{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:53:02Z","timestamp":1792684382379,"version":"4.5.0"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002489"],"award-info":[{"award-number":["UL1TR002489"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["K12 HD103085"],"award-info":[{"award-number":["K12 HD103085"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["P30 AI050410"],"award-info":[{"award-number":["P30 AI050410"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Many cisgender women in the US who have experienced incarceration are at substantial risk for HIV acquisition after they return to the community. Various network interventions have been leveraged for HIV prevention in this population. The objective of this study was to identify network and relationship determinants of influence on HIV prevention decisions, including PrEP.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We conducted interviews with a network mapping exercise with participants recruited from the social and sexual networks of women who had experienced incarceration. Participants enumerated important individuals in their lives from the past six months and provided demographic and relationship data as well as whether each relationship influenced their HIV prevention decisions. We abstracted network data from the interview transcripts and described the data set using descriptive statistics and network density graphs. To measure associations between characteristics at each level and whether a relationship was considered influential regarding PrEP decision-making, we use multiple logistic regression with random intercepts for each respondent.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>We interviewed 32 participants, average age 33.5 years (SD = 8.98), majority female (n = 28, 87.5%), white (n = 23, 71.8%), heterosexual\/straight (n = 25, 78.1%), and with a personal history of incarceration (n = 29, 90%). They reported 253 relationships (119 family, 116 friend, 18 sexual relationships). Most adult network members had used drugs or alcohol (n = 182, 80.9%), and of those, 30.8% had used them with the participant (n = 53). The mean network size was 7 (SD = 4) and network density was 52.2%. In the full model, significant positive predictors of an influential relationship included participant non-heterosexual identity (OR 27.8), older average age in the network (OR 3.9 per standard deviation), and being a current or prior sexual partner (OR 10.1). Significant negative predictors included relationships with individuals who use or had used drugs (OR 0.28), longer average relationship duration in the network (OR 0.09) and being in a network with at least one sexual partner (OR 0.2).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>There are significant positive and negative determinants of relationship influence related to PrEP at individual-, dyad-, relationship-, and network-levels. These support using nuanced network approaches to behavior change that respect and leverage the diversity of relationships that comprise the social networks of women who have experienced incarceration.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0312584","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T17:32:34Z","timestamp":1730309554000},"page":"e0312584","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Network determinants of relationship influence on HIV prevention decision-making among people in the social networks of women who have experienced incarceration in the US"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4292-3255","authenticated-orcid":true,"given":"Andrea K.","family":"Knittel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Varela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella G.","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Hulshult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie B.","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Moody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adaora A.","family":"Adimora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"issue":"8","key":"pone.0312584.ref001","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1016\/j.socscimed.2006.05.012","article-title":"Syndemics, sex and the city: understanding sexually transmitted diseases in social and cultural context","volume":"63","author":"MC Singer","year":"2006","journal-title":"Soc Sci Med"},{"issue":"3","key":"pone.0312584.ref002","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/s11524-015-9944-5","article-title":"HIV sexual risk and syndemics among women in three urban areas in the United States: Analysis from HVTN 906","volume":"92","author":"BA Koblin","year":"2015","journal-title":"J Urban Health"},{"issue":"2","key":"pone.0312584.ref003","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/phn.12056","article-title":"A syndemic model of women incarcerated in community jails","volume":"31","author":"PJ Kelly","year":"2014","journal-title":"Public Health Nurs"},{"issue":"8","key":"pone.0312584.ref004","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1080\/03630242.2014.932888","article-title":"Context of risk for HIV and sexually transmitted infections among incarcerated women in the south: individual, interpersonal, and societal factors","volume":"54","author":"CI Fogel","year":"2014","journal-title":"Women Health"},{"issue":"4","key":"pone.0312584.ref005","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1521\/aeap.2016.28.4.299","article-title":"Risk profiles of women experiencing initial and repeat incarcerations: Implications for prevention programs","volume":"28","author":"JH Herbst","year":"2016","journal-title":"AIDS Educ Prev"},{"key":"pone.0312584.ref006","first-page":"1","article-title":"HIV Risk perception and eligibility for pre-exposure prophylaxis in women involved in the criminal justice system","author":"R Rutledge","year":"2018","journal-title":"AIDS Care"},{"key":"pone.0312584.ref007","unstructured":"Price CR, Qin Y, Tracey D, Melbourne K, Altice FL, Meyer JP, editors. 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