{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T23:26:53Z","timestamp":1784244413282,"version":"3.55.0"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Basic research project for basic research business expenses in Science and Technology Department, Heilongjiang Province","award":["No.2018-KYYWF-0103"],"award-info":[{"award-number":["No.2018-KYYWF-0103"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Ciprofloxacin is a widely used antibiotic in medicine and agriculture. It can cause pollution to the environment and food, thereby affecting human health.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objective<\/jats:title>\n<jats:p>This study proposes the preparation of molecular imprinted fluorescent sensors and their selective detection of ciprofloxacin, with the aim of achieving specific recognition and accurate detection of ciprofloxacin.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Rare earth metal Er<jats:sup>3+<\/jats:sup> is added to ZnS quantum dots to prepare a molecularly imprinted fluorescence sensor (MIP\/Er<jats:sup>3+<\/jats:sup>\/ZnS QDs). The effects of substance concentration, pH value, and time on the fluorescence detection intensity are analyzed to determine the optimal fluorescence detection conditions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>Experimental results showed that the sensor accurately detected ciprofloxacin with a detection limit of 31 nmol\/L and the linear range of 0.1\u201310 \u03bcmol\/L. The sensor had a recovery rate of 99.7% to 103.5% for ciprofloxacin in milk samples, with a relative standard deviation of less than 5%, indicating accurate determination of ciprofloxacin content.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Molecularly imprinted fluorescent sensors have enormous application potential in the monitoring and control of ciprofloxacin, and are of great significance for ensuring environmental and food safety.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0312156","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T18:39:16Z","timestamp":1734633556000},"page":"e0312156","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preparation of molecular imprinted fluorescence sensor based on Er3+\/ZnS QDs and its selective detection of ciprofloxacin in various matrices"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8382-1227","authenticated-orcid":true,"given":"Shuang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"pone.0312156.ref001","doi-asserted-by":"crossref","first-page":"121411","DOI":"10.1016\/j.talanta.2020.121411","article-title":"Recent advances and future trends on molecularly imprinted polymer-based fluorescence sensors with luminescent carbon dots","volume":"223","author":"S Ansari","year":"2021","journal-title":"Talanta"},{"key":"pone.0312156.ref002","doi-asserted-by":"crossref","first-page":"127397","DOI":"10.1016\/j.bmcl.2020.127397","article-title":"A highly selective and sensitive boronic acid-based sensor for detecting Pd2+ ion under mild conditions","volume":"30","author":"G Fang","year":"2020","journal-title":"Bioorg Med Chem Lett"},{"key":"pone.0312156.ref003","doi-asserted-by":"crossref","first-page":"121199","DOI":"10.1016\/j.jssc.2020.121199","article-title":"A highly sensitive multifunctional Eu-MOF sensor with pentacarboxylate for fluorescence detecting acetone, Cu2+ and Cr2O72-, and electrochemical detection of TNP","volume":"28","author":"L Gao","year":"2020","journal-title":"J. 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