{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T21:55:09Z","timestamp":1773957309207,"version":"3.50.1"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["FAPERJ, No. E-26\/211.104\/2021"],"award-info":[{"award-number":["FAPERJ, No. E-26\/211.104\/2021"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal","award":["CAPES, Finance Code 001; No. 88881.708719\/2022-01, and No. 88887.708718\/2022-00"],"award-info":[{"award-number":["CAPES, Finance Code 001; No. 88881.708719\/2022-01, and No. 88887.708718\/2022-00"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Asthma may lead to musculoskeletal dysfunction, including postural abnormalities. This study aimed to compare pulmonary function, body posture, and dynamic balance in young adults with childhood-onset asthma and healthy peers. This cross-sectional study included 124 participants evenly split between asthma and healthy groups. Assessments covered pulmonary function, respiratory muscle strength, postural balance, and body posture. We observed differences between groups in pulmonary function variables and respiratory muscle strength (Forced Expiratory Volume in the First Second (FEV 1); p\u2009=\u20090.005, forced vital capacity (FVC);.p\u2009=\u20090.002, peak expiratory flow rate (PEFR); p\u2009=\u20090.03) and respiratory muscle strength (maximal. expiratory pressure (MEP); p\u2009=\u20090.05). There was no difference in postural balance and body posture between groups. Moderate correlations were noted between postural balance (double leg eye closed) and pulmonary function (r\u2009=\u20090.38-0.43; p\u2009&lt;\u20090.001), but not between body posture and pulmonary function. These findings suggest childhood-onset asthma in young adults, particularly mild to moderate cases, is associated with impaired pulmonary function and respiratory muscle strength but does not significantly impact postural balance or body posture compared to healthy peers.<\/jats:p>\n<jats:p><jats:bold>Trial registration:<\/jats:bold> ClinicalTrials.gov <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT05373511\" xlink:type=\"simple\">NCT05373511<\/jats:ext-link><\/jats:p>","DOI":"10.1371\/journal.pone.0316663","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T18:27:39Z","timestamp":1741026459000},"page":"e0316663","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pulmonary function, body posture and balance in young adults with asthma: A cross-sectional study"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7596-3459","authenticated-orcid":true,"given":"Gopala Krishna","family":"Alaparthi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim Moustafa","family":"Moustafa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8598-4878","authenticated-orcid":true,"given":"Agnaldo Jos\u00e9","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7014-2002","authenticated-orcid":true,"given":"Arthur de 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