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However, the use of hMSCs in research and clinical medicine is limited by a lack of information pertaining to their donor-specific functional attributes. In this study, we compared the characteristics of same-donor derived placenta (PL) and Wharton\u2019s jelly (WJ)-derived hMSCs, we also compared their mechanism of action in a skeletal muscle disease <jats:italic>in vitro<\/jats:italic> model. The same-donor-derived hWJ- and hPL-MSCs exhibited typical hMSC characteristics. However, GRO-\u03b1 was differentially expressed in hWJ- and hPL-MSCs. hWJ-MSCs, which secreted a high amount of GRO-\u03b1, displayed a higher ability to inhibit necroptosis in skeletal muscle cells than hPL-MSCs. This demonstrates the anti-necroptotic therapeutic effect of GRO-\u03b1 in the skeletal muscle cell death model. Furthermore, GRO-\u03b1 also exhibited the anti-necroptotic effect in a Duchenne muscular dystrophy (DMD) mouse model. Considering their potential to inhibit necroptosis in skeletal muscle cells, hWJ-MSCs and the derived GRO-\u03b1 are novel treatment options for skeletal muscle diseases such as DMD.<\/jats:p>","DOI":"10.1371\/journal.pone.0313693","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T18:41:38Z","timestamp":1733164898000},"page":"e0313693","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anti-necroptotic effects of human Wharton\u2019s jelly-derived mesenchymal stem cells in skeletal muscle cell death model via secretion of GRO-\u03b1"],"prefix":"10.1371","volume":"19","author":[{"given":"Sang Eon","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Jin","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Jeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jang Bin","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Jeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suk-joo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo-young","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyu Ha","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4420-9968","authenticated-orcid":true,"given":"Hong Bae","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Wook","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,12,2]]},"reference":[{"issue":"1","key":"pone.0313693.ref001","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/s13287-017-0716-x","article-title":"Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue","volume":"8","author":"L Xu","year":"2017","journal-title":"Stem Cell Res Ther"},{"key":"pone.0313693.ref002","doi-asserted-by":"crossref","first-page":"4285215","DOI":"10.1155\/2016\/4285215","article-title":"Mesenchymal Stromal Cells and Tissue-Specific Progenitor Cells: Their Role in Tissue Homeostasis","volume":"2016","author":"A Klimczak","year":"2016","journal-title":"Stem Cells Int"},{"key":"pone.0313693.ref003","doi-asserted-by":"crossref","first-page":"4709572","DOI":"10.1155\/2016\/4709572","article-title":"Mesenchymal Stem Cells Derived from Dental Pulp: A Review","volume":"2016","author":"E Ledesma-Martinez","year":"2016","journal-title":"Stem Cells Int"},{"issue":"7","key":"pone.0313693.ref004","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1177\/0963689719837897","article-title":"The Pros and Cons of Mesenchymal Stem Cell-Based Therapies","volume":"28","author":"A Musial-Wysocka","year":"2019","journal-title":"Cell Transplant"},{"issue":"4","key":"pone.0313693.ref005","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1159\/000142333","article-title":"Mesenchymal Stem Cells\u2014Sources and Clinical Applications","volume":"35","author":"H Klingemann","year":"2008","journal-title":"Transfus Med Hemother"},{"issue":"8","key":"pone.0313693.ref006","doi-asserted-by":"crossref","first-page":"784","DOI":"10.3390\/cells8080784","article-title":"Mesenchymal Stem Cell Migration and Tissue Repair","volume":"8","author":"X Fu","year":"2019","journal-title":"Cells"},{"issue":"10","key":"pone.0313693.ref007","doi-asserted-by":"crossref","first-page":"2614","DOI":"10.1002\/stem.187","article-title":"Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging","volume":"27","author":"S Kidd","year":"2009","journal-title":"Stem Cells"},{"key":"pone.0313693.ref008","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12861-015-0094-5","article-title":"The developmental basis of mesenchymal stem\/stromal cells (MSCs)","volume":"15","author":"G. 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niche formation","volume":"125","author":"A Reinisch","year":"2015","journal-title":"Blood"},{"key":"pone.0313693.ref039","doi-asserted-by":"crossref","first-page":"4356359","DOI":"10.1155\/2020\/4356359","article-title":"Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis","volume":"2020","author":"S Maacha","year":"2020","journal-title":"Stem Cells Int"},{"key":"pone.0313693.ref040","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41536-019-0070-y","article-title":"Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential","volume":"4","author":"D Kehl","year":"2019","journal-title":"NPJ Regen Med"},{"issue":"11","key":"pone.0313693.ref041","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1111\/jog.13432","article-title":"Comparison of the paracrine activity of mesenchymal stem cells derived from human umbilical cord, amniotic membrane and adipose tissue","volume":"43","author":"FA Dabrowski","year":"2017","journal-title":"J Obstet Gynaecol Res"},{"issue":"19","key":"pone.0313693.ref042","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1089\/scd.2013.0016","article-title":"Mesenchymal stromal cell characteristics vary depending on their origin","volume":"22","author":"H Wegmeyer","year":"2013","journal-title":"Stem Cells Dev"},{"issue":"3","key":"pone.0313693.ref043","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/cvr\/cvr328","article-title":"Amniotic mesenchymal stem cells have robust angiogenic properties and are effective in treating hindlimb ischaemia","volume":"93","author":"SW Kim","year":"2012","journal-title":"Cardiovasc Res"},{"issue":"31","key":"pone.0313693.ref044","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1038\/sj.onc.1203687","article-title":"Growth regulated oncogene-alpha expression by murine squamous cell carcinoma promotes tumor growth, metastasis, leukocyte infiltration and angiogenesis by a host CXC 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Basic types and mechanisms of cell death","volume":"117","author":"LM Buja","year":"1993","journal-title":"Arch Pathol Lab Med"},{"issue":"1","key":"pone.0313693.ref052","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s12974-018-1235-0","article-title":"Necroptosis: a regulated inflammatory mode of cell death","volume":"15","author":"YK Dhuriya","year":"2018","journal-title":"J Neuroinflammation"},{"issue":"5","key":"pone.0313693.ref053","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1038\/s41423-020-00630-3","article-title":"Necroptosis, pyroptosis and apoptosis: an intricate game of cell death","volume":"18","author":"D Bertheloot","year":"2021","journal-title":"Cell Mol Immunol"},{"issue":"4","key":"pone.0313693.ref054","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/01926230701320337","article-title":"Apoptosis: a review of programmed cell death","volume":"35","author":"S. Elmore","year":"2007","journal-title":"Toxicol Pathol"},{"issue":"2","key":"pone.0313693.ref055","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/nrm.2016.149","article-title":"Necroptosis in development, inflammation and disease","volume":"18","author":"R Weinlich","year":"2017","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"15","key":"pone.0313693.ref056","doi-asserted-by":"crossref","first-page":"e128834","DOI":"10.1172\/jci.insight.128834","article-title":"Necroptosis: a crucial pathogenic mediator of human disease","volume":"4","author":"ME Choi","year":"2019","journal-title":"JCI Insight"},{"issue":"2","key":"pone.0313693.ref057","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1016\/j.nmd.2017.06.029","article-title":"Necroptosis, a programmed form of necrosis, participates in muscle degeneration in Duchenne muscular dystrophy","volume":"27","author":"M Bencze","year":"2017","journal-title":"Neuromuscular Disorders"},{"issue":"7","key":"pone.0313693.ref058","doi-asserted-by":"crossref","first-page":"107652","DOI":"10.1016\/j.celrep.2020.107652","article-title":"Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles","volume":"31","author":"K Sreenivasan","year":"2020","journal-title":"Cell Rep"},{"issue":"1","key":"pone.0313693.ref059","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1038\/s41467-018-06057-9","article-title":"Necroptosis mediates myofibre death in dystrophin-deficient mice","volume":"9","author":"JE Morgan","year":"2018","journal-title":"Nat Commun"},{"issue":"9","key":"pone.0313693.ref060","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/sj.embor.7400221","article-title":"Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment","volume":"5","author":"KJ Nowak","year":"2004","journal-title":"EMBO Rep"},{"issue":"9307","key":"pone.0313693.ref061","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0140-6736(02)07815-7","article-title":"The muscular dystrophies","volume":"359","author":"AEH Emery","year":"2002","journal-title":"The Lancet"},{"issue":"4","key":"pone.0313693.ref062","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0092-8674(00)80533-4","article-title":"Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy","volume":"90","author":"RM Grady","year":"1997","journal-title":"Cell"},{"issue":"1","key":"pone.0313693.ref063","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41572-021-00248-3","article-title":"Duchenne muscular dystrophy","volume":"7","author":"D Duan","year":"2021","journal-title":"Nat Rev Dis Primers"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T18:42:03Z","timestamp":1733164923000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313693"}},"subtitle":[],"editor":[{"given":"Atsushi","family":"Asakura","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,12,2]]},"references-count":63,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0313693","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2024,12,2]]}}}