{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T05:29:09Z","timestamp":1734067749550,"version":"3.30.2"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea (NRF) grant funded by the Korean Government","award":["2022R1F1A1065215"],"award-info":[{"award-number":["2022R1F1A1065215"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>Liver compression (LC) has been proposed to predict fluid responsiveness in human pediatric patients. Because the evaluation of fluid responsiveness through LC depends on the mechanism of increased intra-abdominal pressure (IAP), understanding the impact of LC on IAP, cardiac output (CO), and respiratory parameters is essential. Thus, this study aimed to investigate the effects of LC on these parameters.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The present study used six healthy beagles. All dogs were anesthetized with isoflurane and allowed to breathe spontaneously in dorsal recumbency. After instrumentation, LC was performed at four different pressures in a sequential, non-randomized manner: (1) 10 mmHg, approximately half of the minimum value within the range; (2) 22 mmHg, a commonly used pressure within the range; (3) 44 mmHg, twice the pressure of the minimum value within the range; and (4) 60 mmHg, twice the pressure of the maximum value within the range. At each pressure, CO via transthoracic echocardiography, IAP, and cardiorespiratory parameters were measured before, during, and after LC.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Overall, our results showed that the IAP was significantly increased at all pressures during LC (P &lt; 0.001), yielding a linear correlation between LC pressure and IAP (P &lt; 0.001; r\u00b2 = 0.89). The maximum IAP during LC was 7 mmHg, and intra-abdominal hypertension was not induced. LC at 22 mmHg significantly increased the IAP by 1.7 mmHg, but did not significantly alter the CO or respiratory parameters.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>This is the first study to evaluate the effects of LC on IAP, CO, and respiratory parameters in healthy, anesthetized, and spontaneously breathing dogs. Our findings indicate that applying LC with a commonly used pressure may have a low risk of inducing intra-abdominal hypertension and related complications. Further studies are required to explore the use of LC in various clinical settings.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0315491","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T18:37:27Z","timestamp":1734028647000},"page":"e0315491","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of changes in intra-abdominal pressure and cardiac output induced by liver compression in healthy anesthetized spontaneously breathing dogs"],"prefix":"10.1371","volume":"19","author":[{"given":"Daeyun","family":"Seo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seongsoo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beomkwan","family":"Namgoong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heesung","family":"Uhm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeajeong","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seunghun","family":"Heo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hwan","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheyoun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayoung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3150-591X","authenticated-orcid":true,"given":"Jiwoong","family":"Her","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7467-496X","authenticated-orcid":true,"given":"Min Su","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"pone.0315491.ref001","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/vec.13125","article-title":"Pathophysiology of intraabdominal hypertension and abdominal compartment syndrome and relevance to veterinary critical care","volume":"32","author":"AK Gardner","year":"2022","journal-title":"J Vet Emerg Crit Care"},{"issue":"6","key":"pone.0315491.ref002","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.bja.2018.06.030","article-title":"Diagnostic accuracy of a calibrated abdominal compression to predict fluid responsiveness in children","volume":"121","author":"M Jacquet-Lagr\u00e8ze","year":"2018","journal-title":"Br J Anaesth"},{"issue":"9","key":"pone.0315491.ref003","first-page":"939","article-title":"Prediction of fluid responsiveness based on liver compression-induced blood pressure changes in children after cardiac surgery","volume":"83","author":"JH Lee","year":"2017","journal-title":"Minerva Anestesiol"},{"issue":"5","key":"pone.0315491.ref004","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/pan.14417","article-title":"Prediction of fluid responsiveness following liver compression in pediatric patients with single ventricle physiology","volume":"32","author":"JH Lee","year":"2022","journal-title":"Paediatr Anaesth"},{"issue":"10","key":"pone.0315491.ref005","article-title":"Evaluation of fluid responsiveness using liver compression in dogs with experimentally induced hypovolemia","volume":"85","author":"DY Seo","year":"2024","journal-title":"Am J Vet Res"},{"issue":"5","key":"pone.0315491.ref006","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1152\/jappl.1999.86.5.1651","article-title":"Influence of increased abdominal pressure on steady-state cardiac performance","volume":"86","author":"Y Kitano","year":"1999","journal-title":"J Appl Physiol"},{"issue":"S1","key":"pone.0315491.ref007","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1532-950X.2014.12198.x","article-title":"Cardiorespiratory Changes and Pain Response of Lift Laparoscopy Compared to Capnoperitoneum Laparoscopy in Dogs","volume":"44","author":"BA Fransson","year":"2015","journal-title":"Vet Surg"},{"issue":"8","key":"pone.0315491.ref008","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.2460\/ajvr.1993.54.08.1352","article-title":"Effects of abdominal insufflation with nitrous oxide on cardiorespiratory measurements in spontaneously breathing isoflurane-anesthetized dogs","volume":"54","author":"ME Gross","year":"1993","journal-title":"Am J Vet Res"},{"issue":"7","key":"pone.0315491.ref009","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1007\/s00134-013-2906-z","article-title":"Intra-abdominal hypertension and the abdominal compartment syndrome: Updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome","volume":"39","author":"AW Kirkpatrick","year":"2013","journal-title":"Intensive Care Med"},{"issue":"2","key":"pone.0315491.ref010","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/01.CCM.0000153408.09806.1B","article-title":"Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: A multiple-center epidemiological study","volume":"33","author":"MLNG Malbrain","year":"2005","journal-title":"Crit Care Med"},{"key":"pone.0315491.ref011","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/j.1476-4431.2012.00799.x","article-title":"Measurement of intra-abdominal pressure in dogs and cats","volume":"22","author":"SE Smith","year":"2012","journal-title":"J Vet Emerg Crit Care"},{"issue":"4","key":"pone.0315491.ref012","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/jvim.13984","article-title":"Comparison of Transpulmonary Thermodilution and Calibrated Pulse Contour Analysis with Pulmonary Artery Thermodilution Cardiac Output Measurements in Anesthetized Dogs","volume":"30","author":"NA Garofalo","year":"2016","journal-title":"J Vet Intern Med"},{"issue":"1","key":"pone.0315491.ref013","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0002-9343(00)00443-5","article-title":"The abdominojugular reflux sign","volume":"109","author":"J. Wiese","year":"2000","journal-title":"Am J Med"},{"issue":"2","key":"pone.0315491.ref014","first-page":"118","article-title":"Assisted circulation by phasic external lower body compression","volume":"64","author":"HA Heck","year":"1981","journal-title":"Circulation"},{"issue":"2","key":"pone.0315491.ref015","doi-asserted-by":"crossref","first-page":"222.e1","DOI":"10.1016\/j.jcrc.2011.08.010","article-title":"The evaluation of the effect of body positioning on intra-abdominal pressure measurement and the effect of intra-abdominal pressure at different body positioning on organ function and prognosis in critically ill patients","volume":"27","author":"M Yi","year":"2012","journal-title":"J Crit Care"},{"issue":"2","key":"pone.0315491.ref016","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1476-4431.2006.00219.x","article-title":"Abdominal compartment syndrome in a dog with babesiosis","volume":"17","author":"KE Joubert","year":"2007","journal-title":"J Vet Emerg Crit Care"},{"key":"pone.0315491.ref017","unstructured":"Conzemius MG, Sammarco JL, Holt DE, Smith GK. Clinical Determination of Preoperative and Postoperative Intra-abdominal Pressures in Dogs."},{"key":"pone.0315491.ref018","unstructured":"Silverstein DC, Hopper K. Small Animal Critical Care Medicine. 3rd ed."},{"issue":"3","key":"pone.0315491.ref019","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/vec.12953","article-title":"Comparison of right lateral versus left lateral versus sternal recumbence intra-abdominal pressure measurements in normal dogs","volume":"30","author":"KH Lapa","year":"2020","journal-title":"J Vet Emerg Crit Care"},{"key":"pone.0315491.ref020","article-title":"Relationship between abdominal pressure, pulmonary compliance, and cardiac preload in a porcine model","volume":"2012","author":"J Wauters","year":"2012","journal-title":"Crit Care Res Pract"},{"key":"pone.0315491.ref021","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1007\/s00134-019-05604-2","article-title":"A decade of progress in critical care echocardiography: a narrative review","volume":"45","author":"A Vieillard-Baron","year":"2019","journal-title":"Intensive Care Med"},{"key":"pone.0315491.ref022","article-title":"Comparative Evaluation of Cardiac Output using Echocardiography in Beagle Dogs","volume":"29","author":"K Park","year":"2012","journal-title":"J Vet Clin"},{"issue":"1","key":"pone.0315491.ref023","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-017-1737-7","article-title":"Transthoracic echocardiography: An accurate and precise method for estimating cardiac output in the critically ill patient","volume":"21","author":"P Mercado","year":"2017","journal-title":"Crit Care"},{"issue":"1","key":"pone.0315491.ref024","doi-asserted-by":"crossref","DOI":"10.1186\/s13089-018-0114-3","article-title":"Mitral valve velocity time integral and passive leg raise as a measure of volume responsiveness","volume":"10","author":"R Bou Chebl","year":"2018","journal-title":"Crit Ultrasound J"},{"key":"pone.0315491.ref025","doi-asserted-by":"crossref","DOI":"10.1186\/s13089-020-00170-x","article-title":"Rationale for using the velocity\u2013time integral and the minute distance for assessing the stroke volume and cardiac output in point-of-care settings","volume":"12","author":"P. Blanco","year":"2020","journal-title":"Ultrasound J"},{"key":"pone.0315491.ref026","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1179\/acb.2007.62.s1.026","article-title":"Abdomino-thoracic transmission during ACS: Facts and figures","author":"J Wauters","year":"2007","journal-title":"Acta Clin Belg"},{"issue":"11","key":"pone.0315491.ref027","article-title":"Cardiovascular and Respiratory Effects of Increased Intra-Abdominal Pressure with and without Dexmedetomidine in Anesthetized Dogs","volume":"10","author":"D Kim","year":"2023","journal-title":"Vet Sci"},{"key":"pone.0315491.ref028","article-title":"Factors influencing the arterial oxygen tension during halothane anaesthesia with spontaneous respiration","volume":"36","author":"JF Nunn","year":"1964","journal-title":"Br J Anaesth"},{"key":"pone.0315491.ref029","doi-asserted-by":"crossref","DOI":"10.1186\/s13613-022-01022-8","article-title":"Prediction of fluid responsiveness. What\u2019s new?","volume":"12","author":"X Monnet","year":"2022","journal-title":"Ann Intensive Care"},{"issue":"4","key":"pone.0315491.ref030","doi-asserted-by":"crossref","first-page":"388","DOI":"10.5603\/AIT.a2015.0028","article-title":"What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension","volume":"47","author":"MLNG Malbrain","year":"2015","journal-title":"Anaesthesiol Intensive Ther"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T18:37:41Z","timestamp":1734028661000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315491"}},"subtitle":[],"editor":[{"given":"Carlos Alberto Antunes","family":"Viegas","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,12,12]]},"references-count":30,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0315491","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,12]]}}}