{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T05:28:43Z","timestamp":1734586123040,"version":"3.30.2"},"reference-count":44,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["2022R1F1A1071824"],"award-info":[{"award-number":["2022R1F1A1071824"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>The relationship between obstructive sleep apnea (OSA) and hearing loss (HL) remains uncertain. This study aimed to investigate the relationship between OSA and HL, and to identify which factors play a key role.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>A retrospective review was conducted of 90 subjects diagnosed with OSA. These subjects underwent overnight polysomnography (PSG) and pure-tone audiometry at a single institution from February 2014 to November 2023. Hearing evaluations involved the comparison of OSA subjects with a non-OSA group, identified through national data utilizing the STOP-BANG questionnaire (SBQ) and age-sex 1:1 matching. Subsequently, individuals with OSA were categorized into HL and non-HL groups. Comparisons were made to ascertain differences in PSG parameters, followed by regression analysis to assess their actual impact.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The OSA group exhibited elevated hearing thresholds across all frequencies compared to the non-OSA group. Furthermore, classification of OSA subjects into the HL and non-HL groups revealed a statistically significant increase in apnea duration in the HL group for all-frequency and high-frequency cases (p = 0.038, 0.006). Multiple linear regression analysis, adjusting for age and sex, revealed a significant influence of apnea duration on HL in both all-frequency and high-frequency cases (\u00df = 0.404, p = 0.002; \u00df = 0.425, p = 0.001).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>These findings underscore the significant association between OSA and reduced auditory function, with apnea duration standing out as a crucial factor contributing to hearing loss. Our results suggest that prolonged apnea duration may be a marker of chronic hypoxic damage in patients with OSA, further clarifying its potential role in the development of hearing loss.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0315580","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T18:34:08Z","timestamp":1734546848000},"page":"e0315580","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the impact of apnea duration on the relationship between obstructive sleep apnea and hearing loss"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8624-4756","authenticated-orcid":true,"given":"Yong Seok","family":"Jo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2793-9045","authenticated-orcid":true,"given":"Jeon 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