{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T05:26:51Z","timestamp":1738733211850,"version":"3.37.0"},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000323","name":"Pain Relief Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000323","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Current pharmaceutical interventions for chronic pain are reported to be minimally effective, leading researchers to investigate non-pharmaceutical avenues for chronic pain treatment. One such avenue is resizing illusions delivered using augmented reality. These illusions resize the affected body part through stretching or shrinking manipulations and have been shown to give analgesic effects; however, the neural underpinnings of these illusions remain undefined. Steady-state evoked potentials (SSEPs) have been studied within populations without chronic pain undergoing hand-based resizing illusions, finding no convincing differences in SSEP amplitudes during illusory stretching. Here, we present comparable findings from a sample with chronic pain, who are thought to have blurred cortical representations of painful body parts, but again find no clear differences in SSEP amplitude during illusory stretching. However, no significant decreases in pain ratings were found following illusory resizing, and changes in SSEP amplitudes are thought to possibly reflect experiences of illusory analgesia. Despite a lack of illusory analgesia across the sample, several participants experienced clinically meaningful levels of pain reduction following illusory resizing, highlighting the potential of resizing illusions as an analgesia treatment avenue. Subjective illusory experience data showed significantly greater experiences of the illusion in the multisensory (visuotactile) condition compared to non-illusion conditions and a unimodal visual condition, replicating findings from participants without chronic hand-based pain. Exploratory analyses using subjective disownership data show that the multisensory condition did not elicit significant disownership experiences, demonstrating that the pain reductions seen in the multisensory condition do not arise from disownership of the limb, but more likely as a direct result of the illusory resizing manipulations.<\/jats:p>","DOI":"10.1371\/journal.pone.0317693","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T18:29:33Z","timestamp":1738693773000},"page":"e0317693","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Illusory finger stretching and somatosensory responses in participants with chronic hand-based pain"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5738-6843","authenticated-orcid":true,"given":"Kirralise J.","family":"Hansford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0161-443X","authenticated-orcid":true,"given":"Daniel H.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten J.","family":"McKenzie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7158-5382","authenticated-orcid":true,"given":"Catherine E. 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