{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:22:50Z","timestamp":1788355370990,"version":"build-2803163510"},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Psychology Research Unit","award":["code 010264-10 and P10370-10"],"award-info":[{"award-number":["code 010264-10 and P10370-10"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Chronic health conditions often affect the lives of family members as well as the patient themselves. The current study aimed to explore the experiences of partners of individuals with diabetes and chronic kidney disease (CKD) who received a simultaneous pancreas and kidney transplant (SPKT) to understand the wider impact of SPKTs. Eight partners of recipients of SPKT were interviewed about their experiences before and after the transplant. Interviews were transcribed verbatim and analysed thematically. Participants described how they navigated life with an unwell partner; sub-themes included a) living with pervasive worry, b) the challenge of enhanced responsibilities, and c) the buffering effect of social support. Diabetes complications, such as the experience of severe hypoglycaemia, particularly fuelled worry. Participants felt great relief after their partner\u2019s successful transplant but also faced certain realities around the potential for their partner\u2019s health to deteriorate again. The study highlights the impact of diabetes and CKD on patients\u2019 families and the wider benefit of transplantation, not just for the patient. The pancreas transplant, in addition to the kidney, relieved partners of their worry about hypoglycaemic events and the development of diabetes complications. Partners may benefit from being encouraged to seek support and to maintain their own health and wellbeing.<\/jats:p>","DOI":"10.1371\/journal.pone.0313907","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T18:28:19Z","timestamp":1731954499000},"page":"e0313907","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Simultaneous pancreas and kidney transplantation: A qualitative study of partners\u2019 experiences"],"prefix":"10.1371","volume":"19","author":[{"given":"Katie E. J.","family":"Hann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Cinnirella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7774-0563","authenticated-orcid":true,"given":"Andrea","family":"Gibbons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"pone.0313907.ref001","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.mpmed.2015.05.005","article-title":"Epidemiology and causes of chronic kidney disease","volume":"43","author":"PD Evans","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"pone.0313907.ref002","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/S0140-6736(16)32064-5","article-title":"Morton RL, Masson P. Chronic kidney disease","volume":"389","author":"AC Webster","year":"2017","journal-title":"Lancet"},{"key":"pone.0313907.ref003","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1177\/104973202129119928","article-title":"You can\u2019t cure it so you have to endure it\u201d: The experience of adaptation to diabetic renal disease","volume":"12","author":"N King","year":"2002","journal-title":"Qual Health Res"},{"key":"pone.0313907.ref004","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1755-6686.2012.00278.x","article-title":"Exploring the process of adjusting to diabetic kidney disease","volume":"38","author":"K Reid","year":"2012","journal-title":"J Ren Care"},{"key":"pone.0313907.ref005","doi-asserted-by":"crossref","first-page":"e023507","DOI":"10.1136\/bmjopen-2018-023507","article-title":"Work of being an adult patient with chronic kidney disease: A systematic review of qualitative studies","volume":"8","author":"J Roberti","year":"2018","journal-title":"BMJ Open"},{"key":"pone.0313907.ref006","first-page":"1","article-title":"Patient perspectives on quality of life with uncontrolled type 1 diabetes mellitus: A systematic review and qualitative meta-synthesis","volume":"15","author":"M Vanstone","year":"2015","journal-title":"Ont Health Technol Assess Ser"},{"key":"pone.0313907.ref007","first-page":"1","article-title":"Daily life after a kidney-pancreas transplantation","volume":"12","author":"K Dahl","year":"2018","journal-title":"Nor J Clin Nursing\/Sykepleien Forsk"},{"key":"pone.0313907.ref008","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1111\/tri.13677","article-title":"Changes in quality of life, health status and other patient\u2010reported outcomes following simultaneous pancreas and kidney transplantation (SPKT): A quantitative and qualitative analysis within a UK\u2010wide programmme","volume":"33","author":"A Gibbons","year":"2020","journal-title":"Transpl Int"},{"key":"pone.0313907.ref009","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2147\/PPA.S35144","article-title":"Impact of simultaneous pancreas-kidney transplantation: Patients\u2019 perspectives","volume":"6","author":"PI Pera","year":"2012","journal-title":"Patient Prefer Adherence"},{"key":"pone.0313907.ref010","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1177\/1359105318817356","article-title":"Couples living with type 1 diabetes: An integrative review of the impacts on health and wellbeing","volume":"26","author":"R Messina","year":"2018","journal-title":"J Health Psychol"},{"key":"pone.0313907.ref011","first-page":"18","article-title":"The experience of partners of adults with type 1 diabetes: An integrative review","author":"R Whittemore","year":"2018","journal-title":"Curr Diabetes Rep"},{"key":"pone.0313907.ref012","doi-asserted-by":"crossref","first-page":"109","DOI":"10.2337\/dc13-1154","article-title":"Experiences, views, and support needs of family members of people with hypoglycemia unawareness: Interview study","volume":"37","author":"J Lawton","year":"2014","journal-title":"Diabetes Care"},{"key":"pone.0313907.ref013","article-title":"Everyday living with diabetes described by family members of adult people with type 1 diabetes","author":"TM Rintala","year":"2013","journal-title":"Int J Family Med"},{"key":"pone.0313907.ref014","first-page":"215","article-title":"Lived experience of significant others of persons with diabetes","volume":"16","author":"R St\u00f6dberg","year":"2012","journal-title":"J Clin Nurs"},{"key":"pone.0313907.ref015","first-page":"75","article-title":"The experience of spouses caring for a person on home haemodialysis: An ethnography","volume":"4","author":"AE Blogg","year":"2008","journal-title":"Ren Soc Australas J"},{"key":"pone.0313907.ref016","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.xkme.2019.06.001","article-title":"Family members\u2019 experiences with dialysis and kidney transplantation","volume":"1","author":"N DePasquale","year":"2019","journal-title":"Kidney Med"},{"key":"pone.0313907.ref017","first-page":"67","article-title":"The impact of end-stage kidney disease (ESKD) on close persons: A literature review","volume":"1","author":"J Low","year":"2008","journal-title":"Nephrol Dial Transplant Plus"},{"key":"pone.0313907.ref018","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/scs.12283","article-title":"Caring in an atmosphere of uncertainty: Perspectives and experiences of caregivers of peoples undergoing haemodialysis in Iran","volume":"30","author":"L Rabiei","year":"2016","journal-title":"Scand J Caring Sci"},{"key":"pone.0313907.ref019","first-page":"193","article-title":"Progressive exhaustion: A qualitative study on the experiences of Iranian family caregivers regarding patients undergoing hemodialysis","volume":"5","author":"S Salehitali","year":"2018","journal-title":"Int J Nurs Sci"},{"key":"pone.0313907.ref020","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1093\/ndt\/gfh717","article-title":"Partners\u2019 concerns, needs and expectations in ESRD: Results of the CODIT Study","volume":"20","author":"E Morelon","year":"2005","journal-title":"Nephrol Dial Transplant"},{"key":"pone.0313907.ref021","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.transproceed.2015.04.054","article-title":"Caregiver burden, anxiety, depression, and sleep quality differences in caregivers of hemodialysis patients compared with renal transplant patients","volume":"47","author":"U Av\u015far","year":"2015","journal-title":"Transplant Proc"},{"key":"pone.0313907.ref022","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.transproceed.2013.03.004","article-title":"Psychological and emotional status, and caregiver burden in caregivers of patients with peritoneal dialysis compared with caregivers of patients with renal transplantation","volume":"45","author":"U Av\u015far","year":"2013","journal-title":"Transplant Proc"},{"key":"pone.0313907.ref023","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1046\/j.1365-2648.2000.01404.x","article-title":"Coping strategies and health\u2010related quality of life among spouses of continuous ambulatory peritoneal dialysis, haemodialysis, and transplant patients","volume":"31","author":"R Lindqvist","year":"2000","journal-title":"J Adv Nurs"},{"key":"pone.0313907.ref024","doi-asserted-by":"crossref","first-page":"e566","DOI":"10.1097\/TXD.0000000000000998","article-title":"Kidney dyads: Caregiver burden and relationship strain among partners of dialysis and transplant patients","volume":"6","author":"SEVP Rasmussen","year":"2020","journal-title":"Transplant Direct"},{"key":"pone.0313907.ref025","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1177\/152692481002000406","article-title":"Spouse caregivers of kidney transplant patients: Quality of life and psychosocial outcomes","volume":"20","author":"JR Rodrigue","year":"2010","journal-title":"Prog Transplant"},{"key":"pone.0313907.ref026","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-Item Short-Form Health Survey (SF-36): I. Conceptual framework and item selection","volume":"30","author":"JE Ware","year":"1992","journal-title":"Med Care"},{"key":"pone.0313907.ref027","volume-title":"Manual for the Profile of Mood States Scale (POMS)","author":"DM McNair","year":"1981"},{"key":"pone.0313907.ref028","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1093\/geronj\/38.3.344","article-title":"Validation of a caregiver strain index","volume":"38","author":"BC Robinson","year":"1983","journal-title":"J Gerontol"},{"key":"pone.0313907.ref029","volume-title":"Patient-reported outcomes of chronic kidney disease and diabetes treatments, including transplantation","author":"K. Hann","year":"2022"},{"key":"pone.0313907.ref030","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1097\/ACM.0000000000000388","article-title":"Standards for reporting qualitative research: A synthesis of recommendations","volume":"89","author":"BC O\u2019Brien","year":"2014","journal-title":"Acad Med"},{"key":"pone.0313907.ref031","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"V Braun","year":"2006","journal-title":"Qual Res Psychol"},{"key":"pone.0313907.ref032","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1080\/2159676X.2019.1628806","article-title":"Reflecting on reflexive thematic analysis","volume":"11","author":"V Braun","year":"2019","journal-title":"Qual Res Sport Exerc Heal"},{"key":"pone.0313907.ref033","first-page":"84","volume-title":"Anal. Qual. data Psychol.","author":"V Clarke","year":"2015","edition":"2"},{"key":"pone.0313907.ref034","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1348\/000712600161646","article-title":"Objectivity and reliability in qualitative analysis: Realist, contextualist and radical constructionist epistemologies","volume":"91","author":"A Madill","year":"2000","journal-title":"Br J Psychol"},{"key":"pone.0313907.ref035","first-page":"3","article-title":"Fear of hypoglycemia: A review","volume":"5","author":"L. Gonder-Frederick","year":"2013","journal-title":"Diabet Hypoglycemia"},{"key":"pone.0313907.ref036","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1089\/dia.2015.0451","article-title":"Emotional distress in the partners of type 1 diabetes adults: Worries about hypoglycemia and other key concerns","volume":"18","author":"WH Polonsky","year":"2016","journal-title":"Diabetes Technol Ther"},{"key":"pone.0313907.ref037","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.2215\/CJN.00800209","article-title":"Frequency of hypoglycemia and its significance in chronic kidney disease","volume":"4","author":"MF Moen","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"pone.0313907.ref038","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1471-6712.2006.00400.x","article-title":"Health in everyday life among spouses of haemodialysis patients: A content analysis","volume":"20","author":"K Ziegert","year":"2006","journal-title":"Scand J Caring Sci"},{"key":"pone.0313907.ref039","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1037\/0022-3514.61.3.404","article-title":"Couples coping with a myocardial infarction: A contextual perspective on wives\u2019 distress","volume":"61","author":"JC Coyne","year":"1991","journal-title":"J Pers Soc Psychol"},{"key":"pone.0313907.ref040","volume-title":"Stress, appraisal, and coping","author":"RS Lazarus","year":"1984"},{"key":"pone.0313907.ref041","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.cpr.2015.07.002","article-title":"Dyadic coping and relationship satisfaction: A meta-analysis","volume":"42","author":"MK Falconier","year":"2015","journal-title":"Clin Psychol Rev"},{"key":"pone.0313907.ref042","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1053\/j.ajkd.2018.09.006","article-title":"Burden of care and quality of life among caregivers for adults receiving maintenance dialysis: A systematic review","volume":"73","author":"E. L. Gilbertson","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"pone.0313907.ref043","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1037\/0033-2909.130.4.601","article-title":"Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry","volume":"130","author":"SC Segerstrom","year":"2004","journal-title":"Psychol Bull"},{"key":"pone.0313907.ref044","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.0963-7214.2004.01301004.x","article-title":"Is caregiving a risk factor for illness?","volume":"13","author":"PP Vitaliano","year":"2004","journal-title":"Curr Dir Psychol Sci"},{"key":"pone.0313907.ref045","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/jorc.12322","article-title":"Family caregiver\u2019s burden and the social support for older patients undergoing peritoneal dialysis","volume":"46","author":"X Tao","year":"2020","journal-title":"J Ren Care"},{"key":"pone.0313907.ref046","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/j.1365-2702.2006.01330.x","article-title":"The experiences of loneliness, depression, and social support of Turkish patients with continuous ambulatory peritoneal dialysis and their caregivers","volume":"15","author":"T Asti","year":"2006","journal-title":"J Clin Nurs"},{"key":"pone.0313907.ref047","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1177\/0091217420913388","article-title":"Burden, quality of life, anxiety, and depressive symptoms among caregivers of hemodialysis patients: The role of social support","volume":"55","author":"M Shukri","year":"2020","journal-title":"Int J Psychiatry Med"},{"key":"pone.0313907.ref048","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1111\/j.1369-7625.2009.00568.x","article-title":"Exploring kidney patients\u2019 experiences of receiving individual peer support","volume":"12","author":"J Hughes","year":"2009","journal-title":"Heal Expect"},{"key":"pone.0313907.ref049","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/hex.12348","article-title":"Peer support for CKD patients and carers: Overcoming barriers and facilitating access","volume":"19","author":"F Taylor","year":"2016","journal-title":"Heal Expect"},{"key":"pone.0313907.ref050","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1080\/14780887.2020.1769238","article-title":"One size fits all? What counts as quality practice in (reflexive) thematic analysis?","volume":"18","author":"V Braun","year":"2021","journal-title":"Qual Res Psychol"},{"key":"pone.0313907.ref051","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1037\/hea0000141","article-title":"Are patient and relationship variables associated with participation of intimate partners in couples research?","volume":"34","author":"M Hagedoorn","year":"2015","journal-title":"Heal Psychol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T18:28:35Z","timestamp":1731954515000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0313907"}},"subtitle":[],"editor":[{"given":"Edward","family":"Zimbudzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,11,18]]},"references-count":51,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0313907","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,18]]}}}