{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:49:45Z","timestamp":1787496585046,"version":"build-2736575974"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Preeclampsia remains a formidable public health challenge, particularly in low- and middle-income countries (LMICs), where it significantly contributes to the high rates of maternal and neonatal morbidity and mortality. The advent of mobile health (mHealth) applications presents a promising avenue for enhancing the management of preeclampsia. This review protocol is designed to systematically assess the effectiveness and equity of mHealth apps in managing preeclampsia within LMICs, with a focus on clinical outcomes and the broader implications for accessibility, affordability, and cultural relevance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>To achieve the objectives of this review, a rapid review methodology will be employed, encompassing a structured search strategy to identify pertinent studies from databases such as PubMed, Cochrane Library, and Google Scholar, as well as grey literature. The inclusion criteria are set to encompass randomized controlled trials (RCTs), controlled clinical trials (CCTs), observational studies, and qualitative studies that offer insights into the effectiveness and user experience of mHealth apps for preeclampsia management. Participants in these studies will include pregnant women at risk for or diagnosed with preeclampsia, healthcare providers, and app developers. The quality of the included studies will be critically appraised using standardized tools, and data extraction will focus on study characteristics, interventions, outcomes, and equity considerations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The implications of this review are far-reaching, offering the potential to inform stakeholders including policymakers, healthcare providers, and app developers about the deployment and development of mHealth solutions for preeclampsia management in LMICs. Ultimately, the anticipated findings of this review are expected to contribute significantly to the understanding of mHealth apps\u2019 role in improving preeclampsia management and addressing healthcare disparities, thereby guiding future strategies to enhance maternal and neonatal health outcomes in LMICs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0313655","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T13:34:57Z","timestamp":1731504897000},"page":"e0313655","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness and equity of mHealth apps for preeclampsia management in LMICs: A rapid review protocol"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9134-8795","authenticated-orcid":true,"given":"Abdirahman Moallim","family":"Ibrahim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shayesteh","family":"Jahanfar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,11,13]]},"reference":[{"key":"pone.0313655.ref001","volume-title":"StatPearls","author":"SA Karrar","year":"2024"},{"issue":"14","key":"pone.0313655.ref002","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1016\/j.jacc.2020.08.014","article-title":"Preeclampsia\u2014Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review","volume":"76","author":"CW Ives","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"2 Suppl","key":"pone.0313655.ref003","doi-asserted-by":"crossref","first-page":"S844","DOI":"10.1016\/j.ajog.2021.11.1356","article-title":"The etiology of preeclampsia.","volume":"226","author":"E JUNG","year":"2022","journal-title":"Am J Obstet Gynecol."},{"issue":"3","key":"pone.0313655.ref004","doi-asserted-by":"crossref","first-page":"e14187","DOI":"10.1016\/j.heliyon.2023.e14187","article-title":"Preeclampsia: Narrative review for clinical use.","volume":"9","author":"P Vigil-De Gracia","year":"2023","journal-title":"Heliyon."},{"issue":"10","key":"pone.0313655.ref005","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.3390\/jcm8101625","article-title":"Preeclampsia: Risk Factors, Diagnosis, Management, and the Cardiovascular Impact on the Offspring.","volume":"8","author":"R Fox","year":"2019","journal-title":"J Clin Med"},{"key":"pone.0313655.ref006","doi-asserted-by":"crossref","first-page":"10","DOI":"10.12703\/b\/9-10","article-title":"Recent advances in the diagnosis and management of pre-eclampsia.","volume":"9","author":"A Hurrell","year":"2020","journal-title":"Fac Rev"},{"key":"pone.0313655.ref007","article-title":"Challenges to diagnosing and managing preeclampsia in a low-resource setting: A qualitative study of obstetric provider perspectives from Ghana |","author":"N Atluri","year":"2023","journal-title":"PLOS Global Public Health"},{"issue":"2","key":"pone.0313655.ref008","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12553-021-00523-z","article-title":"Mobile apps for self-management in pregnancy: a systematic review.","volume":"11","author":"GE Iyawa","year":"2021","journal-title":"Health Technol.1"},{"issue":"1","key":"pone.0313655.ref009","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1186\/s12884-023-05454-3","article-title":"Lessons from digital technology-enabled health interventions implemented during the coronavirus pandemic to improve maternal and birth outcomes: a global scoping review.","volume":"23","author":"IK Moise","year":"2023","journal-title":"BMC Pregnancy Childbirth."},{"key":"pone.0313655.ref010","first-page":"275","article-title":"Evaluation of mobile Apps for health promotion of pregnant women with preeclampsia.","volume":"32","author":"S Gomes ML de","year":"2019","journal-title":"Acta Paul Enferm.Jul"},{"issue":"6","key":"pone.0313655.ref011","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1109\/JBHI.2014.2301156","article-title":"Development of mHealth Applications for Pre-Eclampsia Triage","volume":"18","author":"DT Dunsmuir","year":"2014","journal-title":"IEEE J Biomed Health Inform"},{"key":"pone.0313655.ref012","article-title":"Journal of Medical Internet Research\u2014Consumer Perspectives on Maternal and Infant Health Apps: Qualitative Content Analysis [Internet].","author":"R Biviji","year":"2021"},{"key":"pone.0313655.ref013","article-title":"Smartphone-based diagnostic for preeclampsia: an mHealth solution for administering the Congo Red Dot (CRD) test in settings with limited resources","author":"SM Jonas","year":"2016","journal-title":"Journal of the American Medical Informatics Association | Oxford Academic [Internet]."},{"key":"pone.0313655.ref014","article-title":"Use of a Smartphone App to Explore Potential Underuse of Prophylactic Aspirin for Preeclampsia","author":"T Krishnamurti","year":"2021","journal-title":"| Obstetrics and Gynecology | JAMA Network Open | JAMA Network"},{"issue":"2","key":"pone.0313655.ref015","doi-asserted-by":"crossref","first-page":"e056130","DOI":"10.1136\/bmjopen-2021-056130","article-title":"Exploring digital health interventions for pregnant women at high risk for pre-eclampsia and eclampsia in low-income and-middle-income countries: a scoping review","volume":"12","author":"AS Feroz","year":"2022","journal-title":"BMJ Open"},{"issue":"1","key":"pone.0313655.ref016","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1186\/s12905-023-02825-y","article-title":"Pradhan MR. Effectiveness of mobile technology and utilization of maternal and neonatal healthcare in low and middle-income countries","volume":"23","author":"Prasenjit De","year":"2023","journal-title":"BMC Womens Health.Dec"},{"issue":"1","key":"pone.0313655.ref017","doi-asserted-by":"crossref","first-page":"e46973","DOI":"10.2196\/46973","article-title":"Exploring Maternal and Infant Health App Development and Effectiveness Research: Scoping Review.","volume":"7","author":"JC Phillips","year":"2024","journal-title":"JMIR Pediatr Parent"},{"issue":"1","key":"pone.0313655.ref018","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12884-021-03684-x","article-title":"Explaining the impact of mHealth on maternal and child health care in low- and middle-income countries: a realist synthesis.","volume":"21","author":"EM Kabongo","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"pone.0313655.ref019","article-title":"mHealth intervention to improve the continuum of maternal and perinatal care in rural Guatemala: a pragmatic, randomized controlled feasibility trial.","author":"M Boris","year":"2018","journal-title":"Reprod Health [Internet]"},{"issue":"1","key":"pone.0313655.ref020","article-title":"Incidence, trends and risk factors of preeclampsia in sub-Saharan Africa: a systematic review and meta-analysis.","volume":"11","author":"B Jikamo","year":"2023","journal-title":"PAMJ\u2014One Health [Internet]."},{"key":"pone.0313655.ref021","first-page":"481095","volume":"2011","author":"KO Osungbade","year":"2011","journal-title":"Public Health Perspectives of Preeclampsia in Developing Countries"},{"issue":"6","key":"pone.0313655.ref022","doi-asserted-by":"crossref","first-page":"e323","DOI":"10.1016\/S2214-109X(14)70227-X","article-title":"Global causes of maternal death: a WHO systematic analysis","volume":"2","author":"L Say","year":"2014","journal-title":"Lancet Glob Health"},{"key":"pone.0313655.ref023","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jclinepi.2019.10.011","article-title":"Excluding non-English publications from evidence-syntheses did not change conclusions: a meta-epidemiological study.","volume":"118","author":"B Nussbaumer-Streit","year":"2020","journal-title":"J Clin Epidemiol.Feb 1"},{"key":"pone.0313655.ref024","article-title":"Chapter 8: Assessing risk of bias in a randomized trial [Internet].","author":"JP Higgins","year":"2016"},{"key":"pone.0313655.ref025","first-page":"372","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.","author":"MJ Page","year":"2021","journal-title":"BMJ"},{"issue":"4","key":"pone.0313655.ref026","doi-asserted-by":"crossref","first-page":"100806","DOI":"10.1016\/j.hlpt.2023.100806","article-title":"Current evidence on the use of mHealth approaches in Sub-Saharan Africa: A scoping review.","volume":"12","author":"GT Aboye","year":"2023","journal-title":"Health Policy Technol."},{"key":"pone.0313655.ref027","article-title":"Assessing the impact of mHealth interventions in low- and middle-income countries\u2013what has been shown to work?","author":"CS Hall","year":"2014","journal-title":"Glob Health Action [Internet]."},{"key":"pone.0313655.ref028","article-title":"Mobile health solutions: An opportunity for rehabilitation in low- and middle income countries?","volume":"10","author":"B Bonnech\u00e8re","year":"2022","journal-title":"Front Public Health [Internet]."},{"issue":"1","key":"pone.0313655.ref029","doi-asserted-by":"crossref","first-page":"e42161","DOI":"10.2196\/42161","article-title":"Digital Health Technologies for Maternal and Child Health in Africa and Other Low- and Middle-Income Countries: Cross-disciplinary Scoping Review With Stakeholder Consultation.","volume":"25","author":"S Till","year":"2023","journal-title":"J Med Internet Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T13:35:04Z","timestamp":1731504904000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313655"}},"subtitle":[],"editor":[{"given":"Jonathan","family":"Bayuo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,11,13]]},"references-count":29,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0313655","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,13]]}}}