{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:06:39Z","timestamp":1789344399737,"version":"build-2803163510"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>To investigate the risk factors for urethral stricture (US) in patients with benign prostatic hyperplasia (BPH) after transurethral resection of the prostate (TURP) and to construct a nomogram model with predictive features.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Clinical data of 400 patients with BPH who underwent TURP between June 2020 and June 2023 at Chengdu University Hospital were retrospectively collected. The data were divided into US group and no US group. Univariate and multivariate logistic regression analyses were performed sequentially to identify independent risk factors associated with US. Based on the results of the multivariate analysis, a nomogram model predicting the risk of US was constructed. We assessed the discriminatory power and calibration of the models using the C index, ROC curves, and calibration plots. In addition, we performed a decision curve analysis to validate the clinical utility of the model.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Data from a total of 400 patients were included in this study, and 35 (8.75%) were diagnosed with US. The results of univariate and multivariate analyses indicated that the following five factors age, prostate size, Preoperative indwelling catheter, Preoperative urethral dilation, Postoperative indwelling catheter time were independent influences on the risk of US. Nomogram model of US was constructed using these independent influences. The area under the curve (AUC) of the subject\u2019s operating characteristic was 0.916 (95% CI: 0.868\u20130.959), and after internal validation, the corrected C-index remained at 0.916. This further validates the accuracy and reliability of the predictive model. Calibration plots and decision curve analyses demonstrated the good clinical value of the column-line diagram model.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The nomogram model we constructed can have some guidance in clinical work.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0313557","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T18:32:40Z","timestamp":1739385160000},"page":"e0313557","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Construction of a nomogram to predict urethral stricture after transurethral resection of the prostate: A retrospective cohort study"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5622-0307","authenticated-orcid":true,"given":"Wan Mokhzani","family":"Wan Mokhter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Ashraf","family":"Mohamed Daud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"issue":"1","key":"pone.0313557.ref001","first-page":"14","article-title":"Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia (2021 Edition)","volume":"9","author":"XT Zeng","year":"2022","journal-title":"Mil Med Res"},{"key":"pone.0313557.ref002","volume-title":"Endotext","author":"N 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(Basel)"},{"issue":"4","key":"pone.0313557.ref006","doi-asserted-by":"crossref","first-page":"402","DOI":"10.5534\/wjmh.190076","article-title":"An Update on Minimally Invasive Surgery for Benign Prostatic Hyperplasia: Techniques, Risks, and Efficacy","volume":"38","author":"A Srinivasan","year":"2020","journal-title":"World J Mens Health"},{"issue":"3","key":"pone.0313557.ref007","doi-asserted-by":"crossref","first-page":"374","DOI":"10.5534\/wjmh.180106","article-title":"It\u2019s Time to Take Advantage of Robotic Assisted Simple Prostatectomy in Large Benign Prostatic Hyperplasia","volume":"37","author":"M Kim","year":"2019","journal-title":"World J Mens Health"},{"issue":"4","key":"pone.0313557.ref008","first-page":"103","article-title":"Cost-utility of minimally invasive therapies vs. pharmacotherapy as initial therapy for benign prostatic hyperplasia A Canadian healthcare payer perspective","volume":"17","author":"Y Sahakyan","year":"2023","journal-title":"Can Urol Assoc 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Urethral Strictures. StatPearls. Treasure Island (FL) ineligible companies. 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Linfang","year":"2023","journal-title":"medical equipment"},{"issue":"06","key":"pone.0313557.ref024","first-page":"1374","article-title":"Analysis of the correlation between prostate volume and operative time and urethral stricture after transurethral vaporised electrodesiccation of the prostate in elderly patients","volume":"28","author":"S Wenlong","year":"2022","journal-title":"Geriatrics and health care"},{"issue":"2","key":"pone.0313557.ref025","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1590\/S1677-5538.IBJU.2014.0500","article-title":"Analysis of risk factors leading to postoperative urethral stricture and bladder neck contracture following transurethral resection of prostate","volume":"42","author":"H Tao","year":"2016","journal-title":"Int Braz J Urol"},{"issue":"4","key":"pone.0313557.ref026","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1590\/s1677-5538.ibju.2020.99.04","article-title":"Surgical treatment of bulbar urethral strictures: tips and tricks","volume":"46","author":"G Barbagli","year":"2020","journal-title":"Int Braz J Urol"},{"issue":"6","key":"pone.0313557.ref027","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1464-410X.1991.tb15425.x","article-title":"Effect of catheter material on the incidence of urethral strictures","volume":"68","author":"GS Robertson","year":"1991","journal-title":"Br J Urol"},{"issue":"6","key":"pone.0313557.ref028","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/0090-4295(81)90462-3","article-title":"Incidence of urethral stricture after transurethral resection of prostate. 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