM, and VIP, were searched for qualitative research literature on the experiences of patients with ankylosing spondylitis from the inception of databases to March 2024. Eligible studies were included, and quality was assessed using the quality evaluation standard of qualitative research at the Joanna Briggs Institute (JBI), Australia (2016). The results were integrated using the meta-aggregation approach.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 11 papers were included in the review. Four themes and 10 subthemes were synthesized: (1) difficulties in diagnosis and treatment; (2) effects of disease symptoms; (3) maladjustment of social roles; and (4) lack of support for disease response.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Medical staff should leverage the advantages of the Internet to enhance knowledge and education on ankylosing spondylitis. They should focus on patients\u2019 mental health, assist in active self-management, provide personalized interventions, promote recovery, and improve the quality of life for patients. Additionally, society should offer a diverse range of support.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0311798","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T17:33:56Z","timestamp":1729186436000},"page":"e0311798","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Experiences and perceptions of patients with ankylosing spondylitis: A systematic review and meta-synthesis of qualitative studies"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6552-914X","authenticated-orcid":true,"given":"Yu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongchi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4703-8298","authenticated-orcid":true,"given":"Lili","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,10,17]]},"reference":[{"key":"pone.0311798.ref001","article-title":"A glance into the future of diagnosis and treatment of spondyloarthritis","volume":"14","author":"V Navarro-Comp\u00e1n","year":"2022","journal-title":"Ther Adv Musculoskel"},{"issue":"1","key":"pone.0311798.ref002","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1136\/ard-2022-223296","article-title":"ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update","volume":"82","author":"S Ramiro","year":"2023","journal-title":"Ann Rheum Dis"},{"issue":"9783","key":"pone.0311798.ref003","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1016\/S0140-6736(11)60071-8","article-title":"Spondyloarthritis","volume":"377","author":"M Dougados","year":"2011","journal-title":"Lancet"},{"issue":"6","key":"pone.0311798.ref004","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1136\/ard.2009.108233","article-title":"The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection","volume":"68","author":"M Rudwaleit","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"pone.0311798.ref005","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jaut.2014.01.015","article-title":"The classification and diagnostic criteria of ankylosing spondylitis","volume":"48\u201349","author":"S P Raychaudhuri","year":"2014","journal-title":"J Autoimmun"},{"issue":"6","key":"pone.0311798.ref006","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/acr.22512","article-title":"Time trends in incidence, clinical features, and cardiovascular disease in ankylosing spondylitis over three decades: a population-based study","volume":"67","author":"KA Wright","year":"2015","journal-title":"Arthrit Care Res"},{"issue":"1","key":"pone.0311798.ref007","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3390\/jpm14010091","article-title":"Sex Bias in Diagnostic Delay: Are Axial Spondyloarthritis and Ankylosing Spondylitis Still Phantom Diseases in Women? 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