{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T04:09:48Z","timestamp":1746850188994,"version":"3.40.5"},"reference-count":57,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS One"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>In this study we tested whether some intrapsychic behaviors of structure of personality can be associated with the onset of Type 2 diabetes (T2-DM).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>T2-DM Patients (n. 257) and Healthy subjects (n\u2009=\u2009258). Test: Social schedule (demographic variables); SASB\u2013Form- Questionnaire A (describing intrapsychic behaviors of personality structure - 8 Clusters-Cl -).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>From the logistic model emerged that in subjects with profile 2 \u201cLow Affiliation and Autonomy\u201d compared to profile 2 \u201cLow Autonomy and Self-Care\u201d considering age, education and living conditions effects, the association to the onset of diabetes increases (OR: 1.668). Subjects with profile 2 \u201cLow Affiliation and Autonomy\u201d show low assertiveness and autonomy (SASB-Cl 1); have a medium-low ability to accept and support themselves (medium-low-SASB-Cl 3,4); do not improve their leisure activities or interpersonal relationships because they are too scheduled by things to do (SASB-Cl 4, Cl5); have self-critical behavior (SASB-Cl 6 medium) and self-neglectful behavior - ignore illnesses at an emotional and physical level (Cl8). They occasionally incur in self-destructive behaviors (Cl 7). They may experience self-exhaustion and mild to moderate depression. These are the intrapsychic behaviors associated with onset of diabetes. Another variable associated with the onset of diabetes is high educational level.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>These results suggest that certain personality traits have a great association with T2-DM onset. Furthermore the analysis of intrapsychic modalities in association with the onset of diabetes could constitute a further screening aimed at primary prevention.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0315895","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T17:37:41Z","timestamp":1746812261000},"page":"e0315895","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structural analysis of social behavior: Using cluster analysis to examine personality profile associated with diabetes onset"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0503-7852","authenticated-orcid":true,"given":"Anna","family":"Vespa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Spatuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Fabbietti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-4159","authenticated-orcid":true,"given":"Mirko","family":"Di Rosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Paola","family":"Luconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Arnaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Balercia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianmaria","family":"Salvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Sarzani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Velia","family":"Giulietti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"pone.0315895.ref001","doi-asserted-by":"crossref","first-page":"109119","DOI":"10.1016\/j.diabres.2021.109119","article-title":"IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045","volume":"183","author":"H Sun","year":"2022","journal-title":"Diabetes Res Clin Pract"},{"issue":"7","key":"pone.0315895.ref002","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S","article-title":"Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation","volume":"15","author":"KG Alberti","year":"1998","journal-title":"Diabet Med"},{"issue":"11","key":"pone.0315895.ref003","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.2337\/dc12-2503","article-title":"New-onset diabetes in elderly subjects: association between HbA1c levels, mortality, and coronary revascularization","volume":"36","author":"O Twito","year":"2013","journal-title":"Diabetes Care"},{"issue":"1","key":"pone.0315895.ref004","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2337\/dc06-1267","article-title":"Cortisol secretion in patients with type 2 diabetes: relationship with chronic complications","volume":"30","author":"I Chiodini","year":"2007","journal-title":"Diabetes Care"},{"key":"pone.0315895.ref005","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jpsychores.2018.12.011","article-title":"The associations between objective and subjective health among older adults with type 2 diabetes: The moderating role of personality","volume":"117","author":"R Elran-Barak","year":"2019","journal-title":"J Psychosom Res"},{"issue":"4","key":"pone.0315895.ref006","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1177\/1099800405285748","article-title":"The association of psychological factors, physical activity, neuropathy, and quality of life in type 2 diabetes","volume":"7","author":"DA Chyun","year":"2006","journal-title":"Biol Res Nurs"},{"issue":"1","key":"pone.0315895.ref007","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.diabres.2011.10.003","article-title":"Personality traits and abnormal glucose regulation in middle-aged Swedish men and women","volume":"95","author":"A-K Eriksson","year":"2012","journal-title":"Diabetes Res Clin Pract"},{"issue":"11","key":"pone.0315895.ref008","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/j.ijnurstu.2011.04.008","article-title":"Relationships among depression, anxiety, self-care behaviour and diabetes education difficulties in patients with type-2 diabetes: a cross-sectional questionnaire survey","volume":"48","author":"S-FV Wu","year":"2011","journal-title":"Int J Nurs Stud"},{"issue":"1","key":"pone.0315895.ref009","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/01.psy.0000149256.81953.49","article-title":"DS14: standard assessment of negative affectivity, social inhibition, and Type D personality","volume":"67","author":"J Denollet","year":"2005","journal-title":"Psychosom Med"},{"issue":"4","key":"pone.0315895.ref010","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jpsychores.2012.01.006","article-title":"Type D (distressed) personality in primary care patients with type 2 diabetes: validation and clinical correlates of the DS14 assessment","volume":"72","author":"G Nefs","year":"2012","journal-title":"J Psychosom Res"},{"key":"pone.0315895.ref011","article-title":"The relationship between temperament, diabetes and depression","author":"C Gois","year":"2012","journal-title":"J Affect Disord"},{"key":"pone.0315895.ref012","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.2147\/NDT.S200012","article-title":"Personality associated with depressive status in individuals with type 2 diabetes mellitus","volume":"15","author":"N Yasui-Furukori","year":"2019","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"4","key":"pone.0315895.ref013","article-title":"Self-care and type 2 diabetes mellitus (T2DM): a literature review in sex-related differences","volume":"93","author":"I Baroni","year":"2022","journal-title":"Acta Biomed"},{"issue":"1","key":"pone.0315895.ref014","doi-asserted-by":"crossref","DOI":"10.1186\/s12991-019-0235-5","article-title":"Coping behaviors and depressive status in individuals with type 2 diabetes mellitus","volume":"18","author":"N Yasui-Furukori","year":"2019","journal-title":"Ann Gen Psychiatry"},{"issue":"3","key":"pone.0315895.ref015","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.ecl.2013.05.002","article-title":"Adverse effects of depression on glycemic control and health outcomes in people with diabetes: a review","volume":"42","author":"F Pouwer","year":"2013","journal-title":"Endocrinol Metab Clin North Am"},{"key":"pone.0315895.ref016","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.diabres.2019.04.011","article-title":"Levels of personality functioning and not depression predict decline of plasma glucose concentration in patients with type 2 diabetes mellitus","volume":"151","author":"JC Ehrenthal","year":"2019","journal-title":"Diabetes Res Clin Pract"},{"key":"pone.0315895.ref017","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12888-016-0722-z","article-title":"Psychological and personality factors in type 2 diabetes mellitus, presenting the rationale and exploratory results from The Maastricht Study, a population-based cohort study","volume":"16","author":"FEP van Dooren","year":"2016","journal-title":"BMC Psychiatry"},{"key":"pone.0315895.ref018","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jad.2017.05.018","article-title":"The interplay between diabetes, depression and affective temperaments: A structural equation model","volume":"219","author":"M Belvederi Murri","year":"2017","journal-title":"J Affect Disord"},{"issue":"3","key":"pone.0315895.ref019","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1080\/13548506.2019.1668567","article-title":"The influence of personality on trajectories of distress, health and functioning in mild-to-moderately depressed adults with type 2 diabetes","volume":"25","author":"S Sanatkar","year":"2020","journal-title":"Psychol Health Med"},{"key":"pone.0315895.ref020","doi-asserted-by":"crossref","DOI":"10.1017\/S2045796020000438","article-title":"Factors associated with the onset of major depressive disorder in adults with type 2 diabetes living in 12 different countries: results from the INTERPRET-DD prospective study","volume":"29","author":"CE Lloyd","year":"2020","journal-title":"Epidemiol Psychiatr Sci"},{"issue":"3","key":"pone.0315895.ref021","article-title":"Depression and risk of mortality in people with diabetes mellitus: a systematic review and meta-analysis","volume":"8","author":"FEP van Dooren","year":"2013","journal-title":"PLoS One"},{"key":"pone.0315895.ref022","article-title":"Epidemiology of depression in diabetes: international and cross-cultural issues","author":"CE Lloyd","year":"2012","journal-title":"J Affect Disord"},{"key":"pone.0315895.ref023","article-title":"The prevalence of co-morbid depression in adults with Type-2 diabetes: a systematic review and meta-analysis","author":"S Ali","journal-title":"Diabetic Med"},{"key":"pone.0315895.ref024","doi-asserted-by":"crossref","first-page":"2042018819865828","DOI":"10.1177\/2042018819865828","article-title":"Shared and unique risk factors for depression and diabetes mellitus in a longitudinal study, implications for prevention: an analysis of a longitudinal population sample aged \u227d45 years","volume":"10","author":"B Chireh","year":"2019","journal-title":"Ther Adv Endocrinol Metab"},{"key":"pone.0315895.ref025","article-title":"Association of depression and diabetes complications and mortality: a population-based cohort study","volume":"29","author":"C-S Wu","year":"2020","journal-title":"Epidemiol Psychiatr Sci"},{"issue":"12","key":"pone.0315895.ref026","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1111\/dme.14054","article-title":"Longitudinal associations between depression and diabetes complications: a systematic review and meta-analysis","volume":"36","author":"A Nouwen","year":"2019","journal-title":"Diabet Med"},{"issue":"2","key":"pone.0315895.ref027","doi-asserted-by":"crossref","first-page":"112","DOI":"10.2174\/157339909788166828","article-title":"Depression and quality of life in patients with diabetes: a systematic review from the European depression in diabetes (EDID) research consortium","volume":"5","author":"MT Schram","year":"2009","journal-title":"Curr Diabetes Rev"},{"key":"pone.0315895.ref028","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.diabres.2018.07.006","article-title":"Type 2 diabetes and influence of diabetes-specific distress on depression","volume":"143","author":"M Roy","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"issue":"1","key":"pone.0315895.ref029","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1186\/s12889-019-7322-z","article-title":"Severity of depression, anxious distress and the risk of type 2 diabetes - a population-based cohort study in Sweden","volume":"19","author":"A Deleskog","year":"2019","journal-title":"BMC Public Health"},{"issue":"4","key":"pone.0315895.ref030","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/psyp.12806","article-title":"Optimism moderates psychophysiological responses to stress in older people with Type 2 diabetes","volume":"54","author":"S Puig-Perez","year":"2017","journal-title":"Psychophysiology"},{"issue":"1","key":"pone.0315895.ref031","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/nop2.379","article-title":"Factors associated with subsequent diabetes-related self-care activities: The role of social support and optimism","volume":"7","author":"F Zhao","year":"2019","journal-title":"Nurs Open"},{"issue":"1","key":"pone.0315895.ref032","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00125-019-04985-9","article-title":"Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies","volume":"63","author":"Y Zhang","year":"2020","journal-title":"Diabetologia"},{"issue":"2","key":"pone.0315895.ref033","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0172126","article-title":"Stress increases the risk of type 2 diabetes onset in women: A 12-year longitudinal study using causal modelling","volume":"12","author":"ML Harris","year":"2017","journal-title":"PLoS One"},{"issue":"12","key":"pone.0315895.ref034","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1037\/hea0000003","article-title":"Personality and risk of diabetes in adults: pooled analysis of 5 cohort studies","volume":"33","author":"M Jokela","year":"2014","journal-title":"Health Psychol"},{"issue":"7","key":"pone.0315895.ref035","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1037\/hea0000730","article-title":"Psychosocial predictors of diabetes risk factors and complications: An 11-year follow-up","volume":"38","author":"VS Helgeson","year":"2019","journal-title":"Health Psychol"},{"key":"pone.0315895.ref036","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s12902-019-0463-3","article-title":"Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: a narrative review with emphasis on data from Europe","volume":"20","author":"I Kyrou","year":"2020","journal-title":"BMC Endocr Disord"},{"issue":"4","key":"pone.0315895.ref037","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1037\/0022-3514.67.4.674","article-title":"Intraindividual stability in the organization and patterning of behavior: incorporating psychological situations into the idiographic analysis of personality","volume":"67","author":"Y Shoda","year":"1994","journal-title":"J Pers Soc Psychol"},{"issue":"3","key":"pone.0315895.ref038","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1207\/S15327752JPA7903_04","article-title":"Interpersonal personality measures show circumplex structure based on new psychometric criteria","volume":"79","author":"GS Acton","year":"2002","journal-title":"J Pers Assess"},{"issue":"3","key":"pone.0315895.ref039","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1177\/1073191105276653","article-title":"Using Structural Analysis of Social Behavior (SASB) measures of self- and social perception to give interpersonal meaning to symptoms: anxiety as an exemplar","volume":"12","author":"TM Erickson","year":"2005","journal-title":"Assessment"},{"key":"pone.0315895.ref040","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1146\/annurev.clinpsy.2.022305.095337","article-title":"The use of structural analysis of social behavior (SASB) as an assessment tool","volume":"2","author":"LS Benjamin","year":"2006","journal-title":"Annu Rev Clin Psychol"},{"issue":"6","key":"pone.0315895.ref041","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1080\/00223891.2010.513286","article-title":"Assessment of repeated relational patterns for individual cases using the SASB-based Intrex questionnaire","volume":"92","author":"KL Critchfield","year":"2010","journal-title":"J Pers Assess"},{"issue":"1","key":"pone.0315895.ref042","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s10865-018-00007-y","article-title":"Psychosocial risk and management of physical diseases","volume":"42","author":"N Schneiderman","year":"2019","journal-title":"J Behav Med"},{"issue":"1","key":"pone.0315895.ref043","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2337\/cd17-0119","article-title":"Standards of Medical Care in Diabetes-2018 Abridged for Primary Care Providers","volume":"36","author":"American Diabetes Association","year":"2018","journal-title":"Clin Diabetes"},{"issue":"6","key":"pone.0315895.ref044","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066479","article-title":"educational level, obesity and incidence of diabetes among Chinese adult men and women aged 18-59 years old: an 11-year follow-up study","volume":"8","author":"X Shang","year":"2013","journal-title":"PLoS One"},{"key":"pone.0315895.ref045","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1186\/1471-2458-12-392","article-title":"Women show a closer association between educational level and hypertension or diabetes mellitus than males: a secondary analysis from the Austrian HIS","volume":"12","author":"A Kautzky-Willer","year":"2012","journal-title":"BMC Public Health"},{"issue":"5","key":"pone.0315895.ref046","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.cjca.2018.03.002","article-title":"Evolving Trends in the Epidemiology, Risk Factors, and Prevention of Type 2 Diabetes: A Review","volume":"34","author":"A Weisman","year":"2018","journal-title":"Can J Cardiol"},{"key":"pone.0315895.ref047","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/jrms.JRMS_980_18","article-title":"Comparing Mizaj (temperament) in type 1 diabetes mellitus and healthy controls: A case-control study","volume":"24","author":"R Ilkhani","year":"2019","journal-title":"J Res Med Sci"},{"key":"pone.0315895.ref048","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40780-018-0112-4","article-title":"Possible associations of personality traits representing harm avoidance and self-directedness with medication adherence in Japanese patients with type 2 diabetes","volume":"4","author":"Y Tominaga","year":"2018","journal-title":"J Pharm Health Care Sci"},{"issue":"3","key":"pone.0315895.ref049","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/wps.20771","article-title":"The clinical characterization of the adult patient with depression aimed at personalization of management","volume":"19","author":"M Maj","year":"2020","journal-title":"World Psychiatry"},{"key":"pone.0315895.ref050","doi-asserted-by":"crossref","first-page":"809015","DOI":"10.3389\/fpsyt.2021.809015","article-title":"Personality, Coping and Developmental Conditions in Female Adolescents and Young Adults with Type 1 Diabetes: Influence on Metabolic Control and Quality of Life","volume":"12","author":"G Wagner","year":"2022","journal-title":"Front Psychiatry"},{"key":"pone.0315895.ref051","doi-asserted-by":"crossref","first-page":"711","DOI":"10.3389\/fpsyt.2020.00711","article-title":"Effects of Cognitive Behavioral Therapy-Based Intervention on Improving Glycaemic, Psychological, and Physiological Outcomes in Adult Patients With Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials","volume":"11","author":"X Yang","year":"2020","journal-title":"Front Psychiatry"},{"issue":"4","key":"pone.0315895.ref052","first-page":"281","article-title":"Improving Depression, and Quality of Life in Patients with Type 2 Diabetes: Using Group Cognitive Behavior Therapy","volume":"12","author":"Z Noroozi","year":"2017","journal-title":"Iran J Psychiatry"},{"key":"pone.0315895.ref053","doi-asserted-by":"crossref","first-page":"711","DOI":"10.3389\/fpsyt.2020.00711","article-title":"Effects of Cognitive Behavioral Therapy-Based Intervention on Improving Glycaemic, Psychological, and Physiological Outcomes in Adult Patients With Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials","volume":"11","author":"X Yang","year":"2020","journal-title":"Front Psychiatry"},{"issue":"2","key":"pone.0315895.ref054","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2174\/1573399812666160607074817","article-title":"Effects of Mindfulness on Diabetes Mellitus: Rationale and Overview","volume":"13","author":"WL Medina","year":"2017","journal-title":"Curr Diabetes Rev"},{"issue":"1","key":"pone.0315895.ref055","first-page":"35","article-title":"Mind-Body Interactions and Mindfulness Meditation in Diabetes","volume":"14","author":"G Priya","year":"2018","journal-title":"Eur Endocrinol"},{"issue":"4","key":"pone.0315895.ref056","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1521\/pedi.2015.29.4.547","article-title":"Reliability, Sensitivity, and Specificity of Case Formulations for Comorbid Profiles in Interpersonal Reconstructive Therapy: Addressing Mechanisms of Psychopathology","volume":"29","author":"KL Critchfield","year":"2015","journal-title":"J Pers Disord"},{"issue":"4","key":"pone.0315895.ref057","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s11089-017-0753-5","article-title":"Psychosynthesis: A Foundational Bridge Between Psychology and Spirituality","volume":"66","author":"CA Lombard","year":"2017","journal-title":"Pastoral Psychol"}],"container-title":["PLOS One"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T17:37:54Z","timestamp":1746812274000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0315895"}},"subtitle":[],"editor":[{"given":"Jacopo","family":"Sabbatinelli","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,5,9]]},"references-count":57,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,5,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0315895","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,9]]}}}