{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T08:49:59Z","timestamp":1766738999338,"version":"3.32.0"},"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>This in vitro study aimed to investigate the toothbrushing wear on both enamel and dentin surfaces of reference and commercially available dentifrices.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Bovine enamel and dentin blocks were initially polished and embedded within a resin composite in square shapes (10\u00d78\u00d76 mm<jats:sup>3<\/jats:sup>). Employing toothbrushes equipped with nylon bristles, a toothbrushing machine was utilized, subjecting dentin specimens (n = 36) to 500 brush cycles and enamel samples to 5000 brush cycles (n = 36). Before and after the brushing simulation (2.45-N, 180 strokes per minute), an advanced contact profilometer was employed to measure the abraded depth. The wear rates were analyzed by using One-way ANOVA with two-sided Dunnett\u2019s multiple comparisons with a control (water).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Significant variations were observed among the tested toothpaste formulations, particularly in dentin wear, where Sident and Prodent showed notably higher values (7.30 \u03bcm and 9.67 \u03bcm, respectively) compared to the water control group (0.79 \u03bcm). Prodent also induced the highest enamel wear (2.64 \u03bcm) among the toothpaste formulations, while water, Zendium, and Denttabs exhibited comparatively lower enamel wear values. Statistical analysis using One-way ANOVA with two-sided Dunnett\u2019s multiple comparisons against the control (water) confirmed these differences.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Significance<\/jats:title>\n<jats:p>Toothbrushing with water causes minimal wear on enamel and dentin tissues, suggesting the predominant effect of three-body wear when using an abrasive medium. Comparing the standard references for dentifrice abrasives, Sident and Sylodent exhibit similar wear rates, making them reliable choices for in-vitro tests. When employed in a similar frequency, the wear rate of commercial toothpaste depends more on its composition than its form (paste or tablets).<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0313637","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T18:36:51Z","timestamp":1735670211000},"page":"e0313637","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Relative abrasive potential of silica-based conventional and tablet dentifrices on enamel and dentin"],"prefix":"10.1371","volume":"19","author":[{"given":"Shaira R.","family":"Kasi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7853-5967","authenticated-orcid":true,"given":"Rafaela Oliveira","family":"Pilecco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas","family":"Saldanha da Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5412-3546","authenticated-orcid":true,"given":"Jo\u00e3o Paulo Mendes","family":"Tribst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3218-8031","authenticated-orcid":true,"given":"Cornelis Johannes","family":"Kleverlaan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutlu","family":"\u00d6zcan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert J.","family":"Feilzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"key":"pone.0313637.ref001","first-page":"28","article-title":"Evidence-based recommendation on toothpaste use.","author":"JA Cury","year":"2014","journal-title":"Braz Oral Res."},{"key":"pone.0313637.ref002","first-page":"296","article-title":"Extraction, identification, and environmental risk assessment of microplastics in commercial toothpaste.","author":"CT Madhumitha","year":"2022","journal-title":"Chemosphere."},{"key":"pone.0313637.ref003","first-page":"18","article-title":"Colgate Has 20 Billion Reasons to Make Toothpaste Tubes Recyclable First Look With Surveillance: Published online","author":"X. Warns","year":"2022"},{"key":"pone.0313637.ref004","author":"AC Tandheelkunde","year":"2020","journal-title":"Nen En Iso 11609."},{"key":"pone.0313637.ref005","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1159\/000350476","article-title":"Abrasivity testing of dentifrices\u2014challenges and current state of the art.","volume":"23","author":"C Gonz\u00e1lez-Cabezas","year":"2013","journal-title":"Monogr Oral Sci"},{"issue":"2","key":"pone.0313637.ref006","first-page":"101","article-title":"Etiology and diagnosis of tooth wear: a literature review and presentation of selected cases.","volume":"13","author":"FN Hattab","year":"2000","journal-title":"Int J Prosthodont"},{"issue":"2","key":"pone.0313637.ref007","article-title":"Toothbrushing wear resistance of stained cad\/cam ceramics.","volume":"11","author":"O Dal Piva AM de","year":"2021","journal-title":"Coatings."},{"issue":"1","key":"pone.0313637.ref008","article-title":"Comparison of mechanical property and role between enamel and dentin in the human teeth.","volume":"5","author":"KJ Chun","year":"2014","journal-title":"J Dent Biomech."},{"issue":"1","key":"pone.0313637.ref009","article-title":"Silica as a reference for laboratory dentifrice assessment methods: Multiple site collaborative study","volume":"18","author":"JJ Hefferren","year":"2007","journal-title":"Journal of Clinical Dentistry"},{"issue":"4","key":"pone.0313637.ref010","doi-asserted-by":"crossref","DOI":"10.1111\/j.1601-5037.2011.00505.x","article-title":"The role of the toothbrush in the abrasion process.","volume":"9","author":"G Tellefsen","year":"2011","journal-title":"Int J Dent Hyg."},{"issue":"10","key":"pone.0313637.ref011","doi-asserted-by":"crossref","first-page":"757","DOI":"10.5005\/jp-journals-10024-3542","article-title":"In Vitro Assessment of Different Toothbrush Designs on Enamel Surface Abrasion: A Profilometric Study.","volume":"24","author":"D Mishra","year":"2023","journal-title":"J Contemp Dent Pract."},{"issue":"4","key":"pone.0313637.ref012","doi-asserted-by":"crossref","first-page":"42","DOI":"10.48165\/ijppronline.2023.14404","article-title":"Tooth Tablets: A Review of Formulation Consideration.","volume":"14","author":"J Ankita","year":"2023","journal-title":"International Journal of Pharma Professional\u2019s Research (IJPPR)."},{"issue":"3","key":"pone.0313637.ref013","article-title":"Effect of toothpaste tablets on gloss and surface roughness of resin-based composite materials.","volume":"36","author":"K Padilla","year":"2023","journal-title":"Am J Dent."},{"key":"pone.0313637.ref014","first-page":"29","article-title":"A comparative life cycle assessment of toothpaste cream versus toothpaste tablets.","author":"S Suppipat","year":"2022","journal-title":"Sustain Prod Consum."},{"key":"pone.0313637.ref015","first-page":"148","article-title":"Impact of different brushing\/abrasion protocols on erosive tooth wear for in vitro studies","author":"LO Sakae","year":"2023","journal-title":"Arch Oral Biol"},{"key":"pone.0313637.ref016","first-page":"132","article-title":"Influence of different ultra-soft toothbrushes on erosive tooth wear.","author":"TP Pereira","year":"2023","journal-title":"J Dent."},{"key":"pone.0313637.ref017","first-page":"S0020","article-title":"Effect of brushing simulation on the wear behavior of repaired CAD-CAM restorations.","volume":"8","author":"PM Soares","year":"2024","journal-title":"Int Dent J."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T18:36:58Z","timestamp":1735670218000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313637"}},"subtitle":[],"editor":[{"given":"Geelsu","family":"Hwang","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,12,31]]},"references-count":17,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0313637","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,31]]}}}