{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:24:57Z","timestamp":1747196697191,"version":"3.40.5"},"reference-count":50,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Purpose<\/jats:title>\n<jats:p>Global prevalence of tinnitus (15%) is rising, indicating an increase in patients seeking help for this common symptom and potentially affecting the accessibility of care. The aim of this retrospective study is twofold; describing the morbidity trends and healthcare utilization among patients with recorded tinnitus at Dutch general practices (GP), and comparing overall healthcare utilization before and after tinnitus to similar patients without recorded tinnitus.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Patients and methods<\/jats:title>\n<jats:p>Routine electronic health records data from general practices participating in Nivel Primary Care Database were used to describe trends in age- and sex-specific incidence, contact prevalence and healthcare utilization (contacts, prescriptions, and referrals to secondary care) for tinnitus from 2012 to 2021. Patients with tinnitus were matched (on sex, age, general practice) to patients without tinnitus (1:2). Healthcare use one year before and after a first GP contact for tinnitus (period) was analyzed with negative binominal (number of contacts) and logistic regression (prescriptions or referrals).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Between 2012 and 2021, tinnitus incidence increased by 33% (3.3 to 4.4 per 1000 person-years). The largest increase was observed among 20-44-years (2.6 to 3.8 per 1000 person-years). One year after the first GP contact for tinnitus, patients with tinnitus utilized healthcare more frequently than patients without tinnitus. The referral rate increased the most (OR 1.99, 95%CI 1.83\u20132.16). The year before tinnitus at the GP, patients with tinnitus had more often GP consultations (IRR 1.16, 95%CI 1.12\u20131.19) and referrals (OR 1.09, 95%CI 1.01\u20131.18) than patients without tinnitus.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Although GPs saw an increased number of patients with tinnitus, absolute numbers of patients remained low. Patients\u2019 healthcare use increased after the first tinnitus complaint at the GP, mainly for secondary care. Yet, they already used healthcare services more frequently than similar patients without tinnitus. Insight into possible explanations for these health disparities could contribute to targeted prevention.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0313630","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T18:25:26Z","timestamp":1731695126000},"page":"e0313630","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of tinnitus on Dutch general practices: A retrospective study using routine healthcare data"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4801-0385","authenticated-orcid":true,"given":"Julia M.","family":"Bes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Verheij","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart J.","family":"Knottnerus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Hek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"issue":"3","key":"pone.0313630.ref001","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3766\/jaaa.18.3.7","article-title":"The impact of tinnitus on quality of life in older adults","volume":"18","author":"DM Nondahl","year":"2007","journal-title":"J Am Acad Audiol"},{"issue":"4","key":"pone.0313630.ref002","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1177\/000348941112000402","article-title":"Prevalence of insomnia and impact of life among community elderly with tinnitus","volume":"120","author":"AO Lasisi","year":"2011","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"pone.0313630.ref003","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jpsychores.2016.03.001","article-title":"Insomnia in patients with chronic tinnitus: Cognitive and emotional distress as moderator variables","volume":"83","author":"T Cr\u00f6nlein","year":"2016","journal-title":"Journal of Psychosomatic Research"},{"issue":"9","key":"pone.0313630.ref004","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaneurol.2022.2189","article-title":"Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis","volume":"79","author":"CM Jarach","year":"2022","journal-title":"JAMA Neurology"},{"key":"pone.0313630.ref005","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.heares.2016.05.009","article-title":"A systematic review of the reporting of tinnitus prevalence and severity","volume":"337","author":"A McCormack","year":"2016","journal-title":"Hear Res"},{"issue":"5","key":"pone.0313630.ref006","doi-asserted-by":"crossref","first-page":"e0127578","DOI":"10.1371\/journal.pone.0127578","article-title":"Analysis of the Prevalence and Associated Risk Factors of Tinnitus in Adults","volume":"10","author":"HJ Kim","year":"2015","journal-title":"PLoS One"},{"key":"pone.0313630.ref007","doi-asserted-by":"crossref","first-page":"706","DOI":"10.3389\/fnins.2020.00706","article-title":"Gender-Specific Risk Factors and Comorbidities of Bothersome Tinnitus","volume":"14","author":"L Basso","year":"2020","journal-title":"Front Neurosci"},{"unstructured":"Environmental noise in Europe\u20142020\u2014European Environment Agency. 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