{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:25:23Z","timestamp":1791390323561,"version":"4.3.3"},"reference-count":58,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"publisher","award":["Grant R21TW012650"],"award-info":[{"award-number":["Grant R21TW012650"]}],"id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>This study will evaluate the feasibility and preliminary effectiveness of the COACH (Community Health Worker Optimization of Antihypertensive Care in HIV) intervention, which integrates hypertension management into existing HIV care for people living with HIV (PLWH) in Tanzania.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The study will be conducted at two HIV Care and Treatment Centers (CTCs) in Tanzania. In a single-arm pre-post feasibility trial, 100 PLWH with hypertension will be enrolled and will receive the six-month intervention. The COACH intervention includes six monthly hypertension educational sessions delivered by community health workers (CHWs) and integrated within HIV CTC visits, monthly blood pressure monitoring, follow up care coordination, fully subsidized antihypertensive medications, a standardized antihypertensive treatment algorithm, and training for providers. The intervention\u2019s implementation outcomes will be evaluated using the Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) framework, and the primary study outcome (reach of the intervention) will be the proportion of all scheduled intervention sessions attended by participants, a measure of feasibility. Secondary clinical effectiveness outcomes will include adherence to antihypertensive medication, blood pressure control, body mass index, cardiovascular risk, and hypertension knowledge.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Significance<\/jats:title>\n<jats:p>The COACH intervention has the potential to significantly improve hypertension management among PLWH in Tanzania by leveraging the existing HIV care infrastructure and CHWs. This study will provide crucial insights into the feasibility and potential effectiveness of the intervention in integrating hypertension care into HIV services, informing larger-scale implementation and policy changes in Tanzania and other resource-limitted settings.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Trial registration<\/jats:title>\n<jats:p>Clinical trials.gov Identifer: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT06503991\" xlink:type=\"simple\">NCT06503991<\/jats:ext-link>.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0315027","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T18:32:29Z","timestamp":1734460349000},"page":"e0315027","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Community Health Worker Optimization of Antihypertensive Care in HIV (COACH): Study protocol for a pilot trial of an intervention to improve hypertension care among Tanzanians with HIV"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7284-9826","authenticated-orcid":true,"given":"Wai Yan","family":"Min Htike","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7587-224X","authenticated-orcid":true,"given":"Preeti","family":"Manavalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Wanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelvin","family":"Haukila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandina T.","family":"Mmbaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis M.","family":"Sakita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rennyda","family":"Zebedayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Gwasma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tazeen","family":"Jafar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayden B.","family":"Bosworth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan M.","family":"Thielman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7396-4789","authenticated-orcid":true,"given":"Julian T.","family":"Hertz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"pone.0315027.ref001","article-title":"The HIV Epidemic in Sub-Saharan Africa is Aging: Evidence from the Demographic and Health Surveys in Sub-Saharan Africa","author":"HK Vollmer S","year":"2017","journal-title":"AIDS Behav"},{"issue":"Suppl 1","key":"pone.0315027.ref002","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1097\/QAD.0000000000001888","article-title":"Noncommunicable diseases among HIV-infected persons in low-income and middle-income countries: a systematic review and meta-analysis","volume":"32","author":"P Patel","year":"2018","journal-title":"Aids"},{"issue":"10159","key":"pone.0315027.ref003","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"1980\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories","year":"2018","journal-title":"Lancet"},{"issue":"10226","key":"pone.0315027.ref004","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0140-6736(19)32008-2","article-title":"Modifiable risk factors, cardiovascular disease, and mortality in 155\u2008722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study.","volume":"395","author":"S Yusuf","year":"2020","journal-title":"Lancet"},{"issue":"9","key":"pone.0315027.ref005","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1097\/HJH.0b013e328362bad7","article-title":"Hypertension-related diseases as a common cause of hospital mortality in Tanzania: a 3-year prospective study","volume":"31","author":"RN Peck","year":"2013","journal-title":"J Hypertens"},{"issue":"8","key":"pone.0315027.ref006","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1111\/jch.13929","article-title":"Hypertension burden and challenges across the hypertension treatment cascade among adults enrolled in HIV care in northern Tanzania","volume":"22","author":"P Manavalan","year":"2020","journal-title":"J Clin Hypertens (Greenwich)."},{"key":"pone.0315027.ref007","doi-asserted-by":"crossref","first-page":"4103604","DOI":"10.1155\/2019\/4103604","article-title":"Hypertension in HIV-Infected Patients Receiving Antiretroviral Therapy in Northeast Ethiopia.","volume":"2019","author":"T Fiseha","year":"2019","journal-title":"Int J Hypertens"},{"issue":"7","key":"pone.0315027.ref008","doi-asserted-by":"crossref","first-page":"e25364","DOI":"10.1002\/jia2.25364","article-title":"HIV, antiretroviral therapy and non-communicable diseases in sub-Saharan Africa: empirical evidence from 44 countries over the period 2000 to 2016","volume":"22","author":"L Coetzee","year":"2019","journal-title":"J Int AIDS Soc"},{"issue":"10","key":"pone.0315027.ref009","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1097\/QAD.0000000000002930","article-title":"Implications of weight gain with newer anti-retrovirals: 10-year predictions of cardiovascular disease and diabetes","volume":"35","author":"K McCann","year":"2021","journal-title":"Aids"},{"issue":"8","key":"pone.0315027.ref010","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.jash.2017.06.004","article-title":"Global prevalence of hypertension among people living with HIV: a systematic review and meta-analysis","volume":"11","author":"Y Xu","year":"2017","journal-title":"J Am Soc Hypertens"},{"issue":"9","key":"pone.0315027.ref011","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1097\/HJH.0000000000002446","article-title":"Global burden of hypertension among people living with HIV in the era of increased life expectancy: a systematic review and meta-analysis","volume":"38","author":"JJ Bigna","year":"2020","journal-title":"J Hypertens"},{"key":"pone.0315027.ref012","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12916-014-0125-2","article-title":"Hypertension, kidney disease, HIV and antiretroviral therapy among Tanzanian adults: a cross-sectional study.","volume":"12","author":"RN Peck","year":"2014","journal-title":"BMC Med."},{"issue":"12","key":"pone.0315027.ref013","doi-asserted-by":"crossref","first-page":"3747","DOI":"10.1080\/17441692.2022.2049344","article-title":"Prevalence and predictors of uncontrolled hypertension, diabetes, and obesity among adults with HIV in northern Tanzania.","volume":"17","author":"JT Hertz","year":"2022","journal-title":"Glob Public Health."},{"key":"pone.0315027.ref014","doi-asserted-by":"crossref","first-page":"285","DOI":"10.11604\/pamj.2022.41.285.26952","article-title":"Hypertension among adults enrolled in HIV care in northern Tanzania: comorbidities, cardiovascular risk, and knowledge, attitudes and practices.","volume":"41","author":"P Manavalan","year":"2022","journal-title":"Pan Afr Med J."},{"issue":"1","key":"pone.0315027.ref015","doi-asserted-by":"crossref","first-page":"38","DOI":"10.5334\/gh.1127","article-title":"Prevalence and Correlates of Ischemic ECG Findings among Adults With and Without HIV in Tanzania.","volume":"17","author":"S Prattipati","year":"2022","journal-title":"Glob Heart"},{"issue":"11","key":"pone.0315027.ref016","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1161\/CIRCULATIONAHA.117.033369","article-title":"Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis","volume":"138","author":"ASV Shah","year":"2018","journal-title":"Circulation"},{"issue":"0 1","key":"pone.0315027.ref017","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1097\/QAD.0b013e3283558526","article-title":"The impact of antiretroviral treatment on the age composition of the HIV epidemic in sub-Saharan Africa","volume":"26","author":"JA Hontelez","year":"2012","journal-title":"Aids"},{"issue":"4","key":"pone.0315027.ref018","doi-asserted-by":"crossref","first-page":"e279","DOI":"10.1016\/S2352-3018(20)30036-9","article-title":"HIV and cardiovascular disease","volume":"7","author":"K So-Armah","year":"2020","journal-title":"Lancet HIV"},{"issue":"5","key":"pone.0315027.ref019","doi-asserted-by":"crossref","first-page":"e0285472","DOI":"10.1371\/journal.pone.0285472","article-title":"Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study","volume":"18","author":"FM Sakita","year":"2023","journal-title":"PLoS One"},{"issue":"12","key":"pone.0315027.ref020","doi-asserted-by":"crossref","first-page":"e0243059","DOI":"10.1371\/journal.pone.0243059","article-title":"\"It\u2019s because I think too much\": Perspectives and experiences of adults with hypertension engaged in HIV care in northern Tanzania.","volume":"15","author":"P Manavalan","year":"2020","journal-title":"PLoS One"},{"key":"pone.0315027.ref021","doi-asserted-by":"crossref","first-page":"23259582211052399","DOI":"10.1177\/23259582211052399","article-title":"Hypertension Care for People With HIV in Tanzania: Provider Perspectives and Opportunities for Improvement.","volume":"20","author":"P Manavalan","year":"2021","journal-title":"J Int Assoc Provid AIDS Care"},{"issue":"12","key":"pone.0315027.ref022","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1111\/tmi.13690","article-title":"Knowledge, attitudes, and preventive practices regarding ischemic heart disease among HIV-positive individuals in northern Tanzania","volume":"26","author":"S Prattipati","year":"2021","journal-title":"Trop Med Int Health"},{"issue":"1","key":"pone.0315027.ref023","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1177\/09564624231199507","article-title":"Patient and provider perspectives on barriers to myocardial infarction care among persons with human immunodeficiency virus in Tanzania: A qualitative study","volume":"35","author":"S Prattipati","year":"2024","journal-title":"Int J STD AIDS"},{"issue":"8","key":"pone.0315027.ref024","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1111\/jch.14518","article-title":"A community health worker delivered intervention to address hypertension among adults engaged in HIV care in northern Tanzania: Outcomes from a pilot feasibility study","volume":"24","author":"P Manavalan","year":"2022","journal-title":"J Clin Hypertens (Greenwich)."},{"issue":"10","key":"pone.0315027.ref025","doi-asserted-by":"crossref","first-page":"e005983","DOI":"10.1136\/bmjopen-2014-005983","article-title":"Task shifting interventions for cardiovascular risk reduction in low-income and middle-income countries: a systematic review of randomised controlled trials","volume":"4","author":"G Ogedegbe","year":"2014","journal-title":"BMJ Open"},{"issue":"8","key":"pone.0315027.ref026","doi-asserted-by":"crossref","first-page":"e103754","DOI":"10.1371\/journal.pone.0103754","article-title":"Task shifting for non-communicable disease management in low and middle income countries\u2014a systematic review.","volume":"9","author":"R Joshi","year":"2014","journal-title":"PLoS One"},{"issue":"7","key":"pone.0315027.ref027","first-page":"Cd007331","article-title":"Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy.","author":"T Kredo","year":"2014","journal-title":"Cochrane Database Syst Rev."},{"issue":"1","key":"pone.0315027.ref028","doi-asserted-by":"crossref","DOI":"10.1186\/s12913-018-3059-0","article-title":"Retention of medical doctors at the district level: a qualitative study of experiences from Tanzania.","volume":"18","author":"N Sirili","year":"2018","journal-title":"BMC Health Services Research."},{"issue":"5","key":"pone.0315027.ref029","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.1016\/S2214-109X(14)70033-6","article-title":"Preparedness of Tanzanian health facilities for outpatient primary care of hypertension and diabetes: a cross-sectional survey","volume":"2","author":"R Peck","year":"2014","journal-title":"Lancet Glob Health"},{"issue":"1","key":"pone.0315027.ref030","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5334\/ijic.5839","article-title":"Integrating Care for Diabetes and Hypertension with HIV Care in Sub-Saharan Africa: A Scoping Review.","volume":"22","author":"G McCombe","year":"2022","journal-title":"Int J Integr Care"},{"issue":"6","key":"pone.0315027.ref031","doi-asserted-by":"crossref","first-page":"1690s","DOI":"10.3945\/ajcn.111.019075","article-title":"Chronic noncommunicable diseases and HIV-AIDS on a collision course: relevance for health care delivery, particularly in low-resource settings\u2014insights from South Africa","volume":"94","author":"NS Levitt","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"pone.0315027.ref032","volume-title":"Chronic care of HIV and noncommunicable disease: How to leverage the HIV experience.","author":"UNAIDS","year":"2011"},{"issue":"1","key":"pone.0315027.ref033","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1097\/QAI.0b013e3181605df1","article-title":"The ADAPT-ITT model: a novel method of adapting evidence-based HIV Interventions.","volume":"47","author":"GM Wingood","year":"2008","journal-title":"J Acquir Immune Defic Syndr"},{"key":"pone.0315027.ref034","author":"S Boller","year":"2020","journal-title":"Design Thinking for Training and Development: Creating Learning Journeys That Get Results: Association for Talent Development"},{"issue":"1","key":"pone.0315027.ref035","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/1524839919850557","article-title":"Enhancing Community-Based Participatory Research Through Human-Centered Design Strategies.","volume":"21","author":"E Chen","year":"2020","journal-title":"Health Promot Pract."},{"key":"pone.0315027.ref036","article-title":"Human-centered design in international development: A review of what works and what doesn\u2019t.","author":"JR Rathi Mani-Kandt","year":"2021","journal-title":"itad"},{"issue":"8","key":"pone.0315027.ref037","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1056\/NEJMoa1911965","article-title":"A Community-Based Intervention for Managing Hypertension in Rural South Asia","volume":"382","author":"TH Jafar","year":"2020","journal-title":"N Engl J Med"},{"issue":"11","key":"pone.0315027.ref038","doi-asserted-by":"crossref","first-page":"e0140550","DOI":"10.1371\/journal.pone.0140550","article-title":"Control of Blood Pressure and Risk Attenuation: Post Trial Follow-Up of Randomized Groups.","volume":"10","author":"TH Jafar","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"pone.0315027.ref039","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1097\/HJH.0000000000001014","article-title":"Control of blood pressure and risk attenuation: a public health intervention in rural Bangladesh, Pakistan, and Sri Lanka: feasibility trial results","volume":"34","author":"TH Jafar","year":"2016","journal-title":"J Hypertens"},{"issue":"5","key":"pone.0315027.ref040","doi-asserted-by":"crossref","first-page":"e660","DOI":"10.1016\/S2214-109X(21)00033-4","article-title":"Budget impact and cost-effectiveness analyses of the COBRA-BPS multicomponent hypertension management programme in rural communities in Bangladesh, Pakistan, and Sri Lanka.","volume":"9","author":"EA Finkelstein","year":"2021","journal-title":"Lancet Glob Health."},{"issue":"1","key":"pone.0315027.ref041","doi-asserted-by":"crossref","first-page":"e0211100","DOI":"10.1371\/journal.pone.0211100","article-title":"Patients\u2019 experiences on accessing health care services for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: A qualitative study.","volume":"14","author":"H Legido-Quigley","year":"2019","journal-title":"PLoS One."},{"issue":"9","key":"pone.0315027.ref042","doi-asserted-by":"crossref","first-page":"593","DOI":"10.7326\/0003-4819-151-9-200911030-00004","article-title":"Community-based interventions to promote blood pressure control in a developing country: a cluster randomized trial","volume":"151","author":"TH Jafar","year":"2009","journal-title":"Ann Intern Med"},{"issue":"15","key":"pone.0315027.ref043","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1161\/CIRCULATIONAHA.111.039990","article-title":"Cost-effectiveness of community-based strategies for blood pressure control in a low-income developing country: findings from a cluster-randomized, factorial-controlled trial","volume":"124","author":"TH Jafar","year":"2011","journal-title":"Circulation"},{"issue":"1","key":"pone.0315027.ref044","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s13063-017-2018-0","article-title":"Multicomponent intervention versus usual care for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: study protocol for a cluster randomized controlled trial.","volume":"18","author":"TH Jafar","year":"2017","journal-title":"Trials"},{"issue":"10205","key":"pone.0315027.ref045","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0140-6736(19)31995-6","article-title":"Parallel community solutions for cardiovascular risk reduction","volume":"394","author":"TH Jafar","year":"2019","journal-title":"Lancet"},{"issue":"9","key":"pone.0315027.ref046","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.2105\/AJPH.89.9.1322","article-title":"Evaluating the public health impact of health promotion interventions: the RE-AIM framework.","volume":"89","author":"RE Glasgow","year":"1999","journal-title":"Am J Public Health"},{"key":"pone.0315027.ref047","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fpubh.2019.00064","article-title":"RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review.","volume":"7","author":"RE Glasgow","year":"2019","journal-title":"Front Public Health."},{"issue":"2","key":"pone.0315027.ref048","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1207\/s15324796abm2802_1","article-title":"RE-AIM: evidence-based standards and a Web resource to improve translation of research into practice.","volume":"28","author":"DA Dzewaltowski","year":"2004","journal-title":"Ann Behav Med"},{"issue":"11","key":"pone.0315027.ref049","doi-asserted-by":"crossref","first-page":"e018829","DOI":"10.1136\/bmjopen-2017-018829","article-title":"Epidemiology of hypertension in Northern Tanzania: a community-based mixed-methods study","volume":"7","author":"SW Galson","year":"2017","journal-title":"BMJ Open"},{"key":"pone.0315027.ref050","article-title":"The Tanzania HIV Impact Survey 2022\u20132023 (THIS)\u2014Final Report.","author":"S. NBo","year":"2023","journal-title":"Tanzania National Bureau of Statistics"},{"issue":"3","key":"pone.0315027.ref051","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.3390\/ijerph9031018","article-title":"Hypertension Knowledge-Level Scale (HK-LS): a study on development, validity and reliability.","volume":"9","author":"SB Erkoc","year":"2012","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"pone.0315027.ref052","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s13012-017-0635-3","article-title":"Psychometric assessment of three newly developed implementation outcome measures.","volume":"12","author":"BJ Weiner","year":"2017","journal-title":"Implement Sci"},{"issue":"1","key":"pone.0315027.ref053","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s12913-017-2031-8","article-title":"Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework","volume":"17","author":"M Sekhon","year":"2017","journal-title":"BMC Health Serv Res"},{"key":"pone.0315027.ref054","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brat.2015.03.009","article-title":"Therapist competence in global mental health: Development of the ENhancing Assessment of Common Therapeutic factors (ENACT) rating scale.","volume":"69","author":"BA Kohrt","year":"2015","journal-title":"Behav Res Ther."},{"issue":"12","key":"pone.0315027.ref055","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/MLR.0b013e318269e121","article-title":"Initial validation of a self-report measure of the extent of and reasons for medication nonadherence.","volume":"50","author":"CI Voils","year":"2012","journal-title":"Med Care"},{"issue":"1","key":"pone.0315027.ref056","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.gheart.2015.12.003","article-title":"Comparison of Nonblood-Based and Blood-Based Total CV Risk Scores in Global Populations.","volume":"11","author":"TA Gaziano","year":"2016","journal-title":"Glob Heart"},{"issue":"5","key":"pone.0315027.ref057","doi-asserted-by":"crossref","first-page":"e20416","DOI":"10.1371\/journal.pone.0020416","article-title":"A comparative assessment of non-laboratory-based versus commonly used laboratory-based cardiovascular disease risk scores in the NHANES III population.","volume":"6","author":"A Pandya","year":"2011","journal-title":"PLoS One"},{"key":"pone.0315027.ref058","doi-asserted-by":"crossref","first-page":"112516","DOI":"10.1016\/j.psychres.2019.112516","article-title":"Qualitative methods in implementation research: An introduction.","volume":"280","author":"AB Hamilton","year":"2019","journal-title":"Psychiatry Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T18:32:44Z","timestamp":1734460364000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315027"}},"subtitle":[],"editor":[{"given":"Steve","family":"Zimmerman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,12,17]]},"references-count":58,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0315027","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,17]]}}}