{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T12:41:25Z","timestamp":1789130485531,"version":"build-2803163510"},"reference-count":67,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011929","name":"Foundation for Food and Agriculture Research","doi-asserted-by":"publisher","award":["FF-NIA20-0000000062"],"award-info":[{"award-number":["FF-NIA20-0000000062"]}],"id":[{"id":"10.13039\/100011929","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Grape sour rot (GSR) is a disease complex involving fungi and bacteria that can cause significant yield losses of susceptible varieties. It is widely spread in the eastern U.S. and other grape-growing regions globally. Previous studies suggest that damaged fruit skin and feeding insects like <jats:italic>Drosophila<\/jats:italic> spp. are required for the disease to occur. Current control strategies for the management of sour rot are not sustainable, and research on the implications of chemical management of the disease on microbiome diversity is scarce. Our aim was to: i) investigate the effect of insecticide application and netting treatment on the microbiota of GSR-susceptible and tolerant grape varieties; and ii) identify the core microbial assemblages potentially associated with grape sour rot development in Maryland. Using a combined analysis of culture-dependent and independent data, we found that microbiota diversity of healthy grape berries did not change with netting, insecticide application, and between varieties. There was a significant difference in bacterial diversity between healthy and sour rot-affected berries. <jats:italic>Komagataeibacter<\/jats:italic> was consistently associated with infected berries followed by <jats:italic>Acetobacter<\/jats:italic> and <jats:italic>Gluconobacter<\/jats:italic>. This is the first study to report the association of <jats:italic>Komagataeibacter<\/jats:italic> with GSR-infected berries. It is thus imperative to investigate its role alongside that of other identified core microbiomes in sour rot development. <jats:italic>Candida<\/jats:italic> and <jats:italic>Pichia<\/jats:italic> were also consistent genera in infected berries. Several unidentified <jats:italic>Candida<\/jats:italic>, <jats:italic>Pichia<\/jats:italic>, and other fungal species from infected berries formed the core mycobiomes and it would be worth investigating their involvement in GSR development in Mid-Atlantic vineyards.<\/jats:p>","DOI":"10.1371\/journal.pone.0314397","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T18:36:47Z","timestamp":1738867007000},"page":"e0314397","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparative analysis of grape berry microbiota uncovers sour rot associates from a Maryland vineyard"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6250-9107","authenticated-orcid":true,"given":"Blaise","family":"Jumbam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magaly","family":"Toro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1567-0843","authenticated-orcid":true,"given":"Mengjun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"pone.0314397.ref001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jare.2021.12.008","article-title":"The microbiota of the grapevine holobiont: A key component of plant health","volume":"40","author":"P Bettenfeld","year":"2022","journal-title":"J Adv Res [Internet]"},{"issue":"1","key":"pone.0314397.ref002","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1073\/pnas.1320471110","article-title":"Microbial terroir for wine grapes","volume":"111","author":"JA Gilbert","year":"2014","journal-title":"Proc Natl Acad Sci [Internet]"},{"issue":"1","key":"pone.0314397.ref003","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/02648725.2006.10648084","article-title":"Endophytic Bacteria and their Potential Application to Improve the Phytoremediation of Contaminated Environments","volume":"23","author":"C Mastretta","year":"2006","journal-title":"Biotechnol Genet Eng Rev [Internet]"},{"issue":"6","key":"pone.0314397.ref004","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1094\/PHYTO-09-17-0306-R","article-title":"Biological Control of Botrytis cinerea: Interactions with Native Vineyard Yeasts from Washington State","volume":"108","author":"X Wang","year":"2018","journal-title":"Phytopathology\u00ae [Internet]"},{"issue":"6","key":"pone.0314397.ref005","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/1567-1364.12054","article-title":"Selection of Botrytis cinerea and Saccharomyces cerevisiae strains for the improvement and valorization of Italian passito style wines","volume":"13","author":"M Azzolini","year":"2013","journal-title":"FEMS Yeast Res [Internet]"},{"issue":"7","key":"pone.0314397.ref006","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/j.1567-1364.2008.00399.x","article-title":"Sour rot-damaged grapes are sources of wine spoilage yeasts","volume":"8","author":"A Barata","year":"2008","journal-title":"FEMS Yeast Res [Internet]"},{"issue":"12","key":"pone.0314397.ref007","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1094\/PHYTO-03-18-0098-R","article-title":"Grape Sour Rot: A Four-Way Interaction Involving the Host, Yeast, Acetic Acid Bacteria, and Insects","volume":"108","author":"ME Hall","year":"2018","journal-title":"Phytopathology\u00ae [Internet]"},{"key":"pone.0314397.ref008","unstructured":"Grape Sour Rot [Internet]. 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